chr11:61792911:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr11:61,560,383-61,564,710 |
| hg38 | chr11:61,792,911-61,797,238 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | Cockayne syndrome | NA | BeFree | Detail | |
| <0.001 | colorectal carcinoma | It is also thought that the product of the APC gene can modulate base excision r... | BeFree | 26334567 | Detail |
| 0.120 | Colorectal Neoplasms | NA | CTD_human | Detail | |
| <0.001 | Coronary Arteriosclerosis | NA | BeFree | Detail | |
| <0.001 | Coronary heart disease | NA | BeFree | Detail | |
| <0.001 | Glioma | NA | BeFree | Detail | |
| 0.002 | Graft-vs-Host Disease | NA | GAD | Detail | |
| 0.002 | Head and Neck Neoplasms | NA | GAD | Detail | |
| <0.001 | congenital heart defects | NA | BeFree | Detail | |
| 0.003 | Huntington disease | NA | BeFree,GAD | Detail | |
| <0.001 | Congenital hydrocephalus | NA | BeFree | Detail | |
| 0.003 | Lung Neoplasms | NA | BeFree,LHGDN | Detail | |
| 0.003 | Lupus Erythematosus, Systemic | NA | BeFree,GAD | Detail | |
| 0.002 | multiple sclerosis | NA | GAD | Detail | |
| <0.001 | Myotonic dystrophy | NA | BeFree | Detail | |
| <0.001 | Neoplasm Metastasis | NA | BeFree | Detail | |
| 0.002 | Neoplasm Recurrence, Local | NA | GAD | Detail | |
| <0.001 | ovarian carcinoma | Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a ... | BeFree | 24880630 | Detail |
| <0.001 | Adenomatous Polyposis Coli | NA | BeFree | Detail | |
| <0.001 | Werner syndrome | NA | BeFree | Detail | |
| 0.002 | Neoplasms, Second Primary | NA | GAD | Detail | |
| <0.001 | Tumor Progression | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of lung | NA | BeFree,GAD | Detail | |
| <0.001 | Xeroderma pigmentosum, group G | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of prostate | NA | BeFree | Detail | |
| 0.002 | Hematologic Neoplasms | NA | GAD | Detail | |
| <0.001 | Congenital Myotonic Dystrophy | NA | BeFree | Detail | |
| <0.001 | endometrial carcinoma | NA | BeFree | Detail | |
| 0.001 | Carcinogenesis | NA | BeFree | Detail | |
| <0.001 | prostate carcinoma | NA | BeFree | Detail | |
| <0.001 | Epithelial ovarian cancer | We conclude that FEN1 is a promising biomarker in breast and ovarian epithelial ... | BeFree | 24880630 | Detail |
| 0.002 | breast carcinoma | We identified a FEN1 germline mutation that changed residue E359 to K in a patie... | BeFree | 24608430 | Detail |
| 0.002 | breast carcinoma | FEN1 mRNA overexpression is associated with poor breast cancer specific survival... | BeFree | 24880630 | Detail |
| 0.002 | breast carcinoma | Key base excision repair (BER) proteins, including XRCC1, APE1, SMUG1, and FEN1,... | BeFree | 25111287 | Detail |
| 0.002 | breast carcinoma | YY1 suppresses FEN1 over-expression and drug resistance in breast cancer. | BeFree | 25885449 | Detail |
| 0.001 | Carcinoma of lung | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of gastrointestinal tract | NA | BeFree | Detail | |
| 0.007 | Malignant neoplasm of breast | rs1130409/T1865G (APEX1), rs1799782/T22142C (XRCC1), rs25487/G23990A (XRCC1), rs... | BeFree | 18669164 | Detail |
| 0.002 | breast carcinoma | rs1130409/T1865G (APEX1), rs1799782/T22142C (XRCC1), rs25487/G23990A (XRCC1), rs... | BeFree | 18669164 | Detail |
| <0.001 | Malignant neoplasm of ovary | Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a ... | BeFree | 24880630 | Detail |
| <0.001 | Adenoma of large intestine | NA | BeFree | Detail | |
| <0.001 | colorectal cancer | It is also thought that the product of the APC gene can modulate base excision r... | BeFree | 26334567 | Detail |
| 0.003 | coronary artery disease | NA | BeFree,GAD | Detail | |
| <0.001 | liver carcinoma | NA | BeFree | Detail | |
| <0.001 | Early-Stage Breast Carcinoma | To test this hypothesis, we investigated 1406 ER(+) early-stage breast cancers w... | BeFree | 25111287 | Detail |
| 0.007 | Malignant neoplasm of breast | We identified a FEN1 germline mutation that changed residue E359 to K in a patie... | BeFree,GAD | 24608430 | Detail |
| 0.007 | Malignant neoplasm of breast | FEN1 mRNA overexpression is associated with poor breast cancer specific survival... | BeFree,GAD | 24880630 | Detail |
| 0.007 | Malignant neoplasm of breast | Key base excision repair (BER) proteins, including XRCC1, APE1, SMUG1, and FEN1,... | BeFree,GAD | 25111287 | Detail |
| 0.007 | Malignant neoplasm of breast | YY1 suppresses FEN1 over-expression and drug resistance in breast cancer. | BeFree,GAD | 25885449 | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| It is also thought that the product of the APC gene can modulate base excision repair (BER) pathway ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in bre... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We conclude that FEN1 is a promising biomarker in breast and ovarian epithelial cancer. | DisGeNET | Detail |
| We identified a FEN1 germline mutation that changed residue E359 to K in a patient whose family had ... | DisGeNET | Detail |
| FEN1 mRNA overexpression is associated with poor breast cancer specific survival in univariate (p = ... | DisGeNET | Detail |
| Key base excision repair (BER) proteins, including XRCC1, APE1, SMUG1, and FEN1, were independently ... | DisGeNET | Detail |
| YY1 suppresses FEN1 over-expression and drug resistance in breast cancer. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| rs1130409/T1865G (APEX1), rs1799782/T22142C (XRCC1), rs25487/G23990A (XRCC1), rs4989588/T3337A (FEN1... | DisGeNET | Detail |
| rs1130409/T1865G (APEX1), rs1799782/T22142C (XRCC1), rs25487/G23990A (XRCC1), rs4989588/T3337A (FEN1... | DisGeNET | Detail |
| Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in bre... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| It is also thought that the product of the APC gene can modulate base excision repair (BER) pathway ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To test this hypothesis, we investigated 1406 ER(+) early-stage breast cancers with 20 years' long-t... | DisGeNET | Detail |
| We identified a FEN1 germline mutation that changed residue E359 to K in a patient whose family had ... | DisGeNET | Detail |
| FEN1 mRNA overexpression is associated with poor breast cancer specific survival in univariate (p = ... | DisGeNET | Detail |
| Key base excision repair (BER) proteins, including XRCC1, APE1, SMUG1, and FEN1, were independently ... | DisGeNET | Detail |
| YY1 suppresses FEN1 over-expression and drug resistance in breast cancer. | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs4989586 dbSNP
- Genome
- hg38
- Position
- chr11:61,792,911-61,797,238
- Variant Type
- snv
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