chr14:104165753:G>A Detail (hg19) (KLC1, XRCC3)

Information

Genome

Assembly Position
hg19 chr14:104,165,753-104,165,753
hg38 chr14:103,699,416-103,699,416 View the variant detail on this assembly version.

HGVS

Type Transcript Protein
RefSeq NM_182923.3:c.1624-1239G>A
NM_001130107.1:c.1782-1239G>A
Ensemble ENST00000555836.5:c.1822-1239G>A
Type Transcript Protein
RefSeq NM_001100119.1:c.722C>T NP_001093589.1:p.Thr241Met
NM_005432.3:c.722C>T NP_005423.1:p.Thr241Met
NM_001100118.1:c.722C>T NP_001093588.1:p.Thr241Met
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

JP HGVD:0.084
ToMMo:0.092
NCBN:[No Data.]
NCBN(Hondo):[No Data.]
NCBN(Ryukyu):[No Data.]
East asia ExAC:0.059

Prediction

ClinVar

Clinical Significance Benign
Review star
Show details
Links
Type Database ID Link
Gene MIM 600025 OMIM
HGNC 6387 HGNC
Ensembl ENSG00000126214 Ensembl
NCBI NCBI
Gene Cards Gene Cards
OncoKB OncoKB
Type Database ID Link
Variant TogoVar tgv52046233 TogoVar
COSMIC
MONDO
Type Database ID Link
Gene MIM 600675 OMIM
HGNC 12830 HGNC
Ensembl ENSG00000126215 Ensembl
NCBI NCBI
Gene Cards Gene Cards
OncoKB OncoKB
Type Database ID Link
Variant TogoVar tgv52046233 TogoVar
COSMIC
MONDO
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance Last evaluated Review status Condition Origin Links
risk factor 2000-10-15 no assertion criteria provided Melanoma, cutaneous malignant, susceptibility to, 6 germline Detail
Benign 2023-09-08 criteria provided, single submitter not provided germline Detail
Benign 2019-10-17 criteria provided, single submitter XRCC3-related disorder germline Detail
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.080 Carcinoma of lung Four of the variants were found to be weakly associated with lung cancer risk wi... BeFree 18990748 Detail
0.214 Malignant neoplasm of lung Four of the variants were found to be weakly associated with lung cancer risk wi... BeFree 18990748 Detail
0.044 Malignant neoplasm of lung Four of the variants were found to be weakly associated with lung cancer risk wi... BeFree 18990748 Detail
0.014 Carcinoma of lung Four of the variants were found to be weakly associated with lung cancer risk wi... BeFree 18990748 Detail
0.160 Malignant neoplasm of lung Four of the variants were found to be weakly associated with lung cancer risk wi... BeFree 18990748 Detail
0.007 Carcinoma of lung Four of the variants were found to be weakly associated with lung cancer risk wi... BeFree 18990748 Detail
0.085 Malignant neoplasm of breast Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.008 breast carcinoma Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.015 Malignant neoplasm of breast Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.011 breast carcinoma Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.002 breast carcinoma Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.009 Malignant neoplasm of breast Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.019 Malignant neoplasm of breast Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.001 breast carcinoma Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.004 breast carcinoma Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.018 breast carcinoma Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.023 Malignant neoplasm of breast Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.013 Malignant neoplasm of breast Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.002 breast carcinoma Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.098 Malignant neoplasm of breast Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... BeFree 18701435 Detail
0.021 Cancer of Head and Neck Pooling data and DNA specimens from three case-control studies in western Washin... BeFree 16030112 Detail
0.012 Cancer of Head and Neck Pooling data and DNA specimens from three case-control studies in western Washin... BeFree 16030112 Detail
0.044 Malignant neoplasm of lung We investigated the relationship between polymorphisms in two NER genes, XPC (po... BeFree 17705814 Detail
<0.001 Paroxysmal atrial tachycardia Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair gene... BeFree 16373199 Detail
<0.001 Paroxysmal atrial tachycardia Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair gene... BeFree 16373199 Detail
0.084 Carcinoma of lung We investigated the relationship between polymorphisms in two NER genes, XPC (po... BeFree 17705814 Detail
<0.001 Paroxysmal atrial tachycardia We investigated the relationship between polymorphisms in two NER genes, XPC (po... BeFree 17705814 Detail
0.006 Squamous cell carcinoma of the head and neck Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793), XRCC1 A... BeFree 21419115 Detail
0.010 colorectal carcinoma This hospital-based case-control study examined whether polymorphic DNA repair g... BeFree 15914278 Detail
<0.001 Paroxysmal atrial tachycardia Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair gene... BeFree 16373199 Detail
0.006 Paroxysmal atrial tachycardia Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair gene... BeFree 16373199 Detail
0.008 liver carcinoma In this study, we investigated whether six polymorphisms (including rs25487, rs8... BeFree 25337275 Detail
0.002 Squamous cell carcinoma of the head and neck Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793), XRCC1 A... BeFree 21419115 Detail
0.058 colorectal cancer This hospital-based case-control study examined whether polymorphic DNA repair g... BeFree 15914278 Detail
0.002 breast carcinoma In conclusion, the genetic variants evaluated are unlikely to have a substantial... BeFree 16485136 Detail
0.011 breast carcinoma In conclusion, the genetic variants evaluated are unlikely to have a substantial... BeFree 16485136 Detail
0.085 Malignant neoplasm of breast In conclusion, the genetic variants evaluated are unlikely to have a substantial... BeFree 16485136 Detail
0.080 breast carcinoma In conclusion, the genetic variants evaluated are unlikely to have a substantial... BeFree 16485136 Detail
0.480 Malignant neoplasm of breast In conclusion, the genetic variants evaluated are unlikely to have a substantial... BeFree 16485136 Detail
0.009 Malignant neoplasm of breast In conclusion, the genetic variants evaluated are unlikely to have a substantial... BeFree 16485136 Detail
0.010 Glioma Our comprehensive analysis of nine SNPs in eight genes suggests that the rs73043... BeFree 23244079 Detail
0.021 Glioma Our comprehensive analysis of nine SNPs in eight genes suggests that the rs73043... BeFree 23244079 Detail
0.003 Glioma In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... BeFree 23534771 Detail
0.021 Glioma In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... BeFree 23534771 Detail
0.008 meningioma In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... BeFree 23534771 Detail
0.008 meningioma In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... BeFree 23534771 Detail
0.010 Glioma In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... BeFree 23534771 Detail
0.003 meningioma In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... BeFree 23534771 Detail
<0.001 Non-small cell lung carcinoma The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280H... BeFree 11285194 Detail
0.010 Xeroderma Pigmentosum, Complementation Group D The purpose of the study was to evaluate the association between XRCC1 Arg399Gln... BeFree 24955348 Detail
<0.001 Nasopharyngeal carcinoma To investigate the effect of XPD Lys751Gln, XRCC1 Arg399Gln, Arg194Trp, Arg280Hi... BeFree 17630853 Detail
0.012 Non-small cell lung carcinoma The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280H... BeFree 11285194 Detail
<0.001 Lip and oral cavity carcinoma Similarly, the pseudo-haplotype of rs2040639-rs861539-rs2075685 (XRCC2-XRCC3-XRC... BeFree 18410587 Detail
