chr4:90621496:> Detail (hg19)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr4:90,621,496-90,759,466 |
| hg38 | chr4:89,700,345-89,838,315 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | cocaine abuse | NA | BeFree | Detail | |
| <0.001 | colorectal carcinoma | Detection of SNCA and FBN1 methylation in the stool as a biomarker for colorecta... | BeFree | 25802477 | Detail |
| <0.001 | Connective Tissue Diseases | NA | BeFree | Detail | |
| <0.001 | Cytomegalovirus Infections | NA | BeFree | Detail | |
| 0.005 | Cessation of life | NA | LHGDN | Detail | |
| 0.004 | Presenile dementia | NA | BeFree | Detail | |
| <0.001 | Dementia, Vascular | While all four dementia types appear to involve genes associated with tau-pathol... | BeFree | 25567624 | Detail |
| 0.080 | depressive disorder | NA | RGD | Detail | |
| <0.001 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree | Detail | |
| <0.001 | Dyskinetic syndrome | NA | BeFree | Detail | |
| 0.120 | Gaucher disease | NA | CTD_human | Detail | |
| <0.001 | hepatitis C | NA | BeFree | Detail | |
| 0.120 | Hepatolenticular Degeneration | NA | CTD_human | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| 0.120 | Lameness, Animal | NA | CTD_human | Detail | |
| <0.001 | Leukemia, T-Cell | NA | BeFree | Detail | |
| <0.001 | Adult T-Cell Lymphoma/Leukemia | NA | BeFree | Detail | |
| 0.001 | Lupus Erythematosus, Systemic | NA | BeFree | Detail | |
| 0.003 | medulloblastoma | NA | LHGDN | Detail | |
| 0.001 | melanoma | Analysis of alpha-synuclein protein was then performed in ten metastatic tissue ... | BeFree | 25333933 | Detail |
| <0.001 | Movement Disorders | NA | BeFree | Detail | |
| <0.001 | Muscle Rigidity | NA | BeFree | Detail | |
| 0.122 | Nerve Degeneration | NA | CTD_human,GAD | Detail | |
| <0.001 | nervous system disorder | NA | BeFree | Detail | |
| 0.080 | neurilemmoma | NA | RGD | Detail | |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| 0.120 | Psychoses, Substance-Induced | NA | CTD_human | Detail | |
| 0.003 | Psychotic Disorders | NA | BeFree,GAD | Detail | |
| <0.001 | restless legs syndrome | NA | BeFree | Detail | |
| 0.004 | Shy-Drager Syndrome | Interestingly, measurements of α-synuclein gene (SNCA) expression in MSA brain t... | BeFree | 25218777 | Detail |
| 0.004 | Shy-Drager Syndrome | We report here that multiple system atrophy (MSA) is caused by a different human... | BeFree | 26324905 | Detail |
| <0.001 | post-traumatic stress disorder | An α-synuclein gene (SNCA) polymorphism moderates the association of PTSD sympto... | BeFree | 25594371 | Detail |
| <0.001 | subacute sclerosing panencephalitis | NA | BeFree | Detail | |
| <0.001 | substance dependence | NA | BeFree | Detail | |
| 0.002 | Tobacco use disorder | NA | GAD | Detail | |
| <0.001 | Tremor | NA | BeFree | Detail | |
| <0.001 | tuberculosis | NA | BeFree | Detail | |
| <0.001 | vasculitis | NA | BeFree | Detail | |
| <0.001 | Virus Diseases | NA | BeFree | Detail | |
| 0.003 | Lysosomal Storage Diseases | NA | LHGDN | Detail | |
| <0.001 | Neurofibrillary degeneration (morphologic abnormality) | NA | BeFree | Detail | |
| 0.002 | Alcohol abuse | NA | GAD | Detail | |
| <0.001 | Small cell carcinoma of lung | PD-L1 and PD-1 protein expression were analysed in 94 clinical cases of small ce... | BeFree | 25582496 | Detail |
| 0.003 | adrenoleukodystrophy | NA | LHGDN | Detail | |
| <0.001 | Pick Disease of the Brain | NA | BeFree | Detail | |
| <0.001 | Cocaine delirium | NA | BeFree | Detail | |
| 0.120 | Amphetamine-Related Disorders | NA | CTD_human | Detail | |
| 0.120 | Cocaine-Related Disorders | NA | CTD_human | Detail | |
| <0.001 | Personality change | NA | BeFree | Detail | |
| 0.138 | Parkinsonian Disorders | Link between the SNCA gene and parkinsonism. | BeFree,CTD_human,LHGDN | 25554495 | Detail |
| <0.001 | brain dysfunction | NA | BeFree | Detail | |
| <0.001 | Carcinoma, Small Cell | PD-L1 and PD-1 protein expression were analysed in 94 clinical cases of small ce... | BeFree | 25582496 | Detail |
| 0.003 | essential tremor | NA | BeFree,LHGDN | Detail | |
| <0.001 | Familial Alzheimer Disease (FAD) | NA | BeFree | Detail | |
| <0.001 | Senile Plaques | NA | BeFree | Detail | |
| <0.001 | frontotemporal dementia | NA | BeFree | Detail | |
| <0.001 | Impaired cognition | NA | BeFree | Detail | |
| <0.001 | Nonorganic psychosis | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of prostate | NA | BeFree | Detail | |
| 0.024 | multiple system atrophy | Interestingly, measurements of α-synuclein gene (SNCA) expression in MSA brain t... | BeFree,GAD,LHGDN | 25218777 | Detail |
