Annotation Detail
Information
- Associated Genes
- OGG1
- Associated Variants
-
OGG1 c.948+273C>G
(
ENST00000302003.11,
ENST00000302008.12,
ENST00000302036.12,
ENST00000339511.9,
ENST00000344629.12,
ENST00000352937.6,
ENST00000383826.9,
ENST00000449570.6,
ENST00000707074.1 )
OGG1 c.948+273C>G ( ENST00000302003.11, ENST00000302008.12, ENST00000302036.12, ENST00000339511.9, ENST00000344629.12, ENST00000352937.6, ENST00000383826.9, ENST00000449570.6, ENST00000707074.1 ) - Associated Disease
- colorectal carcinoma
- Source Database
- DisGeNET
- Description
- The analysis of binary genotype combinations showed increased colorectal cancer risk in individuals simultaneously homozygous for the variant alleles of APE1 Asn148Glu and hOGG1 Ser326Cys (OR: 6.37; 95% CI: 1.40-29.02; p=0.02).
- Pubmed
- 17991492
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00624316305784698
- Year of publication
- 2008
Drugs