chr19:43553422:G>A Detail (hg38) (XRCC1)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr19:44,057,574-44,057,574 View the variant detail on this assembly version. |
| hg38 | chr19:43,553,422-43,553,422 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
| RefSeq | NM_006297.2:c.487C>T | NP_006288.2:p.Arg163Trp |
| Ensemble | ENST00000262887.10:c.580C>T | ENST00000262887.10:p.Arg194Trp |
| ENST00000543982.5:c.487C>T | ENST00000543982.5:p.Arg163Trp |
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
| JP | HGVD:0.313 |
| ToMMo:0.312 | |
| NCBN:[No Data.] | |
| NCBN(Hondo):[No Data.] | |
| NCBN(Ryukyu):[No Data.] | |
| East asia | ExAC:0.307 |
Prediction
ClinVar
| Clinical Significance |
Benign
|
| Review star |  |
| Show details | |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
CIViC
| Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| lung non-small cell carcinoma | Gemcitabine,Vinorelbine,Docetaxel | B |
Predictive
|
Supports
|
Sensitivity/Response | Rare Germline | 4 | 19157633 | Detail |
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.003 | Nasopharyngeal carcinoma | The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... | BeFree | 25481674 | Detail |
| 0.261 | Nasopharyngeal carcinoma | The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... | BeFree | 25481674 | Detail |
| 0.002 | Nasopharyngeal carcinoma | The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... | BeFree | 25481674 | Detail |
| 0.123 | Nasopharyngeal carcinoma | The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... | BeFree | 25481674 | Detail |
| 0.085 | Malignant neoplasm of breast | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.008 | breast carcinoma | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.015 | Malignant neoplasm of breast | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.011 | breast carcinoma | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| <0.001 | Triple Negative Breast Neoplasms | Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R41... | BeFree | 25023197 | Detail |
| 0.002 | breast carcinoma | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.009 | Malignant neoplasm of breast | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.019 | Malignant neoplasm of breast | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.001 | breast carcinoma | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.004 | breast carcinoma | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| <0.001 | Triple Negative Breast Neoplasms | Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R41... | BeFree | 25023197 | Detail |
| 0.018 | breast carcinoma | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| <0.001 | Triple Negative Breast Neoplasms | Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R41... | BeFree | 25023197 | Detail |
| 0.023 | Malignant neoplasm of breast | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.013 | Malignant neoplasm of breast | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| 0.002 | breast carcinoma | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| <0.001 | Triple Negative Breast Neoplasms | Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R41... | BeFree | 25023197 | Detail |
| 0.098 | Malignant neoplasm of breast | Using data/samples collected from the first 752 Caucasians and 141 African-Ameri... | BeFree | 18701435 | Detail |
| <0.001 | Triple Negative Breast Neoplasms | Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R41... | BeFree | 25023197 | Detail |
| <0.001 | Triple Negative Breast Neoplasms | Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R41... | BeFree | 25023197 | Detail |
| <0.001 | Lymphoma, Large-Cell, Follicular | Compared to those with BMI <25, women with BMI ≥25 had significantly increase... | BeFree | 23619945 | Detail |
| 0.005 | Lymphoma, Non-Hodgkin | Compared to those with BMI <25, women with BMI ≥25 had significantly increase... | BeFree | 23619945 | Detail |
| <0.001 | Paroxysmal atrial tachycardia | Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair gene... | BeFree | 16373199 | Detail |
| 0.084 | Malignant neoplasm of breast | Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and A... | BeFree | 16319991 | Detail |
| 0.008 | Lymphoma, Non-Hodgkin | Compared to those with BMI <25, women with BMI ≥25 had significantly increase... | BeFree | 23619945 | Detail |
| <0.001 | Lymphoma, Large-Cell, Follicular | Compared to those with BMI <25, women with BMI ≥25 had significantly increase... | BeFree | 23619945 | Detail |
| <0.001 | Paroxysmal atrial tachycardia | Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair gene... | BeFree | 16373199 | Detail |
| 0.006 | Squamous cell carcinoma of the head and neck | Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793), XRCC1 A... | BeFree | 21419115 | Detail |
| <0.001 | Lymphoma, Large-Cell, Follicular | Compared to those with BMI <25, women with BMI ≥25 had significantly increase... | BeFree | 23619945 | Detail |
| 0.013 | Lymphoma, Non-Hodgkin | Compared to those with BMI <25, women with BMI ≥25 had significantly increase... | BeFree | 23619945 | Detail |
| 0.018 | breast carcinoma | Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and A... | BeFree | 16319991 | Detail |
| <0.001 | Paroxysmal atrial tachycardia | Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair gene... | BeFree | 16373199 | Detail |
| 0.008 | breast carcinoma | Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and A... | BeFree | 16319991 | Detail |
| 0.098 | Malignant neoplasm of breast | Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and A... | BeFree | 16319991 | Detail |
| 0.006 | Paroxysmal atrial tachycardia | Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair gene... | BeFree | 16373199 | Detail |
| 0.002 | Squamous cell carcinoma of the head and neck | Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793), XRCC1 A... | BeFree | 21419115 | Detail |
| 0.006 | Lymphoma, Non-Hodgkin | Compared to those with BMI <25, women with BMI ≥25 had significantly increase... | BeFree | 23619945 | Detail |
| <0.001 | Lymphoma, Large-Cell, Follicular | Compared to those with BMI <25, women with BMI ≥25 had significantly increase... | BeFree | 23619945 | Detail |
| 0.010 | Glioma | Our comprehensive analysis of nine SNPs in eight genes suggests that the rs73043... | BeFree | 23244079 | Detail |
| 0.021 | Glioma | Our comprehensive analysis of nine SNPs in eight genes suggests that the rs73043... | BeFree | 23244079 | Detail |
| <0.001 | Xeroderma Pigmentosum, Complementation Group D | The germline polymorphisms studied were thymidylate synthase, (VNTR/5'UTR, 2R G&... | BeFree | 21570215 | Detail |
| 0.010 | Xeroderma Pigmentosum, Complementation Group D | The germline polymorphisms studied were thymidylate synthase, (VNTR/5'UTR, 2R G&... | BeFree | 21570215 | Detail |
| <0.001 | Xeroderma Pigmentosum, Complementation Group D | The germline polymorphisms studied were thymidylate synthase, (VNTR/5'UTR, 2R G&... | BeFree | 21570215 | Detail |
| <0.001 | Xeroderma Pigmentosum, Complementation Group D | The germline polymorphisms studied were thymidylate synthase, (VNTR/5'UTR, 2R G&... | BeFree | 21570215 | Detail |
| 0.003 | Glioma | In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... | BeFree | 23534771 | Detail |
| 0.021 | Glioma | In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... | BeFree | 23534771 | Detail |
| 0.008 | meningioma | In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... | BeFree | 23534771 | Detail |
| 0.008 | meningioma | In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... | BeFree | 23534771 | Detail |
| 0.010 | Glioma | In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... | BeFree | 23534771 | Detail |
| 0.003 | meningioma | In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 ... | BeFree | 23534771 | Detail |
| <0.001 | Non-small cell lung carcinoma | The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280H... | BeFree | 11285194 | Detail |
| 0.010 | Xeroderma Pigmentosum, Complementation Group D | The purpose of the study was to evaluate the association between XRCC1 Arg399Gln... | BeFree | 24955348 | Detail |
| 0.018 | Malignant neoplasm of stomach | XRCC1 genetic polymorphism Arg339Gln, Arg194Trp, Arg280His and gastric cancer ri... | BeFree | 25335737 | Detail |
| <0.001 | Exanthema | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.135 | adenocarcinoma | The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and b... | BeFree | 15840879 | Detail |
| 0.007 | prostate carcinoma | This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms... | BeFree | 17196815 | Detail |
| <0.001 | Nasopharyngeal carcinoma | To investigate the effect of XPD Lys751Gln, XRCC1 Arg399Gln, Arg194Trp, Arg280Hi... | BeFree | 17630853 | Detail |
| 0.012 | Non-small cell lung carcinoma | The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280H... | BeFree | 11285194 | Detail |
| 0.006 | Carcinoma, Transitional Cell | XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are... | BeFree | 25018058 | Detail |
| 0.021 | Glioma | Decreased glioma risk was observed with the XRCC1 rs1799782 variant (P(trend) .0... | BeFree | 20150366 | Detail |
| 0.021 | Cancer of Head and Neck | The XRCC1 Arg194Trp and Arg280His polymorphisms in head and neck cancer suscepti... | BeFree | 25062722 | Detail |
| <0.001 | Lip and oral cavity carcinoma | Similarly, the pseudo-haplotype of rs2040639-rs861539-rs2075685 (XRCC2-XRCC3-XRC... | BeFree | 18410587 | Detail |
| 0.006 | Squamous cell carcinoma of the head and neck | In conclusion, the result from our study provides additional evidence of an asso... | BeFree | 15252855 | Detail |
| <0.001 | Malignant tumor of colon | The present meta-analysis suggests that the XRCC1 Arg194Trp polymorphism may mod... | BeFree | 23857281 | Detail |
| 0.085 | Malignant neoplasm of breast | Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241... | BeFree | 25340946 | Detail |
| 0.126 | Neoplasm Metastasis | Results showed that Trp/Trp genotype of XRCC1 Arg194Trp and AA genotype of ERCC1... | BeFree | 25690281 | Detail |
| <0.001 | Polyp of large intestine | The purpose of this study was to examine the association of two genetic polymorp... | BeFree | 21612998 | Detail |
| 0.038 | Esophageal Neoplasms | Two non-synonymous polymorphisms Arg194Trp and Arg399Gln in the DNA-base excisio... | BeFree | 19444915 | Detail |
| 0.072 | Malignant neoplasm of lung | The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and b... | BeFree | 15840879 | Detail |
| 0.013 | Carcinoma of lung | The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and b... | BeFree | 15840879 | Detail |
| 0.008 | stomach carcinoma | XRCC1 genetic polymorphism Arg339Gln, Arg194Trp, Arg280His and gastric cancer ri... | BeFree | 25335737 | Detail |
| 0.003 | Nasopharyngeal carcinoma | In addition, our work also points out the importance of new studies for Arg194Tr... | BeFree | 25064613 | Detail |
| 0.006 | Lupus Erythematosus, Systemic | XRCC1 Arg399Gln and Arg194Trp polymorphisms and risk of systemic lupus erythemat... | BeFree | 24971336 | Detail |
| <0.001 | Malignant neoplasm of mouth | Similarly, the pseudo-haplotype of rs2040639-rs861539-rs2075685 (XRCC2-XRCC3-XRC... | BeFree | 18410587 | Detail |
| 0.002 | esophageal carcinoma | Two non-synonymous polymorphisms Arg194Trp and Arg399Gln in the DNA-base excisio... | BeFree | 19444915 | Detail |
| 0.098 | Malignant neoplasm of breast | In addition, breast cancer risk was significantly associated with an increasing ... | BeFree | 14652281 | Detail |
| 0.005 | Cervical Intraepithelial Neoplasia | To evaluate contribution of single nucleotide polymorphisms (SNPs) of X-ray repa... | BeFree | 17504380 | Detail |
| <0.001 | cholangiocarcinoma | We genotyped five non-synonymous single-nucleotide polymorphisms of three genes,... | BeFree | 24049014 | Detail |
| <0.001 | Urothelial Carcinoma | XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are... | BeFree | 25018058 | Detail |
| 0.047 | Malignant neoplasm of prostate | XRCC1 Arg399Gln and Arg194Trp polymorphisms in prostate cancer risk: a meta-anal... | BeFree | 21647176 | Detail |
| 0.007 | prostate carcinoma | XRCC1 Arg399Gln and Arg194Trp polymorphisms in prostate cancer risk: a meta-anal... | BeFree | 21647176 | Detail |
| 0.020 | Carcinoma of lung | Homozygous Trp/Trp variant genotype of XRCC1 Arg194Trp polymorphism could increa... | BeFree | 20975374 | Detail |
| 0.008 | Carcinoma of bladder | XRCC1 Arg194Trp and Arg280His polymorphisms in bladder cancer susceptibility: a ... | BeFree | 24266849 | Detail |
| 0.098 | Malignant neoplasm of breast | Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241... | BeFree | 25340946 | Detail |
| <0.001 | Cancer of Nasopharynx | In addition, our work also points out the importance of new studies for Arg194Tr... | BeFree | 25064613 | Detail |
| 0.001 | Lip and oral cavity carcinoma | XRCC1 Arg194Trp polymorphism is associated with oral cancer risk: evidence from ... | BeFree | 23681796 | Detail |
| 0.047 | Malignant neoplasm of prostate | In conclusion, the meta-analysis suggests that there is no obvious association b... | BeFree | 24492938 | Detail |
| 0.018 | breast carcinoma | The present study aimed to investigate the association between Arg194Trp (XRCC1)... | BeFree | 25862854 | Detail |
| 0.100 | Malignant neoplasm of lung | Therefore, this meta-analysis suggests that XRCC1 Arg194Trp polymorphism is asso... | BeFree | 23653378 | Detail |
| <0.001 | Xeroderma pigmentosum, group G | Our study showed that the polymorphic status of XRCC1 194Arg/Trp might be a pred... | BeFree | 19157633 | Detail |
| <0.001 | Tumor Progression | Our findings demonstrated that the genetic variant Arg280His in XRCC1 may contri... | BeFree | 23425027 | Detail |
| 0.008 | Leukemia, Myelocytic, Acute | XRCC1 Arg194Trp and Arg399Gln polymorphisms are significantly associated with sh... | BeFree | 23662987 | Detail |
| <0.001 | Spots on skin | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.020 | Carcinoma of lung | The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and b... | BeFree | 15840879 | Detail |
| 0.028 | Malignant neoplasm of esophagus | XRCC1 Arg399Gln, Arg194Trp, and Arg280His polymorphisms in esophageal cancer ris... | BeFree | 23543084 | Detail |
| <0.001 | Exanthema | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.013 | colorectal carcinoma | No association between the Arg194Trp and Arg399Gln polymorphisms of the XRCC1 ge... | BeFree | 18806752 | Detail |
| 0.098 | Malignant neoplasm of breast | The present study aimed to investigate the association between Arg194Trp (XRCC1)... | BeFree | 25862854 | Detail |
| 0.005 | diffuse large B-cell lymphoma | In addition, the XRCC1 Arg194Trp polymorphism was associated with decreased NHL ... | BeFree | 17666372 | Detail |
| 0.038 | Esophageal Neoplasms | XRCC1 Arg399Gln, Arg194Trp, and Arg280His polymorphisms in esophageal cancer ris... | BeFree | 23543084 | Detail |
