chrX:114584078:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chrX:113,818,551-114,144,624 |
| hg38 | chrX:114,584,078-114,910,061 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | Cardiovascular Diseases | NA | BeFree | Detail | |
| 0.010 | Mental Depression | Activity of the x-linked serotonin 5-HTR2C receptor has also been shown to be as... | BeFree,GAD | 25514629 | Detail |
| 0.002 | depressive disorder | Activity of the x-linked serotonin 5-HTR2C receptor has also been shown to be as... | BeFree | 25514629 | Detail |
| <0.001 | Diabetes | NA | BeFree | Detail | |
| <0.001 | diabetes mellitus | NA | BeFree | Detail | |
| 0.086 | Diabetes Mellitus, Non-Insulin-Dependent | NA | BeFree,GAD,MGD | Detail | |
| <0.001 | Drug abuse | NA | BeFree | Detail | |
| <0.001 | Dyskinetic syndrome | NA | BeFree | Detail | |
| 0.003 | Dyskinesia, Drug-Induced | NA | BeFree,GAD | Detail | |
| <0.001 | Eating Disorders | NA | BeFree | Detail | |
| 0.002 | Endocrine System Diseases | NA | GAD | Detail | |
| 0.002 | Epilepsy, Temporal Lobe | NA | GAD | Detail | |
| <0.001 | Extrapyramidal Disorders | NA | BeFree | Detail | |
| 0.002 | Fatigue | NA | GAD | Detail | |
| 0.002 | chronic fatigue syndrome | NA | GAD | Detail | |
| <0.001 | Atrial Septal Defects | NA | BeFree | Detail | |
| <0.001 | hyperinsulinism | NA | BeFree | Detail | |
| 0.080 | Liver Neoplasms, Experimental | NA | RGD | Detail | |
| <0.001 | Muscle Rigidity | NA | BeFree | Detail | |
| <0.001 | Neuralgia | NA | BeFree | Detail | |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| 0.146 | obesity | NA | BeFree,CTD_human,GAD | Detail | |
| 0.080 | Pain | NA | BeFree,RGD | Detail | |
| 0.002 | Parkinson disease | NA | GAD | Detail | |
| 0.081 | Prader-Willi syndrome | NA | BeFree,MGD | Detail | |
| 0.003 | Psychotic Disorders | NA | BeFree,GAD | Detail | |
| 0.002 | Puerperal Disorders | NA | GAD | Detail | |
| 0.038 | schizophrenia | We investigated the associations of the LEP-2548A/G and HTR2C-759C/T polymorphis... | BeFree,GAD,LHGDN | 25304226 | Detail |
| <0.001 | Seizures | NA | BeFree | Detail | |
| <0.001 | Stress, Psychological | A putatively functional polymorphism in the HTR2C gene is associated with depres... | BeFree | 25514629 | Detail |
| <0.001 | substance dependence | NA | BeFree | Detail | |
| 0.122 | Substance Withdrawal Syndrome | NA | CTD_human,GAD | Detail | |
| 0.003 | Gilles de la Tourette syndrome | NA | BeFree,GAD | Detail | |
| 0.003 | tuberous sclerosis | NA | BeFree,GAD | Detail | |
| 0.004 | Unipolar Depression | NA | BeFree,GAD | Detail | |
| 0.151 | Weight Gain | NA | CTD_human,GAD | Detail | |
| 0.003 | seasonal affective disorder | NA | BeFree,GAD | Detail | |
| <0.001 | Self-Injurious Behavior | NA | BeFree | Detail | |
| <0.001 | Agitation | NA | BeFree | Detail | |
| 0.005 | Alcohol abuse | NA | GAD | Detail | |
| <0.001 | Depressive Symptoms | A putatively functional polymorphism in the HTR2C gene is associated with depres... | BeFree | 25514629 | Detail |
| <0.001 | Emotional Stress | NA | BeFree | Detail | |
| 0.006 | Migraine Disorders | NA | BeFree,GAD | Detail | |
| <0.001 | polyneuropathy | NA | BeFree | Detail | |
| 0.006 | lingual-facial-buccal dyskinesia | NA | BeFree,GAD | Detail | |
| <0.001 | Recurrent major depressive episodes | NA | BeFree | Detail | |
| 0.009 | migraine with aura | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | Akathisia, Drug-Induced | NA | GAD | Detail | |
| <0.001 | Chronic schizophrenia | Polymorphisms of the leptin and HTR2C genes and clozapine-induced weight change ... | BeFree | 25304226 | Detail |
| <0.001 | Psychological symptom | NA | BeFree | Detail | |
| <0.001 | Bradykinesia | NA | BeFree | Detail | |
| <0.001 | Hallucinosis | NA | BeFree | Detail | |
| 0.005 | Personality Traits | NA | GAD | Detail | |
| <0.001 | Resting Tremor | NA | BeFree | Detail | |
| 0.080 | Substance-Related Disorders | NA | RGD | Detail | |
| 0.002 | Physiological Sexual Disorders | NA | GAD | Detail | |
| <0.001 | Parkinsonian Disorders | NA | BeFree | Detail | |
| <0.001 | major affective disorder | NA | BeFree | Detail | |
| <0.001 | Psychotic episode | NA | BeFree | Detail | |
| <0.001 | Drug-induced depressive state | NA | BeFree | Detail | |
| <0.001 | Nonorganic psychosis | NA | BeFree | Detail | |
| 0.120 | Hyperactive behavior | NA | CTD_human | Detail | |
| <0.001 | Peripheral neuropathic pain | NA | BeFree | Detail | |
| 0.002 | body mass | NA | GAD | Detail | |
| 0.005 | Sleep Apnea, Obstructive | NA | BeFree,GAD | Detail | |
| <0.001 | Pervasive Development Disorder | NA | BeFree | Detail | |
| 0.126 | Metabolic syndrome X | HTR2C polymorphisms, olanzapine-induced weight gain and antipsychotic-induced me... | BeFree,CTD_human,GAD | 25152019 | Detail |
