Annotation Detail
Information
- Associated Genes
- LRIG1
- Associated Variants
-
LRIG1 MUTATION
LRIG1 MUTATION - Associated Disease
- Skin Neoplasms
- Source Database
- DisGeNET
- Description
- Interestingly, the adnexal SC marker Lrig1 was upregulated in SCLTs, showing that active Rac1 leads to the accumulation of sebocyte precursors in the context of K14ΔNLef1-induced skin tumors.
- Pubmed
- 25659584
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs