Annotation Detail
Information
- Associated Genes
- PTPA
- Associated Variants
-
PTPA MUTATION
PTPA MUTATION - Associated Disease
- Malignant neoplasm of liver
- Source Database
- DisGeNET
- Description
- In addition, we demonstrated that the ability of RPIA to regulate cell proliferation and colony formation in different liver cancer cell lines required ERK signaling as well as the negative modulation of PP2A activity and that the effects of RPIA could be modulated by the addition of either a PP2A inhibitor or activator.
- Pubmed
- 25429733
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs