chr3:113846427:> Detail (hg19)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr3:113,846,427-113,918,254 |
| hg38 | chr3:114,127,580-114,199,407 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | Chorea | NA | BeFree | Detail | |
| 0.003 | cocaine abuse | NA | BeFree,GAD | Detail | |
| 0.120 | Cognition Disorders | NA | CTD_human | Detail | |
| <0.001 | Obsessive-Compulsive Personality | NA | BeFree | Detail | |
| 0.003 | Delirium | NA | BeFree,GAD | Detail | |
| <0.001 | Delusions | NA | BeFree | Detail | |
| <0.001 | Presenile dementia | NA | BeFree | Detail | |
| 0.003 | Mental Depression | NA | BeFree,GAD | Detail | |
| 0.001 | depressive disorder | NA | BeFree | Detail | |
| <0.001 | Diabetic Nephropathy | NA | BeFree | Detail | |
| <0.001 | Drug abuse | NA | BeFree | Detail | |
| 0.007 | Dyskinetic syndrome | NA | BeFree,LHGDN | Detail | |
| 0.122 | Dyskinesia, Drug-Induced | NA | CTD_human,GAD | Detail | |
| 0.002 | fibromyalgia | NA | GAD | Detail | |
| 0.120 | Gambling | NA | CTD_human | Detail | |
| 0.001 | Atrial Septal Defects | These findings support a relationship between DRD3 gene SNPs, striatum and stere... | BeFree | 25792691 | Detail |
| <0.001 | heroin dependence | NA | BeFree | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| <0.001 | Hodgkin Disease | NA | BeFree | Detail | |
| <0.001 | Huntington disease | NA | BeFree | Detail | |
| 0.122 | Hyperalgesia | NA | CTD_human,GAD | Detail | |
| 0.080 | Hypertensive disease | NA | RGD | Detail | |
| 0.125 | Disruptive, Impulse Control, and Conduct Disorders | NA | CTD_human,GAD | Detail | |
| <0.001 | Kidney Diseases | NA | BeFree | Detail | |
| 0.002 | Lymphoma, Non-Hodgkin | NA | GAD | Detail | |
| 0.002 | Marijuana Abuse | NA | GAD | Detail | |
| 0.121 | Movement Disorders | NA | BeFree,CTD_human | Detail | |
| 0.002 | multiple sclerosis | NA | GAD | Detail | |
| <0.001 | nicotine dependence | Role of nicotine dependence in the association between the dopamine receptor gen... | BeFree | 24927283 | Detail |
| 0.003 | obsessive-compulsive disorder | NA | BeFree,GAD | Detail | |
| <0.001 | Ovarian Diseases | NA | BeFree | Detail | |
| 0.002 | Pain, Intractable | NA | GAD | Detail | |
| 0.002 | panic disorder | NA | GAD | Detail | |
| 0.024 | Parkinson disease | NA | BeFree,GAD | Detail | |
| 0.003 | Personality Disorders | NA | BeFree,GAD | Detail | |
| 0.005 | Psychoses, Substance-Induced | NA | GAD | Detail | |
| 0.004 | Psychotic Disorders | NA | BeFree,GAD | Detail | |
| <0.001 | schizoaffective disorder | NA | BeFree | Detail | |
| 0.264 | schizophrenia | The dopamine D3 receptor (DRD3) gene has been implicated in schizophrenia, autis... | BeFree,CTD_human,GAD,LHGDN | 25158632 | Detail |
| 0.264 | schizophrenia | Antipsychotic haloperidol binding to the human dopamine D3 receptor: beyond dock... | BeFree,CTD_human,GAD,LHGDN | 25181639 | Detail |
| 0.264 | schizophrenia | Significant association between DRD3 gene body methylation and schizophrenia. | BeFree,CTD_human,GAD,LHGDN | 25262640 | Detail |
| 0.264 | schizophrenia | Taken together, the results from the present study suggest that an interaction b... | BeFree,CTD_human,GAD,LHGDN | 25264289 | Detail |
| <0.001 | Residual schizophrenia | NA | BeFree | Detail | |
| 0.200 | Seizures | NA | CTD_human,RGD | Detail | |
| <0.001 | Stereotyped Behavior | These findings support a relationship between DRD3 gene SNPs, striatum and stere... | BeFree | 25792691 | Detail |
| <0.001 | post-traumatic stress disorder | The dopamine D3 receptor gene and posttraumatic stress disorder. | BeFree | 25158632 | Detail |
| 0.001 | substance dependence | NA | BeFree | Detail | |
| <0.001 | Substance Use Disorders | The dopamine D3 receptor (DRD3) gene has been implicated in schizophrenia, autis... | BeFree | 25158632 | Detail |
| 0.005 | Tobacco use disorder | NA | GAD | Detail | |
| <0.001 | Tremor | NA | BeFree | Detail | |
| 0.001 | Unipolar Depression | Role of nicotine dependence in the association between the dopamine receptor gen... | BeFree | 24927283 | Detail |
| 0.002 | Weight Gain | NA | GAD | Detail | |
| <0.001 | Agitation | NA | BeFree | Detail | |
| 0.005 | Alcohol abuse | NA | BeFree,GAD | Detail | |
| 0.032 | lingual-facial-buccal dyskinesia | NA | BeFree,GAD | Detail | |
| 0.005 | Akathisia, Drug-Induced | NA | GAD | Detail | |
| <0.001 | Motor Disorders | NA | BeFree | Detail | |
| <0.001 | Recurrent depression | NA | BeFree | Detail | |
| 0.001 | Chronic schizophrenia | NA | BeFree | Detail | |
| <0.001 | Psychiatric symptom | NA | BeFree | Detail | |
| 0.002 | Personality Traits | NA | GAD | Detail | |
| <0.001 | Extrapyramidal sign | NA | BeFree | Detail | |
| <0.001 | Resting Tremor | NA | BeFree | Detail | |
| 0.120 | Amphetamine-Related Disorders | NA | CTD_human | Detail | |
| 0.125 | Cocaine-Related Disorders | NA | CTD_human,GAD | Detail | |
| <0.001 | Bipolar II disorder | NA | BeFree | Detail | |
| <0.001 | age related macular degeneration | This ligand-to-targetto DNA sequence variant-to disease approach provided guidan... | BeFree | 25109799 | Detail |
| 0.080 | Parkinsonian Disorders | NA | RGD | Detail | |
| <0.001 | generalized anxiety disorder | NA | BeFree | Detail | |
| <0.001 | Common Migraine | NA | BeFree | Detail | |
| <0.001 | Impaired cognition | NA | BeFree | Detail | |
| 0.001 | Nonorganic psychosis | NA | BeFree | Detail | |
| 0.001 | Abnormal involuntary movement | NA | BeFree | Detail | |
| 0.120 | Hyperactive behavior | NA | CTD_human | Detail | |
| <0.001 | Developmental delay (disorder) | NA | BeFree | Detail | |
| <0.001 | dementia | NA | BeFree | Detail | |
| 0.003 | Opiate Addiction | NA | BeFree,GAD | Detail | |
| 0.003 | Mood Disorders | NA | BeFree,GAD | Detail | |
| 0.001 | Nonorganic psychosis | In this first phase of the project, the objective was to investigate the distrib... | BeFree | 19142409 | Detail |
| <0.001 | Bipolar II disorder | We provide initial evidence that the BDNF Val66Met and DRD3 Ser9Gly genotypes in... | BeFree | 22877924 | Detail |
| 0.004 | Psychotic Disorders | In this first phase of the project, the objective was to investigate the distrib... | BeFree | 19142409 | Detail |
| 0.264 | schizophrenia | Could HTR2A T102C and DRD3 Ser9Gly predict clinical improvement in patients with... | BeFree | 17924589 | Detail |
| 0.032 | lingual-facial-buccal dyskinesia | The 9Gly-variant of the dopamine D3 receptor, the 102C-variant, but not the His4... | BeFree | 15861931 | Detail |
| 0.037 | Tardive Dyskinesia | The 9Gly-variant of the dopamine D3 receptor, the 102C-variant, but not the His4... | BeFree | 15861931 | Detail |
| <0.001 | cocaine dependence | NA | BeFree | Detail | |
| <0.001 | breast carcinoma | NA | BeFree | Detail | |
| 0.037 | Tardive Dyskinesia | NA | BeFree,GAD | Detail | |
| <0.001 | Substance abuse problem | NA | BeFree | Detail | |
| 0.002 | Sleep Disorders | NA | GAD | Detail | |
| <0.001 | Adult attention deficit hyperactivity disorder | NA | BeFree | Detail | |
| <0.001 | Psychotic symptom | NA | BeFree | Detail | |
| 0.009 | attention deficit hyperactivity disorder | NA | BeFree,GAD | Detail | |
| 0.004 | major depressive disorder | Role of nicotine dependence in the association between the dopamine receptor gen... | BeFree,GAD | 24927283 | Detail |
| 0.002 | Methamphetamine abuse | NA | GAD | Detail | |
| 0.001 | drug dependence | NA | BeFree | Detail | |
| 0.001 | Autism Spectrum Disorders | DRD3 gene and striatum in autism spectrum disorder. | BeFree | 25792691 | Detail |
| 0.002 | colorectal cancer | NA | GAD | Detail | |
| <0.001 | Geographic Atrophy | This ligand-to-targetto DNA sequence variant-to disease approach provided guidan... | BeFree | 25109799 | Detail |
| 0.004 | MAJOR AFFECTIVE DISORDER 2 | NA | BeFree,GAD | Detail | |
| 0.004 | MAJOR AFFECTIVE DISORDER 1 | NA | BeFree,GAD | Detail | |
| 0.120 | Tremor, hereditary essential, 1 | NA | CTD_human | Detail | |
| 0.004 | MAJOR AFFECTIVE DISORDER 4 | NA | BeFree,GAD | Detail | |
| 0.004 | MAJOR AFFECTIVE DISORDER 5 | NA | BeFree,GAD | Detail | |
| 0.004 | MAJOR AFFECTIVE DISORDER 6 | NA | BeFree,GAD | Detail | |
| 0.004 | Major affective disorder 7 | NA | BeFree,GAD | Detail | |
| 0.004 | MAJOR AFFECTIVE DISORDER 8 | NA | BeFree,GAD | Detail | |
| 0.004 | MAJOR AFFECTIVE DISORDER 9 | NA | BeFree,GAD | Detail | |
| 0.002 | Weight Gain Adverse Event | NA | GAD | Detail | |
| <0.001 | Mild dementia | NA | BeFree | Detail | |
| <0.001 | Alcohol Withdrawal Delirium | NA | BeFree | Detail | |
| 0.010 | Alcoholic Intoxication, Chronic | NA | BeFree,GAD,LHGDN | Detail | |
| 0.008 | Alzheimer's disease | NA | BeFree,GAD | Detail | |
| 0.082 | Amnesia | NA | GAD,RGD | Detail | |
| <0.001 | anorexia nervosa | NA | BeFree | Detail | |
| <0.001 | anovulation | NA | BeFree | Detail | |
| <0.001 | Anxiety Disorders | NA | BeFree | Detail | |
| 0.125 | autistic disorder | As DRD3 receptors are relatively overexpressed in the striatum, we investigated ... | BeFree,CTD_human,GAD | 25792691 | Detail |
| 0.120 | Basal Ganglia Diseases | NA | CTD_human | Detail | |
| 0.001 | Mental disorders | Investigation of the genetic interaction between BDNF and DRD3 genes in suicidic... | BeFree | 25264289 | Detail |
| 0.023 | bipolar disorder | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | Malignant neoplasm of breast | NA | BeFree,GAD | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These findings support a relationship between DRD3 gene SNPs, striatum and stereotyped behaviour in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major dep... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The dopamine D3 receptor (DRD3) gene has been implicated in schizophrenia, autism, and substance use... | DisGeNET | Detail |
| Antipsychotic haloperidol binding to the human dopamine D3 receptor: beyond docking through QM/MM re... | DisGeNET | Detail |
| Significant association between DRD3 gene body methylation and schizophrenia. | DisGeNET | Detail |
| Taken together, the results from the present study suggest that an interaction between BDNF and DRD3... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These findings support a relationship between DRD3 gene SNPs, striatum and stereotyped behaviour in ... | DisGeNET | Detail |
| The dopamine D3 receptor gene and posttraumatic stress disorder. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The dopamine D3 receptor (DRD3) gene has been implicated in schizophrenia, autism, and substance use... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major dep... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| This ligand-to-targetto DNA sequence variant-to disease approach provided guidance on rational desig... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In this first phase of the project, the objective was to investigate the distribution of four candid... | DisGeNET | Detail |
| We provide initial evidence that the BDNF Val66Met and DRD3 Ser9Gly genotypes interact only in bipol... | DisGeNET | Detail |
| In this first phase of the project, the objective was to investigate the distribution of four candid... | DisGeNET | Detail |
| Could HTR2A T102C and DRD3 Ser9Gly predict clinical improvement in patients with acutely exacerbated... | DisGeNET | Detail |
| The 9Gly-variant of the dopamine D3 receptor, the 102C-variant, but not the His452Tyr polymorphism o... | DisGeNET | Detail |
| The 9Gly-variant of the dopamine D3 receptor, the 102C-variant, but not the His452Tyr polymorphism o... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major dep... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| DRD3 gene and striatum in autism spectrum disorder. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| This ligand-to-targetto DNA sequence variant-to disease approach provided guidance on rational desig... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| As DRD3 receptors are relatively overexpressed in the striatum, we investigated whether striatal vol... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psyc... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386602118 dbSNP
- Genome
- hg19
- Position
- chr3:113,846,427-113,918,254
- Variant Type
- snv
Genome browser