| 0.005 | Sleep Apnea, Obstructive | Genotypes and allele frequencies of 102T/C polymorphism of the HTR2A and 796G/C ... | BeFree | 16258205 | Detail |
| 0.006 | lingual-facial-buccal dyskinesia | The 9Gly-variant of the dopamine D3 receptor, the 102C-variant, but not the His4... | BeFree | 15861931 | Detail |
| 0.006 | Tardive Dyskinesia | The 9Gly-variant of the dopamine D3 receptor, the 102C-variant, but not the His4... | BeFree | 15861931 | Detail |
| <0.001 | cocaine dependence | Our translational findings suggest that the functional status of the 5-HT2CR sys... | BeFree | 24618688 | Detail |
| 0.006 | Tardive Dyskinesia | NA | BeFree,GAD | Detail | |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Substance abuse problem | NA | BeFree | Detail | |
| <0.001 | metabolic disturbance | More association studies are needed to further elucidate association of differen... | BeFree | 25152019 | Detail |
| 0.002 | Sleep Disorders | NA | GAD | Detail | |
| <0.001 | Psychotic symptom | NA | BeFree | Detail | |
| 0.008 | attention deficit hyperactivity disorder | NA | BeFree,GAD | Detail | |
| 0.089 | major depressive disorder | NA | BeFree,GAD,RGD | Detail | |
| <0.001 | drug dependence | NA | BeFree | Detail | |
| <0.001 | Autism Spectrum Disorders | NA | BeFree | Detail | |
| <0.001 | Depression and Suicide | NA | BeFree | Detail | |
| 0.003 | MAJOR AFFECTIVE DISORDER 2 | NA | BeFree,GAD | Detail | |
| 0.003 | MAJOR AFFECTIVE DISORDER 1 | NA | BeFree,GAD | Detail | |
| 0.003 | MAJOR AFFECTIVE DISORDER 4 | NA | BeFree,GAD | Detail | |
| 0.003 | MAJOR AFFECTIVE DISORDER 5 | NA | BeFree,GAD | Detail | |
| 0.003 | MAJOR AFFECTIVE DISORDER 6 | NA | BeFree,GAD | Detail | |
| 0.003 | bulimia nervosa | NA | BeFree,LHGDN | Detail | |
| 0.003 | Major affective disorder 7 | NA | BeFree,GAD | Detail | |
| 0.003 | MAJOR AFFECTIVE DISORDER 8 | NA | BeFree,GAD | Detail | |
| 0.003 | MAJOR AFFECTIVE DISORDER 9 | NA | BeFree,GAD | Detail | |
| 0.002 | Weight Loss Adverse Event | NA | GAD | Detail | |
| 0.031 | Weight Gain Adverse Event | NA | GAD | Detail | |
| 0.004 | Alcoholic Intoxication, Chronic | NA | BeFree,GAD | Detail | |
| 0.007 | Alzheimer's disease | NA | GAD,LHGDN | Detail | |
| <0.001 | Anorexia | NA | BeFree | Detail | |
| 0.006 | anorexia nervosa | NA | BeFree,GAD,LHGDN | Detail | |
| 0.084 | Anxiety Disorders | NA | BeFree,GAD,RGD | Detail | |
| 0.005 | As If Personality | NA | GAD | Detail | |
| 0.005 | autistic disorder | NA | BeFree,GAD | Detail | |
| 0.002 | Basal Ganglia Diseases | NA | GAD | Detail | |
| 0.002 | Mental disorders | Joint effect of ADARB1 gene, HTR2C gene and stressful life events on suicide att... | BeFree | 25732952 | Detail |
| 0.014 | bipolar disorder | NA | BeFree,GAD | Detail | |
| <0.001 | borderline personality disorder | NA | BeFree | Detail | |
| <0.001 | bronchopulmonary dysplasia | NA | BeFree | Detail | |
| 0.002 | Bulimia | NA | GAD | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| Activity of the x-linked serotonin 5-HTR2C receptor has also been shown to be associated with depres... | DisGeNET | Detail |
| Activity of the x-linked serotonin 5-HTR2C receptor has also been shown to be associated with depres... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We investigated the associations of the LEP-2548A/G and HTR2C-759C/T polymorphisms with long-term cl... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in whi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in whi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Polymorphisms of the leptin and HTR2C genes and clozapine-induced weight change and baseline BMI in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| HTR2C polymorphisms, olanzapine-induced weight gain and antipsychotic-induced metabolic syndrome in ... | DisGeNET | Detail |
| Genotypes and allele frequencies of 102T/C polymorphism of the HTR2A and 796G/C polymorphism of the ... | DisGeNET | Detail |
| The 9Gly-variant of the dopamine D3 receptor, the 102C-variant, but not the His452Tyr polymorphism o... | DisGeNET | Detail |
| The 9Gly-variant of the dopamine D3 receptor, the 102C-variant, but not the His452Tyr polymorphism o... | DisGeNET | Detail |
| Our translational findings suggest that the functional status of the 5-HT2CR system is a mechanistic... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| More association studies are needed to further elucidate association of different HTR2C polymorphism... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Joint effect of ADARB1 gene, HTR2C gene and stressful life events on suicide attempt risk in patient... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386602276 dbSNP
- Genome
- hg38
- Position
- chrX:114,584,078-114,910,061
- Variant Type
- snv
Genome browser