essential tremor
Information
- Disease name
- essential tremor
- Disease ID
- DOID:4990
- Description
- "A movement disorder that causes involuntary tremors, especially in the hands. It occurs alone without other neurological signs and symptoms." [url:http\://en.wikipedia.org/wiki/Essential_tremor, url:http\://ghr.nlm.nih.gov/condition/essential-tremor]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05122650 | Active, not recruiting | Phase 2 | A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET) | December 6, 2021 | May 31, 2024 |
| NCT05540626 | Active, not recruiting | N/A | RWE Study Utilizing the Cala Trio Device in Patients With Essential Tremor | April 8, 2021 | June 2024 |
| NCT02252380 | Active, not recruiting | N/A | ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders | May 2015 | December 2023 |
| NCT02255929 | Active, not recruiting | N/A | Gamma Knife Radiosurgery for Treatment of Essential Tremor | September 2014 | December 2023 |
| NCT05956223 | Active, not recruiting | N/A | The Development of a System for Measurement of Tremor | November 30, 2023 | June 30, 2025 |
| NCT04074031 | Active, not recruiting | N/A | Transcranial Ultrasound Therapy of Essential Tremor | January 7, 2020 | October 4, 2024 |
| NCT03100474 | Active, not recruiting | Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders: | December 2016 | January 2024 | |
| NCT03560622 | Active, not recruiting | N/A | Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy | September 1, 2018 | December 31, 2021 |
| NCT02289560 | Active, not recruiting | N/A | Continued Access Protocol: ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors | April 2015 | December 2022 |
| NCT04501484 | Active, not recruiting | N/A | Bilateral Essential Tremor Treatment With FUS | July 8, 2020 | December 2025 |
| NCT04112381 | Active, not recruiting | N/A | Bilateral Treatment of Medication Refractory Essential Tremor | June 30, 2020 | June 2023 |
| NCT03305588 | Active, not recruiting | N/A | RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's Disease | December 5, 2017 | December 2025 |
| NCT02649166 | Active, not recruiting | N/A | Responsive Deep Brain Stimulator for Essential Tremor | February 1, 2017 | June 30, 2024 |
| NCT03778060 | Active, not recruiting | N/A | Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study | February 11, 2019 | December 2026 |
| NCT00646451 | Completed | Early Phase 1 | Pregabalin in the Treatment of Essential Tremor | June 2006 | December 2008 |
| NCT05842434 | Completed | N/A | Pilot Study of the Felix System in Patients With Essential Tremor and Parkinson's Tremor | June 6, 2023 | November 29, 2023 |
| NCT00848172 | Completed | Phase 1/Phase 2 | Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor | February 2009 | November 2010 |
| NCT00906412 | Completed | Ventrointermediate Nucleus (VIM DBS) and Working Memory | September 2006 | November 2016 | |
| NCT00998660 | Completed | Phase 4 | RECHARGE Sub-Study to the Implantable Systems Performance Registry (ISPR) | July 2009 | July 2013 |
| NCT01200966 | Completed | Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates | August 30, 2010 | January 4, 2017 | |
| NCT01223144 | Completed | N/A | Decision-making and Emotion Recognition in Essential Tremor | September 2010 | December 2011 |
| NCT01250067 | Completed | N/A | Motor-related Cortical Potential in Patients With Essential Tremor | August 2003 | |
| NCT01304758 | Completed | Phase 1 | ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor | January 2011 | October 2012 |
