chr9:129110950:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr9:131,873,229-131,911,225 |
| hg38 | chr9:129,110,950-129,148,946 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | Malignant tumor of cervix | Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A... | BeFree | 25047463 | Detail |
| <0.001 | Developmental Disabilities | NA | BeFree | Detail | |
| <0.001 | colorectal carcinoma | NA | BeFree | Detail | |
| <0.001 | Diabetes Mellitus, Non-Insulin-Dependent | NA | BeFree | Detail | |
| <0.001 | Diabetic Nephropathy | Therefore, the best therapeutic approach for treatment of diabetic kidney diseas... | BeFree | 25724269 | Detail |
| <0.001 | epilepsy | De novo missense mutations in 2 subunits of serine/threonine (Ser/Thr) protein p... | BeFree | 26168268 | Detail |
| <0.001 | Heart failure | NA | BeFree | Detail | |
| 0.001 | congestive heart failure | NA | BeFree | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| <0.001 | hyperglycemia | NA | BeFree | Detail | |
| <0.001 | Orbital separation excessive | De novo missense mutations in 2 subunits of serine/threonine (Ser/Thr) protein p... | BeFree | 26168268 | Detail |
| <0.001 | leukemia | NA | BeFree | Detail | |
| <0.001 | chronic lymphocytic leukemia | NA | BeFree | Detail | |
| 0.002 | Leukemia, Myelocytic, Acute | NA | BeFree | Detail | |
| 0.001 | Myeloid Leukemia, Chronic | Silencing of CIP2A, c-Myc or E2F1 in K562 cells or CML CD34+ cells reactivates P... | BeFree | 25765543 | Detail |
| <0.001 | acute promyelocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Chronic Obstructive Airway Disease | NA | BeFree | Detail | |
| <0.001 | Lung Neoplasms | NA | BeFree | Detail | |
| 0.001 | Lupus Erythematosus, Systemic | NA | BeFree | Detail | |
| <0.001 | lymphoma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of stomach | q-PCR, Western blot and immunohistochemistry were used to explore the expression... | BeFree | 25925563 | Detail |
| 0.001 | melanoma | NA | BeFree | Detail | |
| <0.001 | multiple sclerosis | NA | BeFree | Detail | |
| <0.001 | Muscle hypotonia | De novo missense mutations in 2 subunits of serine/threonine (Ser/Thr) protein p... | BeFree | 26168268 | Detail |
| <0.001 | Neoplasm Metastasis | NA | BeFree | Detail | |
| <0.001 | Neoplasms, Experimental | Animal polyomavirus sT oncoproteins have been found to cause experimental tumors... | BeFree | 25631078 | Detail |
| <0.001 | nephroblastoma | NA | BeFree | Detail | |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| 0.001 | ovarian carcinoma | NA | BeFree | Detail | |
| <0.001 | polycystic ovary syndrome | NA | BeFree | Detail | |
| <0.001 | polycythemia vera | NA | BeFree | Detail | |
| <0.001 | Precancerous Conditions | NA | BeFree | Detail | |
| <0.001 | pulmonary emphysema | NA | BeFree | Detail | |
| <0.001 | retinoblastoma | NA | BeFree | Detail | |
| 0.120 | Stomach Neoplasms | NA | CTD_human | Detail | |
| <0.001 | Neurofibrillary degeneration (morphologic abnormality) | NA | BeFree | Detail | |
| <0.001 | Tumor Progression | NA | BeFree | Detail | |
| <0.001 | Cystadenocarcinoma, Serous | NA | BeFree | Detail | |
| <0.001 | Memory impairment | NA | BeFree | Detail | |
| 0.001 | pancreatic carcinoma | Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreati... | BeFree | 24667985 | Detail |
| 0.001 | pancreatic carcinoma | Our observations suggest potential therapeutic use of penfluridol or similar age... | BeFree | 25637283 | Detail |
| <0.001 | Malignant neoplasm of lung | NA | BeFree | Detail | |
| 0.120 | Disease Progression | NA | CTD_human | Detail | |
| <0.001 | Vesicular Stomatitis | NA | BeFree | Detail | |
| <0.001 | Metastatic melanoma | NA | BeFree | Detail | |
| <0.001 | Liver and Intrahepatic Biliary Tract Carcinoma | In addition, we demonstrated that the ability of RPIA to regulate cell prolifera... | BeFree | 25429733 | Detail |
| <0.001 | Adenocarcinoma of pancreas | Methylation of MAP3K2 prevents it from binding to the phosphatase PP2A, thereby ... | BeFree | 25382779 | Detail |
| <0.001 | cervix carcinoma | Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A... | BeFree | 25047463 | Detail |
| <0.001 | Malignant neoplasm of liver | In addition, we demonstrated that the ability of RPIA to regulate cell prolifera... | BeFree | 25429733 | Detail |
| <0.001 | Multiple malignancy | The oncoprotein Cancerous Inhibitor of PP2A (CIP2A) has been reported to interac... | BeFree | 25458953 | Detail |
| 0.001 | Malignant neoplasm of pancreas | Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreati... | BeFree | 24667985 | Detail |
| 0.001 | Malignant neoplasm of pancreas | Our observations suggest potential therapeutic use of penfluridol or similar age... | BeFree | 25637283 | Detail |
| <0.001 | Avitaminosis | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of prostate | PP2A inhibition as a novel therapeutic target in castration-resistant prostate c... | BeFree | 26234767 | Detail |
| <0.001 | Hematologic Neoplasms | NA | BeFree | Detail | |
| <0.001 | Neurodegenerative Disorders | NA | BeFree | Detail | |
| 0.003 | Hepatitis C, Chronic | NA | BeFree,LHGDN | Detail | |
| 0.003 | Carcinogenesis | NA | BeFree | Detail | |
| 0.003 | prostate carcinoma | Here, we demonstrated that Sgol1 and the C-terminus of CIP2A interact in prostat... | BeFree | 25736928 | Detail |
| 0.003 | prostate carcinoma | PP2A inhibition as a novel therapeutic target in castration-resistant prostate c... | BeFree | 26234767 | Detail |
| <0.001 | polycythemia vera | Genetic or PAD-mediated PP2A reactivation induces Jak2(V617F) inactivation/downr... | BeFree | 23926298 | Detail |
| <0.001 | Epithelial ovarian cancer | NA | BeFree | Detail | |
| 0.004 | breast carcinoma | In the present study, the protein expression levels of SET, protein phosphatase ... | BeFree | 25760096 | Detail |
| <0.001 | Carcinoma of lung | NA | BeFree | Detail | |
| 0.001 | colon carcinoma | Selective inhibition of PP2A did not significantly affect cellular apoptosis but... | BeFree | 25252130 | Detail |
| <0.001 | stomach carcinoma | q-PCR, Western blot and immunohistochemistry were used to explore the expression... | BeFree | 25925563 | Detail |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| <0.001 | spinocerebellar ataxia type 1 | NA | BeFree | Detail | |
| <0.001 | Oestrogen deficiency | NA | BeFree | Detail | |
| 0.003 | ovarian neoplasm | NA | LHGDN | Detail | |
| <0.001 | Metastatic Prostate Carcinoma | NA | BeFree | Detail | |
| <0.001 | Tauopathies | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of the head and neck | NA | BeFree | Detail | |
| <0.001 | sarcoma | NA | BeFree | Detail | |
| <0.001 | Vitamin Deficiency | NA | BeFree | Detail | |
| <0.001 | Hepatocarcinogenesis | Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK s... | BeFree | 25429733 | Detail |
| <0.001 | colorectal cancer | NA | BeFree | Detail | |
| <0.001 | androgen independent prostate cancer | NA | BeFree | Detail | |
| <0.001 | Non-Neoplastic Disorder | NA | BeFree | Detail | |
| <0.001 | Idiopathic Pulmonary Fibrosis | NA | BeFree | Detail | |
| <0.001 | Opitz-G syndrome, type 2 | NA | BeFree | Detail | |
| <0.001 | Spinocerebellar Ataxia 12 | NA | BeFree | Detail | |
| 0.001 | liver carcinoma | Previously, we found that PP2A activity determined the anticancer effect of bort... | BeFree | 25077545 | Detail |
| <0.001 | Promyelocytic leukemia | NA | BeFree | Detail | |
| <0.001 | intellectual disability | De novo missense mutations in 2 subunits of serine/threonine (Ser/Thr) protein p... | BeFree | 26168268 | Detail |
| <0.001 | Congenital Abnormality | NA | BeFree | Detail | |
| 0.001 | Alzheimer's disease | NA | BeFree | Detail | |
| <0.001 | ameloblastoma | Expression and mechanism of regulation of PP2A/Pr65 in ameloblastoma. | BeFree | 24054836 | Detail |
| <0.001 | amyotrophic lateral sclerosis | NA | BeFree | Detail | |
| <0.001 | asthma | NA | BeFree | Detail | |
| <0.001 | bipolar disorder | NA | BeFree | Detail | |
| <0.001 | Blast Phase | NA | BeFree | Detail | |
| 0.004 | Malignant neoplasm of breast | In the present study, the protein expression levels of SET, protein phosphatase ... | BeFree | 25760096 | Detail |
| 0.001 | Malignant tumor of colon | Selective inhibition of PP2A did not significantly affect cellular apoptosis but... | BeFree | 25252130 | Detail |
