chr5:63957874:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr5:63,253,701-63,258,272 |
| hg38 | chr5:63,957,874-63,962,445 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.080 | Catalepsy | NA | RGD | Detail | |
| 0.003 | Dermatitis, Atopic | NA | LHGDN | Detail | |
| <0.001 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree | Detail | |
| 0.080 | Dyskinesia, Drug-Induced | NA | RGD | Detail | |
| 0.006 | Epilepsy, Temporal Lobe | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | Esophageal Neoplasms | NA | GAD | Detail | |
| 0.002 | esophagitis | NA | GAD | Detail | |
| 0.002 | Fatigue | NA | GAD | Detail | |
| 0.002 | chronic fatigue syndrome | NA | GAD | Detail | |
| 0.120 | Fever | NA | CTD_human | Detail | |
| <0.001 | Headache | NA | BeFree | Detail | |
| 0.120 | Learning Disorders | NA | CTD_human | Detail | |
| <0.001 | Lesch-Nyhan syndrome | NA | BeFree | Detail | |
| 0.002 | Low Back Pain | NA | GAD | Detail | |
| <0.001 | Lupus Erythematosus, Systemic | NA | BeFree | Detail | |
| 0.003 | lupus nephritis | NA | BeFree,GAD | Detail | |
| <0.001 | Single major depressive episode | NA | BeFree | Detail | |
| 0.120 | Memory Disorders | NA | CTD_human | Detail | |
| 0.002 | Metaplasia | NA | GAD | Detail | |
| 0.011 | Unipolar Depression | In self-identified white patients with major depressive disorder (N=126) treated... | BeFree | 22727709 | Detail |
| 0.040 | major depressive disorder | In self-identified white patients with major depressive disorder (N=126) treated... | BeFree | 22727709 | Detail |
| <0.001 | nervous system disorder | NA | BeFree | Detail | |
| <0.001 | neuroleptic malignant syndrome | NA | BeFree | Detail | |
| 0.122 | Pain | NA | CTD_human,GAD | Detail | |
| 0.101 | panic disorder | NA | BeFree,GAD,LHGDN,RGD | Detail | |
| 0.083 | Parkinson disease | NA | LHGDN,RGD | Detail | |
| 0.020 | schizophrenia | The authors examined the frequencies of gene polymorphisms in the 5-HT1A (Arg219... | BeFree | 9734554 | Detail |
| 0.003 | Personality Disorders | NA | BeFree,GAD | Detail | |
| <0.001 | Phobia, Social | NA | BeFree | Detail | |
| 0.002 | Premenstrual syndrome | NA | GAD | Detail | |
| 0.120 | Psychoses, Substance-Induced | NA | CTD_human | Detail | |
| <0.001 | Psychotic Disorders | NA | BeFree | Detail | |
| 0.020 | schizophrenia | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | paranoid schizophrenia | NA | BeFree | Detail | |
| 0.002 | Sciatica | NA | GAD | Detail | |
| 0.002 | Scoliosis, unspecified | NA | GAD | Detail | |
| 0.120 | Seizures | NA | CTD_human | Detail | |
| <0.001 | Shared Paranoid Disorder | NA | BeFree | Detail | |
| 0.120 | Stomach Neoplasms | NA | CTD_human | Detail | |
| <0.001 | post-traumatic stress disorder | NA | BeFree | Detail | |
| <0.001 | Substance Use Disorders | NA | BeFree | Detail | |
| 0.007 | Substance Withdrawal Syndrome | NA | GAD | Detail | |
| <0.001 | sudden infant death syndrome | NA | BeFree | Detail | |
| 0.002 | Tobacco use disorder | NA | GAD | Detail | |
| 0.003 | Gilles de la Tourette syndrome | NA | BeFree,GAD | Detail | |
| 0.120 | Tremor | NA | CTD_human | Detail | |
| 0.011 | Unipolar Depression | Interaction of 5-HTT and HTR1A gene polymorphisms in treatment responses to mirt... | BeFree | 24911443 | Detail |
| 0.011 | Unipolar Depression | Multiple lines of research have implicated the serotonin 1A (5-HT1A) receptor in... | BeFree | 25578798 | Detail |
| 0.002 | Weight Gain | NA | GAD | Detail | |
| <0.001 | seasonal affective disorder | NA | BeFree | Detail | |
| <0.001 | Codependency | NA | BeFree | Detail | |
| <0.001 | Emotional Stress | Epigenetic regulation of resistance to emotional stress: possible involvement of... | BeFree | 25048113 | Detail |
| <0.001 | Panic Attacks | NA | BeFree | Detail | |
| 0.003 | Migraine Disorders | NA | BeFree,GAD | Detail | |
| 0.003 | Smith-Lemli-Opitz syndrome | NA | LHGDN | Detail | |
| 0.003 | Depression, Postpartum | NA | LHGDN | Detail | |
| <0.001 | Malaise | NA | BeFree | Detail | |
| <0.001 | Psychiatric symptom | NA | BeFree | Detail | |
| <0.001 | Feeling despair | NA | BeFree | Detail | |
| <0.001 | Sensory Discomfort | NA | BeFree | Detail | |
| 0.120 | Cocaine-Related Disorders | NA | CTD_human | Detail | |
| <0.001 | Panic disorder with agoraphobia | NA | BeFree | Detail | |
| 0.052 | Mental Depression | Six functional SNPs in genes related to the serotonergic system were examined: s... | BeFree | 20515362 | Detail |
| 0.011 | depressive disorder | Six functional SNPs in genes related to the serotonergic system were examined: s... | BeFree | 20515362 | Detail |
| 0.005 | age related macular degeneration | NA | GAD | Detail | |
| <0.001 | Anxiety and fear | NA | BeFree | Detail | |
| 0.120 | Bradycardia | NA | CTD_human | Detail | |
| 0.003 | dementia | NA | LHGDN | Detail | |
| 0.003 | Hepatitis C, Chronic | NA | BeFree,LHGDN | Detail | |
| 0.002 | Malignant neoplasm of esophagus | NA | GAD | Detail | |
