Annotation Detail

Information
Associated Genes
HMCN1
Associated Variants
SELE p.Ser149Arg (p.S149R) ( ENST00000333360.12, ENST00000367775.5, ENST00000367777.5, ENST00000367776.5, ENST00000367774.1 )
HMCN1 p.Gln5345Arg (p.Q5345R) ( ENST00000271588.9 )
OGG1 c.948+273C>G ( ENST00000302003.11, ENST00000302008.12, ENST00000302036.12, ENST00000339511.9, ENST00000344629.12, ENST00000352937.6, ENST00000383826.9, ENST00000449570.6, ENST00000707074.1 )
SELE p.Ser149Arg (p.S149R) ( ENST00000333360.12, ENST00000367774.1, ENST00000367775.5, ENST00000367776.5, ENST00000367777.5 )
HMCN1 p.Gln5345Arg (p.Q5345R) ( ENST00000271588.9 )
OGG1 c.948+273C>G ( ENST00000302003.11, ENST00000302008.12, ENST00000302036.12, ENST00000339511.9, ENST00000344629.12, ENST00000352937.6, ENST00000383826.9, ENST00000449570.6, ENST00000707074.1 )
Associated Disease
age related macular degeneration
Source Database
DisGeNET
Description
This study investigates the Hemicentin-1 (an extracellular matrix protein) Q5345R, hOgg1 (DNA repair gene) S326C, and E-selectin (an adhesion molecule) S149R SNPs in association with AMD.
Pubmed
17057786
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0164358590216495
Year of publication
2005
Drugs