Annotation Detail

Information
Associated Genes
HMGA2
Associated Variants
HMGA2 MUTATION
HMGA2 MUTATION
Associated Disease
leukemia
Source Database
DisGeNET
Description
These findings show that HMGA2-driven leukemia in mice closely resembles spontaneous human T-ALL, indicating that HMGA2 transgenic mice should serve as an important model for investigating basic mechanisms and potential new therapies of relevance to human T-ALL.
Pubmed
25014774
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs