chr11:11956207:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr11:11,977,754-12,031,316 |
| hg38 | chr11:11,956,207-12,009,769 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.003 | squamous cell carcinoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Malignant tumor of cervix | NA | BeFree | Detail | |
| <0.001 | colorectal carcinoma | NA | BeFree | Detail | |
| <0.001 | Colorectal Neoplasms | NA | BeFree | Detail | |
| 0.003 | ganglioneuroma | NA | LHGDN | Detail | |
| <0.001 | glioblastoma | Blocking of the interaction between Wnt proteins and their co-receptors contribu... | BeFree | 25301448 | Detail |
| 0.004 | Glioma | The Chinese Glioma Genome Atlas (CGGA) data revealed that SNAI1 was up-regulated... | BeFree,LHGDN | 24959930 | Detail |
| <0.001 | hemangioma | To investigate the role of Dkk-1 (Dickkopf-1) and Dkk-3 in tumors and cirrhoses ... | BeFree | 25344678 | Detail |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| <0.001 | Kidney Diseases | NA | BeFree | Detail | |
| 0.002 | Kidney Neoplasm | NA | GAD | Detail | |
| <0.001 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
| <0.001 | liver cirrhosis | To investigate the role of Dkk-1 (Dickkopf-1) and Dkk-3 in tumors and cirrhoses ... | BeFree | 25344678 | Detail |
| <0.001 | Liver neoplasms | NA | BeFree | Detail | |
| 0.005 | Lung Neoplasms | NA | LHGDN | Detail | |
| <0.001 | Lupus Erythematosus, Systemic | Additionally, DKK3 limited autoimmunity in a model of systemic lupus erythematos... | BeFree | 25672757 | Detail |
| <0.001 | Malignant neoplasm of stomach | NA | BeFree | Detail | |
| <0.001 | medulloblastoma | NA | BeFree | Detail | |
| 0.006 | melanoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Neoplasm Metastasis | These findings suggest that DKK3 may be important in mediating invasion in esoph... | BeFree | 26093488 | Detail |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| 0.003 | osteosarcoma | NA | LHGDN | Detail | |
| <0.001 | ovarian carcinoma | Dkk-3 induces apoptosis through mitochondrial and Fas death receptor pathways in... | BeFree | 25514350 | Detail |
| <0.001 | Pancreatic Neoplasm | NA | BeFree | Detail | |
| 0.003 | Prostatic Neoplasms | NA | LHGDN | Detail | |
| <0.001 | Rabies (disorder) | NA | BeFree | Detail | |
| <0.001 | retinal degeneration | NA | BeFree | Detail | |
| <0.001 | RNA Virus Infections | NA | BeFree | Detail | |
| 0.003 | Stomach Neoplasms | NA | BeFree,LHGDN | Detail | |
| 0.002 | Tobacco use disorder | NA | GAD | Detail | |
| <0.001 | colorectal carcinoma | Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently... | BeFree | 18619730 | Detail |
| 0.003 | colorectal cancer | Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently... | BeFree | 18619730 | Detail |
| 0.003 | Polycystic Kidney, Autosomal Dominant | NA | BeFree,GAD | Detail | |
| <0.001 | Synovial Cyst | NA | BeFree | Detail | |
| <0.001 | cataract | In addition to these genes, all three LECs also express key lens- and cataract-a... | BeFree | 25530357 | Detail |
| <0.001 | Malignant neoplasm of testis | NA | BeFree | Detail | |
| <0.001 | Tumor Progression | NA | BeFree | Detail | |
| <0.001 | hepatoblastoma | NA | BeFree | Detail | |
| <0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
| <0.001 | Papillary thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of lung | Conversely, downregulation of DKK3 could induce parental human lung cancer cells... | BeFree | 25760729 | Detail |
| <0.001 | Simple renal cyst | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma Of Esophagus | The role of Dickkopf-3 overexpression in esophageal adenocarcinoma. | BeFree | 26093488 | Detail |
| <0.001 | cervical adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Conventional (Clear Cell) Renal Cell Carcinoma | NA | BeFree | Detail | |
| <0.001 | Solid tumour | NA | BeFree | Detail | |
| <0.001 | cervix carcinoma | NA | BeFree | Detail | |
| <0.001 | Tumor necrosis | NA | BeFree | Detail | |
| <0.001 | adenocarcinoma in situ | NA | BeFree | Detail | |
| <0.001 | malignant mesothelioma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of pancreas | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of prostate | NA | BeFree | Detail | |
| <0.001 | endometrial carcinoma | NA | BeFree | Detail | |
| <0.001 | Bilateral cataracts (disorder) | In addition to these genes, all three LECs also express key lens- and cataract-a... | BeFree | 25530357 | Detail |
| <0.001 | Thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant glioma | Integrin antagonist augments the therapeutic effect of adenovirus-mediated REIC/... | BeFree | 25394252 | Detail |
| 0.002 | Carcinogenesis | Tumorigenesis was evaluated by injecting 1 × 10(6) OE33/DKK3 and vector cells in... | BeFree | 26093488 | Detail |
| 0.002 | prostate carcinoma | NA | BeFree | Detail | |
| <0.001 | Epithelial ovarian cancer | NA | BeFree | Detail | |
| 0.002 | breast carcinoma | NA | BeFree | Detail | |
| <0.001 | Carcinoma of lung | Conversely, downregulation of DKK3 could induce parental human lung cancer cells... | BeFree | 25760729 | Detail |
| <0.001 | Secondary malignant neoplasm of lymph node | NA | BeFree | Detail | |
| <0.001 | colon carcinoma | NA | BeFree | Detail | |
| <0.001 | stomach carcinoma | NA | BeFree | Detail | |
| <0.001 | Carcinoma of bladder | NA | BeFree | Detail | |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of kidney | NA | BeFree | Detail | |
| <0.001 | Testicular malignant germ cell tumor | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of ovary | Dkk-3 induces apoptosis through mitochondrial and Fas death receptor pathways in... | BeFree | 25514350 | Detail |
| <0.001 | Myxoid cyst | NA | BeFree | Detail | |
| <0.001 | renal carcinoma | NA | BeFree | Detail | |
| 0.006 | Mammary Neoplasms | NA | BeFree,LHGDN | Detail | |
| <0.001 | Angiogenic Switch | NA | BeFree | Detail | |
| <0.001 | Primary Glioblastoma | NA | BeFree | Detail | |
| 0.003 | colorectal cancer | NA | BeFree,GAD | Detail | |
| <0.001 | Cirrhosis | To investigate the role of Dkk-1 (Dickkopf-1) and Dkk-3 in tumors and cirrhoses ... | BeFree | 25344678 | Detail |
| <0.001 | Benign Prostatic Hyperplasia | NA | BeFree | Detail | |
| <0.001 | Non-Neoplastic Disorder | We demonstrated that the miR-144-3p level was significantly down-regulated in gl... | BeFree | 26250785 | Detail |
| <0.001 | uterine corpus cancer | NA | BeFree | Detail | |
| 0.001 | liver carcinoma | Preliminary mechanism on the methylation modification of Dkk-1 and Dkk-3 in hepa... | BeFree | 25344678 | Detail |
| 0.001 | adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | adenoma | NA | BeFree | Detail | |
| <0.001 | Astrocytoma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of urinary bladder | NA | BeFree | Detail | |
| 0.003 | Bladder Neoplasm | NA | BeFree,LHGDN | Detail | |
| 0.002 | Malignant neoplasm of breast | NA | BeFree | Detail | |
| <0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of endometrium | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of thyroid | NA | BeFree | Detail | |
| 0.002 | Non-small cell lung carcinoma | DNA methylation of DKK3 modulates docetaxel chemoresistance in human nonsmall ce... | BeFree | 25760729 | Detail |
| 0.003 | renal cell carcinoma | NA | BeFree,GAD | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumo... | DisGeNET | Detail |
| The Chinese Glioma Genome Atlas (CGGA) data revealed that SNAI1 was up-regulated in glioma and we co... | DisGeNET | Detail |
| To investigate the role of Dkk-1 (Dickkopf-1) and Dkk-3 in tumors and cirrhoses of the liver tissue ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To investigate the role of Dkk-1 (Dickkopf-1) and Dkk-3 in tumors and cirrhoses of the liver tissue ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Additionally, DKK3 limited autoimmunity in a model of systemic lupus erythematosus. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These findings suggest that DKK3 may be important in mediating invasion in esophageal adenocarcinoma... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Dkk-3 induces apoptosis through mitochondrial and Fas death receptor pathways in human mucinous ovar... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently associated with col... | DisGeNET | Detail |
| Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently associated with col... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In addition to these genes, all three LECs also express key lens- and cataract-associated genes, nam... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Conversely, downregulation of DKK3 could induce parental human lung cancer cells insensitivity to do... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The role of Dickkopf-3 overexpression in esophageal adenocarcinoma. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In addition to these genes, all three LECs also express key lens- and cataract-associated genes, nam... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Integrin antagonist augments the therapeutic effect of adenovirus-mediated REIC/Dkk-3 gene therapy f... | DisGeNET | Detail |
| Tumorigenesis was evaluated by injecting 1 × 10(6) OE33/DKK3 and vector cells in NOD/SCIDγ mice. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Conversely, downregulation of DKK3 could induce parental human lung cancer cells insensitivity to do... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Dkk-3 induces apoptosis through mitochondrial and Fas death receptor pathways in human mucinous ovar... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To investigate the role of Dkk-1 (Dickkopf-1) and Dkk-3 in tumors and cirrhoses of the liver tissue ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We demonstrated that the miR-144-3p level was significantly down-regulated in glioma compared with t... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Preliminary mechanism on the methylation modification of Dkk-1 and Dkk-3 in hepatocellular carcinoma... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| DNA methylation of DKK3 modulates docetaxel chemoresistance in human nonsmall cell lung cancer cell. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386559608 dbSNP
- Genome
- hg38
- Position
- chr11:11,956,207-12,009,769
- Variant Type
- snv
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