0.085 Malignant neoplasm of breast Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241... BeFree 25340946 Detail
<0.001 Malignant neoplasm of mouth Similarly, the pseudo-haplotype of rs2040639-rs861539-rs2075685 (XRCC2-XRCC3-XRC... BeFree 18410587 Detail
0.098 Malignant neoplasm of breast Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241... BeFree 25340946 Detail
0.011 breast carcinoma Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241... BeFree 25340946 Detail
0.005 Non-small cell lung carcinoma The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280H... BeFree 11285194 Detail
0.003 coronary artery disease XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049)... BeFree 24315498 Detail
<0.001 coronary artery disease XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049)... BeFree 24315498 Detail
0.003 Xeroderma Pigmentosum, Complementation Group D The purpose of the study was to evaluate the association between XRCC1 Arg399Gln... BeFree 24955348 Detail
0.018 breast carcinoma Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241... BeFree 25340946 Detail
0.003 stomach carcinoma In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02)... BeFree 21347786 Detail
0.003 Malignant neoplasm of esophagus In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02)... BeFree 21347786 Detail
0.007 Malignant neoplasm of stomach In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02)... BeFree 21347786 Detail
0.127 Esophageal Neoplasms In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02)... BeFree 21347786 Detail
<0.001 esophageal carcinoma In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02)... BeFree 21347786 Detail
<0.001 Non-small cell lung carcinoma We genotyped six potentially functional single nucleotide polymorphisms (SNPs) (... BeFree 21647442 Detail
0.010 breast carcinoma Genotyping was conducted for polymorphisms in four genes involved in repair of r... BeFree 16214912 Detail
0.496 Nijmegen breakage syndrome Genotyping was conducted for polymorphisms in four genes involved in repair of r... BeFree 16214912 Detail
0.005 breast carcinoma Genotyping was conducted for polymorphisms in four genes involved in repair of r... BeFree 16214912 Detail
<0.001 Experimental Organism Basal Cell Carcinoma The data from this study show overall risk modulation of BCC by variant allele f... BeFree 16501254 Detail
0.011 breast carcinoma Genotyping was conducted for polymorphisms in four genes involved in repair of r... BeFree 16214912 Detail
0.001 Experimental Organism Basal Cell Carcinoma The data from this study show overall risk modulation of BCC by variant allele f... BeFree 16501254 Detail
0.194 Malignant neoplasm of breast Genotyping was conducted for polymorphisms in four genes involved in repair of r... BeFree 16214912 Detail
0.085 Malignant neoplasm of breast Genotyping was conducted for polymorphisms in four genes involved in repair of r... BeFree 16214912 Detail
0.036 Malignant neoplasm of breast Genotyping was conducted for polymorphisms in four genes involved in repair of r... BeFree 16214912 Detail
0.044 Malignant neoplasm of lung CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... BeFree 22525558 Detail
0.007 Carcinoma of lung CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... BeFree 22525558 Detail
0.020 Carcinoma of lung CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... BeFree 22525558 Detail
0.092 Malignant neoplasm of lung CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... BeFree 22525558 Detail
0.100 Malignant neoplasm of lung CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... BeFree 22525558 Detail
0.012 Carcinoma of lung CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... BeFree 22525558 Detail
0.018 breast carcinoma Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the O... BeFree 15066923 Detail
0.062 colorectal cancer Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the ... BeFree 15914278 Detail
0.029 colorectal cancer Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the ... BeFree 15914278 Detail
0.001 Experimental Organism Basal Cell Carcinoma The results indicate an increased risk of squamous cell carcinoma (SCC) for the ... BeFree 25218703 Detail
<0.001 Breast Cancer, Familial Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms... BeFree 17063276 Detail
0.018 breast carcinoma We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
0.013 colorectal carcinoma Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the ... BeFree 15914278 Detail
0.098 Malignant neoplasm of breast Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the O... BeFree 15066923 Detail
0.085 Malignant neoplasm of breast We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
0.001 Sporadic Breast Carcinoma Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms... BeFree 17063276 Detail
0.005 colorectal carcinoma Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the ... BeFree 15914278 Detail
0.011 breast carcinoma Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the O... BeFree 15066923 Detail
0.006 Lupus Erythematosus, Systemic In the present study, we aimed to investigate: (a) the efficiency of SLE periphe... BeFree 18852222 Detail
0.068 breast carcinoma We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
<0.001 Sporadic Breast Carcinoma Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms... BeFree 17063276 Detail
0.098 Malignant neoplasm of breast We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
0.123 Breast Cancer, Familial Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms... BeFree 17063276 Detail
<0.001 Carcinoma breast stage IV We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
0.011 breast carcinoma We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
0.015 squamous cell carcinoma The results indicate an increased risk of squamous cell carcinoma (SCC) for the ... BeFree 25218703 Detail
0.085 Malignant neoplasm of breast Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the O... BeFree 15066923 Detail
<0.001 Sporadic Breast Carcinoma Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms... BeFree 17063276 Detail
0.001 Experimental Organism Basal Cell Carcinoma The results indicate an increased risk of squamous cell carcinoma (SCC) for the ... BeFree 25218703 Detail
0.063 squamous cell carcinoma The results indicate an increased risk of squamous cell carcinoma (SCC) for the ... BeFree 25218703 Detail
0.106 Malignant neoplasm of breast We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-... BeFree 17116943 Detail
0.005 breast carcinoma Our results suggest that the 135G/C polymorphism of the RAD51, Thr241Met polymor... BeFree 25556451 Detail
<0.001 Malignant neoplasm of pharynx We investigated the effect of XRCC2 Arg(188)His and XRCC3 Thr(241)Met polymorphi... BeFree 15386379 Detail
<0.001 Malignant tumor of cervix XRCC2 R188H (rs3218536), XRCC3 T241M (rs861539) and R243H (rs77381814) single nu... BeFree 23539294 Detail
0.001 cervix carcinoma XRCC2 R188H (rs3218536), XRCC3 T241M (rs861539) and R243H (rs77381814) single nu... BeFree 23539294 Detail
<0.001 Sporadic Breast Carcinoma In conclusion, RAD51 G135C, XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms ma... BeFree 21701125 Detail
0.001 Sporadic Breast Carcinoma In conclusion, RAD51 G135C, XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms ma... BeFree 21701125 Detail
0.011 breast carcinoma Instead, significant association was identified between XRCC2 Arg188His or XRCC3... BeFree 21701125 Detail
<0.001 differentiated thyroid gland carcinoma It is recommended that Rad52 2259C&gt;T, XRCC2 R188H and XRCC3 T241M polymorphis... BeFree 24377596 Detail
0.036 Malignant neoplasm of breast Our results suggest that the 135G/C polymorphism of the RAD51, Thr241Met polymor... BeFree 25556451 Detail
<0.001 Sporadic Breast Carcinoma In conclusion, RAD51 G135C, XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms ma... BeFree 21701125 Detail
0.085 Malignant neoplasm of breast Instead, significant association was identified between XRCC2 Arg188His or XRCC3... BeFree 21701125 Detail
0.001 differentiated thyroid gland carcinoma It is recommended that Rad52 2259C&gt;T, XRCC2 R188H and XRCC3 T241M polymorphis... BeFree 24377596 Detail
0.010 Glioma No evidence of significant associations between ERCC2 rs1799793, OGG1 rs1052133,... BeFree 24500421 Detail
0.007 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.002 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.006 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.009 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.001 prostate carcinoma We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.047 Malignant neoplasm of prostate We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.007 prostate carcinoma We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.013 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.003 prostate carcinoma We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.003 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.015 Malignant neoplasm of prostate We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.004 coronary artery disease The aim of this study was to investigate the relationship between AP-endonucleas... BeFree 23368530 Detail
0.010 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.005 stomach carcinoma Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.008 Malignant neoplasm of prostate We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.012 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
0.001 prostate carcinoma We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
0.004 Malignant neoplasm of prostate We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... BeFree 19914098 Detail
<0.001 Carcinoma of bladder We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases a... BeFree 19815090 Detail
0.007 Malignant neoplasm of stomach Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R39... BeFree 20817763 Detail
<0.001 Malignant neoplasm of urinary bladder We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases a... BeFree 19815090 Detail
0.003 coronary artery disease The aim of this study was to investigate the relationship between AP-endonucleas... BeFree 23368530 Detail
0.003 Lymphoma, Follicular The following genotypes in combination with hair dye use before 1980 were associ... BeFree 25178586 Detail
0.008 Lymphoma, Follicular The following genotypes in combination with hair dye use before 1980 were associ... BeFree 25178586 Detail
0.003 Lymphoma, Follicular The following genotypes in combination with hair dye use before 1980 were associ... BeFree 25178586 Detail
0.003 Lymphoma, Follicular The following genotypes in combination with hair dye use before 1980 were associ... BeFree 25178586 Detail
0.003 Lymphoma, Follicular The following genotypes in combination with hair dye use before 1980 were associ... BeFree 25178586 Detail
0.003 Lymphoma, Follicular The following genotypes in combination with hair dye use before 1980 were associ... BeFree 25178586 Detail
0.003 Lymphoma, Follicular The following genotypes in combination with hair dye use before 1980 were associ... BeFree 25178586 Detail
0.010 Glioma This meta-analysis showed the evidence that XRCC3 Thr241Met polymorphism was ass... BeFree 23918307 Detail
0.007 Carcinoma of lung Lack of association between XRCC3 rs861539 (C &gt; T) polymorphism and lung canc... BeFree 23526128 Detail
0.005 colorectal carcinoma Association of Thr241Met polymorphism of XRCC3 gene with risk of colorectal canc... BeFree 24166604 Detail
0.008 Malignant neoplasm of prostate The association of XRCC3 Thr241Met genetic variant with risk of prostate cancer:... BeFree 25834539 Detail
0.029 colorectal cancer No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the r... BeFree 24687779 Detail
0.003 Cutaneous Melanoma Moreover, our work also points out the importance of new studies for T241M assoc... BeFree 23562721 Detail
0.012 Leukemia, Myelocytic, Acute XRCC3 Thr241Met polymorphism and risk of acute myeloid leukemia in a Romanian po... BeFree 23747401 Detail
0.004 Cancer of Head and Neck Polymorphisms of the XRCC3 C722T and the RAD51 G135C genes and the risk of head ... BeFree 20804747 Detail
0.005 colorectal carcinoma Association between the XRCC3 Thr241Met polymorphism and risk of colorectal canc... BeFree 25824748 Detail
0.085 Malignant neoplasm of breast [Our results suggested that the variability of the DNA HR repair genes XRCC3 and... GAD 20054644 Detail
0.044 Malignant neoplasm of lung XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: a meta-analysi... BeFree 20500515 Detail
0.011 breast carcinoma In summary, this meta-analysis suggests the participation of XRCC3 T241M in the ... BeFree 23562721 Detail
0.007 Carcinoma of lung On the other hand, they suggested an increased risk in individuals with the XRCC... BeFree 19031937 Detail
0.005 Carcinoma of bladder Genetic polymorphisms of XRCC3 Thr241Met (C18067T, rs861539) and bladder cancer ... BeFree 24085356 Detail
0.001 Non-small cell lung carcinoma In this report, we examined effect of the XPA -4G&gt;A, XPD Asp312Asn, Leu751Gln... BeFree 21188533 Detail
0.012 Leukemia, Myelocytic, Acute The XRCC3 Thr241Met polymorphism might be associated with risk of leukemia in AM... BeFree 24197983 Detail
0.007 Carcinoma of lung We here analyzed associations of XPD Lys751Gln, APEX1 Asp148Glu, XRCC1 Arg399Gln... BeFree 21198260 Detail
0.029 colorectal cancer XRCC3 Thr241Met gene polymorphism and risk of colorectal cancer in Kashmir: a ca... BeFree 25520078 Detail
0.002 Deglutition Disorders [Acute normal tissue reactions in head-and-neck cancer patients treated with IMR... GAD 19251090 Detail
0.005 Carcinoma of bladder XRCC3 T241M polymorphism and bladder cancer risk: a meta-analysis. BeFree 20947146 Detail
0.002 ovarian carcinoma XRCC3 Thr241Met polymorphism and ovarian cancer risk: a meta-analysis. BeFree 24254304 Detail
0.007 Carcinoma of lung In summary, this meta-analysis suggests the participation of XRCC3 T241M in the ... BeFree 23562721 Detail
0.029 colorectal cancer Association of Thr241Met polymorphism of XRCC3 gene with risk of colorectal canc... BeFree 24166604 Detail
0.012 Leukemia, Myelocytic, Acute [The genotype distribution of the XRCC1 gene indicates a role for base excision ... GAD 12393447 Detail
0.005 colorectal carcinoma No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the r... BeFree 24687779 Detail
0.044 Malignant neoplasm of lung XRCC3 Thr241Met gene polymorphisms and lung cancer risk: a meta-analysis. BeFree 23289442 Detail
0.003 Lupus Erythematosus, Systemic Association between XRCC3 Thr241Met SNP and systemic lupus erythematosus in Han ... BeFree 24395651 Detail
0.044 Malignant neoplasm of lung Meta analysis of XRCC3 Thr241Met polymorphism and lung cancer susceptibility of ... BeFree 25066399 Detail
0.085 Malignant neoplasm of breast Additionally, after stratification according to menopausal status, our results s... BeFree 20004634 Detail
0.005 colorectal carcinoma The association of the DNA repair gene XRCC3 Thr241Met polymorphism with suscept... BeFree 16271954 Detail
<0.001 Malignant tumor of cervix Association between the XRCC3 Thr241Met polymorphism and cervical cancer risk: a... BeFree 24377592 Detail
0.085 Malignant neoplasm of breast The XRCC3 Thr241Met polymorphism and breast cancer risk: a case-control study in... BeFree 17701750 Detail
0.005 Carcinoma of bladder DNA repair gene XRCC3 T241M polymorphism and bladder cancer risk in a Chinese po... BeFree 22299591 Detail
0.005 colorectal carcinoma XRCC3 Thr241Met gene polymorphism and risk of colorectal cancer in Kashmir: a ca... BeFree 25520078 Detail
<0.001 Neoplasm Metastasis However, the Thr241Met genotype of the XRCC3 polymorphism slightly increased the... BeFree 19426727 Detail
0.008 liver carcinoma XRCC3 T241M polymorphism is associated risk of hepatocellular carcinoma in the C... BeFree 23558966 Detail
0.004 Cancer of Head and Neck Association of RAD 51 135 G/C, 172 G/T and XRCC3 Thr241Met gene polymorphisms wi... BeFree 25556492 Detail
0.006 Cancer of Head and Neck Association between the XRCC3 T241M polymorphism and head and neck cancer suscep... BeFree 23244135 Detail
0.007 Carcinoma of lung XRCC3 Thr241Met gene polymorphisms and lung cancer risk: a meta-analysis. BeFree 23289442 Detail
0.005 Non-small cell lung carcinoma In this study, we analyzed the association between the XPA -4G&gt;A, XPD Asp312A... BeFree 22511383 Detail
0.029 colorectal cancer Association between the XRCC3 Thr241Met polymorphism and risk of colorectal canc... BeFree 25824748 Detail
0.005 Carcinoma of bladder XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: a meta-analysi... BeFree 20500515 Detail
0.044 Malignant neoplasm of lung XRCC3 T241M polymorphism and lung cancer risk in the Han Chinese population: a m... BeFree 25501160 Detail
0.005 Non-small cell lung carcinoma XRCC3 Thr241Met polymorphism and clinical outcomes of NSCLC patients receiving p... BeFree 23940523 Detail
0.003 Neoplasms, Second Primary [The genotype distribution of the XRCC1 gene indicates a role for base excision ... GAD 12393447 Detail
0.010 Glioma The XRCC3 Thr241Met polymorphism influences glioma risk - a meta-analysis. BeFree 23803098 Detail
0.050 Malignant neoplasm of urinary bladder Gene-environment interaction with arsenic exposure was observed in relation to b... BeFree 19429237 Detail
0.007 Carcinoma of lung Previous published data on the association between X-ray repair cross-complement... BeFree 23990458 Detail
0.007 Carcinoma of lung No significant association between the XRCC3 Thr241Met polymorphism and lung can... BeFree 23300009 Detail
0.050 Malignant neoplasm of urinary bladder In summary, this meta-analysis suggests the participation of XRCC3 T241M in the ... BeFree 23562721 Detail
0.005 colorectal carcinoma Association between XRCC3 Thr241Met polymorphism and colorectal cancer risk. BeFree 23504553 Detail
0.044 Malignant neoplasm of lung On the other hand, they suggested an increased risk in individuals with the XRCC... BeFree 19031937 Detail
0.044 Malignant neoplasm of lung Previous published data on the association between X-ray repair cross-complement... BeFree 23990458 Detail
0.002 Squamous cell carcinoma of the head and neck In conclusion our data showed that the C722T and the G135C polymorphisms of the ... BeFree 20804747 Detail
0.006 Cancer of Head and Neck Association of RAD 51 135 G/C, 172 G/T and XRCC3 Thr241Met gene polymorphisms wi... BeFree 25556492 Detail
0.008 leukemia Association of XRCC3 Thr241Met polymorphism and leukemia risk: evidence from a m... BeFree 24304418 Detail
0.005 Non-small cell lung carcinoma In this report, we examined effect of the XPA -4G&gt;A, XPD Asp312Asn, Leu751Gln... BeFree 21188533 Detail
0.010 adenocarcinoma [Acute normal tissue reactions in head-and-neck cancer patients treated with IMR... GAD 19251090 Detail
0.001 prostate carcinoma The association of XRCC3 Thr241Met genetic variant with risk of prostate cancer:... BeFree 25834539 Detail
0.011 breast carcinoma Single nucleotide polymorphism (SNP) Thr241Met in the XRCC3 gene and breast canc... BeFree 22864780 Detail
0.085 Malignant neoplasm of breast The association between polymorphisms of the RAD51-G135C, XRCC2-Arg188His and XR... BeFree 22611952 Detail
0.008 Brain Neoplasms Association between XRCC3 Thr241Met polymorphism and risk of brain tumors: a met... BeFree 24061639 Detail
0.007 Carcinoma of lung Comprehensive assessment of the association between DNA repair gene XRCC3 rs8615... BeFree 23982880 Detail
0.015 squamous cell carcinoma [Acute normal tissue reactions in head-and-neck cancer patients treated with IMR... GAD 19251090 Detail
0.050 Malignant neoplasm of urinary bladder DNA repair gene XRCC3 T241M polymorphism and bladder cancer risk in a Chinese po... BeFree 22299591 Detail
0.044 Malignant neoplasm of lung In summary, this meta-analysis suggests the participation of XRCC3 T241M in the ... BeFree 23562721 Detail
0.003 Xeroderma Pigmentosum, Complementation Group D This is the first study on DNA repair genetic polymorphisms in West Algerian pop... BeFree 24687779 Detail
0.010 Glioma Association between XRCC3 T241M polymorphism and glioma risk: a meta-analysis. BeFree 24633885 Detail
0.003 stomach carcinoma Quantitative assessment of the associations between DNA repair gene XRCC3 Thr241... BeFree 24197974 Detail
0.029 colorectal cancer The association of the DNA repair gene XRCC3 Thr241Met polymorphism with suscept... BeFree 16271954 Detail
0.085 Malignant neoplasm of breast Single nucleotide polymorphism (SNP) Thr241Met in the XRCC3 gene and breast canc... BeFree 22864780 Detail
0.002 Squamous cell carcinoma of the head and neck In conclusion our data showed that the C722T and the G135C polymorphisms of the ... BeFree 20804747 Detail
0.044 Malignant neoplasm of lung DNA repair gene XRCC3 Thr241Met polymorphisms and lung cancer risk: a meta-analy... BeFree 25794597 Detail
0.007 Malignant neoplasm of stomach XRCC3 Thr241Met polymorphism and gastric cancer susceptibility: a meta-analysis. BeFree 24315014 Detail
0.011 breast carcinoma Genetic polymorphism of XRCC3 Thr241Met and breast cancer risk: case-control stu... BeFree 17063279 Detail
0.001 cervix carcinoma Association between the XRCC3 Thr241Met polymorphism and cervical cancer risk: a... BeFree 24377592 Detail
0.003 stomach carcinoma Relationship between XRCC3 T241M polymorphism and gastric cancer risk: a meta-an... BeFree 20549576 Detail
0.011 breast carcinoma XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis. BeFree 19789975 Detail
0.003 stomach carcinoma Association of XRCC3 gene rs861539 polymorphism with gastric cancer risk: eviden... BeFree 25973083 Detail
0.007 Carcinoma of lung DNA repair gene XRCC3 Thr241Met polymorphisms and lung cancer risk: a meta-analy... BeFree 25794597 Detail
0.002 Radiodermatitis [Acute normal tissue reactions in head-and-neck cancer patients treated with IMR... GAD 19251090 Detail
0.007 Carcinoma of lung Meta analysis of XRCC3 Thr241Met polymorphism and lung cancer susceptibility of ... BeFree 25066399 Detail
0.011 breast carcinoma The association between polymorphisms of the RAD51-G135C, XRCC2-Arg188His and XR... BeFree 22611952 Detail
0.010 Glioma Association of XRCC3 Thr241Met polymorphisms and gliomas risk: evidence from a m... BeFree 23991984 Detail
0.044 Malignant neoplasm of lung Comprehensive assessment of the association between DNA repair gene XRCC3 rs8615... BeFree 23982880 Detail
0.002 Carcinogenesis In conclusion, the T allele of XRCC3 rs861539, which has an interaction with are... BeFree 24922659 Detail
0.029 colorectal cancer Association between XRCC3 Thr241Met polymorphism and colorectal cancer risk. BeFree 23504553 Detail
0.003 Malignant neoplasm of larynx Association of C722T polymorphism in XRCC3 gene with larynx cancer: a meta-analy... BeFree 24523020 Detail
0.133 melanoma Data analyses showed that none of the polymorphisms except T241M XRCC3 was assoc... BeFree 20601096 Detail
0.006 Cancer of Head and Neck Polymorphisms of the XRCC3 C722T and the RAD51 G135C genes and the risk of head ... BeFree 20804747 Detail
0.009 Malignant neoplasm of ovary XRCC3 Thr241Met polymorphism and ovarian cancer risk: a meta-analysis. BeFree 24254304 Detail
0.085 Malignant neoplasm of breast Genetic polymorphism of XRCC3 Thr241Met and breast cancer risk: case-control stu... BeFree 17063279 Detail
0.044 Malignant neoplasm of lung Lack of association between XRCC3 rs861539 (C &gt; T) polymorphism and lung canc... BeFree 23526128 Detail
0.008 leukemia Comprehensive assessment of the association between DNA repair gene XRCC3 Thr241... BeFree 24197983 Detail
0.001 Non-small cell lung carcinoma In this report, we examined effect of the XPA -4G&gt;A, XPD Asp312Asn, Leu751Gln... BeFree 21188533 Detail
0.085 Malignant neoplasm of breast Association between the XRCC3 Thr241Met polymorphism and breast cancer risk: an ... BeFree 25169497 Detail
0.135 Head and Neck Neoplasms [Acute normal tissue reactions in head-and-neck cancer patients treated with IMR... GAD 19251090 Detail
0.085 Malignant neoplasm of breast XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis. BeFree 19789975 Detail
0.005 Carcinoma of bladder Gene-environment interaction with arsenic exposure was observed in relation to b... BeFree 19429237 Detail
0.085 Malignant neoplasm of breast In summary, this meta-analysis suggests the participation of XRCC3 T241M in the ... BeFree 23562721 Detail
0.003 stomach carcinoma XRCC3 Thr241Met polymorphism and gastric cancer susceptibility: a meta-analysis. BeFree 24315014 Detail
0.007 Carcinoma of lung XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: a meta-analysi... BeFree 20500515 Detail
0.003 Cutaneous Melanoma Data analyses showed that none of the polymorphisms except T241M XRCC3 was assoc... BeFree 20601096 Detail
0.007 Carcinoma of lung XRCC3 T241M polymorphism and lung cancer risk in the Han Chinese population: a m... BeFree 25501160 Detail
0.005 Non-small cell lung carcinoma XRCC3 Thr241Met is associated with response to platinum-based chemotherapy but n... BeFree 24116196 Detail
0.044 Malignant neoplasm of lung No significant association between the XRCC3 Thr241Met polymorphism and lung can... BeFree 23300009 Detail
0.050 Malignant neoplasm of urinary bladder XRCC3 T241M polymorphism and bladder cancer risk: a meta-analysis. BeFree 20947146 Detail
0.007 Malignant neoplasm of stomach Polymorphisms of DNA repair gene XRCC3 Thr241Met and risk of gastric cancer in a... BeFree 15019159 Detail
0.044 Malignant neoplasm of lung We here analyzed associations of XPD Lys751Gln, APEX1 Asp148Glu, XRCC1 Arg399Gln... BeFree 21198260 Detail
0.005 Carcinoma of bladder In summary, this meta-analysis suggests the participation of XRCC3 T241M in the ... BeFree 23562721 Detail
0.003 Lupus Erythematosus, Systemic [Efficiency of the DNA repair and polymorphisms of the XRCC1, XRCC3 and XRCC4 DN... GAD 18852222 Detail
0.011 breast carcinoma Additionally, after stratification according to menopausal status, our results s... BeFree 20004634 Detail
0.050 Malignant neoplasm of urinary bladder Genetic polymorphisms of XRCC3 Thr241Met (C18067T, rs861539) and bladder cancer ... BeFree 24085356 Detail
0.050 Malignant neoplasm of urinary bladder XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: a meta-analysi... BeFree 20500515 Detail
0.011 breast carcinoma The XRCC3 Thr241Met polymorphism and breast cancer risk: a case-control study in... BeFree 17701750 Detail
0.003 stomach carcinoma Polymorphisms of DNA repair gene XRCC3 Thr241Met and risk of gastric cancer in a... BeFree 15019159 Detail
0.007 Malignant neoplasm of stomach Association of XRCC3 gene rs861539 polymorphism with gastric cancer risk: eviden... BeFree 25973083 Detail
0.007 Malignant neoplasm of stomach Relationship between XRCC3 T241M polymorphism and gastric cancer risk: a meta-an... BeFree 20549576 Detail
0.011 breast carcinoma Association between the XRCC3 Thr241Met polymorphism and breast cancer risk: an ... BeFree 25169497 Detail
0.008 liver carcinoma DNA repair gene XRCC3 Thr241Met polymorphism and hepatocellular carcinoma risk. BeFree 23824570 Detail
0.007 Malignant neoplasm of stomach Quantitative assessment of the associations between DNA repair gene XRCC3 Thr241... BeFree 24197974 Detail
Annotation

Annotations

DescrptionSourceLinks
NM_005432.4(XRCC3):c.722C>T (p.Thr241Met) AND Melanoma, cutaneous malignant, susceptibility to, 6 ClinVar Detail
NM_005432.4(XRCC3):c.722C>T (p.Thr241Met) AND not provided ClinVar Detail
NM_005432.4(XRCC3):c.722C>T (p.Thr241Met) AND XRCC3-related disorder ClinVar Detail
Four of the variants were found to be weakly associated with lung cancer risk with borderline signif... DisGeNET Detail
Four of the variants were found to be weakly associated with lung cancer risk with borderline signif... DisGeNET Detail
Four of the variants were found to be weakly associated with lung cancer risk with borderline signif... DisGeNET Detail
Four of the variants were found to be weakly associated with lung cancer risk with borderline signif... DisGeNET Detail
Four of the variants were found to be weakly associated with lung cancer risk with borderline signif... DisGeNET Detail
Four of the variants were found to be weakly associated with lung cancer risk with borderline signif... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... DisGeNET Detail
Pooling data and DNA specimens from three case-control studies in western Washington State, North Ca... DisGeNET Detail
Pooling data and DNA specimens from three case-control studies in western Washington State, North Ca... DisGeNET Detail
We investigated the relationship between polymorphisms in two NER genes, XPC (poly (AT) insertion/de... DisGeNET Detail
Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair genes were investigated:... DisGeNET Detail
Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair genes were investigated:... DisGeNET Detail
We investigated the relationship between polymorphisms in two NER genes, XPC (poly (AT) insertion/de... DisGeNET Detail
We investigated the relationship between polymorphisms in two NER genes, XPC (poly (AT) insertion/de... DisGeNET Detail
Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793), XRCC1 Arg194Trp (rs1799782)... DisGeNET Detail
This hospital-based case-control study examined whether polymorphic DNA repair genes: XRCC1 Arg399Gl... DisGeNET Detail
Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair genes were investigated:... DisGeNET Detail
Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair genes were investigated:... DisGeNET Detail
In this study, we investigated whether six polymorphisms (including rs25487, rs861539, rs7003908, rs... DisGeNET Detail
Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793), XRCC1 Arg194Trp (rs1799782)... DisGeNET Detail
This hospital-based case-control study examined whether polymorphic DNA repair genes: XRCC1 Arg399Gl... DisGeNET Detail
In conclusion, the genetic variants evaluated are unlikely to have a substantial overall association... DisGeNET Detail
In conclusion, the genetic variants evaluated are unlikely to have a substantial overall association... DisGeNET Detail
In conclusion, the genetic variants evaluated are unlikely to have a substantial overall association... DisGeNET Detail
In conclusion, the genetic variants evaluated are unlikely to have a substantial overall association... DisGeNET Detail
In conclusion, the genetic variants evaluated are unlikely to have a substantial overall association... DisGeNET Detail
In conclusion, the genetic variants evaluated are unlikely to have a substantial overall association... DisGeNET Detail
Our comprehensive analysis of nine SNPs in eight genes suggests that the rs730437 and rs1468727 in E... DisGeNET Detail
Our comprehensive analysis of nine SNPs in eight genes suggests that the rs730437 and rs1468727 in E... DisGeNET Detail
In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... DisGeNET Detail
In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... DisGeNET Detail
In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... DisGeNET Detail
In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... DisGeNET Detail
In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... DisGeNET Detail
In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... DisGeNET Detail
The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280His and Arg399Gln), X... DisGeNET Detail
The purpose of the study was to evaluate the association between XRCC1 Arg399Gln, Arg280His and Arg1... DisGeNET Detail
To investigate the effect of XPD Lys751Gln, XRCC1 Arg399Gln, Arg194Trp, Arg280His, and XRCC3 Thr241M... DisGeNET Detail
The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280His and Arg399Gln), X... DisGeNET Detail
Similarly, the pseudo-haplotype of rs2040639-rs861539-rs2075685 (XRCC2-XRCC3-XRCC4) and rs2040639-rs... DisGeNET Detail
Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms w... DisGeNET Detail
Similarly, the pseudo-haplotype of rs2040639-rs861539-rs2075685 (XRCC2-XRCC3-XRCC4) and rs2040639-rs... DisGeNET Detail
Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms w... DisGeNET Detail
Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms w... DisGeNET Detail
The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280His and Arg399Gln), X... DisGeNET Detail
XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049), and NQO1 (rs180056... DisGeNET Detail
XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049), and NQO1 (rs180056... DisGeNET Detail
The purpose of the study was to evaluate the association between XRCC1 Arg399Gln, Arg280His and Arg1... DisGeNET Detail
Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms w... DisGeNET Detail
In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02) in esophageal cance... DisGeNET Detail
In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02) in esophageal cance... DisGeNET Detail
In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02) in esophageal cance... DisGeNET Detail
In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02) in esophageal cance... DisGeNET Detail
In R0 resected patients, XRCC3 variants (rs861539, P = 0.04; rs861530, P = 0.02) in esophageal cance... DisGeNET Detail
We genotyped six potentially functional single nucleotide polymorphisms (SNPs) (i.e., RAD51 -135G&gt... DisGeNET Detail
Genotyping was conducted for polymorphisms in four genes involved in repair of radiation-induced DNA... DisGeNET Detail
Genotyping was conducted for polymorphisms in four genes involved in repair of radiation-induced DNA... DisGeNET Detail
Genotyping was conducted for polymorphisms in four genes involved in repair of radiation-induced DNA... DisGeNET Detail
The data from this study show overall risk modulation of BCC by variant allele for T241M polymorphis... DisGeNET Detail
Genotyping was conducted for polymorphisms in four genes involved in repair of radiation-induced DNA... DisGeNET Detail
The data from this study show overall risk modulation of BCC by variant allele for T241M polymorphis... DisGeNET Detail
Genotyping was conducted for polymorphisms in four genes involved in repair of radiation-induced DNA... DisGeNET Detail
Genotyping was conducted for polymorphisms in four genes involved in repair of radiation-induced DNA... DisGeNET Detail
Genotyping was conducted for polymorphisms in four genes involved in repair of radiation-induced DNA... DisGeNET Detail
CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... DisGeNET Detail
CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... DisGeNET Detail
CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... DisGeNET Detail
CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... DisGeNET Detail
CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... DisGeNET Detail
CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... DisGeNET Detail
Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the B... DisGeNET Detail
Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the risk of early-onset ... DisGeNET Detail
Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the risk of early-onset ... DisGeNET Detail
The results indicate an increased risk of squamous cell carcinoma (SCC) for the homozygous variant g... DisGeNET Detail
Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms as important biomar... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the risk of early-onset ... DisGeNET Detail
Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the B... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms as important biomar... DisGeNET Detail
Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the risk of early-onset ... DisGeNET Detail
Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the B... DisGeNET Detail
In the present study, we aimed to investigate: (a) the efficiency of SLE peripheral blood leucocytes... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms as important biomar... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms as important biomar... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
The results indicate an increased risk of squamous cell carcinoma (SCC) for the homozygous variant g... DisGeNET Detail
Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the B... DisGeNET Detail
Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms as important biomar... DisGeNET Detail
The results indicate an increased risk of squamous cell carcinoma (SCC) for the homozygous variant g... DisGeNET Detail
The results indicate an increased risk of squamous cell carcinoma (SCC) for the homozygous variant g... DisGeNET Detail
We retrospectively evaluated the association of SNPs in DNA repair genes, XRCC1-01 (Arg399Gln) and X... DisGeNET Detail
Our results suggest that the 135G/C polymorphism of the RAD51, Thr241Met polymorphism of XRCC3 and A... DisGeNET Detail
We investigated the effect of XRCC2 Arg(188)His and XRCC3 Thr(241)Met polymorphisms in cancer pronen... DisGeNET Detail
XRCC2 R188H (rs3218536), XRCC3 T241M (rs861539) and R243H (rs77381814) single nucleotide polymorphis... DisGeNET Detail
XRCC2 R188H (rs3218536), XRCC3 T241M (rs861539) and R243H (rs77381814) single nucleotide polymorphis... DisGeNET Detail
In conclusion, RAD51 G135C, XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms may be regarded as pre... DisGeNET Detail
In conclusion, RAD51 G135C, XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms may be regarded as pre... DisGeNET Detail
Instead, significant association was identified between XRCC2 Arg188His or XRCC3 Thr241Met polymorph... DisGeNET Detail
It is recommended that Rad52 2259C&gt;T, XRCC2 R188H and XRCC3 T241M polymorphisms should be simulta... DisGeNET Detail
Our results suggest that the 135G/C polymorphism of the RAD51, Thr241Met polymorphism of XRCC3 and A... DisGeNET Detail
In conclusion, RAD51 G135C, XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms may be regarded as pre... DisGeNET Detail
Instead, significant association was identified between XRCC2 Arg188His or XRCC3 Thr241Met polymorph... DisGeNET Detail
It is recommended that Rad52 2259C&gt;T, XRCC2 R188H and XRCC3 T241M polymorphisms should be simulta... DisGeNET Detail
No evidence of significant associations between ERCC2 rs1799793, OGG1 rs1052133, XRCC1 rs25489, XRCC... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
The aim of this study was to investigate the relationship between AP-endonuclease-1 (Asp148Glu), XRC... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... DisGeNET Detail
We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases and 250 controls to i... DisGeNET Detail
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), ... DisGeNET Detail
We undertook a case-control study of 212 urothelial bladder cancer (UBC) cases and 250 controls to i... DisGeNET Detail
The aim of this study was to investigate the relationship between AP-endonuclease-1 (Asp148Glu), XRC... DisGeNET Detail
The following genotypes in combination with hair dye use before 1980 were associated with FL risk: B... DisGeNET Detail
The following genotypes in combination with hair dye use before 1980 were associated with FL risk: B... DisGeNET Detail
The following genotypes in combination with hair dye use before 1980 were associated with FL risk: B... DisGeNET Detail
The following genotypes in combination with hair dye use before 1980 were associated with FL risk: B... DisGeNET Detail
The following genotypes in combination with hair dye use before 1980 were associated with FL risk: B... DisGeNET Detail
The following genotypes in combination with hair dye use before 1980 were associated with FL risk: B... DisGeNET Detail
The following genotypes in combination with hair dye use before 1980 were associated with FL risk: B... DisGeNET Detail
This meta-analysis showed the evidence that XRCC3 Thr241Met polymorphism was associated with a low r... DisGeNET Detail
Lack of association between XRCC3 rs861539 (C &gt; T) polymorphism and lung cancer risks: an update ... DisGeNET Detail
Association of Thr241Met polymorphism of XRCC3 gene with risk of colorectal cancer in the Polish pop... DisGeNET Detail
The association of XRCC3 Thr241Met genetic variant with risk of prostate cancer: a meta-analysis. DisGeNET Detail
No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the risk of colorectal ca... DisGeNET Detail
Moreover, our work also points out the importance of new studies for T241M association in some cance... DisGeNET Detail
XRCC3 Thr241Met polymorphism and risk of acute myeloid leukemia in a Romanian population. DisGeNET Detail
Polymorphisms of the XRCC3 C722T and the RAD51 G135C genes and the risk of head and neck cancer in a... DisGeNET Detail
Association between the XRCC3 Thr241Met polymorphism and risk of colorectal cancer: a meta analysis ... DisGeNET Detail
[Our results suggested that the variability of the DNA HR repair genes XRCC3 and RAD51D may play a r... DisGeNET Detail
XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: a meta-analysis. DisGeNET Detail
In summary, this meta-analysis suggests the participation of XRCC3 T241M in the susceptibility for b... DisGeNET Detail
On the other hand, they suggested an increased risk in individuals with the XRCC3 Thr241Met polymorp... DisGeNET Detail
Genetic polymorphisms of XRCC3 Thr241Met (C18067T, rs861539) and bladder cancer risk: a meta-analysi... DisGeNET Detail
In this report, we examined effect of the XPA -4G&gt;A, XPD Asp312Asn, Leu751Gln, hHR23B Ala249Val, ... DisGeNET Detail
The XRCC3 Thr241Met polymorphism might be associated with risk of leukemia in AML. DisGeNET Detail
We here analyzed associations of XPD Lys751Gln, APEX1 Asp148Glu, XRCC1 Arg399Gln, and XRCC3 Thr241Me... DisGeNET Detail
XRCC3 Thr241Met gene polymorphism and risk of colorectal cancer in Kashmir: a case control study. DisGeNET Detail
[Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose... DisGeNET Detail
XRCC3 T241M polymorphism and bladder cancer risk: a meta-analysis. DisGeNET Detail
XRCC3 Thr241Met polymorphism and ovarian cancer risk: a meta-analysis. DisGeNET Detail
In summary, this meta-analysis suggests the participation of XRCC3 T241M in the susceptibility for b... DisGeNET Detail
Association of Thr241Met polymorphism of XRCC3 gene with risk of colorectal cancer in the Polish pop... DisGeNET Detail
[The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the develo... DisGeNET Detail
No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the risk of colorectal ca... DisGeNET Detail
XRCC3 Thr241Met gene polymorphisms and lung cancer risk: a meta-analysis. DisGeNET Detail
Association between XRCC3 Thr241Met SNP and systemic lupus erythematosus in Han Chinese patients in ... DisGeNET Detail
Meta analysis of XRCC3 Thr241Met polymorphism and lung cancer susceptibility of populations in East ... DisGeNET Detail
Additionally, after stratification according to menopausal status, our results suggest that post-men... DisGeNET Detail
The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorecta... DisGeNET Detail
Association between the XRCC3 Thr241Met polymorphism and cervical cancer risk: a meta-analysis. DisGeNET Detail
The XRCC3 Thr241Met polymorphism and breast cancer risk: a case-control study in a Thai population. DisGeNET Detail
DNA repair gene XRCC3 T241M polymorphism and bladder cancer risk in a Chinese population. DisGeNET Detail
XRCC3 Thr241Met gene polymorphism and risk of colorectal cancer in Kashmir: a case control study. DisGeNET Detail
However, the Thr241Met genotype of the XRCC3 polymorphism slightly increased the risk of local metas... DisGeNET Detail
XRCC3 T241M polymorphism is associated risk of hepatocellular carcinoma in the Chinese. DisGeNET Detail
Association of RAD 51 135 G/C, 172 G/T and XRCC3 Thr241Met gene polymorphisms with increased risk of... DisGeNET Detail
Association between the XRCC3 T241M polymorphism and head and neck cancer susceptibility: a meta-ana... DisGeNET Detail
XRCC3 Thr241Met gene polymorphisms and lung cancer risk: a meta-analysis. DisGeNET Detail
In this study, we analyzed the association between the XPA -4G&gt;A, XPD Asp312Asn, hOGG1 Ser326Cys,... DisGeNET Detail
Association between the XRCC3 Thr241Met polymorphism and risk of colorectal cancer: a meta analysis ... DisGeNET Detail
XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: a meta-analysis. DisGeNET Detail
XRCC3 T241M polymorphism and lung cancer risk in the Han Chinese population: a meta-analysis. DisGeNET Detail
XRCC3 Thr241Met polymorphism and clinical outcomes of NSCLC patients receiving platinum-based chemot... DisGeNET Detail
[The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the develo... DisGeNET Detail
The XRCC3 Thr241Met polymorphism influences glioma risk - a meta-analysis. DisGeNET Detail
Gene-environment interaction with arsenic exposure was observed in relation to bladder cancer risk f... DisGeNET Detail
Previous published data on the association between X-ray repair cross-complementing group 3 (XRCC3) ... DisGeNET Detail
No significant association between the XRCC3 Thr241Met polymorphism and lung cancer risk: a meta-ana... DisGeNET Detail
In summary, this meta-analysis suggests the participation of XRCC3 T241M in the susceptibility for b... DisGeNET Detail
Association between XRCC3 Thr241Met polymorphism and colorectal cancer risk. DisGeNET Detail
On the other hand, they suggested an increased risk in individuals with the XRCC3 Thr241Met polymorp... DisGeNET Detail
Previous published data on the association between X-ray repair cross-complementing group 3 (XRCC3) ... DisGeNET Detail
In conclusion our data showed that the C722T and the G135C polymorphisms of the XRCC3 and the RAD51 ... DisGeNET Detail
Association of RAD 51 135 G/C, 172 G/T and XRCC3 Thr241Met gene polymorphisms with increased risk of... DisGeNET Detail
Association of XRCC3 Thr241Met polymorphism and leukemia risk: evidence from a meta-analysis. DisGeNET Detail
In this report, we examined effect of the XPA -4G&gt;A, XPD Asp312Asn, Leu751Gln, hHR23B Ala249Val, ... DisGeNET Detail
[Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose... DisGeNET Detail
The association of XRCC3 Thr241Met genetic variant with risk of prostate cancer: a meta-analysis. DisGeNET Detail
Single nucleotide polymorphism (SNP) Thr241Met in the XRCC3 gene and breast cancer risk in Polish wo... DisGeNET Detail
The association between polymorphisms of the RAD51-G135C, XRCC2-Arg188His and XRCC3-Thr241Met genes ... DisGeNET Detail
Association between XRCC3 Thr241Met polymorphism and risk of brain tumors: a meta-analysis. DisGeNET Detail
Comprehensive assessment of the association between DNA repair gene XRCC3 rs861539 C/T polymorphism ... DisGeNET Detail
[Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose... DisGeNET Detail
DNA repair gene XRCC3 T241M polymorphism and bladder cancer risk in a Chinese population. DisGeNET Detail
In summary, this meta-analysis suggests the participation of XRCC3 T241M in the susceptibility for b... DisGeNET Detail
This is the first study on DNA repair genetic polymorphisms in West Algerian population, and it sugg... DisGeNET Detail
Association between XRCC3 T241M polymorphism and glioma risk: a meta-analysis. DisGeNET Detail
Quantitative assessment of the associations between DNA repair gene XRCC3 Thr241Met polymorphism and... DisGeNET Detail
The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorecta... DisGeNET Detail
Single nucleotide polymorphism (SNP) Thr241Met in the XRCC3 gene and breast cancer risk in Polish wo... DisGeNET Detail
In conclusion our data showed that the C722T and the G135C polymorphisms of the XRCC3 and the RAD51 ... DisGeNET Detail
DNA repair gene XRCC3 Thr241Met polymorphisms and lung cancer risk: a meta-analysis. DisGeNET Detail
XRCC3 Thr241Met polymorphism and gastric cancer susceptibility: a meta-analysis. DisGeNET Detail
Genetic polymorphism of XRCC3 Thr241Met and breast cancer risk: case-control study in Korean women a... DisGeNET Detail
Association between the XRCC3 Thr241Met polymorphism and cervical cancer risk: a meta-analysis. DisGeNET Detail
Relationship between XRCC3 T241M polymorphism and gastric cancer risk: a meta-analysis. DisGeNET Detail
XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis. DisGeNET Detail
Association of XRCC3 gene rs861539 polymorphism with gastric cancer risk: evidence from a case-contr... DisGeNET Detail
DNA repair gene XRCC3 Thr241Met polymorphisms and lung cancer risk: a meta-analysis. DisGeNET Detail
[Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose... DisGeNET Detail
Meta analysis of XRCC3 Thr241Met polymorphism and lung cancer susceptibility of populations in East ... DisGeNET Detail
The association between polymorphisms of the RAD51-G135C, XRCC2-Arg188His and XRCC3-Thr241Met genes ... DisGeNET Detail
Association of XRCC3 Thr241Met polymorphisms and gliomas risk: evidence from a meta-analysis. DisGeNET Detail
Comprehensive assessment of the association between DNA repair gene XRCC3 rs861539 C/T polymorphism ... DisGeNET Detail
In conclusion, the T allele of XRCC3 rs861539, which has an interaction with areca chewing habit in ... DisGeNET Detail
Association between XRCC3 Thr241Met polymorphism and colorectal cancer risk. DisGeNET Detail
Association of C722T polymorphism in XRCC3 gene with larynx cancer: a meta-analysis. DisGeNET Detail
Data analyses showed that none of the polymorphisms except T241M XRCC3 was associated with an increa... DisGeNET Detail
Polymorphisms of the XRCC3 C722T and the RAD51 G135C genes and the risk of head and neck cancer in a... DisGeNET Detail
XRCC3 Thr241Met polymorphism and ovarian cancer risk: a meta-analysis. DisGeNET Detail
Genetic polymorphism of XRCC3 Thr241Met and breast cancer risk: case-control study in Korean women a... DisGeNET Detail
Lack of association between XRCC3 rs861539 (C &gt; T) polymorphism and lung cancer risks: an update ... DisGeNET Detail
Comprehensive assessment of the association between DNA repair gene XRCC3 Thr241Met polymorphism and... DisGeNET Detail
In this report, we examined effect of the XPA -4G&gt;A, XPD Asp312Asn, Leu751Gln, hHR23B Ala249Val, ... DisGeNET Detail
Association between the XRCC3 Thr241Met polymorphism and breast cancer risk: an updated meta-analysi... DisGeNET Detail
[Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose... DisGeNET Detail
XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis. DisGeNET Detail
Gene-environment interaction with arsenic exposure was observed in relation to bladder cancer risk f... DisGeNET Detail
In summary, this meta-analysis suggests the participation of XRCC3 T241M in the susceptibility for b... DisGeNET Detail
XRCC3 Thr241Met polymorphism and gastric cancer susceptibility: a meta-analysis. DisGeNET Detail
XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: a meta-analysis. DisGeNET Detail
Data analyses showed that none of the polymorphisms except T241M XRCC3 was associated with an increa... DisGeNET Detail
XRCC3 T241M polymorphism and lung cancer risk in the Han Chinese population: a meta-analysis. DisGeNET Detail
XRCC3 Thr241Met is associated with response to platinum-based chemotherapy but not survival in advan... DisGeNET Detail
No significant association between the XRCC3 Thr241Met polymorphism and lung cancer risk: a meta-ana... DisGeNET Detail
XRCC3 T241M polymorphism and bladder cancer risk: a meta-analysis. DisGeNET Detail
Polymorphisms of DNA repair gene XRCC3 Thr241Met and risk of gastric cancer in a Chinese population. DisGeNET Detail
We here analyzed associations of XPD Lys751Gln, APEX1 Asp148Glu, XRCC1 Arg399Gln, and XRCC3 Thr241Me... DisGeNET Detail
In summary, this meta-analysis suggests the participation of XRCC3 T241M in the susceptibility for b... DisGeNET Detail
[Efficiency of the DNA repair and polymorphisms of the XRCC1, XRCC3 and XRCC4 DNA repair genes in sy... DisGeNET Detail
Additionally, after stratification according to menopausal status, our results suggest that post-men... DisGeNET Detail
Genetic polymorphisms of XRCC3 Thr241Met (C18067T, rs861539) and bladder cancer risk: a meta-analysi... DisGeNET Detail
XRCC3 Thr241Met polymorphism with lung cancer and bladder cancer: a meta-analysis. DisGeNET Detail
The XRCC3 Thr241Met polymorphism and breast cancer risk: a case-control study in a Thai population. DisGeNET Detail
Polymorphisms of DNA repair gene XRCC3 Thr241Met and risk of gastric cancer in a Chinese population. DisGeNET Detail
Association of XRCC3 gene rs861539 polymorphism with gastric cancer risk: evidence from a case-contr... DisGeNET Detail
Relationship between XRCC3 T241M polymorphism and gastric cancer risk: a meta-analysis. DisGeNET Detail
Association between the XRCC3 Thr241Met polymorphism and breast cancer risk: an updated meta-analysi... DisGeNET Detail
DNA repair gene XRCC3 Thr241Met polymorphism and hepatocellular carcinoma risk. DisGeNET Detail
Quantitative assessment of the associations between DNA repair gene XRCC3 Thr241Met polymorphism and... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs861539 dbSNP
Genome
hg19
Position
chr14:104,165,753-104,165,753
Variant Type
snv
Reference Allele
G
Alternative Allele
A
Filtering Status (HGVD)
PASS
# of samples (HGVD)
1204
Mean of sample read depth (HGVD)
71.44
Standard deviation of sample read depth (HGVD)
36.16
Number of reference allele (HGVD)
2205
Number of alternative allele (HGVD)
203
Allele Frequency (HGVD)
0.08430232558139535
Gene Symbol (HGVD)
XRCC3
ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
PASS
Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
rs861539
Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
0.0922
Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
1545
Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
16760
East Asian Chromosome Counts (ExAC)
7782
East Asian Allele Counts (ExAC)
456
East Asian Heterozygous Counts (ExAC)
440
East Asian Homozygous Counts (ExAC)
8
East Asian Allele Frequency (ExAC)
0.058596761757902856
Chromosome Counts in All Race (ExAC)
112294
Allele Counts in All Race (ExAC)
34532
Heterozygous Counts in All Race (ExAC)
23030
Homozygous Counts in All Race (ExAC)
5751
Allele Frequency in All Race (ExAC)
0.307514203786489
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