chr3:9757089:C>G Detail (hg38) (OGG1)

Information

Genome

Assembly Position
hg19 chr3:9,798,773-9,798,773 View the variant detail on this assembly version.
hg38 chr3:9,757,089-9,757,089

HGVS

Type Transcript Protein
RefSeq NM_002542.5:c.994C>G NP_002533.1:p.Pro332Ala
NM_016820.3:c.994C>G NP_058213.1:p.Pro332Ala
NM_016828.2:c.948+273C>G
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

JP HGVD:0.475
ToMMo:0.460
NCBN:[No Data.]
NCBN(Hondo):[No Data.]
NCBN(Ryukyu):[No Data.]
East asia ExAC:0.588

Prediction

ClinVar

Clinical Significance Benign
Review star
Show details
Links
Type Database ID Link
Gene MIM 601982 OMIM
HGNC 8125 HGNC
Ensembl ENSG00000114026 Ensembl
NCBI NCBI
Gene Cards Gene Cards
OncoKB OncoKB
Type Database ID Link
Variant TogoVar tgv11422628 TogoVar
COSMIC
MONDO
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance Last evaluated Review status Condition Origin Links
Benign 2019-10-17 criteria provided, single submitter OGG1-related disorder germline Detail
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 Stage IV Prostate Cancer AJCC v7 Seven interactions were statistically significant after adjusting for multiple t... BeFree 25315963 Detail
<0.001 Stage IV Prostate Cancer AJCC v7 Seven interactions were statistically significant after adjusting for multiple t... BeFree 25315963 Detail
<0.001 Stage IV Prostate Cancer AJCC v7 Seven interactions were statistically significant after adjusting for multiple t... BeFree 25315963 Detail
<0.001 Stage IV Prostate Carcinoma Seven interactions were statistically significant after adjusting for multiple t... BeFree 25315963 Detail
<0.001 Stage IV Prostate Carcinoma Seven interactions were statistically significant after adjusting for multiple t... BeFree 25315963 Detail
<0.001 Stage IV Prostate Carcinoma Seven interactions were statistically significant after adjusting for multiple t... BeFree 25315963 Detail
0.001 Diabetes (i) to determine the extent of oxidative stress and DNA damage and repair using ... BeFree 21338322 Detail
0.131 diabetes mellitus (i) to determine the extent of oxidative stress and DNA damage and repair using ... BeFree 21338322 Detail
0.006 colorectal carcinoma Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-a... BeFree 21695387 Detail
0.144 Diabetes Mellitus, Non-Insulin-Dependent According to our study results, it has been observed that the combined evaluatio... BeFree 22652274 Detail
0.072 Malignant neoplasm of lung Association between the hOGG1 Ser326Cys polymorphism and lung cancer susceptibil... BeFree 23971971 Detail
0.013 Carcinoma of lung The association of OGG1 Ser326Cys polymorphism and urinary 8-OHdG levels with lu... BeFree 19064361 Detail
0.013 Malignant neoplasm of stomach Lack of association between the hOGG1 Ser326Cys polymorphism and gastric cancer ... BeFree 22799296 Detail
0.072 Malignant neoplasm of lung In a nested case-cohort design we examined associations between urinary excretio... BeFree 22044660 Detail
0.019 squamous cell carcinoma Protective association exhibited by the single nucleotide polymorphism (SNP) rs1... BeFree 21727658 Detail
0.004 Carcinoma of bladder hOGG1 Ser326Cys polymorphism is associated with risk of bladder cancer in a Chin... BeFree 22463382 Detail
0.005 breast carcinoma The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis. BeFree 20058067 Detail
0.203 renal cell carcinoma hOGG1 Ser326Cys polymorphism and renal cell carcinoma risk in a Chinese populati... BeFree 21166493 Detail
0.008 Cerebrovascular accident Moreover, among smokers carrying the OGG1 Ser326Cys polymorphism, there was a te... BeFree 22277767 Detail
0.001 uterine corpus cancer The hOGG1 Ser326Cys may not play an important role in susceptibility to endometr... BeFree 21866464 Detail
0.010 colorectal carcinoma In the present study, we investigated the role in colorectal cancer of single-nu... BeFree 18006925 Detail
<0.001 Hyperkeratosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.004 Carcinoma of bladder Lack of association between hOGG1 Ser326Cys polymorphism and the risk of bladder... BeFree 22156293 Detail
0.030 colorectal cancer In the present study, we investigated the role in colorectal cancer of single-nu... BeFree 18006925 Detail
0.012 Carcinoma of lung GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk fact... BeFree 15896461 Detail
0.005 breast carcinoma We evaluated associations between seven single-nucleotide polymorphisms in four ... BeFree 21622940 Detail
<0.001 melanoma We hypothesized that common nsSNPs of BER genes, specifically ADPRT rs1136410, X... BeFree 22687647 Detail
0.006 colorectal carcinoma Association of hOGG1 Ser326Cys polymorphism with colorectal cancer risk: an upda... BeFree 25227662 Detail
0.058 colorectal cancer In the present study, we investigated the role in colorectal cancer of single-nu... BeFree 18006925 Detail
0.013 Malignant neoplasm of stomach Lack of association between Human Oxoguanine Glycosylase 1 (hOGG1) S326C polymor... BeFree 22296498 Detail
<0.001 Melanosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.002 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
0.010 Glioma No evidence of significant associations between ERCC2 rs1799793, OGG1 rs1052133,... BeFree 24500421 Detail
0.001 Malignant tumor of colon Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that... BeFree 16771692 Detail
0.480 Malignant neoplasm of breast Nonetheless, published data were consistent with associations between: (a) the O... BeFree 12496039 Detail
0.002 colon carcinoma The association of the Ser326Cys polymorphism in the 8-oxoguanine glycosylase (O... BeFree 23368532 Detail
0.007 Carcinogenesis However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg... BeFree 15840879 Detail
0.013 colorectal carcinoma In the present study, we investigated the role in colorectal cancer of single-nu... BeFree 18006925 Detail
0.026 Malignant neoplasm of breast The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis. BeFree 20058067 Detail
0.020 Malignant neoplasm of prostate The hOGG1 Ser326Cys polymorphism and prostate cancer risk: a meta-analysis of 25... BeFree 21914193 Detail
<0.001 meningitis In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, a... BeFree 21651918 Detail
0.007 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.005 Chronic Obstructive Airway Disease hOGG1 Ser326Cys and XRCC1 Arg399Gln polymorphisms associated with chronic obstru... BeFree 19493423 Detail
0.001 gallbladder carcinoma hOGG1 Ser326Cys polymorphism and susceptibility to gallbladder cancer in a Chine... BeFree 17417784 Detail
<0.001 Hyperkeratosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
<0.001 Melanosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.002 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.098 Malignant neoplasm of breast Nonetheless, published data were consistent with associations between: (a) the O... BeFree 12496039 Detail
0.008 Chronic Obstructive Airway Disease hOGG1 Ser326Cys and XRCC1 Arg399Gln polymorphisms associated with chronic obstru... BeFree 19493423 Detail
0.006 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.072 Malignant neoplasm of lung The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibili... BeFree 22540013 Detail
<0.001 gallbladder carcinoma Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
<0.001 gallbladder carcinoma Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.072 Malignant neoplasm of lung Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk. BeFree 11927502 Detail
0.013 Esophageal Neoplasms Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese ... BeFree 11307145 Detail
<0.001 Hyperkeratosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.030 Malignant neoplasm of urinary bladder hOGG1 Ser326Cys polymorphism is associated with risk of bladder cancer in a Chin... BeFree 22463382 Detail
0.009 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
<0.001 Gastro-esophageal reflux disease with esophagitis In a population-based case-control study, we examined associations of the hOGG1 ... BeFree 18349297 Detail
0.018 breast carcinoma We evaluated associations between seven single-nucleotide polymorphisms in four ... BeFree 21622940 Detail
0.030 colorectal cancer The meta-analysis suggests that OGG1 rs1052133 polymorphism is significantly ass... BeFree 23975367 Detail
0.030 colorectal cancer DNA repair gene 8-oxoguanine DNA glycosylase Ser326Cys polymorphism and colorect... BeFree 21899442 Detail
<0.001 gallbladder carcinoma Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.129 Diabetes Mellitus, Non-Insulin-Dependent The association of the Ser326Cys polymorphism of the 8-oxoguanine glycosylase 1 ... BeFree 19486888 Detail