| <0.001 | Merkel cell carcinoma | We conclude that MCV sT is required for Merkel cell carcinoma growth, but its in... | BeFree | 25631078 | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A/NF-κB signaling in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Therefore, the best therapeutic approach for treatment of diabetic kidney disease should involve man... | DisGeNET | Detail |
| De novo missense mutations in 2 subunits of serine/threonine (Ser/Thr) protein phosphatase 2A (PP2A)... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| De novo missense mutations in 2 subunits of serine/threonine (Ser/Thr) protein phosphatase 2A (PP2A)... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Silencing of CIP2A, c-Myc or E2F1 in K562 cells or CML CD34+ cells reactivates PP2A leading to BCR-A... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| q-PCR, Western blot and immunohistochemistry were used to explore the expression of PP2A and the pho... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| De novo missense mutations in 2 subunits of serine/threonine (Ser/Thr) protein phosphatase 2A (PP2A)... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Animal polyomavirus sT oncoproteins have been found to cause experimental tumors by blocking the act... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer. | DisGeNET | Detail |
| Our observations suggest potential therapeutic use of penfluridol or similar agent associated with a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In addition, we demonstrated that the ability of RPIA to regulate cell proliferation and colony form... | DisGeNET | Detail |
| Methylation of MAP3K2 prevents it from binding to the phosphatase PP2A, thereby impeding the impact ... | DisGeNET | Detail |
| Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A/NF-κB signaling in ... | DisGeNET | Detail |
| In addition, we demonstrated that the ability of RPIA to regulate cell proliferation and colony form... | DisGeNET | Detail |
| The oncoprotein Cancerous Inhibitor of PP2A (CIP2A) has been reported to interact with Protein phosp... | DisGeNET | Detail |
| Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer. | DisGeNET | Detail |
| Our observations suggest potential therapeutic use of penfluridol or similar agent associated with a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| PP2A inhibition as a novel therapeutic target in castration-resistant prostate cancer. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we demonstrated that Sgol1 and the C-terminus of CIP2A interact in prostate carcinoma cell lin... | DisGeNET | Detail |
| PP2A inhibition as a novel therapeutic target in castration-resistant prostate cancer. | DisGeNET | Detail |
| Genetic or PAD-mediated PP2A reactivation induces Jak2(V617F) inactivation/downregulation and impair... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In the present study, the protein expression levels of SET, protein phosphatase 2A (PP2A) and phosph... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Selective inhibition of PP2A did not significantly affect cellular apoptosis but induced dose-depend... | DisGeNET | Detail |
| q-PCR, Western blot and immunohistochemistry were used to explore the expression of PP2A and the pho... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK signaling. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Previously, we found that PP2A activity determined the anticancer effect of bortezomib and erlotinib... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| De novo missense mutations in 2 subunits of serine/threonine (Ser/Thr) protein phosphatase 2A (PP2A)... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Expression and mechanism of regulation of PP2A/Pr65 in ameloblastoma. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In the present study, the protein expression levels of SET, protein phosphatase 2A (PP2A) and phosph... | DisGeNET | Detail |
| Selective inhibition of PP2A did not significantly affect cellular apoptosis but induced dose-depend... | DisGeNET | Detail |
| We conclude that MCV sT is required for Merkel cell carcinoma growth, but its in vitro transforming ... | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386626619 dbSNP
- Genome
- hg38
- Position
- chr9:129,110,950-129,148,946
- Variant Type
- snv
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