Annotation Detail
Information
- Associated Genes
- FKBP5
- Associated Variants
-
FKBP5 c.106-2636A>G
(
ENST00000357266.9,
ENST00000536438.5,
ENST00000539068.5,
ENST00000542713.1 )
FKBP5 c.106-2636A>G ( ENST00000357266.9, ENST00000536438.5, ENST00000539068.5, ENST00000542713.1 ) - Associated Disease
- Mental disorders
- Source Database
- DisGeNET
- Description
- The common single nucleotide polymorphism (SNP) rs1360780 (C/T) of the FK506 Binding Protein 5 (FKBP5) gene has been reported to be associated with an altered response of the hypothalamic-pituitary-adrenal (HPA) axis and the development of stress-related psychiatric disorders such as posttraumatic stress disorder (PTSD).
- Pubmed
- 25331639
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00481000882732476
- Year of publication
- 2014
Drugs