0.006 Leukoplakia We examined the association of 13 variants in eight genes (rs4646903, rs2031920,... BeFree 21741876 Detail
0.156 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
<0.001 Secondary malignant neoplasm of lymph node We observed a strong association between the G/C genotype of the RAD51-135 G/C p... BeFree 18977234 Detail
0.006 colorectal carcinoma In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorp... BeFree 25323581 Detail
0.013 Carcinoma of lung The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis. BeFree 18628426 Detail
<0.001 Malignant tumor of cervix Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of... BeFree 15990162 Detail
0.001 prostate carcinoma We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
<0.001 Glaucoma, Primary Open Angle Association of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326Ser/Cys OGG1,... BeFree 23499241 Detail
0.026 Malignant neoplasm of breast Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... BeFree 20183911 Detail
0.026 Malignant neoplasm of breast Lack of association between the hOGG1 Ser326Cys polymorphism and breast cancer r... BeFree 20054639 Detail
0.047 Malignant neoplasm of prostate We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.072 Malignant neoplasm of lung Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lun... BeFree 23065211 Detail
0.007 prostate carcinoma We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
<0.001 keratosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
<0.001 gallbladder carcinoma Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.030 colorectal cancer Polymorphism OGG1 S326C was associated with an increased risk of colorectal canc... BeFree 16609022 Detail
0.001 Carcinoma of lung Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that... BeFree 16771692 Detail
0.006 colorectal carcinoma In the present study, we investigated the role in colorectal cancer of single-nu... BeFree 18006925 Detail
0.030 Malignant neoplasm of urinary bladder An association between hOGG1 Ser326Cys polymorphism and the risk of bladder canc... BeFree 22857644 Detail
0.072 Malignant neoplasm of lung GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk fact... BeFree 15896461 Detail
0.013 Carcinoma of lung Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidenc... BeFree 24085357 Detail
<0.001 Cancer of Digestive System The hOGG1 Ser326Cys polymorphism contributes to digestive system cancer suscepti... BeFree 25323581 Detail
0.020 Carcinoma of lung For example, there was a positive association between the OGG1 Ser326Cys variant... BeFree 23023028 Detail
0.124 Adenocarcinoma of lung (disorder) A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the l... BeFree 12164330 Detail
0.072 Malignant neoplasm of lung Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and veg... BeFree 17015267 Detail
0.006 stomach carcinoma Lack of association between the hOGG1 Ser326Cys polymorphism and gastric cancer ... BeFree 22799296 Detail
0.030 colorectal cancer GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colore... BeFree 15946795 Detail
0.007 Diabetes Mellitus, Non-Insulin-Dependent According to our study results, it has been observed that the combined evaluatio... BeFree 22652274 Detail
0.003 Cancer of Head and Neck MUTYH Tyr165Cys, OGG1 Ser326Cys and XPD Lys751Gln polymorphisms and head neck ca... BeFree 20571908 Detail
<0.001 peptic esophagitis In a population-based case-control study, we examined associations of the hOGG1 ... BeFree 18349297 Detail
0.072 Malignant neoplasm of lung Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidenc... BeFree 24085357 Detail
0.124 Adenocarcinoma of lung (disorder) In summary, this meta-analysis indicates that OGG1 Ser326Cys show an increased l... BeFree 23065211 Detail
<0.001 Mixed type cataract The genotype frequency of the Ser/Ser of OGG1-Ser326Cys was significantly differ... BeFree 22306120 Detail
<0.001 Melanosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
<0.001 Malignant neoplasm of gastrointestinal tract These findings supported that hOGG1 Ser326Cys polymorphism may contribute to the... BeFree 25323581 Detail
<0.001 Gastro-esophageal reflux disease with esophagitis In a population-based case-control study, we examined associations of the hOGG1 ... BeFree 18349297 Detail
0.005 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
0.072 Malignant neoplasm of lung OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a pro... BeFree 18155253 Detail
0.001 esophageal carcinoma Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese ... BeFree 11307145 Detail
<0.001 Rectal Carcinoma We genotyped 1,181 controls and 311 cases (180 colon and 131 rectal cancer) for ... BeFree 20559012 Detail
0.030 colorectal cancer The analysis of binary genotype combinations showed increased colorectal cancer ... BeFree 17991492 Detail
<0.001 Congenital chromosomal disease Our study is focused on the extent of any such chromosomal aberrations with resp... BeFree 21858514 Detail
0.013 Carcinoma of lung GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk fact... BeFree 15896461 Detail
0.013 cervix carcinoma Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of... BeFree 15990162 Detail
0.004 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
0.006 stomach carcinoma To evaluate the association between genetic polymorphisms of X-ray repair cross-... BeFree 19147860 Detail
0.030 colorectal cancer Association of hOGG1 Ser326Cys polymorphism with colorectal cancer risk: an upda... BeFree 25227662 Detail
0.026 Malignant neoplasm of breast Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast ... BeFree 24893568 Detail
0.007 liver carcinoma hOGG1 Ser326Cys polymorphism and risk of hepatocellular carcinoma among East Asi... BeFree 23577090 Detail
0.004 Carcinoma of bladder Among four DNA repair gene polymorphisms, the OGG1 326 Ser/Cys and XPD 312 Asp/A... BeFree 25089939 Detail
<0.001 Melanosis coli Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.006 colorectal carcinoma GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colore... BeFree 15946795 Detail
0.013 Esophageal Neoplasms The OGG1 Ser326Cys polymorphism and the risk of esophageal cancer: a meta-analys... BeFree 23909557 Detail
0.006 stomach carcinoma The functional Ser326Cys polymorphism in hOGG1 is associated with gastric cancer... BeFree 22343785 Detail
0.002 Malignant neoplasm of stomach To evaluate the association between genetic polymorphisms of X-ray repair cross-... BeFree 19147860 Detail
0.013 Malignant neoplasm of stomach hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gast... BeFree 15596047 Detail
0.030 Malignant neoplasm of urinary bladder Using multifactor dimensionality reduction approach, the four-factor model, incl... BeFree 17220334 Detail
0.122 colon carcinoma Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that... BeFree 16771692 Detail
0.080 breast carcinoma Nonetheless, published data were consistent with associations between: (a) the O... BeFree 12496039 Detail
0.013 Carcinoma of lung Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that... BeFree 16771692 Detail
<0.001 Paroxysmal atrial tachycardia We investigated the association of 10 base-excision and nucleotide-excision repa... BeFree 17531525 Detail
<0.001 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
0.001 Squamous cell carcinoma of the head and neck In conclusion our data showed that the Ser326Cys polymorphism of the OGG1 gene m... BeFree 20571908 Detail
0.002 Congenital chromosomal disease Our study is focused on the extent of any such chromosomal aberrations with resp... BeFree 21858514 Detail
0.129 Diabetes Mellitus, Non-Insulin-Dependent Evidence suggests that Ser326Cys, a genetic polymorphism of human 8-oxoguanine g... BeFree 24998955 Detail
0.013 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.006 Malignant neoplasm of pancreas Association of OGG1 Ser326Cys polymorphism and pancreatic cancer susceptibility:... BeFree 24186001 Detail
0.001 esophageal carcinoma The OGG1 Ser326Cys polymorphism and the risk of esophageal cancer: a meta-analys... BeFree 23909557 Detail
0.013 Carcinoma of lung The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibili... BeFree 22540013 Detail
0.003 prostate carcinoma We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
<0.001 meningitis In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, a... BeFree 21651918 Detail
0.003 coronary artery disease The 8-oxoguanine glycosylase I (hOGG1) Ser326Cys variant affects the susceptibil... BeFree 20667409 Detail