| 0.012 | Non-small cell lung carcinoma | We used TaqMan to genotype four SNPs (APE1 Asp148Glu, PARP1 Va1762Ala, XRCC1 Arg... | BeFree | 23479135 | Detail |
| 0.018 | breast carcinoma | XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a ... | BeFree | 19465687 | Detail |
| 0.018 | breast carcinoma | Association of the Arg194Trp and the Arg399Gln polymorphisms of the XRCC1 gene w... | BeFree | 23103366 | Detail |
| 0.047 | Malignant neoplasm of prostate | This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms... | BeFree | 17196815 | Detail |
| <0.001 | breast fibrocystic disease | Variant alleles of XRCC1 Arg(194)Trp (rs1799782) and ERCC4 Arg(415)Gln (rs180006... | BeFree | 19124519 | Detail |
| 0.006 | Malignant neoplasm of mouth | Taken together, the genotypes of XRCC1 rs1799782 and XRCC2 rs2040639 DNA repair ... | BeFree | 25831063 | Detail |
| 0.011 | breast carcinoma | Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241... | BeFree | 25340946 | Detail |
| 0.028 | Malignant neoplasm of esophagus | Two non-synonymous polymorphisms Arg194Trp and Arg399Gln in the DNA-base excisio... | BeFree | 19444915 | Detail |
| <0.001 | Exanthema | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.006 | Neoplasm Metastasis | Results showed that Trp/Trp genotype of XRCC1 Arg194Trp and AA genotype of ERCC1... | BeFree | 25690281 | Detail |
| 0.003 | endometriosis | XRCC1 399 Arg-related genotype and allele, but not XRCC1 His107Arg, XRCC1 Trp194... | BeFree | 22084859 | Detail |
| <0.001 | Malignant tumor of cervix | XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associ... | BeFree | 18851872 | Detail |
| 0.005 | chronic lymphocytic leukemia | Investigation of Arg399Gln and Arg194Trp polymorphisms of the XRCC1 (x-ray cross... | BeFree | 22106831 | Detail |
| <0.001 | Spots on skin | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| <0.001 | Lip and oral cavity carcinoma | Taken together, the genotypes of XRCC1 rs1799782 and XRCC2 rs2040639 DNA repair ... | BeFree | 25831063 | Detail |
| 0.100 | Malignant neoplasm of lung | No association between XRCC1 gene Arg194Trp polymorphism and risk of lung cancer... | BeFree | 24590265 | Detail |
| <0.001 | Malignant neoplasm of nasopharynx | In addition, our work also points out the importance of new studies for Arg194Tr... | BeFree | 25064613 | Detail |
| <0.001 | Spots on skin | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| <0.001 | Exanthema | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.001 | Malignant neoplasm of thyroid | Our results suggest that the XRCC1 Arg399Gln polymorphism may be associated with... | BeFree | 23464463 | Detail |
| <0.001 | Exanthema | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.100 | Malignant neoplasm of lung | Contrasting impact of DNA repair gene XRCC1 polymorphisms Arg399Gln and Arg194Tr... | BeFree | 17417947 | Detail |
| 0.013 | colorectal carcinoma | No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal ca... | BeFree | 21612998 | Detail |
| <0.001 | Malignant neoplasm of mouth | Taken together, the genotypes of XRCC1 rs1799782 and XRCC2 rs2040639 DNA repair ... | BeFree | 25831063 | Detail |
| 0.006 | Malignant neoplasm of mouth | XRCC1 Arg194Trp polymorphism is associated with oral cancer risk: evidence from ... | BeFree | 23681796 | Detail |
| 0.001 | Spots on skin | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.018 | breast carcinoma | In addition, breast cancer risk was significantly associated with an increasing ... | BeFree | 14652281 | Detail |
| 0.098 | Malignant neoplasm of breast | XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a ... | BeFree | 19465687 | Detail |
| 0.005 | Leukemia, Lymphocytic, Acute, L1 | XRCC1 Arg399Gln and Arg194Trp polymorphisms in childhood acute lymphoblastic leu... | BeFree | 22712837 | Detail |
| 0.008 | Carcinoma of bladder | A meta-analysis on XRCC1 R399Q and R194W polymorphisms, smoking and bladder canc... | BeFree | 18765423 | Detail |
| 0.020 | Carcinoma of lung | Therefore, this meta-analysis suggests that XRCC1 Arg194Trp polymorphism is asso... | BeFree | 23653378 | Detail |
| 0.005 | Non-small cell lung carcinoma | The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280H... | BeFree | 11285194 | Detail |
| 0.003 | Thyroid Nodule | Elevated thyroid nodule risks were associated with the minor alleles of RET S836... | BeFree | 19138047 | Detail |
| 0.062 | colorectal cancer | The present meta-analysis suggests that the XRCC1 Arg194Trp polymorphism may mod... | BeFree | 23857281 | Detail |
| 0.062 | colorectal cancer | No association between the Arg194Trp and Arg399Gln polymorphisms of the XRCC1 ge... | BeFree | 18806752 | Detail |
| <0.001 | endometriosis | XRCC1 399 Arg-related genotype and allele, but not XRCC1 His107Arg, XRCC1 Trp194... | BeFree | 22084859 | Detail |
| 0.001 | Lip and oral cavity carcinoma | Taken together, the genotypes of XRCC1 rs1799782 and XRCC2 rs2040639 DNA repair ... | BeFree | 25831063 | Detail |
| 0.006 | Malignant neoplasm of prostate | This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms... | BeFree | 17196815 | Detail |
| 0.004 | Non-small cell lung carcinoma | We used TaqMan to genotype four SNPs (APE1 Asp148Glu, PARP1 Va1762Ala, XRCC1 Arg... | BeFree | 23479135 | Detail |
| 0.002 | differentiated thyroid gland carcinoma | Our meta-analysis suggests that XRCC1 Arg194Trp may be a risk factor for DTC dev... | BeFree | 24175846 | Detail |
| <0.001 | Spots on skin | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.018 | breast carcinoma | Meta-analyses based on our data and published data from studies of two single nu... | BeFree | 16492928 | Detail |
| 0.005 | Leukemia, Lymphocytic, Acute, L1 | We examined the influence of the Arg194Trp, Arg280His, and Arg399Gln polymorphis... | BeFree | 20013659 | Detail |
| 0.100 | Malignant neoplasm of lung | The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and b... | BeFree | 15840879 | Detail |
| 0.062 | colorectal cancer | No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal ca... | BeFree | 21612998 | Detail |
| 0.007 | Glioma | The XRCC1 Arg194Trp variant affects the proliferating cell nuclear antigen( PCNA... | BeFree | 25227852 | Detail |
| 0.003 | Malignant tumor of cervix | XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associ... | BeFree | 18851872 | Detail |
| 0.001 | Exanthema | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.003 | coronary artery disease | XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049)... | BeFree | 24315498 | Detail |
| 0.006 | Squamous cell carcinoma of the head and neck | In this study, two polymorphisms of the XRCC1 gene, Arg194Trp and Arg399Gln were... | BeFree | 15800678 | Detail |
| <0.001 | colon carcinoma | The present meta-analysis suggests that the XRCC1 Arg194Trp polymorphism may mod... | BeFree | 23857281 | Detail |
| 0.002 | pancreatic carcinoma | Lack of association of XRCC1 rs1799782 genetic polymorphism with risk of pancrea... | BeFree | 24435745 | Detail |
| <0.001 | Spots on skin | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.008 | Carcinoma of bladder | XRCC1 Arg194Trp and Arg280His polymorphisms increase bladder cancer risk in Asia... | BeFree | 23704969 | Detail |
| 0.079 | Malignant neoplasm of urinary bladder | A meta-analysis on XRCC1 R399Q and R194W polymorphisms, smoking and bladder canc... | BeFree | 18765423 | Detail |
| <0.001 | coronary artery disease | XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049)... | BeFree | 24315498 | Detail |
| 0.006 | Squamous cell carcinoma of the head and neck | The aim of this study was to investigate the association of XRCC1 Arg194Trp and ... | BeFree | 26011347 | Detail |
| <0.001 | Adenoma of large intestine | Using a large sigmoidoscopy-based case-control study (753 cases and 799 controls... | BeFree | 15767338 | Detail |
| 0.012 | Malignant neoplasm of pancreas | Yet only one polymorphism, XRCC1 Arg194Trp, appears to be involved in smoking-re... | BeFree | 17397816 | Detail |
| <0.001 | Exanthema | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.002 | prostate carcinoma | This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms... | BeFree | 17196815 | Detail |
| 0.079 | Malignant neoplasm of urinary bladder | XRCC1 Arg194Trp and Arg280His polymorphisms increase bladder cancer risk in Asia... | BeFree | 23704969 | Detail |
| 0.005 | Hodgkin Disease | We observed that, in combination, allelic variants in the XPC Ala499Val, NBN Glu... | BeFree | 21374732 | Detail |
| 0.079 | Malignant neoplasm of urinary bladder | XRCC1 Arg194Trp and Arg280His polymorphisms in bladder cancer susceptibility: a ... | BeFree | 24266849 | Detail |
| 0.013 | cervix carcinoma | XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associ... | BeFree | 18851872 | Detail |
| 0.013 | colorectal carcinoma | The present meta-analysis suggests that the XRCC1 Arg194Trp polymorphism may mod... | BeFree | 23857281 | Detail |
| 0.002 | pancreatic carcinoma | Yet only one polymorphism, XRCC1 Arg194Trp, appears to be involved in smoking-re... | BeFree | 17397816 | Detail |
| 0.003 | Hematologic Neoplasms | Study on the association between the Arg194Trp polymorphism in the XRCC1 gene an... | BeFree | 24414482 | Detail |
| 0.003 | cervix carcinoma | XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associ... | BeFree | 18851872 | Detail |
| 0.033 | adenocarcinoma | The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and b... | BeFree | 15840879 | Detail |
| 0.010 | Xeroderma Pigmentosum, Complementation Group D | Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RF... | BeFree | 20375340 | Detail |
| 0.002 | esophageal carcinoma | XRCC1 Arg399Gln, Arg194Trp, and Arg280His polymorphisms in esophageal cancer ris... | BeFree | 23543084 | Detail |
| 0.004 | Thyroid Nodule | Elevated thyroid nodule risks were associated with the minor alleles of RET S836... | BeFree | 19138047 | Detail |
| 0.001 | Lip and oral cavity carcinoma | We suggest that the Arg194Trp polymorphism in the XRCC1 gene may be a biomarker ... | BeFree | 19713684 | Detail |
| 0.012 | Malignant neoplasm of pancreas | Lack of association of XRCC1 rs1799782 genetic polymorphism with risk of pancrea... | BeFree | 24435745 | Detail |
| 0.020 | Carcinoma of lung | No association between XRCC1 gene Arg194Trp polymorphism and risk of lung cancer... | BeFree | 24590265 | Detail |
| 0.012 | Non-small cell lung carcinoma | Published data have shown conflicting results about the relationship between X-r... | BeFree | 22705987 | Detail |
| 0.100 | Malignant neoplasm of lung | Homozygous Trp/Trp variant genotype of XRCC1 Arg194Trp polymorphism could increa... | BeFree | 20975374 | Detail |
| 0.003 | Xeroderma Pigmentosum, Complementation Group D | The purpose of the study was to evaluate the association between XRCC1 Arg399Gln... | BeFree | 24955348 | Detail |
| 0.020 | Carcinoma of lung | Contrasting impact of DNA repair gene XRCC1 polymorphisms Arg399Gln and Arg194Tr... | BeFree | 17417947 | Detail |
| <0.001 | 5,10-Methylenetetrahydrofolate reductase deficiency | The present study aimed to investigate the association between Arg194Trp (XRCC1)... | BeFree | 25862854 | Detail |
| 0.098 | Malignant neoplasm of breast | Association of the Arg194Trp and the Arg399Gln polymorphisms of the XRCC1 gene w... | BeFree | 23103366 | Detail |
| 0.098 | Malignant neoplasm of breast | Meta-analyses based on our data and published data from studies of two single nu... | BeFree | 16492928 | Detail |
| 0.006 | Malignant neoplasm of mouth | We suggest that the Arg194Trp polymorphism in the XRCC1 gene may be a biomarker ... | BeFree | 19713684 | Detail |
| 0.008 | Chronic Obstructive Airway Disease | XRCC1 Arg194Trp polymorphism and risk of chronic obstructive pulmonary disease. | BeFree | 19821085 | Detail |
| 0.007 | prostate carcinoma | In conclusion, the meta-analysis suggests that there is no obvious association b... | BeFree | 24492938 | Detail |
| <0.001 | Squamous cell carcinoma of the head and neck | In addition, the interaction of CYP2E1 (CYP2E1*5B and CYP2E1*6) with other genet... | BeFree | 19334053 | Detail |
| 0.008 | endometriosis | XRCC1 399 Arg-related genotype and allele, but not XRCC1 His107Arg, XRCC1 Trp194... | BeFree | 22084859 | Detail |
| 0.018 | breast carcinoma | Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241... | BeFree | 25340946 | Detail |
| 0.021 | Glioma | Association between the XRCC1 Arg194Trp polymorphism and glioma risk: an updated... | BeFree | 25227852 | Detail |
| <0.001 | Spots on skin | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
| 0.006 | colorectal carcinoma | Using a family-based study, we investigated the role of polymorphisms in 4 BER g... | BeFree | 21037106 | Detail |
| 0.062 | colorectal cancer | Using a family-based study, we investigated the role of polymorphisms in 4 BER g... | BeFree | 21037106 | Detail |
| 0.013 | colorectal carcinoma | Using a family-based study, we investigated the role of polymorphisms in 4 BER g... | BeFree | 21037106 | Detail |
| 0.030 | colorectal cancer | Using a family-based study, we investigated the role of polymorphisms in 4 BER g... | BeFree | 21037106 | Detail |
| 0.007 | Malignant neoplasm of breast | rs1130409/T1865G (APEX1), rs1799782/T22142C (XRCC1), rs25487/G23990A (XRCC1), rs... | BeFree | 18669164 | Detail |
| 0.002 | breast carcinoma | rs1130409/T1865G (APEX1), rs1799782/T22142C (XRCC1), rs25487/G23990A (XRCC1), rs... | BeFree | 18669164 | Detail |
| 0.010 | colorectal carcinoma | In the present study, we investigated the role in colorectal cancer of single-nu... | BeFree | 18006925 | Detail |
| <0.001 | Hyperkeratosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.030 | colorectal cancer | In the present study, we investigated the role in colorectal cancer of single-nu... | BeFree | 18006925 | Detail |
| <0.001 | melanoma | We hypothesized that common nsSNPs of BER genes, specifically ADPRT rs1136410, X... | BeFree | 22687647 | Detail |
| 0.058 | colorectal cancer | In the present study, we investigated the role in colorectal cancer of single-nu... | BeFree | 18006925 | Detail |
| <0.001 | Melanosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.002 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| 0.010 | Glioma | No evidence of significant associations between ERCC2 rs1799793, OGG1 rs1052133,... | BeFree | 24500421 | Detail |
| 0.480 | Malignant neoplasm of breast | Nonetheless, published data were consistent with associations between: (a) the O... | BeFree | 12496039 | Detail |
| 0.007 | Carcinogenesis | However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg... | BeFree | 15840879 | Detail |
| <0.001 | Hyperkeratosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| <0.001 | Melanosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.098 | Malignant neoplasm of breast | Nonetheless, published data were consistent with associations between: (a) the O... | BeFree | 12496039 | Detail |
| <0.001 | Hyperkeratosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.006 | Leukoplakia | We examined the association of 13 variants in eight genes (rs4646903, rs2031920,... | BeFree | 21741876 | Detail |
