spinocerebellar ataxia type 1
Information
- Disease name
- spinocerebellar ataxia type 1
- Disease ID
- DOID:0050954
- Description
- "An autosomal dominant cerebellar ataxia that is characterized by ataxia, dysarthria, dysphagia, dystonia and peripheral neuropathy that begins in early adulthood, has_material_basis_in the expanded (CAG)n trinucleotide repeat of ataxin-1 gene on chromosome 6p22." [url:https\://rarediseases.info.nih.gov/diseases/4071/spinocerebellar-ataxia-1]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03701399 | Active, not recruiting | Phase 3 | Troriluzole in Adult Subjects With Spinocerebellar Ataxia | March 8, 2019 | October 2025 |
| NCT03408080 | Active, not recruiting | Phase 3 | Open Pilot Trial of BHV-4157 | December 15, 2017 | December 15, 2024 |
| NCT05826171 | Active, not recruiting | N/A | Priming Motor Learning Through Exercise in People With Spinocerebellar Ataxia | February 6, 2023 | May 31, 2025 |
| NCT04268147 | Active, not recruiting | Instrumented Data Exchange for Ataxia Study | June 1, 2019 | June 30, 2024 | |
| NCT04153110 | Completed | N/A | Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia | December 1, 2018 | January 1, 2021 |
| NCT01470729 | Completed | Biomarkers in Autosomal Dominant Cerebellar Ataxia | November 2011 | December 2015 | |
| NCT03120013 | Completed | N/A | Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia | February 6, 2017 | December 1, 2018 |
| NCT03378414 | Not yet recruiting | Phase 2 | Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia | December 31, 2024 | December 31, 2025 |
| NCT01060371 | Recruiting | Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias | April 2010 | May 19, 2024 | |
| NCT01793168 | Recruiting | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford | July 2010 | December 2100 | |
| NCT05822908 | Recruiting | Phase 1/Phase 2 | A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD | February 14, 2023 | September 15, 2025 |
| NCT03487367 | Unknown status | Clinical Trial Readiness for SCA1 and SCA3 | August 16, 2018 | December 31, 2023 | |
| NCT04301284 | Withdrawn | Phase 2 | Study of CAD-1883 for Spinocerebellar Ataxia | June 2021 | December 2022 |
- Disase is a (Disease Ontology)
- DOID:1441
- Cross Reference ID (Disease Ontology)
- GARD:4071
- Cross Reference ID (Disease Ontology)
- MIM:164400
- OrphaNumber from OrphaNet (Orphanet)
- 98755