| NCT01332695 | Completed | Phase 2 | A Pilot Efficacy and Safety Study of ST101 in Essential Tremor | April 2011 | December 2011 |
| NCT01334814 | Completed | N/A | Chronic Versus Intermittent Deep Brain Stimulation for Essential Tremor | January 2002 | January 2010 |
| NCT05480215 | Completed | N/A | Symptomatic Relief of Action Tremor With Cala Trio Using Trio+ Bands | October 7, 2021 | December 16, 2021 |
| NCT05244863 | Completed | The Relationship of Muscle Strength With Functional Skills in Geriatric Individuals With Essential Tremor | March 15, 2020 | March 15, 2021 | |
| NCT01468948 | Completed | Phase 1 | Octanoic Acid for Essential Tremor | October 28, 2011 | July 18, 2012 |
| NCT01534650 | Completed | Movement Disorder Quantification Algorithm Development | February 2012 | January 2016 | |
| NCT01579435 | Completed | N/A | Experimental Therapeutics in Essential Tremor Using Transcranial Direct Current Stimulation | April 2012 | April 2013 |
| NCT05177900 | Completed | N/A | Interphase Gap in Biphasic Stimulation in DBS for ET | December 1, 2021 | January 27, 2022 |
| NCT01602042 | Completed | Adaptive Portable Essential Tremor Monitor | May 2012 | November 2012 | |
| NCT01698450 | Completed | Phase 1 | Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders | November 2012 | December 2013 |
| NCT01705301 | Completed | Neurotransmitter Measurements Using (WINCS) During Deep Brain Stimulation Neurosurgery | January 2010 | July 27, 2017 | |
| NCT05173012 | Completed | Phase 2 | Study to Evaluate SAGE-324 in Participants With Essential Tremor | January 24, 2022 | May 16, 2024 |
| NCT01764815 | Completed | N/A | Evaluation of Directional Stimulation During the Implantation of Deep Brain Stimulation (DBS) Leads | December 2012 | November 2013 |
| NCT01809613 | Completed | Functional Magnetic Resonance Imaging (fMRI) During Deep Brain Stimulation (DBS) to Treat Parkinson's Disease | March 2013 | July 27, 2017 | |
| NCT05157321 | Completed | N/A | Repetitive Transcranial Magnetic Stimulation in Essential Tremors Patients | December 10, 2021 | April 30, 2022 |
| NCT01827904 | Completed | N/A | ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors | May 2013 | February 24, 2021 |
| NCT01932463 | Completed | N/A | ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) for Treatment of Tremor | May 2011 | July 2013 |
| NCT05106816 | Completed | N/A | The Effects of Vibrotactile Stimulation in Patients With Movement Disorders | October 7, 2021 | September 20, 2022 |
| NCT01952678 | Completed | Compare Rates of Agreement Between Clinical Diagnosis and Visual Assessment of DaTscan™ Images in Non-Caucasian and Caucasian Subjects With Parkinson's Disease (PD) or Essential Tremor (ET) | July 30, 2013 | May 2016 | |
| NCT01978080 | Completed | N/A | Continuous Tremor Assessment During Daily Activities | October 2013 | |
| NCT02037217 | Completed | Phase 1 | ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor | February 2011 | January 2014 |
| NCT02052271 | Completed | N/A | Experimental Therapeutics in Essential Tremor Using Cerebellar Transcranial Direct Current Stimulation | June 3, 2014 | March 27, 2018 |
| NCT02067702 | Completed | Limb Cooling in Essential Tremor | October 2014 | January 14, 2019 | |
| NCT02071446 | Completed | Local Fields Potentials Recorded From Deep Brain Stimulating Electrodes | March 2014 | November 29, 2017 | |
| NCT02087046 | Completed | N/A | Deep Brain Stimulation (DBS) for the Suppression of Tremor | October 2005 | December 2017 |
| NCT02111369 | Completed | Phase 4 | Propranolol and Botulinum Toxin for Essential Vocal Tremor | May 2014 | November 2014 |
| NCT02132052 | Completed | Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders (PD), Essential Tremor (ET), Cortical Basal Degeneration (CBD), Multiple Systems Atrophy (MSA), Magnetoencephalography. | November 2013 | May 2014 | |
| NCT02264925 | Completed | N/A | Thalamic LFPs and VIM DBS in Essential Tremor: Correlation, Evolution, and Therapeutic Perspectives | November 2014 | November 19, 2020 |
| NCT02277106 | Completed | Phase 2 | Evaluate SAGE-547 in Participants With Essential Tremor | September 23, 2014 | August 14, 2015 |
| NCT02346409 | Completed | N/A | Cerebello-thalamo-cortical Coupling in Essential Tremor | February 4, 2015 | February 16, 2018 |
| NCT05021991 | Completed | Phase 2 | A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor | October 14, 2021 | February 29, 2024 |
| NCT02443181 | Completed | N/A | Demand-driven Management of Essential Tremor | February 2015 | February 2022 |
| NCT05021978 | Completed | Phase 2 | A Clinical Trial of PRAX-944 in Participants With Essential Tremor | March 3, 2020 | March 24, 2022 |
| NCT02495883 | Completed | Phase 4 | Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response | December 2013 | April 2017 |
| NCT02523807 | Completed | Tremor Monitoring Device | September 2015 | October 30, 2017 | |
| NCT04925622 | Completed | Complex Eye Movements in Parkinson's Disease and Related Movement Disorders | January 4, 2021 | April 15, 2022 | |
| NCT02569021 | Completed | Battery-preserving Stimulation Patterns for Deep Brain Stimulation | May 2014 | September 2016 | |
| NCT02629614 | Completed | N/A | Cala ONE Device for Essential Tremor | April 2016 | November 2016 |
| NCT04880616 | Completed | Phase 2 | Safety, Efficacy, and Tolerability of NBI-827104 for the Treatment of Essential Tremor | April 20, 2021 | June 8, 2022 |
| NCT02668835 | Completed | GADGET-PD Genetic and Digital Diagnosis of Essential Tremor and Parkinson's Disease Trial | November 2015 | April 2019 | |
| NCT04725045 | Completed | N/A | Investigating the Use of Complex Pulse Shapes for DBS in Movement Disorders | February 12, 2019 | April 14, 2022 |
| NCT04720469 | Completed | N/A | A Second Magnetic Resonance Guided Focused Ultrasound Thalamotomy for Essential Tremor | October 5, 2020 | March 18, 2024 |
| NCT02704793 | Completed | N/A | Cerebellar rTMS for Essential Tremor | April 2016 | May 2018 |
| NCT02711995 | Completed | N/A | Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection Augmentation | December 15, 2015 | September 29, 2016 |
| NCT04692844 | Completed | Pathophysiology of Tremor-modulating Mechanisms of Propranolol and Primidone in Essential Tremor | August 28, 2017 | December 31, 2022 | |
| NCT02761707 | Completed | Biomarkers in Neural Disorders | June 2016 | July 16, 2019 | |
| NCT02763865 | Completed | N/A | A Pilot Study to Assess the Effects of Pre-SMA LF-rTMS for the Treatment of Essential Tremor | July 2014 | March 21, 2017 |
| NCT04658641 | Completed | N/A | Characterization of Complex Pulse Shapes in Deep Brain Stimulation for Movement Disorders Using EEG and Local Field Potential Recordings | December 14, 2020 | June 20, 2023 |
| NCT02909907 | Completed | N/A | Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET) | August 2016 | February 28, 2018 |
| NCT02947841 | Completed | N/A | The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients | October 2016 | July 2017 |
| NCT02960243 | Completed | N/A | Deep Brain Stimulation for Voice Tremor: Left, Right, or Both Hemispheres? | August 2016 | December 2020 |
| NCT02978781 | Completed | Phase 2 | A Study to Evaluate SAGE-217 in Participants With Essential Tremor | March 24, 2017 | December 5, 2017 |
