chr20:53421199:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr20:52,037,738-52,038,195 |
| hg38 | chr20:53,421,199-53,421,656 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | squamous cell carcinoma | NA | BeFree | Detail | |
| <0.001 | Cardiomyopathy, Dilated | NA | BeFree | Detail | |
| 0.003 | Cardiovascular Diseases | NA | BeFree | Detail | |
| <0.001 | Transient ischemic attack | NA | BeFree | Detail | |
| <0.001 | ulcerative colitis | CRP and CRP genotype differ between pediatric patients with CD and UC with a hig... | BeFree | 25636121 | Detail |
| 0.001 | colorectal carcinoma | NA | BeFree | Detail | |
| 0.003 | Coronary Arteriosclerosis | Renin-angiotensin system genetic polymorphisms: lack of association with CRP lev... | BeFree | 23392788 | Detail |
| 0.003 | Coronary Arteriosclerosis | A novel haplotype within C-reactive protein gene influences CRP levels and coron... | BeFree | 24965144 | Detail |
| 0.005 | Coronary heart disease | Renin-angiotensin system genetic polymorphisms: lack of association with CRP lev... | BeFree | 23392788 | Detail |
| 0.005 | Coronary heart disease | A novel haplotype within C-reactive protein gene influences CRP levels and coron... | BeFree | 24965144 | Detail |
| 0.005 | Coronary heart disease | The plasma ccf-mtDNA levels and CRP were significantly elevated in DM compared w... | BeFree | 26299063 | Detail |
| 0.001 | Crohn Disease | CRP and CRP genotype differ between pediatric patients with CD and UC with a hig... | BeFree | 25636121 | Detail |
| 0.003 | Diabetes | The plasma ccf-mtDNA levels and CRP were significantly elevated in DM compared w... | BeFree | 26299063 | Detail |
| 0.003 | diabetes mellitus | The plasma ccf-mtDNA levels and CRP were significantly elevated in DM compared w... | BeFree | 26299063 | Detail |
| <0.001 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree | Detail | |
| <0.001 | encephalitis | Furthermore, G carriers (GG + GC) (10.6 ±.29 mg/l) had significantly higher bloo... | BeFree | 25081498 | Detail |
| <0.001 | Fatigue | NA | BeFree | Detail | |
| <0.001 | chronic granulomatous disease | NA | BeFree | Detail | |
| <0.001 | Hepatolenticular Degeneration | NA | BeFree | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| <0.001 | Hypercholesterolemia, Familial | OLS (ordinary least squares) regression analysis revealed that miR-33a was signi... | BeFree | 26229086 | Detail |
| 0.002 | Hypertensive disease | NA | BeFree | Detail | |
| <0.001 | Inflammatory Bowel Diseases | Serum C-reactive protein and CRP genotype in pediatric inflammatory bowel diseas... | BeFree | 25636121 | Detail |
| <0.001 | influenza | NA | BeFree | Detail | |
| <0.001 | ischemia | NA | BeFree | Detail | |
| <0.001 | Kidney Diseases | NA | BeFree | Detail | |
| <0.001 | Kidney Failure, Acute | NA | BeFree | Detail | |
| <0.001 | leukopenia | NA | BeFree | Detail | |
| <0.001 | Liver neoplasms | NA | BeFree | Detail | |
| <0.001 | Chronic Obstructive Airway Disease | NA | BeFree | Detail | |
| 0.001 | Lupus Erythematosus, Systemic | NA | BeFree | Detail | |
| <0.001 | lupus nephritis | NA | BeFree | Detail | |
| <0.001 | melanoma | CRP measurement should be considered for incorporation into prospective studies ... | BeFree | 25779565 | Detail |
| <0.001 | Mucocutaneous Lymph Node Syndrome | Common variants in the CRP promoter are associated with a high C-reactive protei... | BeFree | 25266886 | Detail |
| <0.001 | neutropenia | NA | BeFree | Detail | |
| 0.003 | obesity | Further, PPARs polymorphisms interact with overweight/obesity to set CRP levels. | BeFree | 24599720 | Detail |
| 0.003 | obesity | Association of IL-6 and CRP gene polymorphisms with obesity and metabolic disord... | BeFree | 25993353 | Detail |
| <0.001 | osteomyelitis | NA | BeFree | Detail | |
| <0.001 | osteosarcoma | NA | BeFree | Detail | |
| <0.001 | Pneumococcal Infections | NA | BeFree | Detail | |
| <0.001 | pneumonia | NA | BeFree | Detail | |
| <0.001 | Mycoplasma pneumonia | NA | BeFree | Detail | |
| <0.001 | psoriasis | The history of psoriasis was associated with greater age [OR 1.05 (95% CI 1.00, ... | BeFree | 25234663 | Detail |
| <0.001 | psoriasis | US abnormalities were independent of ePsA clinical indices (except erosions - ev... | BeFree | 25797649 | Detail |
| <0.001 | pulmonary embolism | NA | BeFree | Detail | |
| <0.001 | Septicemia | NA | BeFree | Detail | |
| <0.001 | ankylosing spondylitis | C-reactive protein polymorphisms influence serum CRP-levels independent of disea... | BeFree | 25603416 | Detail |
| <0.001 | ankylosing spondylitis | We describe three mother-daughter couples concordant for AS and HLA-B27, both tr... | BeFree | 25962691 | Detail |
| <0.001 | post-traumatic stress disorder | Association of CRP genetic variation and CRP level with elevated PTSD symptoms a... | BeFree | 25827033 | Detail |
| 0.002 | Cerebrovascular accident | CRP gene (1059G>C) polymorphism and its plasma levels in ischemic stroke and hem... | BeFree | 24771073 | Detail |
| <0.001 | Thromboembolism | NA | BeFree | Detail | |
| <0.001 | trachoma | NA | BeFree | Detail | |
| <0.001 | tuberculosis | NA | BeFree | Detail | |
| <0.001 | urinary tract infection | NA | BeFree | Detail | |
| <0.001 | Neurofibrillary degeneration (morphologic abnormality) | NA | BeFree | Detail | |
| <0.001 | essential hypertension | NA | BeFree | Detail | |
| <0.001 | Depressive Symptoms | NA | BeFree | Detail | |
| <0.001 | Vascular inflammations | Moreover, a remarkable association of the G82S variant with serum CRP levels imp... | BeFree | 20668462 | Detail |
| <0.001 | Deep Vein Thrombosis | NA | BeFree | Detail | |
| <0.001 | Myocardial Ischemia | NA | BeFree | Detail | |
| <0.001 | Deep thrombophlebitis | NA | BeFree | Detail | |
| <0.001 | Joint swelling | NA | BeFree | Detail | |
| 0.001 | acute myocardial infarction | NA | BeFree | Detail | |
| <0.001 | Disease of capillaries | NA | BeFree | Detail | |
| <0.001 | Malnutrition | NA | BeFree | Detail | |
| <0.001 | hepatocellular adenoma | NA | BeFree | Detail | |
| <0.001 | cholangiocarcinoma | NA | BeFree | Detail | |
| <0.001 | Reactive systemic amyloidosis | NA | BeFree | Detail | |
| <0.001 | Morning stiffness (>1 hour) | NA | BeFree | Detail | |
| <0.001 | pelvic inflammatory disease | We sought to determine whether sCD40L was an efficient serum marker as with WBC ... | BeFree | 25192781 | Detail |
| <0.001 | Dyslipidemias | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of lung | NA | BeFree | Detail | |
| <0.001 | age related macular degeneration | NA | BeFree | Detail | |
| <0.001 | Sepsis | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of esophagus | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma Of Esophagus | NA | BeFree | Detail | |
| <0.001 | Obesity, Abdominal | NA | BeFree | Detail | |
| <0.001 | Superficial ulcer | US abnormalities were independent of ePsA clinical indices (except erosions - ev... | BeFree | 25797649 | Detail |
| <0.001 | Senile Plaques | NA | BeFree | Detail | |
| <0.001 | Maturity onset diabetes mellitus in young | NA | BeFree | Detail | |
| <0.001 | Cholesteryl Ester Transfer Protein Deficiency | NA | BeFree | Detail | |
| <0.001 | Chorea Acanthocytosis Syndrome | NA | BeFree | Detail | |
| <0.001 | Chronic Kidney Insufficiency | NA | BeFree | Detail | |
| <0.001 | Chronic rejection of renal transplant | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of liver | NA | BeFree | Detail | |
| <0.001 | Overweight | Further, PPARs polymorphisms interact with overweight/obesity to set CRP levels. | BeFree | 24599720 | Detail |
| 0.001 | Metabolic syndrome X | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of esophagus | NA | BeFree | Detail | |
| <0.001 | Osteosarcoma of bone | NA | BeFree | Detail | |
| <0.001 | Carcinogenesis | NA | BeFree | Detail | |
| <0.001 | breast carcinoma | Associations between ALOX, COX, and CRP polymorphisms and breast cancer among Hi... | BeFree | 25339205 | Detail |
| <0.001 | Carcinoma of lung | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of gastrointestinal tract | For gastrointestinal cancer, a doubling in YKL-40 was associated with a multifac... | BeFree | 26095694 | Detail |
| <0.001 | Secondary malignant neoplasm of lymph node | NA | BeFree | Detail | |
