chr6:35607571:T>C Detail (hg19) (FKBP5)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr6:35,607,571-35,607,571 |
hg38 | chr6:35,639,794-35,639,794 View the variant detail on this assembly version. |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_004117.3:c.106-2636A>G | |
NM_001145775.2:c.106-2636A>G | ||
NM_001145776.1:c.106-2636A>G |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
JP | HGVD:[No Data.] |
ToMMo:0.773 | |
NCBN:[No Data.] | |
NCBN(Hondo):[No Data.] | |
NCBN(Ryukyu):[No Data.] | |
East asia | ExAC:[No Data.] |
Prediction
ClinVar
Clinical Significance | Likely risk allele |
Review star | ![]() |
Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
---|---|---|---|---|---|
Likely risk allele | no assertion criteria provided | post-traumatic stress disorder |
![]() |
Detail |
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.001 | child abuse behavior | FKBP5 (rs1360780) and CRHR1 (rs12944712) polymorphisms significantly interacted ... | BeFree | 24099078 | Detail |
0.001 | child abuse behavior | FKBP5 (rs1360780) and CRHR1 (rs12944712) polymorphisms significantly interacted ... | BeFree | 24099078 | Detail |
0.127 | major depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.082 | depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.018 | Mental Depression | The FKBP5 rs1360780 polymorphism is associated with plasma cortisol and FKBP5 mR... | BeFree | 25522420 | Detail |
0.085 | post-traumatic stress disorder | As FKBP5 single-nucleotide polymorphism rs1360780 has a putative functional role... | BeFree | 24959896 | Detail |
0.026 | Mental Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.002 | Unipolar Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.013 | Mental Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.006 | depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.088 | depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.018 | Mental Depression | This study revealed interactions between physical abuse and rs1360780 of the FKB... | BeFree | 21654733 | Detail |
0.126 | major depressive disorder | In the present study, we investigated whether the FKBP5 polymorphism rs1360780 a... | BeFree | 25522420 | Detail |
0.018 | Mental Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
<0.001 | heroin dependence | Fourteen SNPs showed nominally significant association with heroin addiction (p ... | BeFree | 24766650 | Detail |
0.087 | depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.002 | depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.208 | depressive disorder | Polymorphisms in the FK506 binding protein 5 (FKBP5) gene have been shown to inf... | BeFree | 25522420 | Detail |
0.004 | Unipolar Depression | In the present study, we investigated whether the FKBP5 polymorphism rs1360780 a... | BeFree | 25522420 | Detail |
<0.001 | Stress, Psychological | The purpose of this study was to examine whether FKBP5 rs1360780 moderates relat... | BeFree | 25462914 | Detail |
0.003 | major depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.020 | Mental Depression | Polymorphisms in the FK506 binding protein 5 (FKBP5) gene have been shown to inf... | BeFree | 25522420 | Detail |
0.004 | Unipolar Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.020 | Mental Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.005 | Mental disorders | The common single nucleotide polymorphism (SNP) rs1360780 (C/T) of the FK506 Bin... | BeFree | 25331639 | Detail |
<0.001 | Stress, Psychological | It has been reported that a C/T single nucleotide polymorphism in the intron 2 o... | BeFree | 20849924 | Detail |
0.007 | post-traumatic stress disorder | The common single nucleotide polymorphism (SNP) rs1360780 (C/T) of the FK506 Bin... | BeFree | 25331639 | Detail |
0.005 | Mental disorders | The FKBP5 gene single nucleotide polymorphisms (SNP), rs1360780, has been found ... | BeFree | 22825419 | Detail |
0.006 | depressive disorder | This study revealed interactions between physical abuse and rs1360780 of the FKB... | BeFree | 21654733 | Detail |
0.009 | depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.033 | Mental Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.006 | depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.038 | Mental Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.009 | Mental Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.043 | Mental Depression | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.007 | depressive disorder | To investigate the possible relationship between genetic risk factors and depres... | BeFree | 23157339 | Detail |
0.006 | depressive disorder | The FKBP5 rs1360780 polymorphism is associated with plasma cortisol and FKBP5 mR... | BeFree | 25522420 | Detail |
0.003 | major depressive disorder | The single nucleotide polymorphisms FKBP5:rs1360780, BDNF:rs6265 (Val66Met), P2R... | BeFree | 20226536 | Detail |
0.003 | Unipolar Depression | The single nucleotide polymorphisms FKBP5:rs1360780, BDNF:rs6265 (Val66Met), P2R... | BeFree | 20226536 | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NM_004117.4(FKBP5):c.106-2636A>G AND Post-traumatic stress disorder | ClinVar | Detail |
FKBP5 (rs1360780) and CRHR1 (rs12944712) polymorphisms significantly interacted with child abuse and... | DisGeNET | Detail |
FKBP5 (rs1360780) and CRHR1 (rs12944712) polymorphisms significantly interacted with child abuse and... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
The FKBP5 rs1360780 polymorphism is associated with plasma cortisol and FKBP5 mRNA expression after ... | DisGeNET | Detail |
As FKBP5 single-nucleotide polymorphism rs1360780 has a putative functional role in the regulation o... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
This study revealed interactions between physical abuse and rs1360780 of the FKBP5 gene, confirming ... | DisGeNET | Detail |
In the present study, we investigated whether the FKBP5 polymorphism rs1360780 and lifetime history ... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
Fourteen SNPs showed nominally significant association with heroin addiction (p < 0.05), includin... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
Polymorphisms in the FK506 binding protein 5 (FKBP5) gene have been shown to influence glucocorticoi... | DisGeNET | Detail |
In the present study, we investigated whether the FKBP5 polymorphism rs1360780 and lifetime history ... | DisGeNET | Detail |
The purpose of this study was to examine whether FKBP5 rs1360780 moderates relations between differe... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
Polymorphisms in the FK506 binding protein 5 (FKBP5) gene have been shown to influence glucocorticoi... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
The common single nucleotide polymorphism (SNP) rs1360780 (C/T) of the FK506 Binding Protein 5 (FKBP... | DisGeNET | Detail |
It has been reported that a C/T single nucleotide polymorphism in the intron 2 of FKBP5 gene (rs1360... | DisGeNET | Detail |
The common single nucleotide polymorphism (SNP) rs1360780 (C/T) of the FK506 Binding Protein 5 (FKBP... | DisGeNET | Detail |
The FKBP5 gene single nucleotide polymorphisms (SNP), rs1360780, has been found to modulate GC sensi... | DisGeNET | Detail |
This study revealed interactions between physical abuse and rs1360780 of the FKBP5 gene, confirming ... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... | DisGeNET | Detail |
The FKBP5 rs1360780 polymorphism is associated with plasma cortisol and FKBP5 mRNA expression after ... | DisGeNET | Detail |
The single nucleotide polymorphisms FKBP5:rs1360780, BDNF:rs6265 (Val66Met), P2RX7:2230912 (Gln460Ar... | DisGeNET | Detail |
The single nucleotide polymorphisms FKBP5:rs1360780, BDNF:rs6265 (Val66Met), P2RX7:2230912 (Gln460Ar... | DisGeNET | Detail |
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- Genome
- hg19
- Position
- chr6:35,607,571-35,607,571
- Variant Type
- snv
- Reference Allele
- T
- Alternative Allele
- C
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs1360780
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.7728
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 12952
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16760
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