| NCT04576676 | Completed | Environmental Epidemiology of Essential Tremor | July 2, 2020 | July 19, 2023 | |
| NCT03027310 | Completed | Clinical and Physiological Studies of Tremor Syndromes | May 5, 2017 | March 23, 2022 | |
| NCT03041714 | Completed | Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor | April 7, 2017 | March 22, 2018 | |
| NCT03051178 | Completed | N/A | Wearable Sensor for Responsive DBS for ET | September 18, 2018 | September 29, 2021 |
| NCT03101241 | Completed | Phase 2 | A Phase 2 RCT Study of CX-8998 for Essential Tremor | August 29, 2017 | July 16, 2018 |
| NCT03152136 | Completed | N/A | A Pilot Study of the Cala ONE Device for Essential Tremor | July 26, 2017 | March 8, 2018 |
| NCT04361955 | Completed | N/A | Modulatory Effects of Deep Brain Stimulation on Cerebral Cortical Activity | January 31, 2020 | August 10, 2023 |
| NCT04305275 | Completed | Phase 2 | A Study to Evaluate the Efficacy, Safety, and Tolerability of SAGE-324 in Participants With Essential Tremor | May 19, 2020 | February 15, 2021 |
| NCT04193527 | Completed | Phase 3 | A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients | June 28, 2020 | December 20, 2021 |
| NCT03805750 | Completed | Phase 1/Phase 2 | Trial of Cannabis for Essential Tremor | January 22, 2019 | November 30, 2020 |
| NCT00016679 | Completed | Phase 1 | 1-Octanol to Treat Essential Tremor | May 2001 | March 2004 |
| NCT00018564 | Completed | Phase 3 | Novel Therapies for Essential Tremor | October 2000 | September 2003 |
| NCT00080366 | Completed | Phase 2 | Octanol to Treat Essential Tremor | March 2004 | March 2007 |
| NCT00102596 | Completed | Phase 2 | Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tremor | January 2005 | September 2009 |
| NCT00223743 | Completed | Phase 2 | A Safety/Efficacy Trial of Zonisamide for Essential Tremor | November 2004 | |
| NCT00236496 | Completed | Phase 3 | A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Treating Tremor of Unknown Cause. | October 2001 | February 2004 |
| NCT00001986 | Completed | Phase 1 | 1-Octanol to Treat Essential Tremor | January 2000 | January 2001 |
| NCT00368199 | Completed | Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes | September 1, 2006 | September 15, 2012 | |
| NCT00439699 | Completed | Phase 4 | A Pilot Clinical Trial Of Memantine for Essential Tremor | February 2007 | December 2009 |
| NCT00584376 | Completed | Phase 4 | Pregabalin (Lyrica) for the Treatment of Essential Tremor | December 2007 | November 2010 |
| NCT00598078 | Completed | Phase 2 | Multiple-dose,Double-blind,Placebo-controlled Study of Sodium Oxybate in Patients With Essential Tremor | December 2007 | December 2008 |
| NCT06314139 | Completed | N/A | Tolerability and Efficacy of Continuous Theta-burst Stimulation for Essential Tremor: A Randomized Study. | September 1, 2022 | June 1, 2023 |
| NCT00620165 | Completed | Phase 1/Phase 2 | Efficacy of Levetiracetam in Essential Tremor | January 2005 | March 2008 |
| NCT03780426 | Completed | Phase 2 | tSMS in Essential Tremor | October 1, 2018 | December 1, 2019 |
| NCT03794661 | Completed | N/A | Evaluation of the Infinity Deep Brain Stimulation Electrode Screening Mode Tool | June 26, 2019 | December 16, 2020 |
| NCT03884231 | Completed | A Post-Market Study Evaluating the Safety of Infinity DBS System With MR Conditional Labeling | April 10, 2019 | August 20, 2021 | |
| NCT03875404 | Completed | N/A | Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor | March 20, 2019 | February 12, 2021 |
| NCT03597100 | Completed | N/A | Prospective Study for Symptomatic Relief of ET With Cala Therapy | December 14, 2018 | May 29, 2019 |
| NCT03638479 | Completed | Utilizing Smart Devices to Identify New Phenotypical Characteristics in Movement Disorders | January 8, 2019 | December 31, 2021 | |
| NCT03688685 | Completed | Phase 2 | A Clinical Study to Evaluate CAD-1883 in Essential Tremor | January 23, 2019 | September 24, 2019 |
| NCT03696420 | Completed | Probabilistic Targeting of the VIM | November 30, 2018 | November 30, 2018 | |
| NCT03760406 | Completed | N/A | Optimization of VIM Targeting in Essential Tremor Surgery | March 18, 2018 | August 29, 2023 |
| NCT02553525 | Enrolling by invitation | N/A | Effects of Stimulation Patterns of Deep Brain Stimulation | June 2, 2016 | September 2026 |
| NCT06349538 | Enrolling by invitation | Identifying Markers of Disease Subtypes and Disease Progression in the Syndrome of Essential Tremor | April 4, 2024 | April 30, 2034 | |
| NCT05976074 | Enrolling by invitation | N/A | A Study of Wearable Device in Essential Tremor Patients | July 7, 2023 | August 2024 |
| NCT02320266 | Enrolling by invitation | Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery | December 2014 | December 2025 | |
| NCT06428526 | Not yet recruiting | N/A | Impact of Sensory Electrical Stimulation on Sensation and Tremor | July 1, 2024 | October 1, 2028 |
| NCT04727658 | Not yet recruiting | Phase 2 | Linac FRACtionated Radiosurgical THALamotomie in Tremors (FRACTHAL) | March 2021 | March 2027 |
| NCT05089786 | Not yet recruiting | N/A | Echo-Focusing in Patients With Treatment-Resistant Neurologic and Psychiatric Indications (EF001) | December 31, 2022 | February 28, 2025 |
| NCT05170022 | Not yet recruiting | Clinical Profile in Patients With Essential Tremors | March 1, 2022 | January 1, 2025 | |
| NCT05795218 | Not yet recruiting | directSTIM™ Deep Brain Stimulation System Post-Market Clinical Follow-up Study on Essential Tremor | October 2023 | July 2025 | |
| NCT05958030 | Not yet recruiting | N/A | GyroGlove Use in Essential Tremor Patients | June 2024 | August 2024 |
| NCT06036368 | Not yet recruiting | N/A | Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's Disease and Essential Tremor | September 15, 2023 | June 30, 2024 |
| NCT06325852 | Not yet recruiting | N/A | Directional Bilateral Thalamic Patterned Stimulation (Chronos) | August 1, 2024 | January 1, 2027 |
| NCT06352268 | Not yet recruiting | Lesioning Procedures for Movement Disorders | April 15, 2024 | December 31, 2028 | |
| NCT06378619 | Not yet recruiting | Tapping Test and the Archimedean Spiral for the Differential Diagnosis of Tremor. Machine Learning Approach | May 2024 | June 2025 | |
| NCT06397391 | Not yet recruiting | N/A | Nonlinear Absorber in Essential Tremor Treatment | June 2024 | December 2025 |
| NCT06403280 | Not yet recruiting | N/A | The Effect of Alcohol on Common Tremor Syndromes | May 2024 | April 2025 |
| NCT04198246 | Recruiting | Chinese ET Registry (CETR) | January 1, 2019 | December 31, 2028 | |
| NCT04212780 | Recruiting | N/A | Dual Lead Thalamic Deep Brain Recording (DBR)-DBS Interface for Closed Loop Control of Severe Essential Tremor | December 24, 2019 | August 31, 2025 |
| NCT04231487 | Recruiting | Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders | June 27, 2019 | December 31, 2022 | |
| NCT04502550 | Recruiting | Brain Networks and Consciousness | October 15, 2020 | August 15, 2025 | |
| NCT04581941 | Recruiting | Deep Brain Stimulation Effects in Essential Tremor | December 5, 2020 | December 30, 2025 | |
| NCT02712515 | Recruiting | The Motor Network in Essential Tremor: Mechanisms of Therapy | March 2016 | November 3, 2028 | |
| NCT04748640 | Recruiting | Phase 2/Phase 3 | Bilateral Essential Tremor Treatment With Gamma Knife | June 8, 2021 | October 2026 |
| NCT04758624 | Recruiting | N/A | Elucidating the Temporality of Structural and Functional Connectivity Changes in Essential Tremor After Successful Deep Brain Stimulation to the Dentato-rubro-thalamic Tract | December 4, 2021 | August 31, 2026 |
| NCT04957095 | Recruiting | Motor Network Physiology | February 18, 2022 | December 31, 2024 | |
| NCT05101161 | Recruiting | N/A | Neurofeedback Using Implanted Deep Brain Stimulation Electrodes | September 23, 2021 | September 23, 2026 |
| NCT01734122 | Recruiting | Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor | February 21, 2013 | February 2028 | |
| NCT01581580 | Recruiting | N/A | Deep Brain Stimulation Surgery for Movement Disorders | August 17, 2011 | December 1, 2029 |
| NCT05214222 | Recruiting | Phase 2 | Penpulimab Plus Chemotherapy With/Without Anlotinib for Patients With Advanced Esophageal Squamous Cell Carcinoma | September 2, 2022 | July 1, 2024 |
| NCT05308368 | Recruiting | N/A | Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation | February 11, 2020 | January 1, 2100 |
| NCT05317390 | Recruiting | N/A | Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia | June 1, 2022 | April 30, 2027 |
| NCT05366751 | Recruiting | Phase 2/Phase 3 | A Study to Evaluate the Long-term Safety and Tolerability of SAGE-324 in Participants With Essential Tremor | June 13, 2022 | September 2027 |
| NCT05475340 | Recruiting | Early Phase 1 | Open Label Study for the Use of Transcranial Ultrasound Treatment of Tremor | July 13, 2022 | August 13, 2024 |
| NCT05535556 | Recruiting | Comparison of the Electric Plasma Surgical Tool "PlasmaBlade" for Replacement of the Deep Brain Stimulation (DBS) Devices With Conventional Surgery | July 14, 2022 | February 14, 2024 | |
| NCT05671848 | Recruiting | N/A | Electroclinical Correlates in Essential Tremor | May 3, 2023 | March 1, 2025 |
| NCT05769933 | Recruiting | Bridging Gaps in the Neuroimaging Puzzle: New Ways to Image Brain Anatomy and Function in Health and Disease Using Electroencephalography and 7 Tesla Magnetic Resonance Imaging | September 21, 2022 | August 31, 2024 | |
| NCT06331052 | Recruiting | N/A | 3-D Tractography FUS Ablation for Essential Tremor | February 28, 2024 | February 28, 2028 |
| NCT05897775 | Recruiting | Phase 1 | Coordinated Reset Deep Brain Stimulation for Essential Tremor | September 11, 2023 | June 30, 2028 |
| NCT05909839 | Recruiting | The STEREO-DBS ET Study: 7-Tesla MRI Brain Network Analysis for Deep Brain Stimulation in Essential Tremor | June 9, 2023 | June 9, 2033 | |
| NCT06343285 | Recruiting | N/A | Upper Limb Tremor Reduction in Essential Tremor Patients | January 1, 2024 | June 2024 |
| NCT05965960 | Recruiting | N/A | Investigating LFP Correlates of TUS in Patients With Movement Disorders | May 18, 2023 | June 1, 2024 |
| NCT05968976 | Recruiting | N/A | Multicentre RCT of Awake Versus Asleep Tractography Based DBS for ET | September 1, 2023 | July 1, 2028 |
| NCT00575081 | Recruiting | Physiological Brain Atlas Development | August 2006 | July 2025 | |
| NCT06087276 | Recruiting | Phase 3 | Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET) | November 2, 2023 | April 2025 |
| NCT06145932 | Recruiting | N/A | Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor | November 7, 2023 | December 31, 2026 |
| NCT06235190 | Recruiting | N/A | Assessment of the Safety and Efficacy of the Felix NeuroAI Wristband in Essential Tremor | February 27, 2024 | November 2025 |