| 0.024 | multiple system atrophy | We report here that multiple system atrophy (MSA) is caused by a different human... | BeFree,GAD,LHGDN | 26324905 | Detail |
| <0.001 | Pallidoluysian degeneration | NA | BeFree | Detail | |
| <0.001 | Motor symptoms | NA | BeFree | Detail | |
| 0.033 | dementia | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Opiate Addiction | NA | BeFree | Detail | |
| 0.142 | Neurodegenerative Disorders | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | prostate carcinoma | NA | BeFree | Detail | |
| 0.120 | Manganese Poisoning | NA | CTD_human | Detail | |
| <0.001 | breast carcinoma | NA | BeFree | Detail | |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Alzheimer Disease, Early Onset | NA | BeFree | Detail | |
| <0.001 | Frontotemporal Lobar Degeneration | While all four dementia types appear to involve genes associated with tau-pathol... | BeFree | 25567624 | Detail |
| <0.001 | Autosomal Dominant Parkinsonism | NA | BeFree | Detail | |
| <0.001 | spinocerebellar ataxia type 2 | NA | BeFree | Detail | |
| 0.386 | Lewy Body Disease | Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the... | BeFree,CLINVAR,CTD_human,GAD,LHGDN,UNIPROT | 24973356 | Detail |
| 0.005 | Tauopathies | NA | LHGDN | Detail | |
| <0.001 | drug dependence | NA | BeFree | Detail | |
| <0.001 | colorectal cancer | Detection of SNCA and FBN1 methylation in the stool as a biomarker for colorecta... | BeFree | 25802477 | Detail |
| 0.002 | Methamphetamine dependence | NA | GAD | Detail | |
| <0.001 | PARKINSON DISEASE 15, AUTOSOMAL RECESSIVE (disorder) | NA | BeFree | Detail | |
| 0.320 | PARKINSON DISEASE 4, AUTOSOMAL DOMINANT LEWY BODY (disorder) | NA | CLINVAR,CTD_human,MGD | Detail | |
| <0.001 | Plaque, Amyloid | NA | BeFree | Detail | |
| <0.001 | Parkinson disease, late-onset | NA | BeFree | Detail | |
| 0.001 | Parkinson Disease, Familial, Type 1 | NA | BeFree | Detail | |
| <0.001 | adenoma | NA | BeFree | Detail | |
| <0.001 | alcohol use disorder | NA | BeFree | Detail | |
| 0.124 | Alcoholic Intoxication, Chronic | NA | BeFree,CTD_human,LHGDN | Detail | |
| 0.012 | Alzheimer's disease | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | amyloidosis | NA | BeFree,LHGDN | Detail | |
| 0.003 | amyotrophic lateral sclerosis | NA | LHGDN | Detail | |
| <0.001 | rheumatoid arthritis | NA | BeFree | Detail | |
| 0.003 | Astrocytoma | NA | LHGDN | Detail | |
| <0.001 | Malignant neoplasm of breast | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| Detection of SNCA and FBN1 methylation in the stool as a biomarker for colorectal cancer. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| While all four dementia types appear to involve genes associated with tau-pathology and neuroinflamm... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Analysis of alpha-synuclein protein was then performed in ten metastatic tissue samples from the Lun... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Interestingly, measurements of α-synuclein gene (SNCA) expression in MSA brain tissue have not revea... | DisGeNET | Detail |
| We report here that multiple system atrophy (MSA) is caused by a different human prion composed of t... | DisGeNET | Detail |
| An α-synuclein gene (SNCA) polymorphism moderates the association of PTSD symptomatology with hazard... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| PD-L1 and PD-1 protein expression were analysed in 94 clinical cases of small cell carcinomas (61 pu... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Link between the SNCA gene and parkinsonism. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| PD-L1 and PD-1 protein expression were analysed in 94 clinical cases of small cell carcinomas (61 pu... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Interestingly, measurements of α-synuclein gene (SNCA) expression in MSA brain tissue have not revea... | DisGeNET | Detail |
| We report here that multiple system atrophy (MSA) is caused by a different human prion composed of t... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| While all four dementia types appear to involve genes associated with tau-pathology and neuroinflamm... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Detection of SNCA and FBN1 methylation in the stool as a biomarker for colorectal cancer. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- Genome
- hg19
- Position
- chr4:90,621,496-90,759,466
- Variant Type
- snv
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