Annotation Detail
Information
- Associated Genes
- FKBP5
- Associated Variants
-
GALR1 p.Ser334Asn (p.S334N)
(
ENST00000299727.5 )
FKBP5 c.106-2636A>G ( ENST00000357266.9, ENST00000536438.5, ENST00000539068.5, ENST00000542713.1 )
GALR1 p.Ser334Asn (p.S334N) ( ENST00000299727.5 )
FKBP5 c.106-2636A>G ( ENST00000357266.9, ENST00000536438.5, ENST00000539068.5, ENST00000542713.1 ) - Associated Disease
- heroin dependence
- Source Database
- DisGeNET
- Description
- Fourteen SNPs showed nominally significant association with heroin addiction (p < 0.05), including the African-specific, missense SNP rs5376 (Asn334Ser) in the galanin receptor type 1 gene (GALR1) and the functional FKBP5 intronic SNP rs1360780.
- Pubmed
- 24766650
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2014
Drugs