| <0.001 | Community acquired pneumonia | We used clinical indicators (fever, time for defeverscence, heart and breath rat... | BeFree | 25315615 | Detail |
| <0.001 | Acute anterior uveitis | Newly developed AAU was associated with an elevated time-varying CRP [HR 1.02 (9... | BeFree | 25234663 | Detail |
| <0.001 | Dissecting aneurysm of the thoracic aorta | NA | BeFree | Detail | |
| <0.001 | metabolic disturbance | Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliora... | BeFree | 25010431 | Detail |
| <0.001 | Periodontal infection | NA | BeFree | Detail | |
| <0.001 | Malignant Squamous Cell Neoplasm | NA | BeFree | Detail | |
| <0.001 | Acute Cerebrovascular Accidents | NA | BeFree | Detail | |
| <0.001 | Invasive breast carcinoma | NA | BeFree | Detail | |
| <0.001 | transient cerebral ischemia | NA | BeFree | Detail | |
| <0.001 | Vascular inflammations | NA | BeFree | Detail | |
| 0.001 | Ischemic stroke | CRP gene (1059G>C) polymorphism and its plasma levels in ischemic stroke and hem... | BeFree | 24771073 | Detail |
| <0.001 | Acute coronary syndrome | NA | BeFree | Detail | |
| <0.001 | Vascular occlusion | NA | BeFree | Detail | |
| <0.001 | Pneumococcal bacteraemia | NA | BeFree | Detail | |
| <0.001 | TNF receptor-associated periodic fever syndrome (TRAPS) | NA | BeFree | Detail | |
| <0.001 | Inflammatory disorder | NA | BeFree | Detail | |
| <0.001 | Cardiovascular morbidity | NA | BeFree | Detail | |
| <0.001 | pancreatic ductal adenocarcinoma | Furthermore, we found that the levels of TNFSF13 in PDAC lesions and TNFSF13 and... | BeFree | 25636208 | Detail |
| 0.001 | colorectal cancer | NA | BeFree | Detail | |
| <0.001 | Chronic Kidney Diseases | NA | BeFree | Detail | |
| <0.001 | Renal tubular necrosis | NA | BeFree | Detail | |
| <0.001 | liver carcinoma | NA | BeFree | Detail | |
| 0.001 | Ischemic Cerebrovascular Accident | CRP gene (1059G>C) polymorphism and its plasma levels in ischemic stroke and hem... | BeFree | 24771073 | Detail |
| <0.001 | Mannose-Binding Protein Deficiency | NA | BeFree | Detail | |
| <0.001 | AA amyloidosis | NA | BeFree | Detail | |
| <0.001 | Metabolic disorders in children | Association of IL-6 and CRP gene polymorphisms with obesity and metabolic disord... | BeFree | 25993353 | Detail |
| 0.002 | arteriosclerosis | NA | BeFree | Detail | |
| <0.001 | arthritis | NA | BeFree | Detail | |
| <0.001 | Arthritis, Psoriatic | We have shown that CRP gene polymorphisms are higher in control subjects than Ps... | BeFree | 24696367 | Detail |
| <0.001 | asthma | NA | BeFree | Detail | |
| 0.002 | atherosclerosis | NA | BeFree | Detail | |
| <0.001 | Bacteremia | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of breast | Associations between ALOX, COX, and CRP polymorphisms and breast cancer among Hi... | BeFree | 25339205 | Detail |
| <0.001 | Cachexia | NA | BeFree | Detail | |
| <0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| CRP and CRP genotype differ between pediatric patients with CD and UC with a high inflammatory burde... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Renin-angiotensin system genetic polymorphisms: lack of association with CRP levels in patients with... | DisGeNET | Detail |
| A novel haplotype within C-reactive protein gene influences CRP levels and coronary heart disease ri... | DisGeNET | Detail |
| Renin-angiotensin system genetic polymorphisms: lack of association with CRP levels in patients with... | DisGeNET | Detail |
| A novel haplotype within C-reactive protein gene influences CRP levels and coronary heart disease ri... | DisGeNET | Detail |
| The plasma ccf-mtDNA levels and CRP were significantly elevated in DM compared with healthy controls... | DisGeNET | Detail |
| CRP and CRP genotype differ between pediatric patients with CD and UC with a high inflammatory burde... | DisGeNET | Detail |
| The plasma ccf-mtDNA levels and CRP were significantly elevated in DM compared with healthy controls... | DisGeNET | Detail |
| The plasma ccf-mtDNA levels and CRP were significantly elevated in DM compared with healthy controls... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Furthermore, G carriers (GG + GC) (10.6 ±.29 mg/l) had significantly higher blood CRP levels compare... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| OLS (ordinary least squares) regression analysis revealed that miR-33a was significantly affected by... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Serum C-reactive protein and CRP genotype in pediatric inflammatory bowel disease: influence on phen... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| CRP measurement should be considered for incorporation into prospective studies of outcome in patien... | DisGeNET | Detail |
| Common variants in the CRP promoter are associated with a high C-reactive protein level in Kawasaki ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Further, PPARs polymorphisms interact with overweight/obesity to set CRP levels. | DisGeNET | Detail |
| Association of IL-6 and CRP gene polymorphisms with obesity and metabolic disorders in children and ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The history of psoriasis was associated with greater age [OR 1.05 (95% CI 1.00, 1.11)] and lower CRP... | DisGeNET | Detail |
| US abnormalities were independent of ePsA clinical indices (except erosions - even if represented on... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| C-reactive protein polymorphisms influence serum CRP-levels independent of disease activity in ankyl... | DisGeNET | Detail |
| We describe three mother-daughter couples concordant for AS and HLA-B27, both treated with TNF-α inh... | DisGeNET | Detail |
| Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological res... | DisGeNET | Detail |
| CRP gene (1059G>C) polymorphism and its plasma levels in ischemic stroke and hemorrhagic stroke in a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Moreover, a remarkable association of the G82S variant with serum CRP levels implied that the preval... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We sought to determine whether sCD40L was an efficient serum marker as with WBC and CRP in PID patie... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| US abnormalities were independent of ePsA clinical indices (except erosions - even if represented on... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Further, PPARs polymorphisms interact with overweight/obesity to set CRP levels. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Associations between ALOX, COX, and CRP polymorphisms and breast cancer among Hispanic and non-Hispa... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| For gastrointestinal cancer, a doubling in YKL-40 was associated with a multifactorially and CRP adj... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We used clinical indicators (fever, time for defeverscence, heart and breath rate, saturation, and l... | DisGeNET | Detail |
| Newly developed AAU was associated with an elevated time-varying CRP [HR 1.02 (95% CI 1.01, 1.04)]. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturb... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| CRP gene (1059G>C) polymorphism and its plasma levels in ischemic stroke and hemorrhagic stroke in a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Furthermore, we found that the levels of TNFSF13 in PDAC lesions and TNFSF13 and CRP in serum were s... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| CRP gene (1059G>C) polymorphism and its plasma levels in ischemic stroke and hemorrhagic stroke in a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Association of IL-6 and CRP gene polymorphisms with obesity and metabolic disorders in children and ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We have shown that CRP gene polymorphisms are higher in control subjects than PsA patients, and TLR ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Associations between ALOX, COX, and CRP polymorphisms and breast cancer among Hispanic and non-Hispa... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386556293 dbSNP
- Genome
- hg38
- Position
- chr20:53,421,199-53,421,656
- Variant Type
- snv
Genome browser