0.013 Carcinoma of lung We demonstrated a novel, significant correlation between the hOGG1 Ser326Cys pol... BeFree 22855704 Detail
0.002 colon carcinoma hOGG1 Ser326Cys polymorphism modifies the significance of the environmental risk... BeFree 12717837 Detail
0.072 Malignant neoplasm of lung Both the XRCC1 Arg194Trp and Arg280His as well as the OGG1 Ser326Cys heterozygou... BeFree 17531525 Detail
0.003 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
<0.001 Carcinoma of lung The Ser326Cys polymorphism in the human 8-oxogunaine glycosylase (hOGG1) gene wi... BeFree 24435978 Detail
0.015 Malignant neoplasm of prostate We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.005 breast carcinoma hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women. BeFree 12779082 Detail
0.030 colorectal cancer In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorp... BeFree 25323581 Detail
0.005 breast carcinoma Nonetheless, published data were consistent with associations between: (a) the O... BeFree 12496039 Detail
0.018 breast carcinoma Nonetheless, published data were consistent with associations between: (a) the O... BeFree 12496039 Detail
0.026 Malignant neoplasm of breast Ser326Cys polymorphism in DNA repair genes hOGG1 in breast cancer women. BeFree 19391486 Detail
<0.001 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
<0.001 diabetes mellitus The association of the Ser326Cys polymorphism in the 8-oxoguanine glycosylase (O... BeFree 23368532 Detail
0.098 Malignant neoplasm of breast We evaluated associations between seven single-nucleotide polymorphisms in four ... BeFree 21622940 Detail
0.004 Carcinoma of bladder An association between hOGG1 Ser326Cys polymorphism and the risk of bladder canc... BeFree 22857644 Detail
0.026 Malignant neoplasm of breast hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women. BeFree 12779082 Detail
0.002 stomach carcinoma To evaluate the association between genetic polymorphisms of X-ray repair cross-... BeFree 19147860 Detail
0.003 colorectal carcinoma The analysis of binary genotype combinations showed increased colorectal cancer ... BeFree 17991492 Detail
0.072 Malignant neoplasm of lung We demonstrated a novel, significant correlation between the hOGG1 Ser326Cys pol... BeFree 22855704 Detail
0.013 Carcinoma of lung Association between the hOGG1 Ser326Cys polymorphism and lung cancer susceptibil... BeFree 23971971 Detail
0.013 Carcinoma of lung In a nested case-cohort design we examined associations between urinary excretio... BeFree 22044660 Detail
0.003 Malignant neoplasm of mouth In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorp... BeFree 25323581 Detail
0.072 Malignant neoplasm of lung The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis. BeFree 18628426 Detail
0.032 Malignant neoplasm of breast Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... BeFree 20183911 Detail
0.009 Malignant neoplasm of lung Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that... BeFree 16771692 Detail
<0.001 gallbladder carcinoma Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.001 Squamous cell carcinoma of the head and neck Interaction of OGG1 Ser326Cys polymorphism with cigarette smoking in head and ne... BeFree 16381036 Detail
0.002 Xeroderma Pigmentosum, Complementation Group D In a population-based case-control study, we examined associations of the hOGG1 ... BeFree 18349297 Detail
<0.001 Malignant neoplasm of gallbladder Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.004 breast carcinoma Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... BeFree 20183911 Detail
0.016 age related macular degeneration This study investigates the Hemicentin-1 (an extracellular matrix protein) Q5345... BeFree 17057786 Detail
0.004 coronary artery disease The aim of this study was to investigate the relationship between AP-endonucleas... BeFree 23368530 Detail
0.010 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.098 Malignant neoplasm of breast Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... BeFree 20183911 Detail
0.011 Malignant neoplasm of esophagus Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese ... BeFree 11307145 Detail
0.005 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.030 Malignant neoplasm of urinary bladder Among four DNA repair gene polymorphisms, the OGG1 326 Ser/Cys and XPD 312 Asp/A... BeFree 25089939 Detail
0.001 pancreatic carcinoma Association of OGG1 Ser326Cys polymorphism and pancreatic cancer susceptibility:... BeFree 24186001 Detail
0.005 breast carcinoma Lack of association between the hOGG1 Ser326Cys polymorphism and breast cancer r... BeFree 20054639 Detail
0.012 colorectal cancer The analysis of binary genotype combinations showed increased colorectal cancer ... BeFree 17991492 Detail
0.002 breast carcinoma We evaluated associations between seven single-nucleotide polymorphisms in four ... BeFree 21622940 Detail
<0.001 Meningitis, Bacterial In recent papers published by our group, we described the associations between t... BeFree 26316174 Detail
<0.001 Hearing Loss, Mixed Conductive-Sensorineural A functional Ser326Cys polymorphism in hOGG1 is associated with noise-induced he... BeFree 24599382 Detail
<0.001 Hodgkin Disease In the present study, performed on blood DNA from 91 HD subjects, we observed th... BeFree 19857538 Detail
0.012 Cancer of Head and Neck MUTYH Tyr165Cys, OGG1 Ser326Cys and XPD Lys751Gln polymorphisms and head neck ca... BeFree 20571908 Detail
0.013 Malignant neoplasm of stomach The significant effects of hOGG1 Ser326Cys polymorphism on colorectal, breast, b... BeFree 22114677 Detail
0.013 Malignant neoplasm of stomach The functional Ser326Cys polymorphism in hOGG1 is associated with gastric cancer... BeFree 22343785 Detail
0.005 Tooth Loss Association of the OGG1 Ser326Cys polymorphism with tooth loss. BeFree 16538639 Detail
0.008 Secondary malignant neoplasm of lymph node We observed a strong association between the G/C genotype of the RAD51-135 G/C p... BeFree 18977234 Detail
0.002 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
0.008 Malignant neoplasm of prostate We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.019 Malignant neoplasm of breast Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast ... BeFree 24893568 Detail
0.012 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
<0.001 Secondary malignant neoplasm of lymph node We observed a strong association between the G/C genotype of the RAD51-135 G/C p... BeFree 18977234 Detail
0.002 Non-small cell lung carcinoma The results indicated that the hOGG1 Ser326Cys polymorphism might contribute to ... BeFree 21790253 Detail
0.006 colorectal carcinoma DNA repair gene 8-oxoguanine DNA glycosylase Ser326Cys polymorphism and colorect... BeFree 21899442 Detail
<0.001 Malignant neoplasm of gallbladder Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.020 Malignant neoplasm of prostate These results suggest that hOGG1 may have a role in the repair of 8-OH-dG adduct... BeFree 14634453 Detail
0.003 Carcinoma of lung We investigated the association of 10 base-excision and nucleotide-excision repa... BeFree 17531525 Detail
<0.001 Meningitis, Bacterial In recent papers published by our group, we described the associations between t... BeFree 26316174 Detail
0.006 stomach carcinoma hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gast... BeFree 15596047 Detail
<0.001 meningitis In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, a... BeFree 21651918 Detail
<0.001 Meningitis, Bacterial In recent papers published by our group, we described the associations between t... BeFree 26316174 Detail
0.001 Malignant neoplasm of endometrium The hOGG1 Ser326Cys may not play an important role in susceptibility to endometr... BeFree 21866464 Detail
0.011 Malignant neoplasm of esophagus The OGG1 Ser326Cys polymorphism and the risk of esophageal cancer: a meta-analys... BeFree 23909557 Detail
0.010 Xeroderma Pigmentosum, Complementation Group D In a population-based case-control study, we examined associations of the hOGG1 ... BeFree 18349297 Detail
0.006 colorectal carcinoma Polymorphism OGG1 S326C was associated with an increased risk of colorectal canc... BeFree 16609022 Detail
0.006 stomach carcinoma The significant effects of hOGG1 Ser326Cys polymorphism on colorectal, breast, b... BeFree 22114677 Detail
0.072 Malignant neoplasm of lung For example, there was a positive association between the OGG1 Ser326Cys variant... BeFree 23023028 Detail
0.013 Carcinoma of lung Association of the hOGG1 Ser326Cys polymorphism with increased lung cancer susce... BeFree 21790253 Detail
0.072 Malignant neoplasm of lung OGG1 S326C homozygote was suggested to be associated with lung cancer risk in Ca... BeFree 18990748 Detail
0.004 prostate carcinoma The hOGG1 Ser326Cys polymorphism and prostate cancer risk: a meta-analysis of 25... BeFree 21914193 Detail
0.005 breast carcinoma Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast ... BeFree 24893568 Detail
0.009 Carcinoma of lung Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lun... BeFree 23065211 Detail
<0.001 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
0.030 Malignant neoplasm of urinary bladder Lack of association between hOGG1 Ser326Cys polymorphism and the risk of bladder... BeFree 22156293 Detail
0.001 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
<0.001 Leukemia, Lymphocytic, Acute, L1 hOGG1 Ser326Cys polymorphism and risk of childhood acute lymphoblastic leukemia ... BeFree 21401806 Detail
<0.001 keratosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.013 Carcinoma of lung OGG1 S326C homozygote was suggested to be associated with lung cancer risk in Ca... BeFree 18990748 Detail
0.003 Malignant tumor of cervix Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of... BeFree 15990162 Detail
0.100 Malignant neoplasm of lung For example, there was a positive association between the OGG1 Ser326Cys variant... BeFree 23023028 Detail
0.013 Carcinoma of lung Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and veg... BeFree 17015267 Detail
0.013 Carcinoma of lung Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lun... BeFree 23065211 Detail
0.006 colorectal carcinoma The analysis of binary genotype combinations showed increased colorectal cancer ... BeFree 17991492 Detail
<0.001 Malignant neoplasm of liver In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorp... BeFree 25323581 Detail
<0.001 Meningitis, Bacterial For the SNP OGG1 Ser326Cys, the genotype Cys/Cys was more frequent (P&lt;0.05) i... BeFree 21651918 Detail
0.003 Malignant tumor of colon Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that... BeFree 16771692 Detail
0.002 Xeroderma Pigmentosum, Complementation Group D The present meta-analysis has limited evidence to support the association of XPD... BeFree 23271362 Detail
0.001 prostate carcinoma We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.006 adenoma Tubular adenomas or adenomas with none-to-mild dysplasia were significantly asso... BeFree 17252231 Detail
0.001 Rectal Carcinoma We genotyped 1,181 controls and 311 cases (180 colon and 131 rectal cancer) for ... BeFree 20559012 Detail
0.028 Malignant neoplasm of urinary bladder Using multifactor dimensionality reduction approach, the four-factor model, incl... BeFree 17220334 Detail
0.026 Malignant neoplasm of breast We evaluated associations between seven single-nucleotide polymorphisms in four ... BeFree 21622940 Detail
0.001 Squamous cell carcinoma of the head and neck Role of OGG1 Ser326Cys polymorphism and 8-oxoguanine DNA damage in risk assessme... BeFree 21986195 Detail
0.001 Malignant tumor of colon hOGG1 Ser326Cys polymorphism modifies the significance of the environmental risk... BeFree 12717837 Detail
0.123 Huntington disease In the present study, performed on blood DNA from 91 HD subjects, we observed th... BeFree 19857538 Detail
0.004 Malignant neoplasm of prostate We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.001 Malignant neoplasm of gallbladder Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
<0.001 Hepatocarcinogenesis These results suggest that the hOGG1 Ser326Cys polymorphism may not play a major... BeFree 17085873 Detail
0.072 Malignant neoplasm of lung The association of OGG1 Ser326Cys polymorphism and urinary 8-OHdG levels with lu... BeFree 19064361 Detail
<0.001 Carcinoma of bladder We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases a... BeFree 19815090 Detail
0.001 Malignant neoplasm of gallbladder hOGG1 Ser326Cys polymorphism and susceptibility to gallbladder cancer in a Chine... BeFree 17417784 Detail
0.013 Esophageal Neoplasms OGG1 Ser326Cys polymorphism and susceptibility to esophageal cancer in low and h... BeFree 20069464 Detail
0.002 Cancer of Head and Neck MUTYH Tyr165Cys, OGG1 Ser326Cys and XPD Lys751Gln polymorphisms and head neck ca... BeFree 20571908 Detail
0.004 prostate carcinoma These results suggest that hOGG1 may have a role in the repair of 8-OH-dG adduct... BeFree 14634453 Detail
0.030 colorectal cancer Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-a... BeFree 21695387 Detail
0.002 Non-small cell lung carcinoma This study investigated polymorphisms of OGG1 Ser326Cys, APE1 Asp148Glu APE1-141... BeFree 24729390 Detail
0.002 Congenital chromosomal disease Our study is focused on the extent of any such chromosomal aberrations with resp... BeFree 21858514 Detail
0.007 liver carcinoma Polymorphisms of excision repair gene XPD Lys751Gln and hOGG1 Ser326Cys might no... BeFree 23271362 Detail
0.001 Squamous cell carcinoma of esophagus NEIL1 reference SNP 4462560 (rs4462560) and rs7402844, hOGG1 rs1052133 and rs293... BeFree 24022861 Detail
0.007 Carcinogenesis The authors found that the ERCC2 Asp312Asn AA, MSH2 IVS1 + 9G &gt; C CC, OGG1 Se... BeFree 20564624 Detail
0.005 breast carcinoma Ser326Cys polymorphism in DNA repair genes hOGG1 in breast cancer women. BeFree 19391486 Detail
0.018 breast carcinoma Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... BeFree 20183911 Detail
0.036 Malignant neoplasm of lung We investigated the association of 10 base-excision and nucleotide-excision repa... BeFree 17531525 Detail
0.005 breast carcinoma Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast ... BeFree 24893568 Detail
0.092 Malignant neoplasm of lung GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk fact... BeFree 15896461 Detail
0.018 Malignant neoplasm of stomach To evaluate the association between genetic polymorphisms of X-ray repair cross-... BeFree 19147860 Detail
0.006 colorectal carcinoma The meta-analysis suggests that OGG1 rs1052133 polymorphism is significantly ass... BeFree 23975367 Detail
<0.001 Malignant neoplasm of gallbladder Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.023 Malignant neoplasm of breast We evaluated associations between seven single-nucleotide polymorphisms in four ... BeFree 21622940 Detail
0.006 Carcinogenesis However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg... BeFree 15840879 Detail
0.005 breast carcinoma Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... BeFree 20183911 Detail
0.030 colorectal cancer Meta-analysis of the association between hOGG1 Ser326Cys polymorphism and risk o... BeFree 22526153 Detail
0.004 Carcinoma of bladder Meta-analysis demonstrates lack of association of the hOGG1 Ser326Cys polymorphi... BeFree 23079842 Detail
0.001 Adenocarcinoma of lung (disorder) In summary, this meta-analysis indicates that OGG1 Ser326Cys show an increased l... BeFree 23065211 Detail
<0.001 Adenoma of large intestine GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colore... BeFree 15946795 Detail
0.006 stomach carcinoma Association of hOGG1 Ser326Cys polymorphism with gastric cancer risk: a meta-ana... BeFree 22294108 Detail
0.007 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
<0.001 Melanosis coli Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.062 colorectal cancer In the present study, we investigated the role in colorectal cancer of single-nu... BeFree 18006925 Detail
0.072 Malignant neoplasm of lung hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis. BeFree 24435978 Detail
0.008 stomach carcinoma To evaluate the association between genetic polymorphisms of X-ray repair cross-... BeFree 19147860 Detail
0.030 Malignant neoplasm of urinary bladder Meta-analysis demonstrates lack of association of the hOGG1 Ser326Cys polymorphi... BeFree 23079842 Detail
0.013 Carcinoma of lung hOGG1 Ser326Cys polymorphism and lung cancer susceptibility. BeFree 10744126 Detail
0.013 Carcinoma of lung For example, there was a positive association between the OGG1 Ser326Cys variant... BeFree 23023028 Detail
0.013 Carcinoma of lung Both the XRCC1 Arg194Trp and Arg280His as well as the OGG1 Ser326Cys heterozygou... BeFree 17531525 Detail
0.012 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
0.006 stomach carcinoma Lack of association between the 8-oxoguanine DNA glycosylase gene Ser326Cys poly... BeFree 22471492 Detail
<0.001 Malignant neoplasm of urinary bladder We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases a... BeFree 19815090 Detail
0.004 Non-small cell lung carcinoma Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8... BeFree 16195237 Detail
<0.001 Lip and oral cavity carcinoma In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorp... BeFree 25323581 Detail
0.004 Carcinoma of bladder Using multifactor dimensionality reduction approach, the four-factor model, incl... BeFree 17220334 Detail
0.013 Carcinoma of lung Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk. BeFree 11927502 Detail
<0.001 keratosis Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.049 Malignant neoplasm of lung Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lun... BeFree 23065211 Detail
0.120 male infertility OGG1 Ser326Cys polymorphism interacts with cigarette smoking to increase oxidati... BeFree 23376476 Detail
0.001 esophageal carcinoma OGG1 Ser326Cys polymorphism and susceptibility to esophageal cancer in low and h... BeFree 20069464 Detail
0.124 Adenocarcinoma of lung (disorder) Association of the OGG1-Ser326Cys polymorphism with lung adenocarcinoma risk. BeFree 16800823 Detail
0.005 cervix carcinoma Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of... BeFree 15990162 Detail
0.001 Squamous cell carcinoma of esophagus A meta-analysis of the association between the hOGG1 Ser326Cys polymorphism and ... BeFree 23762419 Detail
0.084 Carcinoma of lung We investigated the association of 10 base-excision and nucleotide-excision repa... BeFree 17531525 Detail
<0.001 Glaucoma, Primary Open Angle Association of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326Ser/Cys OGG1,... BeFree 23499241 Detail
<0.001 Malignant neoplasm of gallbladder Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.001 gallbladder carcinoma Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
<0.001 Malignant neoplasm of gallbladder Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&... BeFree 21283657 Detail
0.013 Malignant neoplasm of stomach To evaluate the association between genetic polymorphisms of X-ray repair cross-... BeFree 19147860 Detail
0.006 stomach carcinoma Lack of association between Human Oxoguanine Glycosylase 1 (hOGG1) S326C polymor... BeFree 22296498 Detail
0.013 Malignant neoplasm of stomach Association of hOGG1 Ser326Cys polymorphism with gastric cancer risk: a meta-ana... BeFree 22294108 Detail
0.002 Cancer of Head and Neck HOGG1 Ser326Cys polymorphism and susceptibility to head and neck cancer: a meta-... BeFree 22320944 Detail
0.072 Malignant neoplasm of lung Association of the hOGG1 Ser326Cys polymorphism with increased lung cancer susce... BeFree 21790253 Detail
<0.001 peptic esophagitis In a population-based case-control study, we examined associations of the hOGG1 ... BeFree 18349297 Detail
0.006 colorectal carcinoma Meta-analysis of the association between hOGG1 Ser326Cys polymorphism and risk o... BeFree 22526153 Detail
0.006 Leukoplakia We examined the association of 13 variants in eight genes (rs4646903, rs2031920,... BeFree 21741876 Detail
0.007 liver carcinoma hOGG1 Ser326Cys polymorphism and risk of hepatocellular carcinoma among Japanese... BeFree 17085873 Detail
0.072 Malignant neoplasm of lung hOGG1 Ser326Cys polymorphism and lung cancer susceptibility. BeFree 10744126 Detail
<0.001 Melanosis coli Data from a case-control study of 792 cases and 792 matched controls conducted i... BeFree 17374727 Detail
0.007 liver carcinoma No association between hOGG1 Ser326Cys polymorphism and hepatocellular carcinoma... BeFree 23186590 Detail
0.072 Malignant neoplasm of lung Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that... BeFree 16771692 Detail
0.013 Carcinoma of lung hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis. BeFree 24435978 Detail
0.044 Malignant neoplasm of lung We investigated the association of 10 base-excision and nucleotide-excision repa... BeFree 17531525 Detail
0.011 Malignant neoplasm of esophagus OGG1 Ser326Cys polymorphism and susceptibility to esophageal cancer in low and h... BeFree 20069464 Detail
0.002 colon carcinoma Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that... BeFree 16771692 Detail
0.002 Carcinoma of bladder Using multifactor dimensionality reduction approach, the four-factor model, incl... BeFree 17220334 Detail
0.013 Carcinoma of lung OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a pro... BeFree 18155253 Detail
0.003 coronary artery disease The aim of this study was to investigate the relationship between AP-endonucleas... BeFree 23368530 Detail
<0.001 Age-related cataract Results suggest that the Cys/Cys genotype of the OGG1-Ser326Cys polymorphism may... BeFree 22306120 Detail
0.013 Malignant neoplasm of stomach Lack of association between the 8-oxoguanine DNA glycosylase gene Ser326Cys poly... BeFree 22471492 Detail
0.026 Malignant neoplasm of breast Nonetheless, published data were consistent with associations between: (a) the O... BeFree 12496039 Detail
Annotation

Annotations

DescrptionSourceLinks
NM_002542.6(OGG1):c.977C>G (p.Ser326Cys) AND OGG1-related disorder ClinVar Detail
Seven interactions were statistically significant after adjusting for multiple testing (FDR Q-value ... DisGeNET Detail
Seven interactions were statistically significant after adjusting for multiple testing (FDR Q-value ... DisGeNET Detail
Seven interactions were statistically significant after adjusting for multiple testing (FDR Q-value ... DisGeNET Detail
Seven interactions were statistically significant after adjusting for multiple testing (FDR Q-value ... DisGeNET Detail
Seven interactions were statistically significant after adjusting for multiple testing (FDR Q-value ... DisGeNET Detail
Seven interactions were statistically significant after adjusting for multiple testing (FDR Q-value ... DisGeNET Detail
(i) to determine the extent of oxidative stress and DNA damage and repair using a panel of selected ... DisGeNET Detail
(i) to determine the extent of oxidative stress and DNA damage and repair using a panel of selected ... DisGeNET Detail
Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-analysis. DisGeNET Detail
According to our study results, it has been observed that the combined evaluation of GSTM1-GSTT1-GST... DisGeNET Detail
Association between the hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis... DisGeNET Detail
The association of OGG1 Ser326Cys polymorphism and urinary 8-OHdG levels with lung cancer susceptibi... DisGeNET Detail
Lack of association between the hOGG1 Ser326Cys polymorphism and gastric cancer risk: a meta-analysi... DisGeNET Detail
In a nested case-cohort design we examined associations between urinary excretion of 8-oxoGua and ri... DisGeNET Detail
Protective association exhibited by the single nucleotide polymorphism (SNP) rs1052133 in the gene h... DisGeNET Detail
hOGG1 Ser326Cys polymorphism is associated with risk of bladder cancer in a Chinese population: a ca... DisGeNET Detail
The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis. DisGeNET Detail
hOGG1 Ser326Cys polymorphism and renal cell carcinoma risk in a Chinese population. DisGeNET Detail
Moreover, among smokers carrying the OGG1 Ser326Cys polymorphism, there was a tendency toward an inc... DisGeNET Detail
The hOGG1 Ser326Cys may not play an important role in susceptibility to endometrial cancer in Polish... DisGeNET Detail
In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
Lack of association between hOGG1 Ser326Cys polymorphism and the risk of bladder cancer: a meta-anal... DisGeNET Detail
In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... DisGeNET Detail
GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer i... DisGeNET Detail
We evaluated associations between seven single-nucleotide polymorphisms in four DNA repair genes (ER... DisGeNET Detail
We hypothesized that common nsSNPs of BER genes, specifically ADPRT rs1136410, XRCC1 rs25487, rs2548... DisGeNET Detail
Association of hOGG1 Ser326Cys polymorphism with colorectal cancer risk: an updated meta-analysis in... DisGeNET Detail
In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... DisGeNET Detail
Lack of association between Human Oxoguanine Glycosylase 1 (hOGG1) S326C polymorphism and the risk o... DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
No evidence of significant associations between ERCC2 rs1799793, OGG1 rs1052133, XRCC1 rs25489, XRCC... DisGeNET Detail
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant ... DisGeNET Detail
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... DisGeNET Detail
The association of the Ser326Cys polymorphism in the 8-oxoguanine glycosylase (OGG1) gene with a col... DisGeNET Detail
However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg194Trp polymorphisms... DisGeNET Detail
In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... DisGeNET Detail