| 0.156 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| 0.026 | Malignant neoplasm of breast | Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... | BeFree | 20183911 | Detail |
| <0.001 | keratosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.006 | colorectal carcinoma | In the present study, we investigated the role in colorectal cancer of single-nu... | BeFree | 18006925 | Detail |
| <0.001 | Melanosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.005 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| <0.001 | Rectal Carcinoma | We genotyped 1,181 controls and 311 cases (180 colon and 131 rectal cancer) for ... | BeFree | 20559012 | Detail |
| 0.004 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| 0.006 | stomach carcinoma | To evaluate the association between genetic polymorphisms of X-ray repair cross-... | BeFree | 19147860 | Detail |
| <0.001 | Melanosis coli | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.002 | Malignant neoplasm of stomach | To evaluate the association between genetic polymorphisms of X-ray repair cross-... | BeFree | 19147860 | Detail |
| 0.080 | breast carcinoma | Nonetheless, published data were consistent with associations between: (a) the O... | BeFree | 12496039 | Detail |
| <0.001 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| 0.072 | Malignant neoplasm of lung | Both the XRCC1 Arg194Trp and Arg280His as well as the OGG1 Ser326Cys heterozygou... | BeFree | 17531525 | Detail |
| 0.005 | breast carcinoma | Nonetheless, published data were consistent with associations between: (a) the O... | BeFree | 12496039 | Detail |
| 0.018 | breast carcinoma | Nonetheless, published data were consistent with associations between: (a) the O... | BeFree | 12496039 | Detail |
| <0.001 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| 0.002 | stomach carcinoma | To evaluate the association between genetic polymorphisms of X-ray repair cross-... | BeFree | 19147860 | Detail |
| 0.032 | Malignant neoplasm of breast | Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... | BeFree | 20183911 | Detail |
| 0.004 | breast carcinoma | Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... | BeFree | 20183911 | Detail |
| 0.098 | Malignant neoplasm of breast | Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... | BeFree | 20183911 | Detail |
| 0.002 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| <0.001 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| 0.001 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| <0.001 | keratosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.001 | Rectal Carcinoma | We genotyped 1,181 controls and 311 cases (180 colon and 131 rectal cancer) for ... | BeFree | 20559012 | Detail |
| 0.018 | breast carcinoma | Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... | BeFree | 20183911 | Detail |
| 0.018 | Malignant neoplasm of stomach | To evaluate the association between genetic polymorphisms of X-ray repair cross-... | BeFree | 19147860 | Detail |
| 0.006 | Carcinogenesis | However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg... | BeFree | 15840879 | Detail |
| 0.005 | breast carcinoma | Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys ... | BeFree | 20183911 | Detail |
| <0.001 | Melanosis coli | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.008 | stomach carcinoma | To evaluate the association between genetic polymorphisms of X-ray repair cross-... | BeFree | 19147860 | Detail |
| 0.013 | Carcinoma of lung | Both the XRCC1 Arg194Trp and Arg280His as well as the OGG1 Ser326Cys heterozygou... | BeFree | 17531525 | Detail |
| 0.012 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| 0.004 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| <0.001 | keratosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.013 | Malignant neoplasm of stomach | To evaluate the association between genetic polymorphisms of X-ray repair cross-... | BeFree | 19147860 | Detail |
| 0.006 | Leukoplakia | We examined the association of 13 variants in eight genes (rs4646903, rs2031920,... | BeFree | 21741876 | Detail |
| <0.001 | Melanosis coli | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| 0.026 | Malignant neoplasm of breast | Nonetheless, published data were consistent with associations between: (a) the O... | BeFree | 12496039 | Detail |
| 0.004 | Non-small cell lung carcinoma | We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs2548... | BeFree | 21420246 | Detail |
| 0.019 | Malignant neoplasm of breast | The results indicate that the polymorphisms rs1130409 (APEX1) and rs25487 (XRCC1... | BeFree | 18669164 | Detail |
| <0.001 | Rash and Dermatitis Adverse Event Associated with Chemoradiation | We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs2548... | BeFree | 21420246 | Detail |
| <0.001 | Rash and Dermatitis Adverse Event Associated with Chemoradiation | We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs2548... | BeFree | 21420246 | Detail |
| <0.001 | Rash and Dermatitis Adverse Event Associated with Chemoradiation | We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs2548... | BeFree | 21420246 | Detail |
| 0.005 | breast carcinoma | The results indicate that the polymorphisms rs1130409 (APEX1) and rs25487 (XRCC1... | BeFree | 18669164 | Detail |
| 0.098 | Malignant neoplasm of breast | The results indicate that the polymorphisms rs1130409 (APEX1) and rs25487 (XRCC1... | BeFree | 18669164 | Detail |
| 0.018 | breast carcinoma | The results indicate that the polymorphisms rs1130409 (APEX1) and rs25487 (XRCC1... | BeFree | 18669164 | Detail |
| 0.002 | Nasopharyngeal carcinoma | The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... | BeFree | 25481674 | Detail |
| 0.003 | Nasopharyngeal carcinoma | The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... | BeFree | 25481674 | Detail |
| <0.001 | Small cell carcinoma of esophagus | We retrospectively examined whether there was an association between the selecte... | BeFree | 25374063 | Detail |
| <0.001 | Small cell carcinoma of esophagus | We retrospectively examined whether there was an association between the selecte... | BeFree | 25374063 | Detail |
| 0.003 | stomach carcinoma | ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in ... | BeFree | 22901183 | Detail |
| <0.001 | Small cell carcinoma of esophagus | We retrospectively examined whether there was an association between the selecte... | BeFree | 25374063 | Detail |
| <0.001 | Small cell carcinoma of esophagus | We retrospectively examined whether there was an association between the selecte... | BeFree | 25374063 | Detail |
| 0.008 | stomach carcinoma | ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in ... | BeFree | 22901183 | Detail |
| <0.001 | Small cell carcinoma of esophagus | We retrospectively examined whether there was an association between the selecte... | BeFree | 25374063 | Detail |
| 0.003 | Malignant neoplasm of stomach | ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in ... | BeFree | 22901183 | Detail |
| 0.018 | Malignant neoplasm of stomach | ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in ... | BeFree | 22901183 | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| The XRCC1 R194W variant was shown to be correlated with increased chance of response to platinum-bas... | CIViC Evidence | Detail |
| NM_006297.3(XRCC1):c.580C>T (p.Arg194Trp) AND Non-small cell lung carcinoma | ClinVar | Detail |
| NM_006297.3(XRCC1):c.580C>T (p.Arg194Trp) AND not provided | ClinVar | Detail |
| The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... | DisGeNET | Detail |
| The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... | DisGeNET | Detail |
| The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... | DisGeNET | Detail |
| The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R415Q (rs1800067), MSH3... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R415Q (rs1800067), MSH3... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R415Q (rs1800067), MSH3... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R415Q (rs1800067), MSH3... | DisGeNET | Detail |
| Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing c... | DisGeNET | Detail |
| Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R415Q (rs1800067), MSH3... | DisGeNET | Detail |
| Our results suggest that TNBC was associated with 6 DNA-repair nsSNPs, ERCC4 R415Q (rs1800067), MSH3... | DisGeNET | Detail |
| Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among ... | DisGeNET | Detail |
| Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among ... | DisGeNET | Detail |
| Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair genes were investigated:... | DisGeNET | Detail |
| Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and Arg194Trp): relations... | DisGeNET | Detail |
| Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among ... | DisGeNET | Detail |
| Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among ... | DisGeNET | Detail |
| Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair genes were investigated:... | DisGeNET | Detail |
| Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793), XRCC1 Arg194Trp (rs1799782)... | DisGeNET | Detail |
| Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among ... | DisGeNET | Detail |
| Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among ... | DisGeNET | Detail |
| Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and Arg194Trp): relations... | DisGeNET | Detail |
| Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair genes were investigated:... | DisGeNET | Detail |
| Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and Arg194Trp): relations... | DisGeNET | Detail |
| Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and Arg194Trp): relations... | DisGeNET | Detail |
| Nine known single nucleotide polymorphisms (SNPs) in five common DNA repair genes were investigated:... | DisGeNET | Detail |
| Genetic variants ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793), XRCC1 Arg194Trp (rs1799782)... | DisGeNET | Detail |
| Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among ... | DisGeNET | Detail |
| Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among ... | DisGeNET | Detail |
| Our comprehensive analysis of nine SNPs in eight genes suggests that the rs730437 and rs1468727 in E... | DisGeNET | Detail |
| Our comprehensive analysis of nine SNPs in eight genes suggests that the rs730437 and rs1468727 in E... | DisGeNET | Detail |
| The germline polymorphisms studied were thymidylate synthase, (VNTR/5'UTR, 2R G>C single nucleoti... | DisGeNET | Detail |
| The germline polymorphisms studied were thymidylate synthase, (VNTR/5'UTR, 2R G>C single nucleoti... | DisGeNET | Detail |
| The germline polymorphisms studied were thymidylate synthase, (VNTR/5'UTR, 2R G>C single nucleoti... | DisGeNET | Detail |
| The germline polymorphisms studied were thymidylate synthase, (VNTR/5'UTR, 2R G>C single nucleoti... | DisGeNET | Detail |
| In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... | DisGeNET | Detail |
| In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... | DisGeNET | Detail |
| In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... | DisGeNET | Detail |
| In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... | DisGeNET | Detail |
| In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... | DisGeNET | Detail |
| In conclusion, our study has shown that XRCC1 Gln399Arg, XRCC1 Arg194Trp, XRCC3 Thr241Met and ERCC5 ... | DisGeNET | Detail |
| The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280His and Arg399Gln), X... | DisGeNET | Detail |
| The purpose of the study was to evaluate the association between XRCC1 Arg399Gln, Arg280His and Arg1... | DisGeNET | Detail |
| XRCC1 genetic polymorphism Arg339Gln, Arg194Trp, Arg280His and gastric cancer risk: an evidence base... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and between XRCC1 Arg194T... | DisGeNET | Detail |
| This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms in PC, and our pres... | DisGeNET | Detail |
| To investigate the effect of XPD Lys751Gln, XRCC1 Arg399Gln, Arg194Trp, Arg280His, and XRCC3 Thr241M... | DisGeNET | Detail |
| The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280His and Arg399Gln), X... | DisGeNET | Detail |
| XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are associated with uro... | DisGeNET | Detail |
| Decreased glioma risk was observed with the XRCC1 rs1799782 variant (P(trend) .04). | DisGeNET | Detail |
| The XRCC1 Arg194Trp and Arg280His polymorphisms in head and neck cancer susceptibility: a meta-analy... | DisGeNET | Detail |
| Similarly, the pseudo-haplotype of rs2040639-rs861539-rs2075685 (XRCC2-XRCC3-XRCC4) and rs2040639-rs... | DisGeNET | Detail |
| In conclusion, the result from our study provides additional evidence of an association of the XRCC1... | DisGeNET | Detail |
| The present meta-analysis suggests that the XRCC1 Arg194Trp polymorphism may modify the risk for CRC... | DisGeNET | Detail |
| Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms w... | DisGeNET | Detail |
| Results showed that Trp/Trp genotype of XRCC1 Arg194Trp and AA genotype of ERCC1 rs2336219 have a si... | DisGeNET | Detail |
| The purpose of this study was to examine the association of two genetic polymorphisms in XRCC1 (rs17... | DisGeNET | Detail |
| Two non-synonymous polymorphisms Arg194Trp and Arg399Gln in the DNA-base excision repair gene X-ray ... | DisGeNET | Detail |
| The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and between XRCC1 Arg194T... | DisGeNET | Detail |
| The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and between XRCC1 Arg194T... | DisGeNET | Detail |
| XRCC1 genetic polymorphism Arg339Gln, Arg194Trp, Arg280His and gastric cancer risk: an evidence base... | DisGeNET | Detail |
| In addition, our work also points out the importance of new studies for Arg194Trp association in som... | DisGeNET | Detail |
| XRCC1 Arg399Gln and Arg194Trp polymorphisms and risk of systemic lupus erythematosus in an Iranian p... | DisGeNET | Detail |
| Similarly, the pseudo-haplotype of rs2040639-rs861539-rs2075685 (XRCC2-XRCC3-XRCC4) and rs2040639-rs... | DisGeNET | Detail |
| Two non-synonymous polymorphisms Arg194Trp and Arg399Gln in the DNA-base excision repair gene X-ray ... | DisGeNET | Detail |
| In addition, breast cancer risk was significantly associated with an increasing number of combined v... | DisGeNET | Detail |
| To evaluate contribution of single nucleotide polymorphisms (SNPs) of X-ray repair cross-complementi... | DisGeNET | Detail |
| We genotyped five non-synonymous single-nucleotide polymorphisms of three genes, including the human... | DisGeNET | Detail |
| XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are associated with uro... | DisGeNET | Detail |
| XRCC1 Arg399Gln and Arg194Trp polymorphisms in prostate cancer risk: a meta-analysis. | DisGeNET | Detail |
| XRCC1 Arg399Gln and Arg194Trp polymorphisms in prostate cancer risk: a meta-analysis. | DisGeNET | Detail |
| Homozygous Trp/Trp variant genotype of XRCC1 Arg194Trp polymorphism could increase lung cancer risk ... | DisGeNET | Detail |
| XRCC1 Arg194Trp and Arg280His polymorphisms in bladder cancer susceptibility: a meta-analysis. | DisGeNET | Detail |
| Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms w... | DisGeNET | Detail |
| In addition, our work also points out the importance of new studies for Arg194Trp association in som... | DisGeNET | Detail |
| XRCC1 Arg194Trp polymorphism is associated with oral cancer risk: evidence from a meta-analysis. | DisGeNET | Detail |
| In conclusion, the meta-analysis suggests that there is no obvious association between XRCC1 Arg194T... | DisGeNET | Detail |
| The present study aimed to investigate the association between Arg194Trp (XRCC1), Ala222Val (MTHFR) ... | DisGeNET | Detail |
| Therefore, this meta-analysis suggests that XRCC1 Arg194Trp polymorphism is associated with increase... | DisGeNET | Detail |
| Our study showed that the polymorphic status of XRCC1 194Arg/Trp might be a predictive marker of tre... | DisGeNET | Detail |
| Our findings demonstrated that the genetic variant Arg280His in XRCC1 may contribute to cancer progr... | DisGeNET | Detail |
| XRCC1 Arg194Trp and Arg399Gln polymorphisms are significantly associated with shorter survival in ac... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and between XRCC1 Arg194T... | DisGeNET | Detail |
| XRCC1 Arg399Gln, Arg194Trp, and Arg280His polymorphisms in esophageal cancer risk: a meta-analysis. | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| No association between the Arg194Trp and Arg399Gln polymorphisms of the XRCC1 gene and colorectal ca... | DisGeNET | Detail |
| The present study aimed to investigate the association between Arg194Trp (XRCC1), Ala222Val (MTHFR) ... | DisGeNET | Detail |
| In addition, the XRCC1 Arg194Trp polymorphism was associated with decreased NHL risk (Arg/Trp vs. Ar... | DisGeNET | Detail |
| XRCC1 Arg399Gln, Arg194Trp, and Arg280His polymorphisms in esophageal cancer risk: a meta-analysis. | DisGeNET | Detail |
| We used TaqMan to genotype four SNPs (APE1 Asp148Glu, PARP1 Va1762Ala, XRCC1 Arg194Trp and XRCC1 Arg... | DisGeNET | Detail |
| XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a meta-analysis. | DisGeNET | Detail |
| Association of the Arg194Trp and the Arg399Gln polymorphisms of the XRCC1 gene with risk occurrence ... | DisGeNET | Detail |
| This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms in PC, and our pres... | DisGeNET | Detail |
| Variant alleles of XRCC1 Arg(194)Trp (rs1799782) and ERCC4 Arg(415)Gln (rs1800067) were significantl... | DisGeNET | Detail |
| Taken together, the genotypes of XRCC1 rs1799782 and XRCC2 rs2040639 DNA repair genes appear to be s... | DisGeNET | Detail |
| Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms w... | DisGeNET | Detail |
| Two non-synonymous polymorphisms Arg194Trp and Arg399Gln in the DNA-base excision repair gene X-ray ... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| Results showed that Trp/Trp genotype of XRCC1 Arg194Trp and AA genotype of ERCC1 rs2336219 have a si... | DisGeNET | Detail |
| XRCC1 399 Arg-related genotype and allele, but not XRCC1 His107Arg, XRCC1 Trp194Arg, KCNQ2, AT1R, an... | DisGeNET | Detail |
| XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associated with response t... | DisGeNET | Detail |
| Investigation of Arg399Gln and Arg194Trp polymorphisms of the XRCC1 (x-ray cross-complementing group... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| Taken together, the genotypes of XRCC1 rs1799782 and XRCC2 rs2040639 DNA repair genes appear to be s... | DisGeNET | Detail |
| No association between XRCC1 gene Arg194Trp polymorphism and risk of lung cancer: evidence based on ... | DisGeNET | Detail |
| In addition, our work also points out the importance of new studies for Arg194Trp association in som... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| Our results suggest that the XRCC1 Arg399Gln polymorphism may be associated with decreased thyroid c... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| Contrasting impact of DNA repair gene XRCC1 polymorphisms Arg399Gln and Arg194Trp on the risk of lun... | DisGeNET | Detail |
| No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal cancer risk. | DisGeNET | Detail |
| Taken together, the genotypes of XRCC1 rs1799782 and XRCC2 rs2040639 DNA repair genes appear to be s... | DisGeNET | Detail |
| XRCC1 Arg194Trp polymorphism is associated with oral cancer risk: evidence from a meta-analysis. | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| In addition, breast cancer risk was significantly associated with an increasing number of combined v... | DisGeNET | Detail |
| XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a meta-analysis. | DisGeNET | Detail |
| XRCC1 Arg399Gln and Arg194Trp polymorphisms in childhood acute lymphoblastic leukemia risk: a meta-a... | DisGeNET | Detail |
| A meta-analysis on XRCC1 R399Q and R194W polymorphisms, smoking and bladder cancer risk. | DisGeNET | Detail |
| Therefore, this meta-analysis suggests that XRCC1 Arg194Trp polymorphism is associated with increase... | DisGeNET | Detail |
| The frequencies of several amino acid substitutions in XRCC1 (Arg194Trp, Arg280His and Arg399Gln), X... | DisGeNET | Detail |
| Elevated thyroid nodule risks were associated with the minor alleles of RET S836S (rs1800862, P = 0.... | DisGeNET | Detail |
| The present meta-analysis suggests that the XRCC1 Arg194Trp polymorphism may modify the risk for CRC... | DisGeNET | Detail |
| No association between the Arg194Trp and Arg399Gln polymorphisms of the XRCC1 gene and colorectal ca... | DisGeNET | Detail |
| XRCC1 399 Arg-related genotype and allele, but not XRCC1 His107Arg, XRCC1 Trp194Arg, KCNQ2, AT1R, an... | DisGeNET | Detail |
| Taken together, the genotypes of XRCC1 rs1799782 and XRCC2 rs2040639 DNA repair genes appear to be s... | DisGeNET | Detail |
| This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms in PC, and our pres... | DisGeNET | Detail |
| We used TaqMan to genotype four SNPs (APE1 Asp148Glu, PARP1 Va1762Ala, XRCC1 Arg194Trp and XRCC1 Arg... | DisGeNET | Detail |
| Our meta-analysis suggests that XRCC1 Arg194Trp may be a risk factor for DTC development. | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| Meta-analyses based on our data and published data from studies of two single nucleotide polymorphis... | DisGeNET | Detail |
| We examined the influence of the Arg194Trp, Arg280His, and Arg399Gln polymorphisms of XRCC1 (X-ray r... | DisGeNET | Detail |
| The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and between XRCC1 Arg194T... | DisGeNET | Detail |
| No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal cancer risk. | DisGeNET | Detail |
| The XRCC1 Arg194Trp variant affects the proliferating cell nuclear antigen( PCNA) binding region, wh... | DisGeNET | Detail |
| XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associated with response t... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049), and NQO1 (rs180056... | DisGeNET | Detail |
| In this study, two polymorphisms of the XRCC1 gene, Arg194Trp and Arg399Gln were investigated in 95 ... | DisGeNET | Detail |
| The present meta-analysis suggests that the XRCC1 Arg194Trp polymorphism may modify the risk for CRC... | DisGeNET | Detail |
