Sciatica

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Information
Disease name
Sciatica
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03879447 Active, not recruiting Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis June 24, 2019 December 2027
NCT00011804 Completed Phase 2 Topiramate in the Treatment of Sciatica February 2001 February 2005
NCT00018200 Completed Phase 2 Effect of Antidepressants on Back Pain April 1999 March 2004
NCT00044109 Completed Phase 2 Magnets in the Treatment of Sciatica August 2002 June 2006
NCT00991172 Completed Phase 2 A Study to Evaluate the Safety and Efficacy of Subcutaneously Administered REGN475(SAR164877) in Patients With Sciatic Pain November 2009 May 2010
NCT01989403 Completed Alternative and Integrative Therapy for Lumbar Disk Herniation February 2006 March 2013
NCT02130271 Completed PET/MRI Imaging of Neuraxial Inflammation in Sciatica Patients April 2014 December 2018
NCT02284542 Completed NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators November 1, 2014 January 31, 2017
NCT02384928 Completed N/A Effects of Shinbaro Pharmacopuncture in Sciatic Pain Patients With Lumbar Disc Herniation September 9, 2015 March 16, 2017
NCT02391350 Completed N/A Management Strategies for Patients With Low Back Pain and Sciatica February 2015 October 2019
NCT02618278 Completed Phase 3 Physiotherapy for Sciatica; Is Earlier Better? February 2016 November 2016
NCT02644421 Completed Phase 1 Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica) November 2015 July 2017
NCT02753101 Completed Early Phase 1 [18F]FTC-146 PET/MRI in Healthy Volunteers and in CRPS and Sciatica February 9, 2016 February 16, 2017
NCT02889484 Completed Outcome of Surgery for Sciatica - a Comparison of Data From Three National Quality Registries January 2011 June 2015
NCT03347929 Completed Phase 4 NSAIDs in Sciatica NSAIDS IN SCIATICA November 30, 2017 June 22, 2023
NCT03426215 Completed Long-Term Course of Korean Medicine Treatment for Lumbar Disc Herniation March 10, 2018 April 28, 2018
NCT03571503 Completed The Effectiveness of Doin (Conduction Exercise) of the Pelvic Joint for HLD With Radiating Leg Pain July 9, 2018 September 20, 2019
NCT03750591 Completed Observational Study on Effectiveness and Safety of Integrative Korean Medicine Treatment for Inpatients With Sciatica Due to Lumbar Intervertebral Disc Herniation March 31, 2018 November 8, 2019
NCT04145310 Completed Phase 1/Phase 2 BOL-DP-o-04 in Patients With Low Back Pain and Sciatica November 27, 2018 July 7, 2022
NCT04155450 Completed N/A Effects of Extension Biased External Limb Loading in Addition to McKenzie Extension Protocol in Lumbar Derangement Syndrome November 1, 2019 May 1, 2020
NCT04209322 Completed N/A Trial of Pulsed Radiofrequency for Sciatica and Disc Herniation February 1, 2017 January 31, 2020
NCT04326699 Completed N/A Bilateral Sacroiliac Joint (SIJ) Injection in Lumbar Disc Prolapse March 15, 2020 October 15, 2020
NCT04695912 Completed N/A The Effect of Accelerometer Guided App Feedback on Change in Activity in Patients With Low Back April 26, 2019 June 20, 2019
NCT04918238 Completed N/A Effect of Muscle Energy Techniques on Functional Abilities in Patients With Discogenic Unilateral Sciatica February 1, 2021 June 1, 2021
NCT05000658 Completed Phase 3 Efficacy of Soluble Dexamethasone in Refractory Sciatica December 16, 2021 March 15, 2023
NCT05022121 Completed N/A Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain January 26, 2022 February 20, 2023
NCT05626140 Completed Phase 3 COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA September 28, 2021 July 31, 2022
NCT05959317 Completed N/A Effects of Pilates Exercises and Neural Dynamic Mobilization in Sciatica Patients March 5, 2023 July 30, 2023
NCT06275750 Completed N/A Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain August 21, 2023 January 11, 2024
NCT00246948 Completed N/A The Efficacy of Active Conservative Treatment for Patients With Severe Sciatica. A Randomized Clinical Controlled Trial November 2001 August 2003
NCT00317447 Completed Phase 3 The Efficacy of Oral Steroids in the Treatment of Acute Sciatica February 2002 April 2004
NCT00364546 Completed Phase 3 A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain July 2006 July 2007
NCT00364572 Completed Phase 1/Phase 2 Efficacy of Epidural Etanercept in the Treatment of Sciatica May 2006 December 2007
NCT00415220 Completed Phase 2 Manipulation or Microdiscectomy For Sciatica? A Prospective Randomized Controlled Trial. January 2000 May 2004
NCT00470509 Completed Phase 2 Adalimumab in Severe and Acute Sciatica May 2005 June 2008
NCT00668434 Completed Phase 2 Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica November 2008 September 2013
NCT00749996 Completed Phase 4 Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease November 2006 June 2013
NCT00942227 Completed Phase 3 The Value of Traction in Treatment of Lumbar Radiculopathy July 2009 December 2012
