Annotation Detail

Information
Associated Genes
NR3C1
Associated Variants
FKBP5 c.106-2636A>G ( ENST00000357266.9, ENST00000536438.5, ENST00000539068.5, ENST00000542713.1 )
FKBP5 c.106-2636A>G ( ENST00000357266.9, ENST00000536438.5, ENST00000539068.5, ENST00000542713.1 )
Associated Disease
post-traumatic stress disorder
Source Database
DisGeNET
Description
As FKBP5 single-nucleotide polymorphism rs1360780 has a putative functional role in the regulation of FKBP5 expression and GR sensitivity, we hypothesized that this polymorphism influences PTSD treatment success.
Pubmed
24959896
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0851573955695258
Year of publication
2014
Drugs