| Lack of association of XRCC1 rs1799782 genetic polymorphism with risk of pancreatic cancer: a meta-a... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| XRCC1 Arg194Trp and Arg280His polymorphisms increase bladder cancer risk in Asian population: eviden... | DisGeNET | Detail |
| A meta-analysis on XRCC1 R399Q and R194W polymorphisms, smoking and bladder cancer risk. | DisGeNET | Detail |
| XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049), and NQO1 (rs180056... | DisGeNET | Detail |
| The aim of this study was to investigate the association of XRCC1 Arg194Trp and Arg399Gln single nuc... | DisGeNET | Detail |
| Using a large sigmoidoscopy-based case-control study (753 cases and 799 controls) in Los Angeles Cou... | DisGeNET | Detail |
| Yet only one polymorphism, XRCC1 Arg194Trp, appears to be involved in smoking-related cancers and in... | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| This is the first report on the studies of XPC and XRCC1 Arg194Trp polymorphisms in PC, and our pres... | DisGeNET | Detail |
| XRCC1 Arg194Trp and Arg280His polymorphisms increase bladder cancer risk in Asian population: eviden... | DisGeNET | Detail |
| We observed that, in combination, allelic variants in the XPC Ala499Val, NBN Glu185Gln, XRCC3 Thr241... | DisGeNET | Detail |
| XRCC1 Arg194Trp and Arg280His polymorphisms in bladder cancer susceptibility: a meta-analysis. | DisGeNET | Detail |
| XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associated with response t... | DisGeNET | Detail |
| The present meta-analysis suggests that the XRCC1 Arg194Trp polymorphism may modify the risk for CRC... | DisGeNET | Detail |
| Yet only one polymorphism, XRCC1 Arg194Trp, appears to be involved in smoking-related cancers and in... | DisGeNET | Detail |
| Study on the association between the Arg194Trp polymorphism in the XRCC1 gene and the risk of hemato... | DisGeNET | Detail |
| XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associated with response t... | DisGeNET | Detail |
| The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and between XRCC1 Arg194T... | DisGeNET | Detail |
| Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) were used to ana... | DisGeNET | Detail |
| XRCC1 Arg399Gln, Arg194Trp, and Arg280His polymorphisms in esophageal cancer risk: a meta-analysis. | DisGeNET | Detail |
| Elevated thyroid nodule risks were associated with the minor alleles of RET S836S (rs1800862, P = 0.... | DisGeNET | Detail |
| We suggest that the Arg194Trp polymorphism in the XRCC1 gene may be a biomarker of oral cancer susce... | DisGeNET | Detail |
| Lack of association of XRCC1 rs1799782 genetic polymorphism with risk of pancreatic cancer: a meta-a... | DisGeNET | Detail |
| No association between XRCC1 gene Arg194Trp polymorphism and risk of lung cancer: evidence based on ... | DisGeNET | Detail |
| Published data have shown conflicting results about the relationship between X-ray repair cross-comp... | DisGeNET | Detail |
| Homozygous Trp/Trp variant genotype of XRCC1 Arg194Trp polymorphism could increase lung cancer risk ... | DisGeNET | Detail |
| The purpose of the study was to evaluate the association between XRCC1 Arg399Gln, Arg280His and Arg1... | DisGeNET | Detail |
| Contrasting impact of DNA repair gene XRCC1 polymorphisms Arg399Gln and Arg194Trp on the risk of lun... | DisGeNET | Detail |
| The present study aimed to investigate the association between Arg194Trp (XRCC1), Ala222Val (MTHFR) ... | DisGeNET | Detail |
| Association of the Arg194Trp and the Arg399Gln polymorphisms of the XRCC1 gene with risk occurrence ... | DisGeNET | Detail |
| Meta-analyses based on our data and published data from studies of two single nucleotide polymorphis... | DisGeNET | Detail |
| We suggest that the Arg194Trp polymorphism in the XRCC1 gene may be a biomarker of oral cancer susce... | DisGeNET | Detail |
| XRCC1 Arg194Trp polymorphism and risk of chronic obstructive pulmonary disease. | DisGeNET | Detail |
| In conclusion, the meta-analysis suggests that there is no obvious association between XRCC1 Arg194T... | DisGeNET | Detail |
| In addition, the interaction of CYP2E1 (CYP2E1*5B and CYP2E1*6) with other genetic factors (null gen... | DisGeNET | Detail |
| XRCC1 399 Arg-related genotype and allele, but not XRCC1 His107Arg, XRCC1 Trp194Arg, KCNQ2, AT1R, an... | DisGeNET | Detail |
| Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms w... | DisGeNET | Detail |
| Association between the XRCC1 Arg194Trp polymorphism and glioma risk: an updated meta-analysis. | DisGeNET | Detail |
| Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
| Using a family-based study, we investigated the role of polymorphisms in 4 BER genes (APEX1 Gln51His... | DisGeNET | Detail |
| Using a family-based study, we investigated the role of polymorphisms in 4 BER genes (APEX1 Gln51His... | DisGeNET | Detail |
| Using a family-based study, we investigated the role of polymorphisms in 4 BER genes (APEX1 Gln51His... | DisGeNET | Detail |
| Using a family-based study, we investigated the role of polymorphisms in 4 BER genes (APEX1 Gln51His... | DisGeNET | Detail |
| rs1130409/T1865G (APEX1), rs1799782/T22142C (XRCC1), rs25487/G23990A (XRCC1), rs4989588/T3337A (FEN1... | DisGeNET | Detail |
| rs1130409/T1865G (APEX1), rs1799782/T22142C (XRCC1), rs25487/G23990A (XRCC1), rs4989588/T3337A (FEN1... | DisGeNET | Detail |
| In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... | DisGeNET | Detail |
| We hypothesized that common nsSNPs of BER genes, specifically ADPRT rs1136410, XRCC1 rs25487, rs2548... | DisGeNET | Detail |
| In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| No evidence of significant associations between ERCC2 rs1799793, OGG1 rs1052133, XRCC1 rs25489, XRCC... | DisGeNET | Detail |
| Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... | DisGeNET | Detail |
| However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg194Trp polymorphisms... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| We examined the association of 13 variants in eight genes (rs4646903, rs2031920, rs3813867, GSTM1 nu... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| In the present study, we investigated the role in colorectal cancer of single-nucleotide polymorphis... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| We genotyped 1,181 controls and 311 cases (180 colon and 131 rectal cancer) for SNPs in the XRCC1 (A... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... | DisGeNET | Detail |
| Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| Both the XRCC1 Arg194Trp and Arg280His as well as the OGG1 Ser326Cys heterozygous genotypes were ass... | DisGeNET | Detail |
| Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... | DisGeNET | Detail |
| Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... | DisGeNET | Detail |
| Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... | DisGeNET | Detail |
| Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... | DisGeNET | Detail |
| Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| We genotyped 1,181 controls and 311 cases (180 colon and 131 rectal cancer) for SNPs in the XRCC1 (A... | DisGeNET | Detail |
| Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... | DisGeNET | Detail |
| To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... | DisGeNET | Detail |
| However, we cannot exclude the possibility that the OGG1 Ser326Cys and XRCC1 Arg194Trp polymorphisms... | DisGeNET | Detail |
| Genotyping of polymorphisms of XRCC1 (Arg194Trp and Arg399Gln), OGG1 (Ser326Cys and Arg229Gln), ERCC... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... | DisGeNET | Detail |
| