Fluorouracil
Information
- Drug Name
- Fluorouracil
- Description
- Entry(CIViC)
- 22
CIViC
Annotation
Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
---|---|---|---|---|---|---|
49 patients gastric cancer patients treated with a... | HSPH1 | HSPH1 NUCLEAR EXPRESSION HSPH1 NUCLEAR EXPRESSION | Sensitivity | true | CIViC Evidence | detail |
329 consecutive patients with stage II–III colorec... | HSPH1 |
HSPH1 T17 DELETION ( ENST00000320027.10 ) HSPH1 T17 DELETION ( ENST00000320027.10 ) |
Sensitivity | true | CIViC Evidence | detail |
In Capan-1 cell lines engineered to reduce pRB exp... | RB1 |
RB1 OVEREXPRESSION ( ENST00000267163.6 ) RB1 OVEREXPRESSION ( ENST00000267163.6 ) |
Resitance or Non-Reponse | true | CIViC Evidence | detail |
A retrospective study with 202 colorectal cancer p... | SMAD4 |
SMAD4 LOSS ( ENST00000342988.8 ) SMAD4 LOSS ( ENST00000342988.8 ) |
Resitance or Non-Reponse | true | CIViC Evidence | detail |
A retrospective study examining the expression of ... | AURKA | AURKA EXPRESSION AURKA EXPRESSION | Sensitivity | true | CIViC Evidence | detail |
Patients with the wild type (C/C) MTHFR gene are 2... | MTHFR |
MTHFR p.Ala263Val (p.A263V) ( ENST00000376583.7, ENST00000376585.6, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 ) MTHFR p.Ala263Val (p.A263V) ( ENST00000376585.6, ENST00000376583.7, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 ) |
Sensitivity | true | CIViC Evidence | detail |
The Clinical Pharmacogenomics Implementation Conso... | DPYD |
DPYD c.1905+1G>A ( ENST00000370192.8 ) DPYD c.1905+1G>A ( ENST00000370192.8 ) |
Adverse Response | true | CIViC Evidence | detail |
The Clinical Pharmacogenomics Implementation Conso... | DPYD |
DPYD p.Ile560Ser (p.I560S) ( ENST00000370192.8 ) DPYD p.Ile560Ser (p.I560S) ( ENST00000370192.8 ) |
Adverse Response | true | CIViC Evidence | detail |
The Clinical Pharmacogenomics Implementation Conso... | DPYD | DPYD RS67376798 HOMOZYGOSITY DPYD RS67376798 HOMOZYGOSITY | Adverse Response | true | CIViC Evidence | detail |
Overall, 63% of the patients in the T-allele group... | GNAS |
GNAS p.Leu131= (p.L131=) ( ENST00000306090.12, ENST00000306120.4, ENST00000313949.11, ENST00000349036.9, ENST00000371075.7, ENST00000371098.6, ENST00000371100.9, ENST00000371102.8, ENST00000419558.7, ENST00000423897.7, ENST00000453292.7, ENST00000462499.6, ENST00000467227.6, ENST00000472183.6, ENST00000482112.6, ENST00000491348.5, ENST00000493744.5, ENST00000657090.1, ENST00000663479.2, ENST00000676826.2 ) GNAS p.Leu131= (p.L131=) ( ENST00000306090.12, ENST00000306120.4, ENST00000313949.11, ENST00000349036.9, ENST00000371075.7, ENST00000371098.6, ENST00000371100.9, ENST00000371102.8, ENST00000419558.7, ENST00000423897.7, ENST00000453292.7, ENST00000462499.6, ENST00000467227.6, ENST00000472183.6, ENST00000482112.6, ENST00000491348.5, ENST00000493744.5, ENST00000657090.1, ENST00000663479.2, ENST00000676826.2 ) |
Resitance or Non-Reponse | true | CIViC Evidence | detail |
Patient was a 35 year old male who was treated wit... | ERBB2 |
ERBB2 p.Leu755Ser (p.L755S) ( ENST00000269571.10, ENST00000406381.6, ENST00000445658.6, ENST00000541774.5, ENST00000584450.5, ENST00000584601.5 ) ERBB2 p.Leu755Ser (p.L755S) ( ENST00000269571.10, ENST00000406381.6, ENST00000445658.6, ENST00000541774.5, ENST00000584450.5, ENST00000584601.5 ) |
Sensitivity | false | CIViC Evidence | detail |
This study of 140 patients with stage II-III breas... | PIK3CA | PIK3CA MUTATION PIK3CA MUTATION | Sensitivity | false | CIViC Evidence | detail |
The MTHFR C667T variant was associated with signif... | MTHFR |
MTHFR p.Ala263Val (p.A263V) ( ENST00000376583.7, ENST00000376585.6, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 ) MTHFR p.Ala263Val (p.A263V) ( ENST00000376585.6, ENST00000376583.7, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 ) |
Sensitivity | true | CIViC Evidence | detail |
The TYMS 5' 3TPR germline variant was significantl... | TYMS | TYMS 5' TANDEM REPEAT TYMS 5' TANDEM REPEAT | Resitance or Non-Reponse | true | CIViC Evidence | detail |
EGFR amplification was not a predictor of response... | EGFR |
EGFR AMPLIFICATION ( ENST00000275493.7 ) EGFR AMPLIFICATION ( ENST00000275493.7 ) |
Sensitivity | false | CIViC Evidence | detail |
A 69 year old patient diagnosed with HNSCC present... | DPYD |
DPYD EXON 11-19 DELETION ( ENST00000370192.8 ) DPYD EXON 11-19 DELETION ( ENST00000370192.8 ) |
Sensitivity | true | CIViC Evidence | detail |
Decreased peri- and post-therapeutic expression of... | VEGFA |
VEGFA UNDEREXPRESSION ( ENST00000372055.9 ) VEGFA UNDEREXPRESSION ( ENST00000372055.9 ) |
Sensitivity | true | CIViC Evidence | detail |
Nuclear expression of DICKKOPF-1 was identified in... | DKK1 | DKK1 NUCLEAR EXPRESSION DKK1 NUCLEAR EXPRESSION | Resitance or Non-Reponse | true | CIViC Evidence | detail |
112 patients with rectal cancer who received 5-FU ... | CDKN1A | CDKN1A EXPRESSION CDKN1A EXPRESSION | Resitance or Non-Reponse | true | CIViC Evidence | detail |
112 patients with rectal cancer who received 5-FU ... | ALCAM | ALCAM EXPRESSION ALCAM EXPRESSION | Resitance or Non-Reponse | true | CIViC Evidence | detail |
41 HNSSC were analyzed by IHC for expression of EG... | CDKN1B | CDKN1B EXPRESSION CDKN1B EXPRESSION | Sensitivity | true | CIViC Evidence | detail |
Expression of GRP78 (HSPA5) in colorectal cancer p... | HSPA5 | HSPA5 EXPRESSION HSPA5 EXPRESSION | Sensitivity | true | CIViC Evidence | detail |
NCT ID | Status | Phase | Summary | Start date | Completion date |
---|---|---|---|---|---|
NCT04216290 | Active, not recruiting | Phase 2 | A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes (The INSPIRE Study) | March 17, 2021 | June 30, 2026 |
NCT05009069 | Active, not recruiting | Phase 2 | A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer | March 18, 2022 | October 30, 2026 |
NCT04937738 | Active, not recruiting | Phase 2 | Perioperative Chemotherapy in Gastric Cancer | July 21, 2021 | July 1, 2029 |
NCT04522336 | Active, not recruiting | Phase 1 | Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer | September 16, 2020 | July 18, 2024 |
NCT03337087 | Active, not recruiting | Phase 1/Phase 2 | Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer | November 2, 2018 | August 9, 2025 |
NCT05330429 | Active, not recruiting | Phase 2 | Study of Magrolimab Given Together With FOLFIRI/BEV in Patients With Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC) | July 8, 2022 | November 2026 |
NCT03329248 | Active, not recruiting | Phase 1/Phase 2 | QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy | November 6, 2017 | December 2020 |
NCT01013649 | Active, not recruiting | Phase 3 | Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery | April 5, 2010 | February 13, 2025 |
NCT04164069 | Active, not recruiting | Phase 1 | Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab | September 2, 2020 | December 31, 2023 |
NCT03193190 | Active, not recruiting | Phase 1/Phase 2 | A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer) | July 5, 2017 | October 31, 2026 |
NCT03143153 | Active, not recruiting | Phase 3 | A Study to Evaluate Efficacy in Subjects With Esophageal Cancer Treated With Nivolumab and Ipilimumab or Nivolumab Combined With Fluorouracil Plus Cisplatin Versus Fluorouracil Plus Cisplatin | June 29, 2017 | January 13, 2025 |
NCT00980460 | Active, not recruiting | Phase 3 | Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer | September 14, 2009 | March 5, 2025 |
NCT02912559 | Active, not recruiting | Phase 3 | Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair | October 16, 2017 | April 2, 2025 |
NCT03929666 | Active, not recruiting | Phase 2 | A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer | August 29, 2019 | October 30, 2026 |
NCT00873275 | Active, not recruiting | Phase 1 | Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer | March 11, 2009 | January 13, 2025 |
NCT02890355 | Active, not recruiting | Phase 2 | FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer | September 1, 2016 | March 5, 2025 |
NCT02872116 | Active, not recruiting | Phase 3 | Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer | October 12, 2016 | May 31, 2024 |
NCT04481204 | Active, not recruiting | Phase 2 | New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study | April 18, 2023 | April 6, 2025 |
NCT04094688 | Active, not recruiting | Phase 3 | Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer | September 30, 2019 | July 2025 |
NCT04363801 | Active, not recruiting | Phase 2 | A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer | July 29, 2020 | December 2025 |
NCT04068103 | Active, not recruiting | Phase 2/Phase 3 | Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery | December 16, 2019 | April 30, 2027 |
NCT03693807 | Active, not recruiting | Phase 2 | A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma | October 18, 2018 | September 2024 |
NCT02688712 | Active, not recruiting | Phase 2 | ExIST Study of LY2157299 (Galunisertib) in Rectal Cancer | March 24, 2016 | December 2025 |
NCT03586869 | Active, not recruiting | Phase 1/Phase 2 | QUILT-3.080: NANT Pancreatic Cancer Vaccine | July 28, 2018 | December 2019 |
NCT02560298 | Active, not recruiting | Phase 2 | Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer | August 23, 2016 | August 2023 |
NCT00707473 | Active, not recruiting | Phase 2 | Docetaxel, Cisplatin and Fluorouracil in Treating Patients With Previously Untreated Stage II-IV Nasal Cavity and Paranasal Sinus Cancer | June 16, 2008 | September 30, 2025 |
NCT04752696 | Active, not recruiting | Phase 2 | Onvansertib in Combination With Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants With Metastatic Pancreatic Ductal Adenocarcinoma | February 3, 2021 | March 11, 2024 |
NCT00588770 | Active, not recruiting | Phase 3 | Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma | August 8, 2008 | February 22, 2025 |
NCT00544414 | Active, not recruiting | Phase 2 | Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer | June 7, 2000 | December 30, 2024 |
NCT03533582 | Active, not recruiting | Phase 2/Phase 3 | Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery | May 24, 2018 | June 30, 2026 |
NCT04535401 | Active, not recruiting | Phase 1 | Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines | August 13, 2021 | April 29, 2025 |
NCT02419495 | Active, not recruiting | Phase 1 | Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies | June 26, 2015 | December 31, 2024 |
NCT02258659 | Active, not recruiting | Phase 2 | Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer | September 22, 2014 | December 2025 |
NCT02135419 | Active, not recruiting | Phase 3 | Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions | September 24, 2014 | March 31, 2024 |
NCT00492999 | Active, not recruiting | Phase 2 | Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver | May 2007 | May 2025 |
NCT04523818 | Active, not recruiting | Phase 1 | Short-Course Chemoradiotherapy Followed by Chemotherapy for the Treatment of Resectable Gastric Adenocarcinoma | August 11, 2020 | December 31, 2028 |
NCT05568095 | Active, not recruiting | Phase 3 | A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body | November 21, 2022 | May 2026 |
NCT00433420 | Active, not recruiting | Phase 3 | Combination Chemotherapy With or Without Fluorouracil and/or Pegfilgrastim in Treating Women With Node-Positive Breast Cancer | April 2003 | December 2025 |
NCT02135042 | Active, not recruiting | Phase 2/Phase 3 | Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA | April 21, 2014 | February 2031 |
NCT00335816 | Active, not recruiting | Phase 2 | Radiation Therapy and Fluorouracil With or Without Combination Chemotherapy Followed by Surgery in Treating Patients With Stage II or Stage III Rectal Cancer | August 2008 | December 2024 |
NCT03504397 | Active, not recruiting | Phase 3 | A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer | June 21, 2018 | March 31, 2025 |
NCT00301925 | Active, not recruiting | Phase 3 | Combination Chemotherapy in Treating Patients With Early Stage Breast Cancer That Has Been Removed By Surgery | December 16, 2005 | September 2024 |
NCT02059499 | Active, not recruiting | Phase 3 | Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions | December 28, 2015 | May 21, 2024 |
NCT03387111 | Active, not recruiting | Phase 1/Phase 2 | QUILT-3.090: NANT Squamous Cell Carcinoma (SCC) Vaccine: Subjects With SCC Who Have Progressed | January 13, 2018 | April 2021 |
NCT03837977 | Active, not recruiting | Phase 2 | Second-line Therapy for Patients With Progressive Poorly Differentiated Extra-pulmonary Neuroendocrine Carcinoma | November 13, 2018 | December 1, 2023 |
NCT03776487 | Active, not recruiting | Phase 2 | Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer | January 7, 2019 | December 30, 2026 |
NCT02047474 | Active, not recruiting | Phase 2 | Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer | March 25, 2014 | December 2026 |
NCT02037048 | Active, not recruiting | Phase 2 | FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma | February 10, 2014 | October 1, 2025 |
NCT00217737 | Active, not recruiting | Phase 3 | Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer | September 6, 2005 | September 30, 2024 |
NCT01871571 | Active, not recruiting | Phase 2 | Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer | August 2, 2013 | June 24, 2023 |
NCT01847326 | Active, not recruiting | Phase 1 | Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer | March 26, 2013 | November 4, 2027 |
NCT04761614 | Active, not recruiting | Phase 1 | Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | April 2, 2021 | December 31, 2024 |
NCT00059930 | Active, not recruiting | Phase 1 | Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer | January 2003 | June 2024 |
NCT03775265 | Active, not recruiting | Phase 3 | Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer | June 3, 2019 | June 1, 2027 |
NCT01154920 | Active, not recruiting | Phase 2 | Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma | July 9, 2010 | December 31, 2025 |
NCT03773367 | Active, not recruiting | Phase 2 | Irinotecan-based Triplet (FOLFOXIRI) as Perioperative Treatment in Resectable Gastric and Gastroesophageal Junction Adenocarcinoma. | December 14, 2018 | May 31, 2026 |
NCT04233866 | Active, not recruiting | Phase 2 | Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread | August 26, 2020 | December 31, 2025 |
NCT03736720 | Active, not recruiting | Phase 2 | Liposomal Irinotecan, Fluorouracil and Leucovorin in Treating Patients With Refractory Advanced High Grade Neuroendocrine Cancer of Gastrointestinal, Unknown, or Pancreatic Origin | June 17, 2019 | June 17, 2026 |
NCT03340896 | Active, not recruiting | Phase 3 | Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT | June 25, 2015 | November 2028 |
NCT03970252 | Active, not recruiting | Early Phase 1 | Nivolumab in Combination With Chemotherapy Pre-Surgery in Treating Patients With Borderline Resectable Pancreatic Cancer | July 24, 2019 | April 2026 |
NCT02436044 | Approved for marketing | HAIC Using Oxaliplatin Plus Fluorouracil/Leucovorin for Patients With Locally Advanced HCC | |||
NCT00003834 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer | March 1999 | December 2005 |
NCT00003835 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Stage III Colon Cancer | May 1999 | |
NCT00003862 | Completed | Phase 2 | Chemotherapy and Radiation Therapy in Treating Patients With Stomach Cancer | November 1999 | |
NCT00003873 | Completed | Phase 3 | Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer | April 1999 | |
NCT00003888 | Completed | Phase 3 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer | April 1999 | March 2015 |
NCT00003893 | Completed | Phase 3 | Adjuvant Chemotherapy Plus Radiation Therapy in Treating Women With Early-Stage Breast Cancer | July 1998 | April 2006 |
NCT00003956 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Advanced Cancer | April 1999 | December 2009 |
NCT00003994 | Completed | Phase 3 | Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver Cancer | March 1999 | |
NCT00004003 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Stage III or Stage IV Pancreatic Cancer That Cannot Be Removed by Surgery | April 1999 | August 2003 |
NCT00004005 | Completed | Phase 2 | Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin | September 1998 | October 2005 |
NCT00004059 | Completed | Phase 1 | Fluorouracil Plus UCN-01 in Treating Patients With Advanced or Refractory Solid Tumors | July 1999 | September 2002 |
NCT00004089 | Completed | Phase 2 | Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Thyroid Cancer | August 1999 | April 2002 |
NCT00004102 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | January 1999 | |
NCT00004127 | Completed | Phase 2 | Oxaliplatin Combined With Fluorouracil and Leucovorin in Treating Patients With Recurrent or Metastatic Cancer of the Esophagus or Stomach | February 2000 | August 2003 |
NCT00004150 | Completed | Phase 3 | High-Dose Fluorouracil With or Without Leucovorin Compared With Standard Fluorouracil Plus Leucovorin Following Surgery in Treating Patients With Stage III Colon Cancer | March 1999 | April 2007 |
NCT00004233 | Completed | Phase 2 | S9915 Triacetyluridine, Fluorouracil, and Leucovorin in Treating Patients With Unresectable, Locally Advanced, or Metastatic Cancer of the Esophagus or Stomach | February 2001 | January 2007 |
NCT00004242 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors | October 1999 | |
NCT00004252 | Completed | Phase 3 | Leucovorin and Fluorouracil With or Without SU5416 in Treating Patients With Metastatic Colorectal Cancer | November 1999 | September 2007 |
NCT00004257 | Completed | Phase 1 | Oxaliplatin and Fluorouracil Plus Radiation Therapy in Treating Patients With Primary Esophageal or Stomach Cancer | January 2000 | January 2004 |
NCT00004865 | Completed | Phase 2 | Cetuximab Plus Cisplatin in Treating Patients With Metastatic or Recurrent Cancer of the Head and Neck That Has Not Responded to Cisplatin Chemotherapy | November 1999 | |
NCT00004873 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Advanced Stomach Cancer | August 1999 | July 2003 |
NCT00004885 | Completed | Phase 3 | Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients With Metastatic Colorectal Cancer | July 1999 | |
NCT00004901 | Completed | Phase 1/Phase 2 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Mouth Cancer | October 1999 | July 2004 |
NCT00004913 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Advanced Solid Tumors | January 2000 | May 2002 |
NCT00004931 | Completed | Phase 3 | Fluorouracil Plus Leucovorin With or Without Oxaliplatin in Treating Patients With Stage II or Stage III Colon Cancer | February 2000 | |
NCT00005036 | Completed | Phase 3 | Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | November 1999 | |
NCT00005050 | Completed | Phase 1/Phase 2 | Eniluracil, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Colorectal Cancer | August 1999 | |
NCT00005068 | Completed | Phase 1 | Combination Chemotherapy In Treating Patients With Metastatic or Unresectable Solid Tumors | January 2000 | June 2003 |
NCT00005586 | Completed | Phase 3 | Leucovorin and Fluorouracil Compared With Observation in Treating Patients With Colorectal Cancer That Has Been Surgically Removed | October 1997 | |
NCT00005791 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors | October 1999 | December 2009 |
NCT00005979 | Completed | Phase 3 | Combination Chemotherapy With or Without Irinotecan in Treating Patients With Stage III Colon Cancer | July 22, 1998 | September 1, 2007 |
NCT00006038 | Completed | Phase 2 | Combination Chemotherapy Followed by Surgery and Intraperitoneal Chemotherapy in Treating Patients With Locally Advanced Stomach Cancer | February 2000 | February 2003 |
NCT00006050 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver | April 4, 1999 | April 4, 2003 |
NCT00006051 | Completed | Phase 2 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer | February 1999 | September 2005 |
NCT00006094 | Completed | Phase 1/Phase 2 | Oxaliplatin, Fluorouracil, and External-Beam Radiation Therapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum | July 2000 | |
NCT00006103 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Colorectal Cancer | July 2000 | April 2002 |
NCT00006111 | Completed | Phase 2 | Surgery Plus Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Urinary Tract | April 1999 | June 2008 |
NCT00006248 | Completed | Phase 2 | S0007 - Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer | November 2000 | June 2005 |
NCT00006366 | Completed | Phase 2 | Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum | February 2001 | |
NCT00006786 | Completed | Phase 2 | Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer | November 2000 | September 2006 |
NCT00007878 | Completed | Phase 1 | Bortezomib, Fluorouracil, and Leucovorin Calcium in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery | September 2000 | |
NCT00008060 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Unresectable Metastatic Colorectal Cancer | May 2000 | December 2003 |
NCT00008294 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer | August 2000 | |
NCT00009880 | Completed | Phase 2 | Combination Chemotherapy Plus Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Esophagus or Stomach | April 2001 | |
NCT00009893 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer | May 2001 | October 2009 |
NCT00014222 | Completed | Phase 3 | Combination Chemotherapy With or Without Colony-stimulating Factors in Treating Women With Breast Cancer | December 4, 2000 | March 17, 2014 |
NCT00015886 | Completed | Phase 2 | Combination Chemotherapy in Treating Women With Breast Cancer That is Metastatic or Cannot be Treated With Surgery | January 1997 | July 2009 |
NCT00016133 | Completed | Phase 1/Phase 2 | Vaccine Therapy in Treating Patients With Stage II or Stage III Colon Cancer That Has Been Removed During Surgery | March 2001 | August 2004 |
NCT00016198 | Completed | Phase 2 | Fluorouracil and Leucovorin With or Without Oxaliplatin in Treating Patients With Recurrent Metastatic Colorectal Cancer | May 2001 | December 2010 |
NCT00016952 | Completed | Phase 2 | Irinotecan or Fluorouracil Plus Leucovorin in Treating Patients With Previously Treated Metastatic Colorectal Cancer | April 2001 | October 2009 |
NCT00016978 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Previously Treated With Irinotecan | April 2001 | |
NCT00017095 | Completed | Phase 3 | Biomarker (p53 Gene) Analysis and Combination Chemotherapy Followed by Radiation Therapy and Surgery in Treating Women With Large Operable or Locally Advanced or Inflammatory Breast Cancer | March 2001 | |
NCT00019474 | Completed | Phase 2 | Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer | March 1998 | August 2000 |
NCT00019513 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas | August 1998 | June 2004 |
NCT00020345 | Completed | Phase 2 | Combination Chemotherapy and Radiation Therapy Plus Surgery in Treating Patients With Advanced Cancer of the Pancreas | September 2000 | March 2002 |
NCT00020488 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients Who Have Advanced Solid Tumors | February 2001 | |
NCT00020501 | Completed | Phase 3 | Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver | March 2001 | January 2005 |
NCT00020787 | Completed | Phase 3 | Vaccine Therapy Plus Chemotherapy in Treating Patients With Metastatic or Locally Recurrent Stomach Cancer or Esophageal Cancer | July 2001 | December 2002 |
NCT00020917 | Completed | Phase 2 | Cetuximab Plus Combination Chemotherapy in Treating Patients With Stage IV Colorectal Cancer | February 2001 | February 2004 |
NCT00021073 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Advanced Cancer | May 2001 | |
NCT00021320 | Completed | Phase 2 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer | May 2000 | April 2009 |
NCT00021398 | Completed | Phase 2 | Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer | July 1996 | September 2018 |
NCT00022139 | Completed | Phase 2 | Radiation Therapy and Paclitaxel, Carboplatin, and Fluorouracil Followed by Esophagectomy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction | January 2002 | January 2009 |
NCT00023660 | Completed | Phase 1/Phase 2 | Radiation Therapy Plus Celecoxib, Fluorouracil, and Cisplatin in Patients With Locally Advanced Cervical Cancer | August 2001 | |
NCT00023751 | Completed | Phase 2 | Surgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal Cancer | July 2001 | April 2004 |
NCT00023959 | Completed | Phase 1 | Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer | July 2001 | |
NCT00024141 | Completed | Phase 1 | Irinotecan Followed by Fluorouracil in Treating Patients With Advanced Solid Tumors | May 2001 | January 2003 |
NCT00024349 | Completed | Phase 3 | Radiation Therapy With or Without Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer | June 2001 | April 2012 |
NCT00024427 | Completed | Phase 3 | Triacetyluridine and Fluorouracil Compared With Gemcitabine in Treating Patients With Unresectable Locally Advanced, or Metastatic Pancreatic Cancer | February 2001 | |
NCT00025090 | Completed | Phase 3 | Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer | March 2001 | August 2007 |
NCT00025142 | Completed | Phase 2 | Gefitinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Colorectal Cancer | July 2001 | November 2006 |
NCT00025337 | Completed | Phase 3 | Combination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With Advanced or Metastatic Colorectal Cancer That Has Been Previously Treated | September 2001 | |
NCT00026130 | Completed | Phase 2 | Combination Chemotherapy and Radiation Therapy in Treating Patients With Pancreatic Cancer | September 2001 | June 2010 |
NCT00026273 | Completed | Phase 3 | Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients Following Surgery for Stage III Colorectal Cancer | January 2001 | |
NCT00026364 | Completed | Phase 1 | ZD 1839 Plus Combination Chemotherapy in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Colorectal Cancer | November 2001 | |
NCT00030342 | Completed | Phase 1/Phase 2 | Biological Therapy and Chemotherapy in Treating Patients With Metastatic Kidney Cancer or Colorectal Cancer | November 2001 | January 2008 |
NCT00033735 | Completed | Phase 3 | Irofulven Compared With Fluorouracil in Treating Patients With Pancreatic Cancer | January 2000 | |
NCT00036868 | Completed | Phase 2 | Combination Chemotherapy With Trastuzumab in Treating Women With Metastatic Breast Cancer | February 2002 | February 2010 |
NCT00038402 | Completed | Phase 3 | Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer | April 2001 | July 2011 |
NCT00039208 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Colorectal Cancer | February 2002 | |
NCT00039611 | Completed | N/A | Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | May 2002 | October 2007 |
NCT00042861 | Completed | Phase 1 | UCN-01, Fluorouracil, and Leucovorin in Treating Patients With Metastatic or Unresectable Solid Tumors | August 2002 | |
NCT00042874 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors | May 2002 | |
NCT00043121 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Advanced Cancer That is Metastatic or Cannot Be Removed By Surgery | June 2002 | |
NCT00045747 | Completed | Phase 2 | UCN-01 and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer | July 2002 | September 2004 |
NCT00047099 | Completed | Phase 3 | Combination Chemotherapy in Treating Women With Breast Cancer | August 2001 | March 2012 |
NCT00047112 | Completed | Phase 3 | Surgery With or Without Radiation Therapy and Chemotherapy in Treating Patients With Esophageal Cancer | May 2002 | September 2010 |
NCT00049101 | Completed | Phase 1/Phase 2 | Erlotinib and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer | August 2002 | August 2004 |
NCT00049348 | Completed | Phase 2 | Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer | October 13, 2003 | May 2009 |
NCT00052429 | Completed | Phase 1/Phase 2 | High-Dose Radiation Therapy Plus Chemotherapy in Treating Patients With Advanced Nose or Throat Cancer | September 2002 | November 2010 |
NCT00052559 | Completed | Phase 1 | Bevacizumab, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer | August 2002 | |
NCT00052910 | Completed | Phase 3 | Chemotherapy and Radiation Therapy After Surgery in Treating Patients With Stomach or Esophageal Cancer | December 2002 | December 2016 |
NCT00053807 | Completed | Phase 3 | Interleukin-2, Interferon Alfa, and Fluorouracil Compared With Observation in Treating Patients Who Have Undergone Surgery for Kidney Cancer | February 1998 | |
NCT00053820 | Completed | Phase 3 | Interferon Alfa With or Without Interleukin-2 and Fluorouracil in Treating Patients With Advanced Metastatic Kidney Cancer | July 2002 | December 2006 |
NCT00054054 | Completed | Phase 2 | S0216, Combination Chemotherapy and RT in Treating Patients With Stage III or Stage IV Head and Neck Cancer | April 2003 | |
NCT00054587 | Completed | Phase 3 | Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer | June 2001 | December 2009 |
NCT00055601 | Completed | Phase 2 | Combination Chemotherapy and Radiation Therapy With/Without Surgery In Patients With Stage II/III Bladder Cancer | December 2002 | May 14, 2018 |
NCT00055679 | Completed | Phase 3 | Combination Chemotherapy in Treating Women With Stage I Breast Cancer | August 2002 | June 2013 |
NCT00055822 | Completed | Phase 1/Phase 2 | Combination Chemotherapy and Oblimersen in Treating Patients With Advanced Colorectal Cancer | October 2002 | October 2004 |
NCT00056030 | Completed | Phase 2 | Combination Chemotherapy Plus Cetuximab in Treating Patients With Liver Metastases From Colorectal Cancer | December 2004 | |
NCT00057785 | Completed | Phase 2 | Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer | February 2003 | December 2016 |
NCT00058201 | Completed | Phase 3 | Two Chemotherapy Regimens Compared With Observation in Treating Patients With Completely Resected Pancreatic Cancer | July 2001 | September 2010 |
NCT00000758 | Completed | Phase 3 | A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women | April 1998 | |
NCT00002470 | Completed | Phase 2 | Fluorouracil Plus Interferon Alfa in Treating Patients With Advanced Metastatic Carcinoid Tumors | September 1990 | January 2004 |
NCT00002476 | Completed | Phase 3 | Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Head and Neck Cancer | January 1990 | January 2010 |
NCT00002496 | Completed | Phase 3 | Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Cancer of the Larynx | August 1992 | November 2013 |
NCT00002523 | Completed | Phase 3 | Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed | April 1993 | January 2016 |
NCT00002524 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma | June 1993 | October 2005 |
NCT00002542 | Completed | Phase 3 | Tamoxifen in Treating Women With High-Risk Breast Cancer | July 20, 1993 | January 11, 2011 |
NCT00002551 | Completed | Phase 3 | SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed | March 1994 | October 2008 |
NCT00002570 | Completed | Phase 3 | Immediate Compared With Delayed Chemotherapy in Advanced Colorectal Cancer Without Signs or Symptoms of Disease | July 15, 1994 | February 10, 2009 |
NCT00002579 | Completed | Phase 3 | Tamoxifen Following Combination Chemotherapy in Treating Women With Operable Invasive Breast Cancer | March 1993 | |
NCT00002580 | Completed | Phase 3 | Tamoxifen, Ovarian Ablation, and/or Combination Chemotherapy in Treating Premenopausal Women With Stage I, Stage II, or Stage IIIA Invasive Breast Cancer | June 1993 | |
NCT00002581 | Completed | Phase 3 | Tamoxifen With or Without Combination Chemotherapy in Treating Postmenopausal Women With Operable Invasive Breast Cancer | June 1993 | |
NCT00002582 | Completed | Phase 3 | Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer | June 1993 | April 2007 |
NCT00002593 | Completed | Phase 3 | S9415 Chemotherapy in Patients With Stage II or III Colon Cancer That Has Been Surgically Removed | December 1994 | March 2005 |
NCT00002615 | Completed | Phase 3 | Surgery With or Without Combination Chemotherapy in Treating Patients With Stomach Cancer | June 1994 | December 2003 |
NCT00002631 | Completed | Phase 3 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Cancer of the Esophagus | June 1995 | |
NCT00002689 | Completed | Phase 2 | Radiation Therapy Plus Chemotherapy in Treating Patients With Pancreatic Cancer | September 1995 | June 2007 |
NCT00002716 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer | January 1996 | August 2006 |
NCT00002722 | Completed | Phase 2 | High-Dose Chemotherapy in Treating Patients With Advanced Stomach Cancer | January 1996 | |
NCT00002755 | Completed | Phase 3 | Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer | November 1995 | June 1999 |
NCT00002783 | Completed | Phase 2 | Combination Chemotherapy Before and After Surgery in Treating Patients With Stomach Cancer | May 1996 | January 2001 |
NCT00002784 | Completed | Phase 3 | High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Combination Chemotherapy in Treating Women With High-Risk Breast Cancer | June 1996 | December 2011 |
NCT00002828 | Completed | Phase 1 | Chemotherapy With Raltitrexed and Fluorouracil in Treating Patients With Advanced Colorectal Cancer | April 1995 | November 2001 |
NCT00002839 | Completed | Phase 3 | Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx | July 1996 | |
NCT00002842 | Completed | Phase 2 | Liver Resection and Floxuridine Plus Fluorouracil and Leucovorin in Treating Patients With Liver Metastases From Colorectal Cancer | September 1994 | May 2014 |
NCT00002870 | Completed | Phase 3 | High Dose Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Therapy in Treating Women With Locally Recurrent or Metastatic Breast Cancer | December 1994 | January 2002 |
NCT00002883 | Completed | Phase 3 | Surgery With or Without Combination Chemotherapy in Treating Patients With Cancer of the Esophagus | October 1996 | August 2010 |
NCT00002888 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Advanced Head and Neck Cancer | March 1997 | August 2004 |
NCT00002897 | Completed | Phase 3 | Surgery With or Without Chemotherapy in Treating Patients With Stage II or Stage III Cancer of the Esophagus | July 1992 | June 2001 |
NCT00002951 | Completed | Phase 2 | Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer | June 1996 | July 2006 |
NCT00002955 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Advanced Cancer of the Pancreas | August 1995 | June 2006 |
NCT00002984 | Completed | Phase 1/Phase 2 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced or Metastatic Cancer of the Esophagus | March 1997 | January 2007 |
NCT00003012 | Completed | Phase 3 | Combination Chemotherapy Following Surgery in Treating Women With Early Stage Breast Cancer | October 1996 | |
NCT00003013 | Completed | Phase 3 | Chemotherapy Plus Surgery in Treating Women With Breast Cancer | October 1996 | March 2009 |
NCT00003018 | Completed | Phase 2 | S9700 Combination Chemotherapy in Treating Patients With Stage II or Stage III Pancreatic Cancer | September 1997 | January 2007 |
NCT00003029 | Completed | Phase 3 | Fluorouracil With or Without Cisplatin in Treating Patients With Advanced or Metastatic Cancer of the Pancreas | May 1997 | |
NCT00003049 | Completed | Phase 3 | Surgery Followed by Radiation Therapy and Chemotherapy in Treating Patients With Cancer of the Pancreas | May 1997 | July 2007 |
NCT00003078 | Completed | Phase 3 | Radiation Therapy With or Without Cisplatin or Fluorouracil in Treating Patients With Cancer of the Cervix | October 1997 | |
NCT00003118 | Completed | Phase 3 | Surgery With or Without Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus | October 1997 | March 2000 |
NCT00003172 | Completed | Phase 2 | Comparison of Combination Chemotherapy Regimens in Treating Patients With Advanced Stomach Cancer | December 1997 | September 2004 |
NCT00003175 | Completed | Phase 2 | Fluorouracil in Treating Patients With Recurrent or Metastatic Bladder Cancer | December 1997 | March 2009 |
NCT00003209 | Completed | Phase 3 | Radiation Therapy With or Without Chemotherapy After Surgery in Treating Patients With Stage IB or Stage IIA Cervical Cancer | December 1997 | |
NCT00003216 | Completed | Phase 3 | Fluorouracil, Gemcitabine, and Radiation Therapy in Treating Patients With Cancer of the Pancreas | July 1998 | |
NCT00003254 | Completed | Phase 2 | SWOG-S9635 Fluorouracil Plus Ethynyluracil in Advanced Colorectal Cancer Not Responded to Fluorouracil | April 1998 | October 2003 |
NCT00003287 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer | March 1998 | |
NCT00003298 | Completed | Phase 2 | Chemotherapy, Surgery, and Radiation Therapy in Treating Patients With Gastric Cancer | June 1, 1999 | May 2011 |
NCT00003331 | Completed | Phase 1 | Combination Chemotherapy in Treating Patients With Advanced Cancer | January 1998 | |
NCT00003422 | Completed | Phase 3 | Radiation Therapy Before Surgery Compared With Chemotherapy Plus Radiation After Surgery in Treating Patients With Rectal Cancer That Can Be Surgically Removed | January 1998 | June 2010 |
NCT00003446 | Completed | Phase 2 | Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer | December 1997 | August 2005 |
NCT00003543 | Completed | Phase 1 | Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | June 1998 | August 2002 |
NCT00003549 | Completed | Phase 2 | S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer | October 1998 | January 2003 |
NCT00003576 | Completed | Phase 3 | Surgery and Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer That Can Be Removed During Surgery | January 1997 | August 2005 |
NCT00003577 | Completed | Phase 3 | Combination Chemotherapy With or Without Epirubicin in Treating Women With Stage I or Stage II Breast Cancer | March 1996 | September 2008 |
NCT00003582 | Completed | Phase 1/Phase 2 | Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer | May 1988 | December 1996 |
NCT00003585 | Completed | Phase 1/Phase 2 | Biological Therapy Plus Chemotherapy in Treating Patients With Metastatic or Recurrent Kidney Cancer | August 1996 | August 2002 |
NCT00003594 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | October 1998 | October 2004 |
NCT00003596 | Completed | Phase 3 | Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer | October 1998 | December 2016 |
NCT00003627 | Completed | Phase 3 | Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Advanced Cancer of the Oropharynx or Hypopharynx | October 1998 | January 2011 |
NCT00003652 | Completed | Phase 3 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer | January 4, 1999 | March 31, 2007 |
NCT00003730 | Completed | N/A | Vinorelbine Plus Fluorouracil in Treating Women With Metastatic Breast Cancer | December 1998 | |
NCT00003799 | Completed | Phase 1 | Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Rectal Cancer | May 1999 | |
NCT00060411 | Completed | Phase 1 | A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer | June 2003 | |
NCT00062426 | Completed | Phase 3 | Oxaliplatin and Bevacizumab (Avastin™) With Either Fluorouracil and Leucovorin or Capecitabine in Treating Patients With Advanced Colorectal Cancer | May 2003 | February 2011 |
NCT00064181 | Completed | Phase 3 | Combination Chemotherapy With or Without Celecoxib in Treating Patients With Metastatic Colorectal Cancer | May 2003 | |
NCT00066274 | Completed | Phase 2 | Comparison of Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer | July 23, 2002 | April 1, 2007 |
NCT00066846 | Completed | Phase 2 | Bevacizumab Plus Fluorouracil and Leucovorin in Treating Patients With Locally Advanced or Metastatic Stage IV Colorectal Cancer That Has Progressed After Standard Chemotherapy | August 2003 | July 2007 |
NCT00068575 | Completed | Phase 2 | Chemotherapy, Interferon Alfa, and Radiation Therapy in Treating Patients Who Have Undergone Surgery For Pancreatic Cancer | May 2002 | December 2010 |
NCT00068692 | Completed | Phase 3 | Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer | October 15, 2003 | November 15, 2016 |
NCT00069953 | Completed | Phase 2 | Combination Chemotherapy Followed By Chemoradiotherapy, With or Without Surgery, in Treating Patients With Resectable Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction | September 2003 | December 2016 |
NCT00070213 | Completed | Phase 3 | Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer | September 2003 | June 1, 2011 |
NCT00079274 | Completed | Phase 3 | Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer | February 2004 | November 2012 |
NCT00080951 | Completed | Phase 2 | Irinotecan, Fluorouracil, Leucovorin, and Oxaliplatin as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer | March 2004 | February 2008 |
NCT00080990 | Completed | Phase 1 | Alvocidib, Oxaliplatin, Fluorouracil, and Leucovorin Calcium in Treating Patients With Advanced Solid Tumors | February 2004 | |
NCT00081289 | Completed | Phase 2 | Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer | March 2004 | December 2016 |
NCT00083109 | Completed | Phase 1/Phase 2 | Fluorouracil and Low-Dose Suramin as Chemosensitization in Treating Patients With Metastatic Renal Cell (Kidney) Cancer | March 2004 | March 2008 |
NCT00084773 | Completed | N/A | Neoadjuvant Cetuximab, Fluorouracil, and Pelvic Irradiation in Treating Patients With Locally Advanced or Locally Recurrent Rectal Cancer | March 2004 | March 2010 |
NCT00085163 | Completed | Phase 3 | Celecoxib Combined With Fluorouracil and Leucovorin in Treating Patients With Resected Stage III Adenocarcinoma (Cancer) of the Colon | March 2004 | |
NCT00086996 | Completed | Phase 2 | S0356 Oxaliplatin, 5-FU, Radiation Therapy (RT), Surgery for Pts With Stage II or III Cancer of Esophagus or Gastroesophageal (GE) Junction | September 2004 | August 2011 |
NCT00087178 | Completed | Phase 3 | Comparison of Two Combination Chemotherapy Regimens in Treating Women With Breast Cancer | May 2004 | May 2016 |
NCT00089024 | Completed | Phase 2 | Combination Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer | February 25, 2004 | December 1, 2014 |
NCT00095875 | Completed | Phase 3 | Combination Chemotherapy and Radiation in Treating Patients With Stage III or IV Head and Neck Cancer (Paradigm Trial) | August 2004 | April 2012 |
NCT00096070 | Completed | Phase 2 | Radiotherapy Combined With Oxaliplatin and Fluorouracil Followed By Gemcitabine in Treating Patients With Locally Advanced, Unresectable Pancreatic Cancer | December 2004 | |
NCT00096278 | Completed | Phase 3 | Fluorouracil, Leucovorin, and Oxaliplatin With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II or Stage III Colon Cancer | September 15, 2004 | December 31, 2012 |
NCT00098787 | Completed | Phase 2 | Bevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal Cancer | September 8, 2005 | April 2015 |
NCT00098982 | Completed | Phase 1 | Bortezomib, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer | September 2004 | |
NCT00100841 | Completed | Phase 2 | Phase II Trial of FOLFOX6, Bevacizumab and Cetuximab in Patients With Colorectal Cancer | November 2004 | July 2011 |
NCT00103298 | Completed | Phase 2 | Isolated Hepatic Perfusion With Melphalan Followed by Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer | December 2004 | July 2006 |
NCT00112658 | Completed | Phase 2/Phase 3 | Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer | November 2004 | June 30, 2010 |
NCT00112697 | Completed | Phase 2 | Radiation Therapy and Docetaxel With Either Fluorouracil or Cisplatin as First-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery | October 6, 2003 | March 1, 2012 |
NCT00117572 | Completed | Phase 3 | Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE) | November 2004 | December 2016 |
NCT00118261 | Completed | Phase 1 | Erlotinib, Modified FOLFOX6, and Bevacizumab as First-Line Therapy Metastatic Colorectal Cancer | March 2005 | January 2011 |
NCT00129389 | Completed | Phase 3 | FAC Versus FAC Plus Weekly Paclitaxel as Adjuvant Treatment of Node Negative High Risk Breast Cancer Patients | September 19, 2003 | October 1, 2013 |
NCT00129922 | Completed | Phase 3 | Fluorouracil, Epirubicin, and Cyclophosphamide Alone or Followed by Paclitaxel for Early Breast Cancer | November 1999 | December 2007 |
NCT00138177 | Completed | Phase 1 | Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors | July 2005 | |
NCT00193284 | Completed | Phase 2 | Chemotherapy Plus Gefitinib Followed by Chemotherapy, Radiation Therapy, and Gefitinib For Head and Neck Cancer | October 2003 | January 2009 |
NCT00209625 | Completed | Phase 1/Phase 2 | Phase I / II Study of Irinotecan (CPT-11) Combined With l-Leucovorin (l-LV) and 5-FU in Patients With Advanced Colorectal Cancer | April 2000 | November 2004 |
NCT00252564 | Completed | Phase 3 | Cetuximab, Bevacizumab & 5FU/Leucovorin vs. Oxaliplatin, Bevacizumab & 5FU/Leucovorin in Metastatic Colorectal Cancer | September 2005 | June 2009 |
NCT00258323 | Completed | Phase 2 | Radiotherapy,Chemotherapy,Before and After Surgery in Advanced Esophageal or Gastroesophageal Junction Cancer | October 2005 | February 2010 |
NCT00262808 | Completed | Phase 2 | GM-CSF and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Colon Cancer | March 2004 | September 2006 |
NCT00268333 | Completed | Phase 2 | Combination Chemotherapy and Radiation Therapy in Treating Patients With Recurrent Metastatic Colorectal Cancer | August 2005 | |
NCT00274937 | Completed | Phase 3 | Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer | February 20, 2006 | September 30, 2022 |
NCT00280176 | Completed | Phase 1 | Bortezomib, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II, Stage III, or Stage IV Rectal Cancer | April 2003 | September 2010 |
NCT00281944 | Completed | Phase 1 | Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors | September 2005 | |
NCT00296608 | Completed | Phase 3 | Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer | April 1993 | August 2008 |
NCT00303758 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery | October 2005 | March 2012 |
NCT00303771 | Completed | Phase 3 | Combination Chemotherapy as First-Line Therapy in Treating Older Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery | June 2003 | January 2011 |
NCT00309543 | Completed | Phase 3 | Randomized Trial on Adjuvant Chemotherapy in Colon Carcinoma Dukes B | November 1993 | |
NCT00309569 | Completed | Phase 3 | Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients | October 1991 | September 2000 |
NCT00311636 | Completed | Phase 3 | Triptorelin in Preventing Early Menopause in Premenopausal Women Who Are Receiving Chemotherapy for Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery | September 2003 | April 2008 |
NCT00316888 | Completed | Phase 2 | Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer | February 28, 2007 | August 17, 2021 |
NCT00321685 | Completed | Phase 2 | Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer | July 25, 2006 | February 11, 2019 |
NCT00321828 | Completed | Phase 2 | Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colon Cancer That Cannot Be Removed By Surgery | March 2006 | December 2012 |
NCT00324415 | Completed | Phase 2 | Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer | September 2006 | May 2016 |
NCT00336960 | Completed | Phase 2 | Celecoxib, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery | July 2002 | March 2008 |
NCT00343239 | Completed | Phase 2 | Docetaxel in Locally Advanced Gastric Adenocarcinoma | June 2006 | March 2012 |
NCT00343408 | Completed | Phase 1 | AZD2171 and Standard Combination Chemotherapy in Advanced Non-Small Cell Lung Cancer or Colorectal Cancer | November 29, 2005 | September 22, 2008 |
NCT00352105 | Completed | Phase 1/Phase 2 | Cisplatin, Fluorouracil, Iressa, and Radiation Therapy Patients With Locally Advanced Head and Neck Cancer | April 2006 | May 2010 |
NCT00381862 | Completed | Phase 2 | Phase II Trial of Aprepitant & Palonosetron for CINV Prevention w FOLFOX | June 2006 | July 2008 |
NCT00408694 | Completed | Phase 2 | Bevacizumab, Cisplatin, Radiation Therapy, and Fluorouracil in Treating Patients With Stage IIB, Stage III, Stage IVA, or Stage IVB Nasopharyngeal Cancer | December 13, 2006 | December 15, 2011 |
NCT00416507 | Completed | Phase 3 | Gemcitabine With or Without Combination Chemotherapy and Radiation Therapy in Treating Patients With Nonmetastatic Pancreatic Cancer That Cannot Be Removed By Surgery | March 2000 | January 2007 |
NCT00416767 | Completed | Phase 2 | Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By Surgery | May 2004 | July 2007 |
NCT00416858 | Completed | Phase 3 | Radiation Therapy and Combination Chemotherapy With or Without Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed By Surgery | April 2007 | |
NCT00422864 | Completed | Phase 2 | A Single Arm Trial of Oxaliplatin and 5FU With Concurrent Radiation in Patients With Metastatic Rectal Cancer | October 2006 | January 2011 |
NCT00423293 | Completed | Phase 2 | Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer | December 2006 | December 2016 |
NCT00423696 | Completed | Phase 2 | Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery | March 23, 2006 | August 1, 2011 |
NCT00425152 | Completed | Phase 3 | Fluorouracil and Leucovorin and/or Levamisole After Surgery In Treating Patients With Dukes' B Or Dukes' C Colon Cancer | July 1989 | April 2004 |
NCT00427310 | Completed | Phase 3 | Liver Infusions of Fluorouracil in Treating Patients With Dukes' A, Dukes' B, or Dukes' C Colon Cancer Undergoing Surgery | March 1984 | February 2001 |
NCT00427570 | Completed | Phase 3 | Fluorouracil, Semustine, and Vincristine Compared With BCG in Treating Patients With Dukes' B or Dukes' C Colon Cancer That Has Been Removed By Surgery | September 1977 | May 2006 |
NCT00429299 | Completed | Phase 2 | Neoadjuvant Study With Chemotherapy, Lapatinib And Trastuzumab In Breast Cancer | August 2006 | June 2012 |
NCT00447967 | Completed | Phase 2 | Combination of CPT-11 and LoHP vs Combination of 5-FU, Leucovorin and LoHP as 1st Line Treatment in Gastric Patients | July 2004 | September 2008 |
NCT00449137 | Completed | Phase 1 | Arsenic Trioxide, Fluorouracil, and Leucovorin in Treating Patients With Stage IV Colorectal Cancer That Has Relapsed or Not Responded to Treatment | June 2005 | December 2010 |
NCT00462501 | Completed | N/A | Combination Chemotherapy and Bevacizumab With or Without Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer | March 2007 | February 2014 |
NCT00462735 | Completed | Phase 2 | Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer | February 2007 | October 2010 |
NCT00467142 | Completed | Phase 2 | Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery | January 23, 2007 | December 2011 |
NCT00498953 | Completed | Phase 1/Phase 2 | Combination Chemotherapy and Radiation Therapy With or Without Lapatinib in Treating Patients With Locally Advanced Cancer of the Larynx or Hypopharynx | May 2007 | March 2009 |
NCT00507585 | Completed | Phase 1 | Hepatic Arterial Infusion of Oxaliplatin, Fluorouracil, Leucovorin, and Avastin | June 2006 | January 2010 |
NCT00514020 | Completed | Phase 2 | Fluorouracil, Oxaliplatin, and Leucovorin in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction Cancer | August 2007 | February 2011 |
NCT00537121 | Completed | Phase 1 | Vorinostat, Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Upper Gastrointestinal Cancer | November 2006 | June 2013 |
NCT00541125 | Completed | Phase 2 | G-CSF in Preventing Neutropenia During First-Line Treatment With Chemotherapy and Bevacizumab in Patients With Metastatic Colorectal Cancer | November 2007 | December 2013 |
NCT00544349 | Completed | Phase 2 | Leucovorin, Fluorouracil, Cetuximab, and Oxaliplatin in Treating Patients With Stage IV Colorectal Cancer and Liver Metastases That Cannot Be Removed by Surgery | October 2006 | |
NCT00544362 | Completed | Phase 1/Phase 2 | Fluorouracil, Cisplatin, Cetuximab, and Radiation Therapy in Treating Patients With Esophageal Cancer That Can Be Removed by Surgery | July 2007 | March 2013 |
NCT00556413 | Completed | Phase 2 | Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer | September 2005 | November 17, 2011 |
NCT00557102 | Completed | Phase 2 | Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and/or Lung | September 2007 | December 2010 |
NCT00559455 | Completed | Phase 2 | Phase II Study of Eloxatin+5-FU/LV in Patients With Unresectable Hepatocellular Carcinoma | September 2007 | January 2010 |
NCT00559676 | Completed | Phase 4 | Study of Biomarkers in Patients Undergoing Chemotherapy for Metastatic Colorectal Cancer | March 2005 | |
NCT00559741 | Completed | Phase 2 | Cetuximab and Combination Chemotherapy in Treating Patients With Advanced or Metastatic Colorectal Cancer | October 2005 | |
NCT00592501 | Completed | Phase 2 | Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma | October 2006 | April 2019 |
NCT00601627 | Completed | Phase 2 | Panitumumab, Chemotherapy, and External-Beam Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot be Removed by Surgery | June 2009 | May 2013 |
NCT00601705 | Completed | Phase 2 | Epirubicin, Oxaliplatin and Fluorouracil (EOF) in Cancer of the Esophagus, Gastroesophageal Junction, or Stomach | January 5, 2008 | January 23, 2015 |
NCT00602602 | Completed | Phase 2 | Bevacizumab, Combination Chemotherapy, and Radiation Therapy in Treating Patients Undergoing Surgery For Locally Advanced Pancreatic Cancer | March 2007 | September 2011 |
NCT00608205 | Completed | Phase 3 | Radiation Therapy Cisplatin With or Without Fluorouracil Patients With Stage III or Stage IV Head and Neck Cancer | January 2008 | August 2016 |
NCT00610948 | Completed | Phase 1 | Everolimus, Fluorouracil, Leucovorin, Panitumumab, and Oxaliplatin in Treating Patients With Tumors That Did Not Respond to Treatment | March 2008 | January 2016 |
NCT00625092 | Completed | Phase 1 | Hyperthermic Intraperitoneal Oxaliplatin for Peritoneal Malignancies | October 2007 | September 2011 |
NCT00628810 | Completed | Phase 2 | Combination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | January 2007 | December 2008 |
NCT00629863 | Completed | N/A | Endoscopic Ultrasound in Diagnosing Cancer in Patients With Localized Stomach Cancer or Esophageal Cancer | September 2004 | January 2010 |
NCT00630032 | Completed | Phase 3 | Safety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer | September 2007 | September 3, 2020 |
NCT00640081 | Completed | Phase 2 | Combination Chemotherapy and Cetuximab as First-Line Therapy in Treating Patients With Advanced and/or Metastatic Colorectal Cancer | July 2007 | September 2015 |
NCT00642577 | Completed | Phase 3 | A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Chinese Patients With Metastatic Colorectal Cancer. | July 2007 | December 2010 |
NCT00654160 | Completed | Phase 1 | Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer | June 2008 | December 3, 2012 |
NCT00665392 | Completed | Phase 2 | Cetuximab and Combination Chemotherapy in Patients With Stage III-IV Resectable Oropharynx Cancer | February 2008 | July 2012 |
NCT00707889 | Completed | Phase 2 | Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer | October 2008 | May 2012 |
NCT00711243 | Completed | Phase 1/Phase 2 | Docetaxel, Oxaliplatin, and Fluorouracil in Treating Patients With Metastatic or Unresectable Stomach Cancer, Gastroesophageal Junction Cancer, or Other Solid Tumor | April 20, 2005 | February 25, 2011 |
NCT00719797 | Completed | Phase 3 | Combination Chemotherapy and Bevacizumab as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer | July 2008 | |
NCT00721513 | Completed | Phase 2 | Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer | September 2008 | August 2014 |
NCT00749450 | Completed | Phase 3 | Combination Chemotherapy After Surgery in Treating Patients With High-Risk Stage II or Stage III Colorectal Cancer | March 2008 | |
NCT00769405 | Completed | Phase 3 | Systemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer | February 2008 | |
NCT00820547 | Completed | Phase 2 | Efficacy and Tolerance Study of Bevacizumab in Her2- Inflammatory Breast Cancer Patients | January 2009 | September 2019 |
NCT00872625 | Completed | Phase 1 | Radiation Therapy and Docetaxel Followed by Standard Therapy in Treating Women With Breast Cancer | April 2007 | December 2010 |
NCT00896181 | Completed | Phase 2 | Phase 2 Sequential and Concurrent Chemoradiation for Advanced Nasopharyngeal Carcinoma (NPC) | December 10, 2008 | December 2020 |
NCT00929591 | Completed | Phase 3 | SWOG-8814 Tamoxifen With or Without Combination Chemotherapy in Postmenopausal Women Who Have Undergone Surgery for Breast Cancer | May 1989 | March 2010 |
NCT00938470 | Completed | Phase 2 | Docetaxel, Oxaliplatin, Capecitabine, Fluorouracil, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction | January 2010 | March 2018 |
NCT00942266 | Completed | Phase 2 | Vorinostat, Fluorouracil, and Leucovorin Calcium in Treating Patients With Metastatic Colorectal Cancer That Has Not Responded to Previous Treatment | July 2009 | December 2011 |
NCT00952029 | Completed | Phase 2/Phase 3 | Combination Chemotherapy and Bevacizumab With or Without Bevacizumab Maintenance Therapy in Treating Patients With Metastatic Colorectal Cancer | March 2010 | January 2018 |
NCT00957905 | Completed | Phase 2 | Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors | June 2009 | August 2014 |
NCT00960284 | Completed | Phase 2/Phase 3 | Gemcitabine or Combination Chemotherapy Followed by Chemoradiation for Stage IB, II, or III Pancreatic Cancer | June 2003 | June 2009 |
NCT00963729 | Completed | Phase 3 | Chemotherapy or Letrozole Before Surgery in Treating Postmenopausal Women With Breast Cancer That Can Be Removed By Surgery | September 2008 | March 2011 |
NCT00975897 | Completed | Phase 2/Phase 3 | Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer | July 2009 | December 2012 |
NCT00982592 | Completed | Phase 2 | Combination Chemotherapy With or Without Vismodegib in Treating Patients With Advanced Stomach Cancer or Gastroesophageal Junction Cancer | September 2009 | October 2014 |
NCT01013805 | Completed | Phase 2 | Preoperative Radiotherapy and Chemotherapy in Patients With Locally Advanced Rectal Cancer | November 2009 | December 2012 |
NCT01041404 | Completed | Phase 3 | ToGA Study - A Study of Herceptin (Trastuzumab) in Combination With Chemotherapy Compared With Chemotherapy Alone in Patients With HER2-Positive Advanced Gastric Cancer | September 2005 | June 2010 |
NCT01068327 | Completed | Phase 1 | Stereotactic Radiation, Nelfinavir Mesylate & Neoadjuvant Chemotherapy in Locally Advanced Pancreatic Cancer | November 5, 2007 | February 1, 2015 |
NCT01164215 | Completed | Phase 1 | Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy | February 2010 | September 2013 |
NCT01205022 | Completed | Phase 1 | Radiolabeled Monoclonal Antibody Therapy, Combination Chemotherapy, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | April 2011 | January 2014 |
NCT01205711 | Completed | Phase 2 | Irinotecan Hydrochloride, Fluorouracil, and Leucovorin Calcium With or Without Zibotentan in Treating Patients With Metastatic Colorectal Cancer | April 2010 | September 2012 |
NCT01206465 | Completed | Phase 1 | Pralatrexate and Fluorouracil in Treating Patients With Recurrent Solid Tumors | September 14, 2010 | June 1, 2017 |
NCT01212822 | Completed | Phase 2 | Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer | April 27, 2011 | January 3, 2018 |
NCT01231399 | Completed | Phase 1/Phase 2 | Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer | February 2012 | July 2016 |
NCT01249352 | Completed | Phase 2/Phase 3 | A Study of Chemoradiation Associated With Nimotuzumab as the Treatment of Locally Advanced Esophageal Cancer | January 2009 | November 2013 |
NCT01263171 | Completed | Phase 2 | Oxaliplatin, Leucovorin, and Fluorouracil Before and After Radiation Therapy and Surgery in Treating Patients With Rectal Cancer That Can Be Removed by Surgery | April 2012 | November 2015 |
NCT01333033 | Completed | Phase 2 | PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy | July 2011 | April 1, 2023 |
NCT01360086 | Completed | Phase 2 | Fluorouracil, Cisplatin, Leucovorin Calcium, and Cetuximab in Treating Patients With Adenocarcinoma of the Stomach or Gastroesophageal Junction | June 2011 | March 2013 |
NCT01383343 | Completed | Phase 1 | Sorafenib Tosylate, Bevacizumab, Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer | August 2011 | February 2017 |
NCT01413022 | Completed | Phase 1 | FOLFIRINOX Plus PF-04136309 in Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma | April 2012 | September 2016 |
NCT01467115 | Completed | Phase 2 | Induction Chemotherapy Followed by Cetuximab and Radiation Therapy for Head and Neck Cancer | March 2010 | October 7, 2014 |
NCT01498289 | Completed | Phase 2 | S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer | February 2012 | September 19, 2019 |
NCT01534637 | Completed | Phase 2 | Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer | August 2006 | August 2012 |
NCT01561014 | Completed | Phase 1 | Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction | April 2007 | March 2009 |
NCT01566435 | Completed | Phase 2 | Induction Chemotherapy With ACF Followed by Chemoradiation Therapy for Adv. Head & Neck Cancer | August 9, 2012 | October 31, 2019 |
NCT01567618 | Completed | Phase 2 | Dose-dense Biweekly Docetaxel Combined With 5-fluorouracil as First-line Treatment in Advanced Gastric Cancer | March 2012 | April 2014 |
NCT01643499 | Completed | Phase 1 | Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies | March 26, 2012 | July 2019 |
NCT01658943 | Completed | Phase 2 | Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy | August 2012 | June 2015 |
NCT01666730 | Completed | Phase 2 | Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer | February 21, 2013 | August 1, 2018 |
NCT01670721 | Completed | Phase 3 | Colorectal Cancer Metastatic | August 2012 | June 2015 |
NCT01711541 | Completed | Phase 1/Phase 2 | Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer | October 22, 2012 | May 15, 2023 |
NCT01715233 | Completed | Phase 2 | Phase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric Cancer. | December 2012 | April 2017 |
NCT01740648 | Completed | Phase 1 | Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer | November 26, 2012 | September 29, 2021 |
NCT01747551 | Completed | Phase 2 | FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer | January 2013 | July 26, 2017 |
NCT01775501 | Completed | Phase 2 | Sorafenib + mFOLFOX for Hepatocellular Carcinoma | January 2013 | December 2019 |
NCT01835041 | Completed | Phase 1 | CPI-613 and Combination Chemotherapy in Treating Patients With Metastatic Pancreatic Cancer | April 2013 | March 16, 2023 |
NCT01862003 | Completed | Phase 2 | Phase I/II Trial of Antagonism of HER in GI Cancer | May 2014 | August 2, 2019 |
NCT01893294 | Completed | Phase 1 | Gemcitabine Hydrochloride in Treating Patients With Locally Advanced Pancreatic Cancer | April 2013 | October 30, 2015 |
NCT01928290 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Advanced Stomach, Gastroesophageal, or Esophageal Cancer | November 8, 2013 | October 28, 2019 |
NCT01959672 | Completed | Phase 2 | Chemotherapy, Stereotactic Body Radiation Therapy & Nelfinavir Mesylate in Locally Advanced Pancreatic Cancer | September 6, 2013 | December 1, 2018 |
NCT02024607 | Completed | Phase 1/Phase 2 | A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer | January 2014 | November 2019 |
NCT02041481 | Completed | Phase 1 | MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer | June 2014 | January 19, 2018 |
NCT02042443 | Completed | Phase 2 | Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery | February 2014 | April 30, 2017 |
NCT02047201 | Completed | Phase 2 | Assessing Tumor Response and IMRT Treat Plan After IC Based on FDG-PET/CT for Locally Advanced HNSCC | June 2013 | January 2016 |
NCT02124148 | Completed | Phase 1 | A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer | June 18, 2014 | February 13, 2020 |
NCT02231723 | Completed | Phase 1 | A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Pancreatic Cancer | August 2014 | June 2020 |
NCT02232152 | Completed | Phase 1 | CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery | January 6, 2015 | January 11, 2023 |
NCT02244632 | Completed | Phase 1/Phase 2 | Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer | September 2014 | January 30, 2020 |
NCT02270606 | Completed | Phase 1 | Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer | December 4, 2014 | May 13, 2021 |
NCT02314117 | Completed | Phase 3 | A Study of Ramucirumab (LY3009806) in Combination With Capecitabine and Cisplatin in Participants With Stomach Cancer | January 20, 2015 | August 14, 2020 |
NCT02319018 | Completed | Phase 1 | Alisertib and Combination Chemotherapy in Treating Patients With Gastrointestinal Tumors | August 27, 2015 | September 29, 2018 |
NCT02333188 | Completed | Phase 1 | Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer | December 2014 | December 2017 |
NCT02414009 | Completed | Phase 2 | Study to Compare CAPTEM vs FOLFIRI as Second Line Treatment in Advanced, Colorectal Cancer Patients | September 2014 | July 30, 2019 |
NCT02427841 | Completed | Phase 2 | Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery | January 21, 2016 | December 12, 2022 |
NCT02562716 | Completed | Phase 2 | S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery | January 6, 2016 | September 26, 2022 |
NCT02588105 | Completed | Phase 1 | Study to Assess the Safety and Preliminary Efficacy of AZD0156 at Increasing Doses Alone or in Combination With Other Anti-cancer Treatment in Patients With Advanced Cancer | November 10, 2015 | July 26, 2022 |
NCT02620865 | Completed | Phase 1/Phase 2 | BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer | December 2015 | June 21, 2021 |
NCT02641691 | Completed | Phase 2 | Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum | May 27, 2016 | March 29, 2020 |
NCT02730546 | Completed | Phase 1/Phase 2 | Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery | June 24, 2016 | October 31, 2023 |
NCT02742051 | Completed | Phase 2 | A Trial of Neoadjuvant Everolimus Plus Letrozole Versus FEC in Women With ER-positive, HER2-negative Breast Cancer | June 2016 | March 14, 2020 |
NCT02753127 | Completed | Phase 3 | A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer | June 2016 | May 12, 2021 |
NCT02896907 | Completed | Early Phase 1 | Ascorbic Acid and Combination Chemotherapy in Treating Patients With Locally Advanced or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery | October 18, 2016 | March 2019 |
NCT02921256 | Completed | Phase 2 | Veliparib, Pembrolizumab, and Combination Chemotherapy in Treating Patient With Locally Advanced Rectal Cancer | January 11, 2017 | September 20, 2023 |
NCT03336216 | Completed | Phase 2 | A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer | December 19, 2017 | June 1, 2023 |
NCT03414983 | Completed | Phase 2/Phase 3 | An Investigational Immunotherapy Study of Nivolumab With Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Colorectal Cancer That Has Spread | February 20, 2018 | December 28, 2022 |
NCT03532711 | Completed | Potential Predictive Biomarkers in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer | January 1, 2012 | December 31, 2016 | |
NCT03617913 | Completed | Phase 2 | Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder Cancer | September 19, 2018 | July 27, 2020 |
NCT03690921 | Completed | Phase 2 | Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial | November 8, 2018 | June 3, 2022 |
NCT03748134 | Completed | Phase 3 | Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 ) | December 24, 2018 | July 29, 2023 |
NCT05178745 | Completed | A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection | September 7, 2016 | May 27, 2022 | |
NCT05009953 | Not yet recruiting | Phase 2 | Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer | September 2021 | August 2024 |
NCT04488159 | Not yet recruiting | Phase 3 | Immunoscore as Decision Guidance for Adjuvant Chemotherapy in Colon Cancer | December 1, 2024 | June 1, 2026 |
NCT05846867 | Not yet recruiting | Phase 1/Phase 2 | Study of AK119 and AK 112 With or Without Chemotherapy for Colorectal Cancer Patients | May 10, 2023 | July 10, 2025 |
NCT05047991 | Not yet recruiting | Phase 2 | Study of Irinotecan Liposome Injection-containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma | October 2021 | November 2024 |
NCT06139211 | Not yet recruiting | Phase 1/Phase 2 | A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors | November 30, 2023 | April 30, 2026 |
NCT06447662 | Not yet recruiting | Phase 1 | A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation. | July 28, 2024 | July 12, 2028 |
NCT05296005 | Not yet recruiting | Phase 1 | Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers | May 31, 2022 | December 31, 2024 |
NCT06268015 | Not yet recruiting | Phase 2 | Botensilimab and Balstilimab Optimization in Colorectal Cancer | July 2024 | July 2028 |
NCT05493332 | Not yet recruiting | Phase 2 | HAIC Combined With Donafenib Tosilate and Toripalimab for Unresectable HCC | September 2022 | September 2024 |
NCT06381154 | Not yet recruiting | Phase 2 | Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer | June 30, 2024 | July 4, 2029 |
NCT04430738 | Recruiting | Phase 1/Phase 2 | Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers | September 15, 2020 | October 31, 2025 |
NCT04762953 | Recruiting | Phase 2 | Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis | February 18, 2021 | June 2025 |
NCT05733000 | Recruiting | Phase 2 | CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors | March 8, 2023 | March 4, 2030 |
NCT04821284 | Recruiting | Phase 1/Phase 2 | Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer | December 6, 2021 | January 31, 2025 |
NCT03505320 | Recruiting | Phase 2 | A Study to Assess the Antitumor Activity, Safety, Pharmacokinetics and Biomarkers of Zolbetuximab (IMAB362) in Participants With Claudin (CLDN) 18.2 Positive, Metastatic or Advanced Unresectable Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma and Locoregional Gastric or GEJ Adenocarcinoma | June 29, 2018 | December 31, 2026 |
NCT05802056 | Recruiting | Phase 1 | Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis | November 29, 2023 | January 2026 |
NCT04329494 | Recruiting | Phase 1 | PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer | August 21, 2020 | December 30, 2025 |
NCT05836584 | Recruiting | Phase 2 | Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer | December 6, 2023 | October 31, 2027 |
NCT05843188 | Recruiting | Phase 2 | Study of Hydroxychloroquine With FOLFIRI and Bevacizumab in DTP-high Metastatic Colorectal Cancer | August 9, 2023 | October 24, 2026 |
NCT04248452 | Recruiting | Phase 3 | Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body | May 26, 2020 | March 31, 2028 |
NCT03161522 | Recruiting | Phase 2 | Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer | February 19, 2018 | December 31, 2026 |
NCT05651594 | Recruiting | Phase 2 | Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma | March 7, 2023 | March 30, 2026 |
NCT05677490 | Recruiting | Phase 3 | mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma | January 23, 2023 | November 8, 2028 |
NCT02366819 | Recruiting | Phase 4 | Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer | December 11, 2014 | June 8, 2025 |
NCT04245865 | Recruiting | Phase 2 | Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer | June 26, 2020 | October 2024 |
NCT05863195 | Recruiting | Phase 3 | Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial | October 19, 2023 | June 30, 2034 |
NCT04840264 | Recruiting | Phase 2 | Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel Obstruction | January 7, 2022 | June 30, 2027 |
NCT04927780 | Recruiting | Phase 3 | Perioperative or Adjuvant mFOLFIRINOX for Resectable Pancreatic Cancer | September 7, 2021 | July 2029 |
NCT05379595 | Recruiting | Phase 1/Phase 2 | A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer | July 29, 2022 | April 27, 2027 |
NCT05891171 | Recruiting | Phase 1 | Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers | October 13, 2023 | August 2025 |
NCT04929028 | Recruiting | Phase 2 | Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer | August 9, 2022 | September 15, 2029 |
NCT06313801 | Recruiting | Phase 2 | Comparing the Safety and Efficacy of First-line Polychemotherapy and Polychemotherapy in Combination With PIPAC Sessions | January 19, 2023 | January 19, 2026 |
NCT04539808 | Recruiting | Phase 2 | NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer | May 27, 2021 | October 5, 2025 |
NCT06011772 | Recruiting | Early Phase 1 | EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer | December 4, 2023 | December 4, 2026 |
NCT03203525 | Recruiting | Phase 1 | Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer | June 23, 2020 | December 31, 2026 |
NCT04205968 | Recruiting | Phase 2 | Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers | June 1, 2020 | June 16, 2025 |
NCT05564377 | Recruiting | Phase 2 | Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial | April 7, 2023 | July 1, 2030 |
NCT04166318 | Recruiting | Phase 2 | Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study | January 2, 2020 | December 31, 2029 |
NCT06022861 | Recruiting | Phase 3 | A Study to Compare the Efficacy and Safety of LY01015 and Opdivo® Combined Respectively With Chemotherapy in Advanced or Metastatic Esophageal Squamous Cell Carcinoma | October 12, 2023 | December 2026 |
NCT06028737 | Recruiting | Phase 2/Phase 3 | Total Neoadjuvant Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer | August 25, 2023 | December 2031 |
NCT06078709 | Recruiting | Phase 2 | Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma | November 20, 2023 | November 30, 2026 |
NCT05329766 | Recruiting | Phase 2 | A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies | June 10, 2022 | June 2027 |
NCT06094140 | Recruiting | Phase 2 | NEO-adjuvant Chemo-immunotherapy in Pancreatic Cancer | May 20, 2022 | June 2026 |
NCT05253651 | Recruiting | Phase 3 | A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer | October 24, 2022 | April 30, 2028 |
NCT06102395 | Recruiting | Phase 3 | Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC | May 1, 2023 | April 30, 2030 |
NCT06107413 | Recruiting | Phase 2 | Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab | November 12, 2023 | October 1, 2026 |
NCT01954992 | Recruiting | Phase 3 | Glufosfamide Versus 5-FU in Second Line Metastatic Pancreatic Cancer | April 2014 | December 2025 |
NCT03899155 | Recruiting | Phase 2 | Pan Tumor Rollover Study | August 9, 2019 | August 25, 2029 |
NCT05721755 | Recruiting | Phase 3 | Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck | June 8, 2023 | March 31, 2030 |
NCT02997228 | Recruiting | Phase 3 | Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer, the COMMIT Study | January 19, 2018 | November 30, 2024 |
NCT04745988 | Recruiting | Phase 2 | An Open Label Phase 2 Study to Evaluate the Safety and Efficacy of Lenvatinib With Pembrolizumab or Lenvatinib, Pembrolizumab and FLOT in the Neoadjuvant / Adjuvant Treatment for Patients With Gastric Cancer | November 11, 2021 | August 2027 |
NCT05727163 | Recruiting | Phase 2 | FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients | July 29, 2022 | December 31, 2026 |
NCT06280495 | Recruiting | Phase 2/Phase 3 | Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients | February 1, 2024 | December 31, 2028 |
NCT04340141 | Recruiting | Phase 3 | Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer | July 1, 2020 | November 2030 |
NCT04615013 | Recruiting | Phase 1 | NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer | November 23, 2020 | October 31, 2025 |
NCT05627635 | Recruiting | Phase 1/Phase 2 | FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer | May 3, 2023 | April 1, 2025 |
NCT03784326 | Recruiting | Phase 2 | Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma | February 19, 2019 | December 31, 2024 |
NCT03800693 | Recruiting | Phase 2 | 2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers | March 14, 2019 | November 4, 2024 |
NCT04008030 | Recruiting | Phase 3 | A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC) | August 5, 2019 | June 10, 2026 |
NCT04703101 | Recruiting | Phase 1 | Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer | February 11, 2021 | October 15, 2026 |
NCT04668976 | Recruiting | Phase 2 | A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma | November 25, 2020 | December 2024 |
NCT06417476 | Recruiting | Phase 2 | Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer | December 12, 2022 | December 2025 |
NCT05482893 | Recruiting | Phase 1/Phase 2 | PT886 For Treatment of Patients With Metastatic/Advanced Gastric, Gastroesophageal Junction and Pancreatic Adenocarcinoma (the TWINPEAK Study) | March 15, 2023 | April 2026 |
NCT06269978 | Recruiting | Phase 1 | Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer | June 30, 2024 | December 31, 2025 |
NCT05564403 | Recruiting | Phase 2 | Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial) | February 9, 2024 | January 21, 2025 |
NCT03073785 | Recruiting | Phase 2 | Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer | September 16, 2016 | December 2027 |
NCT06441565 | Recruiting | Phase 2/Phase 3 | Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer | May 24, 2024 | December 30, 2029 |
NCT05567835 | Recruiting | Phase 2 | A Study of Total Neoadjuvant Chemotherapy With FLOT VS Standard Perioperative FLOT in Patients With Gastric or GEJ Cancer | March 6, 2024 | January 2029 |
NCT05699603 | Recruiting | Phase 2 | Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients | August 18, 2024 | February 1, 2029 |
NCT04354662 | Recruiting | Phase 2 | Toripalimab Combined With FLOT Neoadjuvant Chemotherapy in Patients With Resectable Gastric Cancer | September 26, 2019 | June 30, 2024 |
NCT04005339 | Recruiting | Phase 2 | NAPOLI-2: Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Biliary Cancer | July 29, 2019 | July 31, 2024 |
NCT05688215 | Suspended | Phase 1/Phase 2 | Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma | March 7, 2023 | May 1, 2026 |
NCT00002696 | Suspended | Phase 3 | Combination Chemotherapy in Treating Women With Stage III Breast Cancer | October 1995 | |
NCT02897050 | Suspended | Phase 2 | Trial of Neoadjuvant Docetaxel ± Metronomic Capecitabine/CTX Followed by FEC in Women With Operable Triple Negative Breast Cancer | September 2016 | September 2024 |
NCT04380545 | Suspended | Phase 1/Phase 2 | Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer | January 13, 2021 | July 31, 2025 |
NCT00303628 | Terminated | Phase 3 | Postoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal Cancer | May 11, 2006 | February 11, 2019 |
NCT00006015 | Terminated | Phase 2 | Combination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal Cancer | May 2000 | February 2003 |
NCT00005944 | Terminated | Phase 2 | Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer | July 1, 1999 | October 1, 2003 |
NCT00002525 | Terminated | Phase 3 | Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed | October 1, 1993 | April 2015 |
NCT00044785 | Terminated | Phase 1 | Phase I Study of PN401, Fluorouracil, Leucovorin and CPT-11 in Patients With Solid Tumors | August 2002 | March 2004 |
NCT03009058 | Terminated | Phase 1/Phase 2 | Study of IMM 101 in Combination With Standard of Care in Patients With Metastatic or Unresectable Cancer | May 24, 2017 | August 30, 2017 |
NCT00720512 | Terminated | Phase 3 | Second-Line Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer Who Have Received First-Line Chemotherapy and Bevacizumab | June 2008 | March 2014 |
NCT00352118 | Terminated | Phase 2 | Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer | March 2006 | April 2008 |
NCT01779050 | Terminated | Phase 2 | Effect of Trastuzumab on Disease Free Survival in Early Stage HER2-Negative Breast Cancer Patients With ERBB2 Expressing Disseminated Tumor Cells | December 19, 2013 | September 1, 2021 |
NCT01229111 | Terminated | Phase 2 | Cediranib Maleate and Combination Chemotherapy in Treating Patients With Advanced Biliary Cancers | October 2010 | March 2014 |
NCT03300544 | Terminated | Phase 1 | Talimogene Laherparepvec, Chemotherapy, and Radiation Therapy Before Surgery in Treating Patients With Locally Advanced or Metastatic Rectal Cancer | May 14, 2019 | March 22, 2022 |
NCT03300609 | Terminated | Phase 3 | 5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab | February 27, 2018 | October 3, 2019 |
NCT01238965 | Terminated | Phase 1 | Panobinostat and Fluorouracil Followed By Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer Who Did Not Respond to Previous Fluorouracil-Based Chemotherapy | October 2010 | April 2015 |
NCT00043004 | Terminated | Phase 2 | Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer | May 2002 | |
NCT01897454 | Terminated | Phase 2 | Gemcitabine Hydrochloride, and Radiation Therapy in Patients With Borderline Resectable Pancreatic Cancer | January 27, 2012 | November 1, 2021 |
NCT00004897 | Terminated | Phase 2 | Combination Chemotherapy and Interferon Alfa Followed by Surgery and/or Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer | October 1999 | November 2007 |
NCT03387098 | Terminated | Phase 1/Phase 2 | QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy | December 28, 2017 | January 15, 2019 |
NCT02017600 | Terminated | Phase 2 | A Phase II Trial of Induction Chemotherapy With ND-420, Cisplatin and Fluorouracil Followed by Surgery in the Treatment of Patients With Localized Squamous Cell Carcinoma of the Esophagus | August 2013 | April 4, 2015 |
NCT00499369 | Terminated | Phase 3 | Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy | June 2007 | November 2012 |
NCT00524186 | Terminated | Phase 1 | Sunitinib, Irinotecan, Fluorouracil, and Leucovorin In Treating Patients With Advanced Stomach Cancer or Gastroesophageal Cancer | May 2007 | April 2016 |
NCT00537823 | Terminated | Phase 2 | Pre- and Post-operative FOLFOX Based Therapy for Patients With Colorectal Cancer With Liver Involvement | June 2007 | July 2011 |
NCT00541112 | Terminated | Phase 2 | Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery | October 29, 2007 | January 29, 2010 |
NCT00004099 | Terminated | Phase 3 | Surgery With or Without Combination Chemotherapy in Treating Patients With Stomach Cancer | July 1999 | |
NCT01279681 | Terminated | Phase 3 | Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer | January 2011 | November 1, 2014 |
NCT01280643 | Terminated | N/A | Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | March 2010 | May 2014 |
NCT00053911 | Terminated | Phase 3 | Combination Chemotherapy Compared With Observation After Surgery in Treating Women With Relapsed Nonmetastatic Breast Cancer | November 2002 | |
NCT01307956 | Terminated | Phase 2 | Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer | February 28, 2011 | December 23, 2015 |
NCT01320683 | Terminated | Phase 2 | Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer | March 2011 | December 2014 |
NCT00646659 | Terminated | Phase 2 | Cetuximab, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Head and Neck Cancer That Cannot Be Removed By Surgery | February 2008 | April 2011 |
NCT00030511 | Terminated | Phase 2 | Radiation Therapy and Fluorouracil Before Surgery in Treating Patients With Primary or Recurrent Bile Duct Cancer | October 2001 | |
NCT01197664 | Terminated | Phase 1 | Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery | August 2010 | April 2014 |
NCT00003777 | Terminated | Phase 2 | Surgery, Radiation Therapy, and Combination Chemotherapy in Treating Patients With Recurrent Head and Neck Cancer | December 1998 | April 20, 2001 |
NCT00602329 | Terminated | Phase 2 | MRI in Predicting Response in Patients Receiving Combination Chemotherapy and Bevacizumab For Advanced or Metastatic Colorectal Cancer | February 2006 | October 2009 |
NCT00064259 | Terminated | Phase 1/Phase 2 | A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer | June 2003 | February 2010 |
NCT00609765 | Terminated | Phase 2 | Avastin, Fluorouracil, Doxorubicin and Streptozocin in Locally Advanced and Metastatic Pancreatic Endocrine Tumors | August 2007 | March 2008 |
NCT00003642 | Terminated | Phase 2 | Radiation Therapy and Chemotherapy Following Surgery in Treating Patients With Stage II or Stage III Bladder Cancer | October 1998 | |
NCT01198548 | Terminated | Phase 2 | High-Dose Cholecalciferol in Treating Patients Receiving Combination Chemotherapy and Bevacizumab as First-Line Therapy For Metastatic Colorectal Cancer | August 2010 | June 2012 |
NCT01375816 | Terminated | Phase 2 | Liposome-encapsulated Irinotecan Hydrochloride PEP02 or Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil as Second-Line Therapy in Treating Patients With Metastatic Colorectal Cancer | May 2011 | December 2014 |
NCT03878524 | Terminated | Phase 1 | Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial | April 1, 2020 | December 10, 2020 |
NCT00642746 | Terminated | Phase 2 | Erlotinib and Chemotherapy for 2nd Line Treatment (Tx) of Metastatic Colorectal Cancer (mCRC) | March 2008 | December 2011 |
NCT00068744 | Terminated | Phase 2/Phase 3 | Radiation Therapy, Mitomycin, and Either Fluorouracil or Cisplatin in Treating Patients With Locally Advanced Anal Cancer | July 2003 | |
NCT00070122 | Terminated | Phase 3 | Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Colorectal Cancer | April 2004 | |
NCT00955240 | Terminated | Phase 2 | Radiation Therapy, Cisplatin, Fluorouracil, and Cetuximab in Treating Patients With Locally Advanced Anal Cancer | March 2009 | November 26, 2010 |
NCT00002735 | Terminated | Phase 2 | SWOG-9451, Combination Chemo & RT For Patients With Stage III/Stage IV Cancer of the Hypopharynx or Tongue | April 1996 | March 2005 |
NCT00002796 | Terminated | Phase 1/Phase 2 | Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer | May 1997 | |
NCT00006472 | Terminated | Phase 2 | Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer | January 2000 | September 10, 2002 |
NCT02345460 | Terminated | Phase 2 | Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study | September 2015 | March 2016 |
NCT01479465 | Terminated | Phase 2 | Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma | December 2011 | February 2015 |
NCT01123473 | Terminated | Phase 2 | Epirubicin Hydrochloride, Cisplatin, and Fluorouracil or Capecitabine With or Without Lapatinib Ditosylate as First-Line Therapy in Treating Patients With Stomach Cancer or Gastroesophageal Junction Cancer | December 2010 | September 2014 |
NCT02392377 | Terminated | Phase 2 | Molecular Phenotyping in Predicting Response in Patients With Stage IB-III Esophageal Cancer Receiving Combination Chemotherapy | February 2015 | December 2015 |
NCT00103103 | Terminated | Phase 2 | Bortezomib, Fluorouracil, and Leucovorin in Treating Patients With Metastatic or Unresectable Stomach Cancer | March 2005 | August 2005 |
NCT00113399 | Terminated | Phase 3 | Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery | April 2005 | |
NCT02508077 | Terminated | Phase 2 | FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer | February 16, 2016 | September 13, 2017 |
NCT00023868 | Terminated | Phase 3 | Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655) | November 1, 2001 | September 25, 2002 |
NCT00052585 | Terminated | Phase 2 | Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer | October 2002 | |
NCT00262951 | Terminated | Phase 2 | Chemoradiation in Locally Advanced Pancreatic Cancer | January 2005 | August 2011 |
NCT00766142 | Terminated | Phase 2 | Chemotherapy and Cetuximab in Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer | May 1, 2007 | September 17, 2013 |
NCT00003086 | Terminated | Phase 1/Phase 2 | Repeated Bone Marrow Transplantation in Treating Women With Advanced Breast Cancer | March 1997 | January 28, 2001 |
NCT00006037 | Terminated | Phase 2 | Chemotherapy Plus IM-862 in Treating Patients With Metastatic Colorectal Cancer | November 1999 | November 2001 |
NCT01093235 | Unknown status | Phase 3 | Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer | April 2009 | |
NCT00016042 | Unknown status | Phase 1 | Fluorouracil and Biological Therapy in Treating Patients With Metastatic Kidney or Colorectal Cancer | January 2001 | |
NCT00002884 | Unknown status | Phase 3 | Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus | March 1996 | |
NCT01167725 | Unknown status | Phase 3 | Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer | August 2010 | |
NCT00002793 | Unknown status | Phase 3 | Chemotherapy Via an Implantable Pump Compared With a Subcutaneous Port for Unresectable Liver Metastases in Patients With Resected Colorectal Cancer | January 1991 | |
NCT01211210 | Unknown status | Phase 2/Phase 3 | Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal Cancer | June 2010 | June 2020 |
NCT00002747 | Unknown status | Phase 3 | Surgery and Radiation Therapy With or Without Chemotherapy in Treating Patients With Mouth Cancer | September 1992 | |
NCT04755543 | Unknown status | Phase 1 | A Study of LP002 for the Treatment of Patients With Malignant Digestive System Neoplasms | June 17, 2019 | June 30, 2022 |
NCT01391572 | Unknown status | Phase 2 | A Trial Estimating The Optimal Radiation Volume Of Postsurgical Radiation For Patients With Esophageal Cancer | April 2011 | |
NCT01494363 | Unknown status | Phase 2 | Phase II Study of FOLFOXIRI in Patients With Locally Advanced or Metastatic Biliary Tract Cancer | October 2011 | December 2013 |
NCT00002692 | Unknown status | Phase 3 | Intravenous Compared With Intrahepatic Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver | December 1994 | |
NCT01652196 | Unknown status | Phase 2 | Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer | November 14, 2012 | December 31, 2019 |
NCT01814501 | Unknown status | Phase 2 | Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab | February 1, 2013 | December 31, 2019 |
NCT00012311 | Unknown status | Phase 2 | Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Chemotherapy Alone in Treating Women With Stage IV Breast Cancer | January 2000 | |
NCT00010088 | Unknown status | Phase 2 | Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas or Bile Duct | January 1999 | |
NCT01880385 | Unknown status | Phase 1 | Efficacy and Safety of Bevacizumab in the Neodjuvant Treatment of Inflammatory Breast Cancer | March 2011 | April 2017 |
NCT00002498 | Unknown status | Phase 2 | Combination Chemotherapy Compared With Mitoxantrone in Treating Older Patients With Advanced Breast Cancer | July 1992 | |
NCT02021422 | Unknown status | Phase 1 | A Pilot, Prospective, Non-randomized Evaluation of the Safety of Anakinra Plus Standard Chemotherapy | June 2013 | December 2017 |
NCT00010075 | Unknown status | Phase 2 | Combination Chemotherapy in Treating Older Women With Metastatic Breast Cancer | January 2000 | |
NCT00010062 | Unknown status | Phase 2 | Fluorouracil Plus Radiation Therapy Following Surgery in Treating Patients With Pancreatic Cancer | October 2000 | |
NCT00058474 | Unknown status | Phase 3 | Radiation Therapy and Either Capecitabine or Fluorouracil With or Without Oxaliplatin Before Surgery in Treating Patients With Resectable Rectal Cancer | July 2004 | May 2016 |
NCT00008281 | Unknown status | Phase 3 | Comparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer | October 2000 | |
NCT02071069 | Unknown status | Phase 2 | Efficacy and Tolerance of Maintenance Therapy in Patients With Incurable Advanced Colorectal Cancer | July 2013 | July 2016 |
NCT02115152 | Unknown status | Phase 2 | Neoadjuvant Trial of Capecitabine for Axillary Lymph Node Positive Operable Breast Cancer | June 2014 | |
NCT00008047 | Unknown status | Phase 1/Phase 2 | Combination Chemotherapy Combined With Radiation Therapy in Treating Patients Who Have Stage II or Stage III Cancer of the Esophagus | August 1999 | |
NCT00006479 | Unknown status | Phase 3 | Surgery With or Without Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer | September 2000 | |
NCT00072553 | Unknown status | Phase 2 | Celecoxib, Leucovorin, Fluorouracil, and Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer | September 2003 | |
NCT00075595 | Unknown status | Phase 2 | Fluorouracil, Leucovorin, and Irinotecan in Treating Patients With Recurrent or Refractory Metastatic Unresectable Colorectal Cancer | June 2002 | |
NCT00075738 | Unknown status | Phase 2 | Fluorouracil, Irinotecan, Leucovorin, and Cisplatin as First-Line Therapy in Treating Patients With Metastatic Esophageal Cancer | October 2003 | |
NCT00079365 | Unknown status | N/A | Fluorouracil, External-Beam Radiation Therapy, and Gemcitabine With or Without Brachytherapy Using Phosphorus P32 in Treating Patients With Locally or Regionally Advanced Unresectable Adenocarcinoma of the Pancreas | May 2001 | |
NCT02325986 | Unknown status | Phase 2 | Concurrent Radiotherapy and Weekly Chemotherapy of PF for Postoperative Locoregional Recurrence of Esophageal Cancer | March 2015 | December 2017 |
NCT00091312 | Unknown status | Phase 3 | Fluorouracil and Irinotecan With or Without Leucovorin Compared With Observation in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer | June 2004 | |
NCT00093665 | Unknown status | Phase 2 | Fluorouracil, Cisplatin, and Radiation Therapy in Treating Patients With Stage II, Stage III, or Stage IV Nasopharyngeal Cancer | November 2003 | |
NCT02415699 | Unknown status | Phase 2/Phase 3 | DC-CIK Immunotherapy Plus Chemotherapy vs Chemotherapy Alone in the Adjuvant Treatment of Stage III Colorectal Cancer | August 2015 | July 2020 |
NCT00006468 | Unknown status | Phase 3 | Comparing Two Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer | January 2000 | |
NCT00006115 | Unknown status | Phase 2 | Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer | April 1999 | |
NCT02500940 | Unknown status | Phase 3 | Comparison the Effects of Different Neoadjuvant Chemotherapy Regimen on Acute Toxicity, Tumor Response, and Survival in Patients With Advanced Nasopharyngeal Carcinoma | May 2015 | May 2021 |
NCT02506842 | Unknown status | Phase 3 | Second-Line Adjuvant Therapy With Nab-Paclitaxel Plus Gemcitabine Versus Oxaliplatin Plus Folinic Acid and Fluorouracil for Gemcitabine-Refractory Pancreatic Cancer After Curative Resection | June 2015 | June 2019 |
NCT02515734 | Unknown status | Phase 2 | A Study of FOLFOXIRI Plus Cetuximab vs. FOLFOXIRI Plus Bevacizumab | August 2015 | June 2020 |
NCT00006112 | Unknown status | Phase 2 | Fluorouracil With or Without Mitomycin in Treating Patients With Peritoneal Cancer | January 1996 | |
NCT00182715 | Unknown status | Phase 3 | Combination Chemotherapy With or Without Cetuximab as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer | March 2005 | |
NCT00274872 | Unknown status | Phase 2/Phase 3 | Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery | January 2004 | |
NCT00275119 | Unknown status | Phase 2 | Gemcitabine and Oxaliplatin Followed By Radiation Therapy, Fluorouracil, and Oxaliplatin in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery | November 2003 | |
NCT00046995 | Unknown status | Phase 3 | Combination Chemotherapy in Treating Patients With Colon Cancer | May 2001 | |
NCT00309920 | Unknown status | N/A | Combination Chemotherapy With or Without Darbepoetin Alfa in Treating Women With Stage III Breast Cancer | January 2004 | |
NCT02969473 | Unknown status | Phase 2 | Definitive Concurrent Chemoradiotherapy With Docetaxel Plus Cisplatin Versus 5-fluorouracil Plus Cisplatin in Patients With Esophageal Squamous Cell Carcinoma | October 2010 | May 2017 |
NCT03002064 | Unknown status | Phase 3 | Docetaxol Plus Cisplatin Versus 5-Fu Plus Cisplatin as 1st-line Chemotherapy in Advanced ESCC Patients | December 2016 | December 2020 |
NCT03045770 | Unknown status | N/A | mFOLFOX Versus mFOLFIRI Versus FOLFPTX as First-line Treatment in AGC or EGJA | February 10, 2017 | December 30, 2019 |
NCT00408551 | Unknown status | Phase 2 | Chemotherapy and Internal Radiation in Treating Patients With Colorectal Cancer That Has Spread to the Liver | November 2005 | |
NCT00005871 | Unknown status | Phase 3 | Nitrocamptothecin or Fluorouracil in Treating Patients With Recurrent or Refractory Pancreatic Cancer | November 1998 | |
NCT03167112 | Unknown status | Phase 2 | A Study of Administering FOLFIRINOX Before Surgery For Potentially Curable Pancreatic Cancer | July 3, 2017 | May 2018 |
NCT00005870 | Unknown status | Phase 3 | Nitrocamptothecin Compared With Other Chemotherapy in Treating Patients With Recurrent or Refractory Cancer of the Pancreas | March 1999 | |
NCT03221400 | Unknown status | Phase 1/Phase 2 | PEN-866 in Patients With Advanced Solid Malignancies | August 29, 2017 | June 2023 |
NCT00425425 | Unknown status | Phase 1/Phase 2 | Cetuximab, Oxaliplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Esophageal Cancer | July 2006 | May 2015 |
NCT00005607 | Unknown status | Phase 2 | Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Cancer of the Stomach or Esophagus | February 2000 | |
NCT00005581 | Unknown status | Phase 3 | Combination Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer | June 2000 | |
NCT00436267 | Unknown status | Phase 2 | Internal Radiation Therapy With Y-90 Microspheres, External Radiation Therapy With Tomotherapy, and Fluorouracil in Treating Patients With Newly Diagnosed or Recurrent Pancreatic Cancer and Liver Metastases That Cannot Be Removed By Surgery | November 2006 | |
NCT00438737 | Unknown status | Phase 2 | Cetuximab, Leucovorin, Oxaliplatin, and Fluorouracil With or Without Bevacizumab in Treating Patients With Resectable Liver Metastases From Colorectal Cancer | January 2007 | |
NCT03349177 | Unknown status | Phase 2/Phase 3 | Pathological Complete Response Rate in Locally Advanced Breast Cancer With FEC, EC-T, or TC as Neoadjuvant Chemotherapy | November 27, 2017 | November 27, 2019 |
NCT00004206 | Unknown status | Phase 2 | Oxaliplatin and Fluorouracil in Treating Patients With Recurrent Ovarian Cancer | September 1999 | |
NCT00471484 | Unknown status | Phase 2 | Combination Chemotherapy and Interferon Alfa-2b in Treating Patients With Nonmetastatic Liver Cancer That Cannot Be Removed by Surgery | March 2007 | |
NCT00482222 | Unknown status | Phase 3 | Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer | February 2007 | |
NCT00041262 | Unknown status | Phase 3 | Combination Chemotherapy in Treating Patients With Esophageal Cancer | November 2004 | |
NCT00004164 | Unknown status | Phase 2 | Combination Chemotherapy in Treating Patients With Stage IIB, Stage III, or Stage IV Cancer of the Nasopharynx | August 1999 | |
NCT00513266 | Unknown status | Phase 2 | Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer With Liver Metastases or Lung Metastases That Are Potentially Removable by Surgery | June 2007 | |
NCT00533936 | Unknown status | Phase 2 | Trastuzumab or Observation After Combination Chemotherapy and Trastuzumab in Treating Patients Undergoing Surgery for Stage II or Stage III Breast Cancer | September 2006 | |
NCT03522649 | Unknown status | Phase 3 | A Phase III Clinical Study of Napabucasin (GB201) Plus FOLFIRI in Adult Patients With Metastatic Colorectal Cancer | April 12, 2018 | November 2021 |
NCT00544011 | Unknown status | Phase 2 | Bevacizumab and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer | April 2007 | |
NCT03579004 | Unknown status | Phase 2 | Neoadjuvant Chemotherapy Followed by Preoperative Chemoradiation in Resectable Squamous-cell Esophageal Cancer | July 10, 2017 | July 10, 2020 |
NCT00033683 | Unknown status | Phase 2 | Combination Chemotherapy in Treating Women With Resected Breast Cancer | February 2001 | |
NCT00004097 | Unknown status | Phase 1 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced and/or Recurrent Head and Neck Cancer | August 1999 | |
NCT03668418 | Unknown status | Xenotransplantation of Primary Cancer Samples in Zebrafish Embryos | June 1, 2018 | May 31, 2022 | |
NCT00004094 | Unknown status | Phase 2 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Advanced Cancer of the Mouth, Pharynx, or Larynx | August 1999 | |
NCT03732508 | Unknown status | Phase 2 | SHR-1316 in Combination With Chemotherapy in Patients With Esophageal Squamous Cell Cancer | November 2018 | October 2020 |
NCT00003680 | Unknown status | Phase 3 | Standard Chemotherapy Compared With High-Dose Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Women With Advanced or Inflammatory Breast Cancer | November 1998 | |
NCT00003664 | Unknown status | Phase 2 | Combination Chemotherapy and Biological Therapy In Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed Surgically | October 1998 | |
NCT00629278 | Unknown status | Phase 3 | Combination Chemotherapy and Trastuzumab in Treating Women With Stage I, Stage II, or Stage III HER2-Positive Breast Cancer | December 2007 | |
NCT00003637 | Unknown status | Phase 3 | Radiation Therapy Alone Compared to Radiation Therapy Plus Chemotherapy in Treating Patients With Previously Untreated Cancer of the Nasopharynx | September 1998 | |
NCT03910634 | Unknown status | Phase 2 | IMRT With Carboplatin Versus IMRT With Carboplatin and Fluorouracil for Eldly Esophageal Cancer Patients | April 9, 2019 | December 31, 2021 |
NCT00647530 | Unknown status | Phase 2/Phase 3 | Fluorouracil and Oxaliplatin With or Without Panitumumab In Treating Patients With High-Risk Colon Cancer That Can Be Removed by Surgery | May 15, 2008 | December 31, 2019 |
NCT03925233 | Unknown status | Breast Cancer Treatment Based on Organ-like Culture | January 2, 2019 | December 15, 2021 | |
NCT00003558 | Unknown status | Phase 3 | Chemotherapy in Treating Patients With Cancer of Unknown Primary Origin | August 1998 | |
NCT00027833 | Unknown status | Phase 2 | Vaccine Therapy and Chemotherapy With or Without Tetanus Toxoid Compared With Chemotherapy Alone in Treating Patients With Metastatic Colorectal Cancer | December 2001 | |
NCT00003260 | Unknown status | Phase 3 | Combination Chemotherapy in Treating Patients With Recurrent Metastatic Colorectal Cancer | January 1998 | |
NCT00003135 | Unknown status | Phase 2 | Whole Body Hyperthermia Combined With Chemotherapy in Treating Patients With Metastatic Breast, Ovarian, Endometrial, or Cervical Cancer | November 1997 | |
NCT00766480 | Unknown status | N/A | Study of Tissue Samples in Predicting How Well Chemotherapy and Radiation Therapy Will Kill Cancer Cells in Patients With Squamous Cell Carcinoma of the Esophagus | January 2007 | |
NCT00003063 | Unknown status | Phase 3 | Biological Therapy With Combination Chemotherapy in Patients With Colorectal Cancer | November 1991 | |
NCT00797485 | Unknown status | Phase 3 | Bevacizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Metastatic Colorectal Cancer That Cannot Be Removed By Surgery | July 2008 | |
NCT00884767 | Unknown status | Phase 2 | Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin | September 2007 | |
NCT00003001 | Unknown status | Phase 1/Phase 2 | Combination Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer | April 1997 | |
NCT00002896 | Unknown status | Phase 3 | Radiation Therapy Plus Chemotherapy Before Surgery With or Without Chemotherapy After Surgery in Treating Patients With Rectal Cancer | September 1993 | |
NCT00022178 | Unknown status | Phase 3 | Combination Chemotherapy in Treating Patients With Metastatic Cancer of an Unknown Site of Origin | December 1998 | |
NCT00021281 | Unknown status | Phase 3 | Combination Chemotherapy With or Without SU5416 in Treating Patients With Metastatic Colorectal Cancer | December 2000 | |
NCT01031030 | Unknown status | Phase 3 | Cyclophosphamide, Methotrexate, and Fluorouracil, With or Without Epirubicin Hydrochloride, in Treating Women Who Have Undergone Surgery for Breast Cancer (Group III Closed to New Patients as of 12/7/2009) | November 1997 | |
NCT00002893 | Unknown status | Phase 3 | Palliative Chemotherapy in Treating Patients With Advanced Colorectal Cancer | June 1995 | |
NCT02575508 | Withdrawn | Phase 1/Phase 2 | Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer | ||
NCT02573220 | Withdrawn | Phase 1 | Irinotecan Hydrochloride With FOLFIRI and Cetuximab as First-Line Therapy in Treating Patients With RAS Wild-Type Colorectal Cancer | June 2015 | August 2016 |
NCT01270438 | Withdrawn | Phase 2 | Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colorectal Cancer | December 2010 | August 2013 |
NCT01142414 | Withdrawn | Phase 3 | Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients Who Have Undergone Surgery for Advanced Hypopharyngeal Cancer, Oropharyngeal Cancer, Laryngeal Cancer, or Oral Cavity Cancer at High Risk of Recurrence | ||
NCT00002999 | Withdrawn | Phase 2 | S9715, Chemotherapy and Radiation Therapy in Treating Patients With Advanced Cancer of the Nasopharynx | ||
NCT00936832 | Withdrawn | Phase 2 | Sunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Rectal Cancer That Cannot Be Removed by Surgery | April 2009 | March 24, 2010 |
NCT00571740 | Withdrawn | Phase 2 | Cetuximab and Bevacizumab as First-Line Therapy Followed By Combination Chemotherapy and Bevacizumab With or Without Cetuximab as Second-Line Therapy in Treating Patients With Stage IV Colorectal Cancer | ||
NCT02413853 | Withdrawn | Phase 2 | Combination Chemotherapy and Bevacizumab With or Without PRI-724 in Treating Patients With Newly Diagnosed Metastatic Colorectal Cancer | November 2015 | November 2018 |
NCT02344810 | Withdrawn | Phase 1/Phase 2 | C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer | March 6, 2015 | |
NCT02296671 | Withdrawn | Phase 2 | Personalized Therapy for Esophagogastric Cancer Using Thymidylate Synthase Genetic Markers | February 2015 | February 2022 |
NCT00070434 | Withdrawn | Phase 2 | S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum | August 2004 | |
NCT02235324 | Withdrawn | Phase 2 | Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer | March 2015 | March 2018 |
NCT03386838 | Withdrawn | Phase 3 | An Immuno-therapy Study of Nivolumab in Combination With Experimental Medication BMS-986205 Compared to Standard of Care EXTREME Regimen in First-line Recurrent/Metastatic Squamous Cell Carcinoma of Head and Neck | March 28, 2018 | April 19, 2018 |
NCT03110510 | Withdrawn | Phase 2 | FOLFIRI as Salvage Treatment in Metastatic Biliary Tract Cancer (BTC) Patients Who Were Failed After Gemcitabine Containing Chemotherapy: A Phase II Single Arm Prospective Study | September 6, 2019 | September 6, 2019 |
NCT03069950 | Withdrawn | Phase 2 | Study of Chemotherapy With or Without Hepatic Arterial Infusion for Patients With Unresectable Metastatic Colorectal Cancer to the Liver | February 28, 2017 | May 16, 2019 |
NCT01941173 | Withdrawn | N/A | Short-Infusion Ziv-aflibercept in Treating Patients With Metastatic Colorectal Cancer Receiving Combination Chemotherapy | January 2014 | |
NCT02856867 | Withdrawn | Phase 2 | Nintedanib Plus mFOLFOX6 for Previously Untreated Metastatic Esophagogastric Adenocarcinoma (MEGAN) | December 2016 | |
NCT00006106 | Withdrawn | Phase 1 | ONYX-015 With Cisplatin and Fluorouracil in Treating Patients With Advanced Head and Neck Cancer | July 1999 | |
NCT04480190 | Withdrawn | Phase 1 | Neoadjuvant Therapy in Biliary Adenocarcinoma | February 4, 2021 | April 4, 2022 |
NCT01473303 | Withdrawn | Phase 1/Phase 2 | Combination Chemotherapy With or Without Ganitumab in Treating Patients With Previously Untreated Metastatic Pancreatic Cancer | August 2012 | |
NCT01159236 | Withdrawn | N/A | Molecular Triaging of Newly Diagnosed Breast Cancer | September 2010 | |
NCT00238160 | Withdrawn | Phase 3 | Surgery With or Without Hepatic Arterial Chemotherapy in Treating Patients With Liver Cancer |