Annotation Detail

Information
Associated Genes
CRHR1
Associated Variants
CRHR1 c.33+9204G>A, LINC02210-CRHR1 c.-492-13229G>A ( ENST00000398285.7, ENST00000634540.1, ENST00000580876.6, ENST00000352855.9, ENST00000577353.5, ENST00000314537.10 )
FKBP5 c.106-2636A>G ( ENST00000357266.9, ENST00000536438.5, ENST00000539068.5, ENST00000542713.1 )
CRHR1 c.33+9204G>A, LINC02210-CRHR1 c.-492-13229G>A ( ENST00000314537.10, ENST00000352855.9, ENST00000398285.7, ENST00000577353.5, ENST00000580876.6, ENST00000634540.1 )
FKBP5 c.106-2636A>G ( ENST00000357266.9, ENST00000536438.5, ENST00000539068.5, ENST00000542713.1 )
Associated Disease
child abuse behavior
Source Database
DisGeNET
Description
FKBP5 (rs1360780) and CRHR1 (rs12944712) polymorphisms significantly interacted with child abuse and adult stress to predict increases in physical health ailments over 3 years.
Pubmed
24099078
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Year of publication
2014
Drugs