chr3:66429221:> Detail (hg19)

Information

Genome

Assembly Position
hg19 chr3:66,429,221-66,551,446
hg38 chr3:66,378,797-66,501,022 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.003 renal cell carcinoma NA BeFree,LHGDN Detail
<0.001 squamous cell carcinoma NA BeFree Detail
<0.001 colorectal carcinoma LRIG1, a 3p tumor suppressor, represses EGFR signaling and is a novel epigenetic... BeFree 26159916 Detail
<0.001 Colorectal Neoplasms NA BeFree Detail
<0.001 glioblastoma NA BeFree Detail
0.003 Glioma LRIG1 enhances chemosensitivity by modulating BCL-2 expression and receptor tyro... BeFree 25048475 Detail
0.003 Glioma The soluble LRIG1 ectodomain is demonstrated to be shed naturally and inhibit th... BeFree 25353163 Detail
0.003 Glioma MiR-20a mediated TMZ-resistance in glioblastoma cells through negatively regulat... BeFree 25960225 Detail
0.003 Glioma In the single-locus analysis, six single-nucleotide polymorphisms [ERCC1 3' untr... BeFree 19124499 Detail
<0.001 chronic lymphocytic leukemia NA BeFree Detail
<0.001 Neoplasm Metastasis NA BeFree Detail
<0.001 oligodendroglioma In oligodendroglioma, LRIG2 expression is associated with poor survival, suggest... BeFree 25353163 Detail
<0.001 ovarian carcinoma NA BeFree Detail
<0.001 Skin Neoplasms Interestingly, the adnexal SC marker Lrig1 was upregulated in SCLTs, showing tha... BeFree 25659584 Detail
0.002 Tobacco use disorder NA GAD Detail
0.001 Malignant neoplasm of lung NA BeFree Detail
<0.001 Epithelial hyperplasia of skin NA BeFree Detail
<0.001 Cancer of Head and Neck NA BeFree Detail
<0.001 Solid tumour NA BeFree Detail
<0.001 anaplastic oligodendroglioma In oligodendroglioma, LRIG2 expression is associated with poor survival, suggest... BeFree 25353163 Detail
<0.001 Malignant neoplasm of prostate NA BeFree Detail
<0.001 endometrial carcinoma NA BeFree Detail
<0.001 Malignant glioma NA BeFree Detail
0.001 Carcinogenesis NA BeFree Detail
<0.001 prostate carcinoma NA BeFree Detail
0.001 breast carcinoma NA BeFree Detail
0.001 Carcinoma of lung NA BeFree Detail
<0.001 Carcinoma of bladder Adenovirus-mediated LRIG1 expression enhances the chemosensitivity of bladder ca... BeFree 25695283 Detail
<0.001 Well Differentiated Oligodendroglioma In oligodendroglioma, LRIG2 expression is associated with poor survival, suggest... BeFree 25353163 Detail
<0.001 Rhabdoid Tumor of the Kidney These results demonstrated that LRIG1 can improve chemosensitivity by modulating... BeFree 25048475 Detail
<0.001 Malignant neoplasm of ovary NA BeFree Detail
0.006 Mammary Neoplasms NA BeFree,LHGDN Detail
<0.001 colorectal cancer LRIG1, a 3p tumor suppressor, represses EGFR signaling and is a novel epigenetic... BeFree 26159916 Detail
<0.001 Glioblastoma multiforme Here, we aimed to elucidate the relationship between miR-20a, its predicted targ... BeFree 25960225 Detail
<0.001 Non-Neoplastic Disorder NA BeFree Detail
<0.001 uterine corpus cancer NA BeFree Detail
<0.001 Nasopharyngeal carcinoma In early stage breast cancer, LRIG1 copy number was recently shown to predict ea... BeFree 25180912 Detail
<0.001 adenoma NA BeFree Detail
<0.001 Astrocytoma NA BeFree Detail
<0.001 Malignant neoplasm of urinary bladder Adenovirus-mediated LRIG1 expression enhances the chemosensitivity of bladder ca... BeFree 25695283 Detail
0.001 Malignant neoplasm of breast NA BeFree Detail
<0.001 Malignant neoplasm of endometrium NA BeFree Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
NA DisGeNET Detail
LRIG1, a 3p tumor suppressor, represses EGFR signaling and is a novel epigenetic silenced gene in co... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
LRIG1 enhances chemosensitivity by modulating BCL-2 expression and receptor tyrosine kinase signalin... DisGeNET Detail
The soluble LRIG1 ectodomain is demonstrated to be shed naturally and inhibit the progression of gli... DisGeNET Detail
MiR-20a mediated TMZ-resistance in glioblastoma cells through negatively regulating LRIG1 expression... DisGeNET Detail
In the single-locus analysis, six single-nucleotide polymorphisms [ERCC1 3' untranslated region (UTR... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In oligodendroglioma, LRIG2 expression is associated with poor survival, suggesting that LRIG2 might... DisGeNET Detail
NA DisGeNET Detail
Interestingly, the adnexal SC marker Lrig1 was upregulated in SCLTs, showing that active Rac1 leads ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In oligodendroglioma, LRIG2 expression is associated with poor survival, suggesting that LRIG2 might... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Adenovirus-mediated LRIG1 expression enhances the chemosensitivity of bladder cancer cells to cispla... DisGeNET Detail
In oligodendroglioma, LRIG2 expression is associated with poor survival, suggesting that LRIG2 might... DisGeNET Detail
These results demonstrated that LRIG1 can improve chemosensitivity by modulating BCL-2 expression an... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
LRIG1, a 3p tumor suppressor, represses EGFR signaling and is a novel epigenetic silenced gene in co... DisGeNET Detail
Here, we aimed to elucidate the relationship between miR-20a, its predicted target genes leucine-ric... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In early stage breast cancer, LRIG1 copy number was recently shown to predict early and late relapse... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Adenovirus-mediated LRIG1 expression enhances the chemosensitivity of bladder cancer cells to cispla... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386526551 dbSNP
Genome
hg19
Position
chr3:66,429,221-66,551,446
Variant Type
snv
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