Annotation Detail
Information
- Associated Genes
- HTR1A
- Associated Variants
-
HTR1A MUTATION
HTR1A MUTATION
HTR2A p.Thr25Ser (p.T25S) ( ENST00000543956.5, ENST00000542664.4 )
HTR2A p.Thr25Asn (p.T25N) ( ENST00000543956.5, ENST00000542664.4 )
HTR1A p.Arg220Leu (p.R220L) ( ENST00000323865.5 )
HTR2A p.Thr25Ser (p.T25S) ( ENST00000542664.4, ENST00000543956.5 )
HTR2A p.Thr25Asn (p.T25N) ( ENST00000542664.4, ENST00000543956.5 )
HTR1A p.Arg220Leu (p.R220L) ( ENST00000323865.5 ) - Associated Disease
- schizophrenia
- Source Database
- DisGeNET
- Description
- The authors examined the frequencies of gene polymorphisms in the 5-HT1A (Arg219Leu) and 5-HT2A (Thr25Asn and His452Tyr) receptor genes in 29 patients previously diagnosed with neuroleptic malignant syndrome, 94 neuroleptic-treated patients with schizophrenia who had no history of neuroleptic malignant syndrome, and 94 healthy comparison subjects.
- Pubmed
- 9734554
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0204315422327334
- Year of publication
- 1998
Drugs