The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis. DisGeNET Detail
The hOGG1 Ser326Cys polymorphism and prostate cancer risk: a meta-analysis of 2584 cases and 3234 co... DisGeNET Detail
In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, and PARP-1 Val762Ala ... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
hOGG1 Ser326Cys and XRCC1 Arg399Gln polymorphisms associated with chronic obstructive pulmonary dise... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and susceptibility to gallbladder cancer in a Chinese population. DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... DisGeNET Detail
hOGG1 Ser326Cys and XRCC1 Arg399Gln polymorphisms associated with chronic obstructive pulmonary dise... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis ... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk. DisGeNET Detail
Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population. DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
hOGG1 Ser326Cys polymorphism is associated with risk of bladder cancer in a Chinese population: a ca... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
In a population-based case-control study, we examined associations of the hOGG1 Ser 326 Cys, XRCC1 A... DisGeNET Detail
We evaluated associations between seven single-nucleotide polymorphisms in four DNA repair genes (ER... DisGeNET Detail
The meta-analysis suggests that OGG1 rs1052133 polymorphism is significantly associated with the ris... DisGeNET Detail
DNA repair gene 8-oxoguanine DNA glycosylase Ser326Cys polymorphism and colorectal cancer risk in a ... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
The association of the Ser326Cys polymorphism of the 8-oxoguanine glycosylase 1 (OGG1) gene with typ... DisGeNET Detail
We examined the association of 13 variants in eight genes (rs4646903, rs2031920, rs3813867, GSTM1 nu... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
We observed a strong association between the G/C genotype of the RAD51-135 G/C polymorphism and the ... DisGeNET Detail
In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorphism may increase he... DisGeNET Detail
The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis. DisGeNET Detail
Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Association of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326Ser/Cys OGG1, and the 324Gln/His ... DisGeNET Detail
Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... DisGeNET Detail
Lack of association between the hOGG1 Ser326Cys polymorphism and breast cancer risk: evidence from 1... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lung cancer risk: a met... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
Polymorphism OGG1 S326C was associated with an increased risk of colorectal cancer [odds ratio (OR),... DisGeNET Detail
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant ... DisGeNET Detail
In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... DisGeNET Detail
An association between hOGG1 Ser326Cys polymorphism and the risk of bladder cancer in non-smokers: a... DisGeNET Detail
GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer i... DisGeNET Detail
Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidence from a meta-analys... DisGeNET Detail
The hOGG1 Ser326Cys polymorphism contributes to digestive system cancer susceptibility: evidence fro... DisGeNET Detail
For example, there was a positive association between the OGG1 Ser326Cys variant and gastric and lun... DisGeNET Detail
A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung. DisGeNET Detail
Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and vegetables in relation ... DisGeNET Detail
Lack of association between the hOGG1 Ser326Cys polymorphism and gastric cancer risk: a meta-analysi... DisGeNET Detail
GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and co... DisGeNET Detail
According to our study results, it has been observed that the combined evaluation of GSTM1-GSTT1-GST... DisGeNET Detail
MUTYH Tyr165Cys, OGG1 Ser326Cys and XPD Lys751Gln polymorphisms and head neck cancer susceptibility:... DisGeNET Detail
In a population-based case-control study, we examined associations of the hOGG1 Ser 326 Cys, XRCC1 A... DisGeNET Detail
Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidence from a meta-analys... DisGeNET Detail
In summary, this meta-analysis indicates that OGG1 Ser326Cys show an increased lung cancer risk in A... DisGeNET Detail
The genotype frequency of the Ser/Ser of OGG1-Ser326Cys was significantly different in the cortical ... DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
These findings supported that hOGG1 Ser326Cys polymorphism may contribute to the susceptibility of d... DisGeNET Detail
In a population-based case-control study, we examined associations of the hOGG1 Ser 326 Cys, XRCC1 A... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study. DisGeNET Detail
Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population. DisGeNET Detail
We genotyped 1,181 controls and 311 cases (180 colon and 131 rectal cancer) for SNPs in the XRCC1 (A... DisGeNET Detail
The analysis of binary genotype combinations showed increased colorectal cancer risk in individuals ... DisGeNET Detail
Our study is focused on the extent of any such chromosomal aberrations with respect to chromium leve... DisGeNET Detail
GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer i... DisGeNET Detail
Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in ... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... DisGeNET Detail
Association of hOGG1 Ser326Cys polymorphism with colorectal cancer risk: an updated meta-analysis in... DisGeNET Detail
Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast cancer risk: a meta-... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and risk of hepatocellular carcinoma among East Asians: a meta-analysis... DisGeNET Detail
Among four DNA repair gene polymorphisms, the OGG1 326 Ser/Cys and XPD 312 Asp/Asn heterozygous geno... DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and co... DisGeNET Detail
The OGG1 Ser326Cys polymorphism and the risk of esophageal cancer: a meta-analysis. DisGeNET Detail
The functional Ser326Cys polymorphism in hOGG1 is associated with gastric cancer risk: evidence from... DisGeNET Detail
To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... DisGeNET Detail
hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in J... DisGeNET Detail
Using multifactor dimensionality reduction approach, the four-factor model, including smoking status... DisGeNET Detail
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant ... DisGeNET Detail
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... DisGeNET Detail
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant ... DisGeNET Detail
We investigated the association of 10 base-excision and nucleotide-excision repair gene polymorphism... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
In conclusion our data showed that the Ser326Cys polymorphism of the OGG1 gene may modify the risk o... DisGeNET Detail
Our study is focused on the extent of any such chromosomal aberrations with respect to chromium leve... DisGeNET Detail
Evidence suggests that Ser326Cys, a genetic polymorphism of human 8-oxoguanine glycosylase 1 (hOGG1)... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Association of OGG1 Ser326Cys polymorphism and pancreatic cancer susceptibility: evidence from a met... DisGeNET Detail
The OGG1 Ser326Cys polymorphism and the risk of esophageal cancer: a meta-analysis. DisGeNET Detail
The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, and PARP-1 Val762Ala ... DisGeNET Detail
The 8-oxoguanine glycosylase I (hOGG1) Ser326Cys variant affects the susceptibility to multi-vessel ... DisGeNET Detail
We demonstrated a novel, significant correlation between the hOGG1 Ser326Cys polymorphism and increa... DisGeNET Detail
hOGG1 Ser326Cys polymorphism modifies the significance of the environmental risk factor for colon ca... DisGeNET Detail
Both the XRCC1 Arg194Trp and Arg280His as well as the OGG1 Ser326Cys heterozygous genotypes were ass... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
The Ser326Cys polymorphism in the human 8-oxogunaine glycosylase (hOGG1) gene with lung cancer susce... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women. DisGeNET Detail
In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorphism may increase he... DisGeNET Detail
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... DisGeNET Detail
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... DisGeNET Detail