NCT00961766 Completed Phase 1 Evaluate the Safety, Tolerability and Pharmacokinetics of BG00010 (Neublastin) Administered to Sciatica Participants August 2009 February 2012
NCT00009672 Completed Phase 2 Pain Treatment for Sciatica January 30, 2001 December 12, 2006
NCT01145105 Completed N/A Neural Dynamics Technique for the Treatment of Chronic Radicular Low Back Pain June 2010 July 2011
NCT01240876 Completed Phase 1/Phase 2 Study to Evaluate the Safety and Efficacy of Placulumab (CEP-37247) Administered by the Transforaminal Epidural Route for the Treatment of Patients With Lumbosacral Radicular Pain Associated With Disk Herniation January 2011 April 2013
NCT01405833 Completed Phase 1 Study of the Safety, Tolerability, Pharmacokinetics and Safety of BG00010 (Neublastin) in Subjects With Sciatica. July 2011 September 2012
NCT01495923 Completed N/A Steroids Versus Gabapentin December 2011 September 2014
NCT01816334 Completed Phase 4 Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica January 2013 January 2016
NCT01832844 Completed N/A Effects of Control Scan for Presumed Difficult Epidural Infiltrations (ECHORACHIS) April 2013 January 2014
NCT01873404 Completed Phase 2 BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy June 2013 March 2015
NCT01917825 Completed Phase 2 A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy July 2013 October 2016
NCT01934868 Completed Phase 4 Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg December 1, 2013 April 10, 2023
NCT01954199 Completed N/A The Effectiveness of Neurodynamic Techniques in Patients With Nerve-Related Leg Pain March 2015 April 2016
NCT05907356 Not yet recruiting N/A Effect of Sciatic Nerve Slider Technique in Different Positions in Low Back Pain Patients July 2023 May 2024
NCT03924791 Recruiting N/A Transforaminal Epidural Injection in Acute Sciatica June 1, 2019 July 2026
NCT06179901 Recruiting N/A The Effect of Early MSAT Treatment on Sciatica Caused by Traffic Accidents October 30, 2023 December 31, 2024
NCT03801512 Recruiting N/A Comparing the Efficacy of Steroid, Acupuncture and Platelet Rich Plasma Injection in Patients With Sciatica April 24, 2019 May 28, 2024
NCT03377088 Suspended N/A Aromatherapy Randomization of Pain Management in Adults December 11, 2017 February 28, 2024
NCT00269503 Terminated N/A Chiropractic Prone Distraction for Lower Back Pain March 2006 June 2006
NCT02951377 Terminated Phase 1 Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy October 1, 2017 January 31, 2020
NCT02512081 Unknown status "The Lived Experience of Investigations for Sciatica" September 2015 October 2016
NCT03880370 Unknown status RELATIONSHIP OF LUMBOPELVIC MUSCULATURE WITH FUNCTIONAL TESTS IN NON-PROFESSIONAL ATHLETES WITH LUMBAR DISC HERNIATION April 1, 2019 December 31, 2019
NCT03887962 Unknown status N/A Virtual Environment Rehabilitation for Patients With Motor Neglect Trial May 1, 2017 November 1, 2021
NCT02770963 Unknown status N/A Efficacy of Acupuncture for Discogenic Sciatica May 2016 June 2018
NCT02777320 Unknown status Phase 4 Comparison of Intravenous Ibuprofen and Paracetamol in Patients With Sciatica Presented to the Emergency Department March 2016 September 2016
NCT01749839 Unknown status Pain Relief by Platelet-rich Plasma (PRP) Treatment December 2012 December 2014
NCT05195593 Unknown status Spine Registration Using 3D Scanning - Arise January 5, 2022 October 2022
NCT03453775 Unknown status N/A Ultrasound-guided Lumbar Periradicular Injection: a Non Irradiating Infiltration Technique February 27, 2018 May 30, 2018
NCT03598153 Unknown status A Registry Study of Shujinjianyao Pill Used in Clinical Real World July 25, 2018 December 31, 2019
NCT04660656 Unknown status Predictive Value of the Five-repetition Sit-to-stand Test After Lumbar Spine surgerySTS-3 Study. November 25, 2020 May 1, 2022
NCT00573807 Unknown status Phase 1 Energy Specific Far Infrared Radiation Treatment for Sciatica January 2006 December 2008
NCT00107055 Unknown status Phase 2 Study of REN-1654 in Patients With Sciatica Pain December 2003 April 2005
NCT02504996 Unknown status Phase 4 IV Paracetamol vs IV Morphine vs Placebo in Sciatalgia January 2015 March 2016
NCT04764890 Unknown status N/A Effectiveness of Electro-acupuncture and Manual Therapy on Pain and Fucntion in Patients With Sciatica February 11, 2021 June 2021
NCT00163553 Unknown status Phase 3 Neuraxial Pethidine After Lumbar Surgery Trial December 2004
NCT02897336 Withdrawn N/A Ultrasound-guided Caudal or Interlaminar Corticosteroid Epidural Injection for Sciatica July 2016 December 2017
NCT02313350 Withdrawn N/A Intradiscal Discogel® in Resistant Sciatica September 2017 January 2018
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0011868
ICD10 preferred id (Insert disease from ICD10)
D0010582
ICD10 class code (Insert disease from ICD10)
M54.3
MeSH unique ID (MeSH (Medical Subject Headings))
D012585