| NCT06293638 | Recruiting | Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor | March 25, 2024 | December 31, 2026 | |
| NCT03832712 | Recruiting | N/A | The Swedish Essential Tremor (SWEET) Trial | June 30, 2018 | January 30, 2027 |
| NCT03811405 | Recruiting | N/A | Physiology, Imaging and Modeling of Essential Tremor | April 1, 2021 | June 30, 2024 |
| NCT03984643 | Recruiting | N/A | Algorithms for Programming DBS Systems for ET | October 1, 2019 | December 31, 2025 |
| NCT03992625 | Recruiting | Clinical Outcomes for Deep Brain Stimulation | January 3, 2011 | January 1, 2030 | |
| NCT04032470 | Recruiting | Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET) | October 23, 2019 | December 2028 | |
| NCT04071847 | Recruiting | Abbott DBS Post-Market Study of Outcomes for Indications Over Time | November 26, 2019 | September 2030 | |
| NCT03664609 | Recruiting | Deep Brain Stimulation (DBS) Retrospective Outcomes Study | March 12, 2019 | December 2028 | |
| NCT04265209 | Recruiting | Phase 3 | [18F] LBT-999 PET Compared to [123I]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tremor | December 1, 2021 | December 2024 |
| NCT04286308 | Recruiting | N/A | Cortical-Basal Ganglia Speech Networks | October 1, 2020 | February 2026 |
| NCT03465761 | Recruiting | N/A | Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor | January 3, 2019 | December 2023 |
| NCT04501133 | Recruiting | N/A | Sensory-specific Peripheral Stimulation for Tremor Management | September 1, 2020 | December 2025 |
| NCT02894567 | Terminated | N/A | Evaluation of Directional Recording and Stimulation Using spiderSTN | September 2016 | February 2017 |
| NCT03769961 | Terminated | Ataxia in Essential Tremor: Describing the Differences Between Disease Process and Treatment Effect | December 1, 2018 | September 14, 2020 | |
| NCT00655278 | Terminated | Phase 2 | T2000 in Essential Tremor - Open Label Continuation | August 2007 | December 2009 |
| NCT02678429 | Terminated | N/A | Atlas Predicted DBS Settings in Essential Tremor | September 2016 | November 19, 2021 |
| NCT00802191 | Terminated | WiiMote Game Controller as a Device to Study Movement Disorders | August 2007 | August 2014 | |
| NCT00321087 | Terminated | Phase 2 | A Study of T2000 in Essential Tremor | August 2006 | December 2007 |
| NCT03253991 | Terminated | N/A | A Study to Evaluate the Effectiveness and Safety of ExAblate MRgFUS on Essential Tremor | November 17, 2014 | February 2, 2023 |
| NCT03487705 | Terminated | N/A | Essential Tremor in Children and Adolescent | July 1, 2018 | July 2, 2021 |
| NCT05214313 | Terminated | N/A | Impact of a Standardized Music Therapy Protocol on the Quality of Life of Patients With Abnormal Movements Treated With Continuous Electrical Neuromodulation | March 3, 2022 | September 14, 2023 |
| NCT03025529 | Terminated | N/A | Transcranial Stimulation for Essential Tremor | February 2015 | November 28, 2016 |
| NCT05096572 | Terminated | N/A | DBS of Posterior Subthalamic Area (PSA) and Ventral Intermediate Nucleus (VIM) in Essential Tremor (ET) | November 30, 2021 | October 30, 2023 |
| NCT00616343 | Terminated | N/A | Zonisamide in the Treatment of Essential Tremor | June 2003 | December 2012 |
| NCT04260971 | Unknown status | N/A | Cyclic Deep Brain Stimulation in Essential Tremor | February 25, 2020 | December 31, 2022 |
| NCT01446939 | Unknown status | Imaging in the Diagnosis of Parkinson's Disease and Essential Tremor | October 2012 | July 2014 | |
| NCT03795935 | Unknown status | N/A | Relief From Side Effects: Clinical Use of Electrodes With Direction | September 17, 2018 | August 1, 2019 |
| NCT03269201 | Unknown status | Brain Network Activation in Patients With Movement Disorders | March 1, 2019 | September 15, 2022 | |
| NCT05362448 | Unknown status | N/A | Neurophysiologic Assessment of ET Patients Treated by Vim DBS | May 23, 2022 | November 1, 2022 |
| NCT04509349 | Unknown status | N/A | Alternating Current Stimulation for Essential Tremor | October 1, 2020 | August 2022 |
| NCT02692183 | Unknown status | Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease Before and After MR-guided Focused Ultrasound Thalamotomy for Tremor | February 2016 | January 2019 | |
| NCT03952117 | Unknown status | N/A | Transcranial Direct Current Stimulation of the Motor Cortex in Essential Tremor | July 19, 2019 | October 2021 |
| NCT04828798 | Unknown status | N/A | Directional Versus Nondirectional DBS for ET | April 1, 2021 | February 8, 2024 |
| NCT02668146 | Unknown status | Phase 2 | An Efficacy/Safety Study of Perampanel for Reducing Essential Tremor | October 2015 | June 2017 |
| NCT02551848 | Unknown status | Phase 2 | Kinematic-based BoNT-A Injections for Bilateral ET | August 2014 | December 2021 |
| NCT02491554 | Unknown status | N/A | Deep braIn Stimulation for Tremor TractographIC Versus Traditional | August 2015 | June 30, 2022 |
| NCT01909531 | Unknown status | Deep Brain Stimulation (DBS) Data Base Study | April 2013 | December 31, 2023 | |
| NCT00608231 | Withdrawn | Phase 2/Phase 3 | Dexmedetomidine Effects on Microelectrode Recording in Deep Brain Stimulation | January 2008 | January 2012 |
| NCT01441284 | Withdrawn | Phase 3 | Efficacy of Pramipexole Extended Release in the Treatment of Essential Tremor | December 2017 | December 2018 |
| NCT00634478 | Withdrawn | N/A | Pre-lemniscal Radiation Deep Brain Stimulation for ET | October 2008 | January 19, 2011 |
| NCT01940406 | Withdrawn | N/A | The Essential Tremor (ET) and Parkinson Disease (PD) Tremor Acute Stimulation Study | October 2013 | December 2013 |
| NCT04283812 | Withdrawn | N/A | New Stereotactic Frame System for Neurosurgery | January 2023 | June 2023 |
| NCT01820390 | Withdrawn | Optimizing DBS Electrode Placement and Programming | March 2013 | December 2015 | |
| NCT05387642 | Withdrawn | Phase 2 | A Clinical Trial of PRAX-114 in Participants With Essential Tremor | April 5, 2022 | June 30, 2022 |
| NCT06312800 | Withdrawn | Phase 2 | Acamprosate and Methazolamide for Essential Tremor | March 2016 | December 2017 |
| NCT05381688 | Withdrawn | VIM DBS Respiratory Modulation: N-of-1 Trial | September 9, 2021 | July 31, 2022 | |
| NCT02418858 | Withdrawn | N/A | Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor | February 2015 | June 2017 |
- Disase is a (Disease Ontology)
- DOID:480
- Cross Reference ID (Disease Ontology)
- GARD:5910
- Cross Reference ID (Disease Ontology)
- ICD10CM:G25.0
- Cross Reference ID (Disease Ontology)
- MESH:D020329
- Cross Reference ID (Disease Ontology)
- MIM:PS190300
- Cross Reference ID (Disease Ontology)
- NCI:C182453
- Cross Reference ID (Disease Ontology)
- ORDO:862
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:192839001
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0270736
- Exact Synonym (Disease Ontology)
- benign essential tremor
- Exact Synonym (Disease Ontology)
- essential hereditary tremor
- Exact Synonym (Disease Ontology)
- shaky hand syndrome
- ICD10 preferred id (Insert disease from ICD10)
- D0005307
- ICD10 class code (Insert disease from ICD10)
- G25.0
- MeSH unique ID (MeSH (Medical Subject Headings))
- D020329