Annotation Detail

Information
Associated Genes
LRIG1
Associated Variants
LRIG1 MUTATION
LRIG1 MUTATION
Associated Disease
Glioma
Source Database
DisGeNET
Description
MiR-20a mediated TMZ-resistance in glioblastoma cells through negatively regulating LRIG1 expression, which suggesting that miR-20a and LRIG1 would be potential therapeutic targets for glioma therapy.
Pubmed
25960225
Section of the abstract supporting the evidence
SIGNIFICANCE
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
15
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00298586059288334
Drugs