Ser326Cys polymorphism in DNA repair genes hOGG1 in breast cancer women. DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
The association of the Ser326Cys polymorphism in the 8-oxoguanine glycosylase (OGG1) gene with a col... DisGeNET Detail
We evaluated associations between seven single-nucleotide polymorphisms in four DNA repair genes (ER... DisGeNET Detail
An association between hOGG1 Ser326Cys polymorphism and the risk of bladder cancer in non-smokers: a... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women. DisGeNET Detail
To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... DisGeNET Detail
The analysis of binary genotype combinations showed increased colorectal cancer risk in individuals ... DisGeNET Detail
We demonstrated a novel, significant correlation between the hOGG1 Ser326Cys polymorphism and increa... DisGeNET Detail
Association between the hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis... DisGeNET Detail
In a nested case-cohort design we examined associations between urinary excretion of 8-oxoGua and ri... DisGeNET Detail
In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorphism may increase he... DisGeNET Detail
The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis. DisGeNET Detail
Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... DisGeNET Detail
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant ... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
Interaction of OGG1 Ser326Cys polymorphism with cigarette smoking in head and neck squamous cell car... DisGeNET Detail
In a population-based case-control study, we examined associations of the hOGG1 Ser 326 Cys, XRCC1 A... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... DisGeNET Detail
This study investigates the Hemicentin-1 (an extracellular matrix protein) Q5345R, hOgg1 (DNA repair... DisGeNET Detail
The aim of this study was to investigate the relationship between AP-endonuclease-1 (Asp148Glu), XRC... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... DisGeNET Detail
Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population. DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Among four DNA repair gene polymorphisms, the OGG1 326 Ser/Cys and XPD 312 Asp/Asn heterozygous geno... DisGeNET Detail
Association of OGG1 Ser326Cys polymorphism and pancreatic cancer susceptibility: evidence from a met... DisGeNET Detail
Lack of association between the hOGG1 Ser326Cys polymorphism and breast cancer risk: evidence from 1... DisGeNET Detail
The analysis of binary genotype combinations showed increased colorectal cancer risk in individuals ... DisGeNET Detail
We evaluated associations between seven single-nucleotide polymorphisms in four DNA repair genes (ER... DisGeNET Detail
In recent papers published by our group, we described the associations between the single nucleotide... DisGeNET Detail
A functional Ser326Cys polymorphism in hOGG1 is associated with noise-induced hearing loss in a Chin... DisGeNET Detail
In the present study, performed on blood DNA from 91 HD subjects, we observed that bearers of the mu... DisGeNET Detail
MUTYH Tyr165Cys, OGG1 Ser326Cys and XPD Lys751Gln polymorphisms and head neck cancer susceptibility:... DisGeNET Detail
The significant effects of hOGG1 Ser326Cys polymorphism on colorectal, breast, bladder, prostate, es... DisGeNET Detail
The functional Ser326Cys polymorphism in hOGG1 is associated with gastric cancer risk: evidence from... DisGeNET Detail
Association of the OGG1 Ser326Cys polymorphism with tooth loss. DisGeNET Detail
We observed a strong association between the G/C genotype of the RAD51-135 G/C polymorphism and the ... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast cancer risk: a meta-... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
We observed a strong association between the G/C genotype of the RAD51-135 G/C polymorphism and the ... DisGeNET Detail
The results indicated that the hOGG1 Ser326Cys polymorphism might contribute to the risk of non-smal... DisGeNET Detail
DNA repair gene 8-oxoguanine DNA glycosylase Ser326Cys polymorphism and colorectal cancer risk in a ... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
These results suggest that hOGG1 may have a role in the repair of 8-OH-dG adducts in prostate tissue... DisGeNET Detail
We investigated the association of 10 base-excision and nucleotide-excision repair gene polymorphism... DisGeNET Detail
In recent papers published by our group, we described the associations between the single nucleotide... DisGeNET Detail
hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in J... DisGeNET Detail
In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, and PARP-1 Val762Ala ... DisGeNET Detail
In recent papers published by our group, we described the associations between the single nucleotide... DisGeNET Detail
The hOGG1 Ser326Cys may not play an important role in susceptibility to endometrial cancer in Polish... DisGeNET Detail
The OGG1 Ser326Cys polymorphism and the risk of esophageal cancer: a meta-analysis. DisGeNET Detail
In a population-based case-control study, we examined associations of the hOGG1 Ser 326 Cys, XRCC1 A... DisGeNET Detail
Polymorphism OGG1 S326C was associated with an increased risk of colorectal cancer [odds ratio (OR),... DisGeNET Detail
The significant effects of hOGG1 Ser326Cys polymorphism on colorectal, breast, bladder, prostate, es... DisGeNET Detail
For example, there was a positive association between the OGG1 Ser326Cys variant and gastric and lun... DisGeNET Detail
Association of the hOGG1 Ser326Cys polymorphism with increased lung cancer susceptibility in Asians:... DisGeNET Detail
OGG1 S326C homozygote was suggested to be associated with lung cancer risk in Caucasians (homozygote... DisGeNET Detail
The hOGG1 Ser326Cys polymorphism and prostate cancer risk: a meta-analysis of 2584 cases and 3234 co... DisGeNET Detail
Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast cancer risk: a meta-... DisGeNET Detail
Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lung cancer risk: a met... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
Lack of association between hOGG1 Ser326Cys polymorphism and the risk of bladder cancer: a meta-anal... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and risk of childhood acute lymphoblastic leukemia in a Chinese populat... DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
OGG1 S326C homozygote was suggested to be associated with lung cancer risk in Caucasians (homozygote... DisGeNET Detail
Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in ... DisGeNET Detail
For example, there was a positive association between the OGG1 Ser326Cys variant and gastric and lun... DisGeNET Detail
Interactions between the OGG1 Ser326Cys polymorphism and intake of fruit and vegetables in relation ... DisGeNET Detail
Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lung cancer risk: a met... DisGeNET Detail
The analysis of binary genotype combinations showed increased colorectal cancer risk in individuals ... DisGeNET Detail
In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorphism may increase he... DisGeNET Detail
For the SNP OGG1 Ser326Cys, the genotype Cys/Cys was more frequent (P&lt;0.05) in BM group. DisGeNET Detail
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant ... DisGeNET Detail
The present meta-analysis has limited evidence to support the association of XPD Lys751Gln and hOGG1... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Tubular adenomas or adenomas with none-to-mild dysplasia were significantly associated with polymorp... DisGeNET Detail
We genotyped 1,181 controls and 311 cases (180 colon and 131 rectal cancer) for SNPs in the XRCC1 (A... DisGeNET Detail
Using multifactor dimensionality reduction approach, the four-factor model, including smoking status... DisGeNET Detail
We evaluated associations between seven single-nucleotide polymorphisms in four DNA repair genes (ER... DisGeNET Detail
Role of OGG1 Ser326Cys polymorphism and 8-oxoguanine DNA damage in risk assessment of squamous cell ... DisGeNET Detail
hOGG1 Ser326Cys polymorphism modifies the significance of the environmental risk factor for colon ca... DisGeNET Detail
In the present study, performed on blood DNA from 91 HD subjects, we observed that bearers of the mu... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
These results suggest that the hOGG1 Ser326Cys polymorphism may not play a major role as an independ... DisGeNET Detail
The association of OGG1 Ser326Cys polymorphism and urinary 8-OHdG levels with lung cancer susceptibi... DisGeNET Detail
We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases and 250 controls to i... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and susceptibility to gallbladder cancer in a Chinese population. DisGeNET Detail
OGG1 Ser326Cys polymorphism and susceptibility to esophageal cancer in low and high at-risk populati... DisGeNET Detail
MUTYH Tyr165Cys, OGG1 Ser326Cys and XPD Lys751Gln polymorphisms and head neck cancer susceptibility:... DisGeNET Detail
These results suggest that hOGG1 may have a role in the repair of 8-OH-dG adducts in prostate tissue... DisGeNET Detail
Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-analysis. DisGeNET Detail
This study investigated polymorphisms of OGG1 Ser326Cys, APE1 Asp148Glu APE1-141T/G and XRCC1 Arg399... DisGeNET Detail
Our study is focused on the extent of any such chromosomal aberrations with respect to chromium leve... DisGeNET Detail
Polymorphisms of excision repair gene XPD Lys751Gln and hOGG1 Ser326Cys might not be associated with... DisGeNET Detail
NEIL1 reference SNP 4462560 (rs4462560) and rs7402844, hOGG1 rs1052133 and rs293795, and FEN1 rs4246... DisGeNET Detail
The authors found that the ERCC2 Asp312Asn AA, MSH2 IVS1 + 9G &gt; C CC, OGG1 Ser326Cys GG and CG + ... DisGeNET Detail
Ser326Cys polymorphism in DNA repair genes hOGG1 in breast cancer women. DisGeNET Detail
Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... DisGeNET Detail
We investigated the association of 10 base-excision and nucleotide-excision repair gene polymorphism... DisGeNET Detail
Association between OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and breast cancer risk: a meta-... DisGeNET Detail
GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer i... DisGeNET Detail
To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... DisGeNET Detail
The meta-analysis suggests that OGG1 rs1052133 polymorphism is significantly associated with the ris... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
We evaluated associations between seven single-nucleotide polymorphisms in four DNA repair genes (ER... DisGeNET Detail
However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg194Trp polymorphisms... DisGeNET Detail
Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... DisGeNET Detail
Meta-analysis of the association between hOGG1 Ser326Cys polymorphism and risk of colorectal cancer ... DisGeNET Detail
Meta-analysis demonstrates lack of association of the hOGG1 Ser326Cys polymorphism with bladder canc... DisGeNET Detail
In summary, this meta-analysis indicates that OGG1 Ser326Cys show an increased lung cancer risk in A... DisGeNET Detail
GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and co... DisGeNET Detail
Association of hOGG1 Ser326Cys polymorphism with gastric cancer risk: a meta-analysis. DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis. DisGeNET Detail
To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... DisGeNET Detail
Meta-analysis demonstrates lack of association of the hOGG1 Ser326Cys polymorphism with bladder canc... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and lung cancer susceptibility. DisGeNET Detail
For example, there was a positive association between the OGG1 Ser326Cys variant and gastric and lun... DisGeNET Detail
Both the XRCC1 Arg194Trp and Arg280His as well as the OGG1 Ser326Cys heterozygous genotypes were ass... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
Lack of association between the 8-oxoguanine DNA glycosylase gene Ser326Cys polymorphism and gastric... DisGeNET Detail
We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases and 250 controls to i... DisGeNET Detail
Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G&gt;C, 8902G&gt;T), XPA (-4G... DisGeNET Detail
In subgroup analyses by cancer types, we found that the hOGG1 Ser326Cys polymorphism may increase he... DisGeNET Detail
Using multifactor dimensionality reduction approach, the four-factor model, including smoking status... DisGeNET Detail
Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk. DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lung cancer risk: a met... DisGeNET Detail
OGG1 Ser326Cys polymorphism interacts with cigarette smoking to increase oxidative DNA damage in hum... DisGeNET Detail
OGG1 Ser326Cys polymorphism and susceptibility to esophageal cancer in low and high at-risk populati... DisGeNET Detail
Association of the OGG1-Ser326Cys polymorphism with lung adenocarcinoma risk. DisGeNET Detail
Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in ... DisGeNET Detail
A meta-analysis of the association between the hOGG1 Ser326Cys polymorphism and the risk of esophage... DisGeNET Detail
We investigated the association of 10 base-excision and nucleotide-excision repair gene polymorphism... DisGeNET Detail
Association of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326Ser/Cys OGG1, and the 324Gln/His ... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
Single locus analysis by logistic regression showed association of MSH2 IVS1+9G&gt;C (rs2303426), ER... DisGeNET Detail
To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... DisGeNET Detail
Lack of association between Human Oxoguanine Glycosylase 1 (hOGG1) S326C polymorphism and the risk o... DisGeNET Detail
Association of hOGG1 Ser326Cys polymorphism with gastric cancer risk: a meta-analysis. DisGeNET Detail
HOGG1 Ser326Cys polymorphism and susceptibility to head and neck cancer: a meta-analysis. DisGeNET Detail
Association of the hOGG1 Ser326Cys polymorphism with increased lung cancer susceptibility in Asians:... DisGeNET Detail
In a population-based case-control study, we examined associations of the hOGG1 Ser 326 Cys, XRCC1 A... DisGeNET Detail
Meta-analysis of the association between hOGG1 Ser326Cys polymorphism and risk of colorectal cancer ... DisGeNET Detail
We examined the association of 13 variants in eight genes (rs4646903, rs2031920, rs3813867, GSTM1 nu... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and risk of hepatocellular carcinoma among Japanese. DisGeNET Detail
hOGG1 Ser326Cys polymorphism and lung cancer susceptibility. DisGeNET Detail
Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... DisGeNET Detail
No association between hOGG1 Ser326Cys polymorphism and hepatocellular carcinoma. DisGeNET Detail
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant ... DisGeNET Detail
hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis. DisGeNET Detail
We investigated the association of 10 base-excision and nucleotide-excision repair gene polymorphism... DisGeNET Detail
OGG1 Ser326Cys polymorphism and susceptibility to esophageal cancer in low and high at-risk populati... DisGeNET Detail
Case-control studies of genetic polymorphisms in DNA repair enzymes suggest that the common variant ... DisGeNET Detail
Using multifactor dimensionality reduction approach, the four-factor model, including smoking status... DisGeNET Detail
OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study. DisGeNET Detail
The aim of this study was to investigate the relationship between AP-endonuclease-1 (Asp148Glu), XRC... DisGeNET Detail
Results suggest that the Cys/Cys genotype of the OGG1-Ser326Cys polymorphism may be associated with ... DisGeNET Detail
Lack of association between the 8-oxoguanine DNA glycosylase gene Ser326Cys polymorphism and gastric... DisGeNET Detail
Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg38
Position
chr3:9,757,089-9,757,089
Variant Type
snv
Reference Allele
C
Alternative Allele
G
Filtering Status (HGVD)
PASS
# of samples (HGVD)
1210
Mean of sample read depth (HGVD)
267.83
Standard deviation of sample read depth (HGVD)
137.76
Number of reference allele (HGVD)
1269
Number of alternative allele (HGVD)
1150
Allele Frequency (HGVD)
0.4754030591153369
Gene Symbol (HGVD)
OGG1
ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
PASS
Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
rs1052133
Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
0.4603
Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
7715
Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
16760
East Asian Chromosome Counts (ExAC)
8600
East Asian Allele Counts (ExAC)
5053
East Asian Heterozygous Counts (ExAC)
2067
East Asian Homozygous Counts (ExAC)
1493
East Asian Allele Frequency (ExAC)
0.5875581395348837
Chromosome Counts in All Race (ExAC)
120446
Allele Counts in All Race (ExAC)
32771
Heterozygous Counts in All Race (ExAC)
22385
Homozygous Counts in All Race (ExAC)
5193
Allele Frequency in All Race (ExAC)
0.27208043438553375
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