| 0.040 | major depressive disorder | Several studies have linked 5-HT1A C1019G and BDNF G196A (Val66Met) gene polymor... | BeFree | 17401528 | Detail |
| 0.011 | Unipolar Depression | Several studies have linked 5-HT1A C1019G and BDNF G196A (Val66Met) gene polymor... | BeFree | 17401528 | Detail |
| 0.020 | schizophrenia | While further research into the molecular mechanisms underlying this interaction... | BeFree | 19352591 | Detail |
| 0.003 | Gilles de la Tourette syndrome | As neuroimaging studies allude to dopaminergic and serotonergic dysfunction in G... | BeFree | 20010450 | Detail |
| <0.001 | Obsessive compulsive behavior | NA | BeFree | Detail | |
| <0.001 | depression anxiety disorder | NA | BeFree | Detail | |
| <0.001 | Completed Suicide | NA | BeFree | Detail | |
| <0.001 | Adult attention deficit hyperactivity disorder | NA | BeFree | Detail | |
| <0.001 | social stress | Expression of the 5-HT1A serotonin receptor in the hippocampus is required for s... | BeFree | 25288485 | Detail |
| 0.006 | attention deficit hyperactivity disorder | NA | BeFree,GAD | Detail | |
| 0.040 | major depressive disorder | Interaction of 5-HTT and HTR1A gene polymorphisms in treatment responses to mirt... | BeFree,GAD,LHGDN | 24911443 | Detail |
| 0.040 | major depressive disorder | Multiple lines of research have implicated the serotonin 1A (5-HT1A) receptor in... | BeFree,GAD,LHGDN | 25578798 | Detail |
| 0.002 | Depression and Suicide | NA | BeFree | Detail | |
| <0.001 | NEUROTICISM | NA | BeFree | Detail | |
| 0.003 | PANIC DISORDER 1 | NA | BeFree | Detail | |
| <0.001 | Depressive Disorder, Treatment-Resistant | NA | BeFree | Detail | |
| 0.002 | Weight Gain Adverse Event | NA | GAD | Detail | |
| 0.002 | Acute Disease | NA | GAD | Detail | |
| 0.002 | adenocarcinoma | NA | GAD | Detail | |
| <0.001 | Affective Symptoms | NA | BeFree | Detail | |
| <0.001 | agoraphobia | NA | BeFree | Detail | |
| 0.011 | Alcoholic Intoxication, Chronic | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | Alzheimer's disease | NA | LHGDN | Detail | |
| 0.080 | Anxiety | NA | MGD | Detail | |
| 0.008 | Anxiety Disorders | Our results, therefore, translate evidence from animal studies to humans and sug... | BeFree | 25514753 | Detail |
| 0.120 | Apnea | NA | CTD_human | Detail | |
| 0.007 | As If Personality | NA | GAD | Detail | |
| 0.002 | autistic disorder | NA | GAD | Detail | |
| 0.003 | Mental disorders | NA | BeFree | Detail | |
| 0.008 | bipolar disorder | NA | BeFree,GAD | Detail | |
| <0.001 | Depression, Bipolar | NA | BeFree | Detail | |
| <0.001 | borderline personality disorder | NA | BeFree | Detail | |
| <0.001 | Bulimia | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In self-identified white patients with major depressive disorder (N=126) treated with open-label dul... | DisGeNET | Detail |
| In self-identified white patients with major depressive disorder (N=126) treated with open-label dul... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The authors examined the frequencies of gene polymorphisms in the 5-HT1A (Arg219Leu) and 5-HT2A (Thr... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Interaction of 5-HTT and HTR1A gene polymorphisms in treatment responses to mirtazapine in patients ... | DisGeNET | Detail |
| Multiple lines of research have implicated the serotonin 1A (5-HT1A) receptor in major depressive di... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Epigenetic regulation of resistance to emotional stress: possible involvement of 5-HT1A receptor-med... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Six functional SNPs in genes related to the serotonergic system were examined: serotonin transporter... | DisGeNET | Detail |
| Six functional SNPs in genes related to the serotonergic system were examined: serotonin transporter... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Several studies have linked 5-HT1A C1019G and BDNF G196A (Val66Met) gene polymorphisms to major depr... | DisGeNET | Detail |
| Several studies have linked 5-HT1A C1019G and BDNF G196A (Val66Met) gene polymorphisms to major depr... | DisGeNET | Detail |
| While further research into the molecular mechanisms underlying this interaction is needed, our resu... | DisGeNET | Detail |
| As neuroimaging studies allude to dopaminergic and serotonergic dysfunction in GTS and serotonin as ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilie... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Interaction of 5-HTT and HTR1A gene polymorphisms in treatment responses to mirtazapine in patients ... | DisGeNET | Detail |
| Multiple lines of research have implicated the serotonin 1A (5-HT1A) receptor in major depressive di... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our results, therefore, translate evidence from animal studies to humans and suggest a central role ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386599040 dbSNP
- Genome
- hg38
- Position
- chr5:63,957,874-63,962,445
- Variant Type
- snv
Genome browser