Annotation Detail

Information
Associated Genes
PTPA
Associated Variants
PTPA MUTATION
PTPA MUTATION
Associated Disease
Myeloid Leukemia, Chronic
Source Database
DisGeNET
Description
Silencing of CIP2A, c-Myc or E2F1 in K562 cells or CML CD34+ cells reactivates PP2A leading to BCR-ABL suppression.
Pubmed
25765543
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs