Annotation Detail
Information
- Associated Genes
- NR3C1
- Associated Variants
-
FKBP5 c.106-2636A>G
(
ENST00000357266.9,
ENST00000536438.5,
ENST00000539068.5,
ENST00000542713.1 )
FKBP5 c.106-2636A>G ( ENST00000357266.9, ENST00000536438.5, ENST00000539068.5, ENST00000542713.1 ) - Associated Disease
- Mental Depression
- Source Database
- DisGeNET
- Description
- Polymorphisms in the FK506 binding protein 5 (FKBP5) gene have been shown to influence glucocorticoid receptor sensitivity, stress response regulation, and depression risk in traumatized subjects, with most consistent findings reported for the functional variant rs1360780.
- Pubmed
- 25522420
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0199784160554193
- Year of publication
- 2015
Drugs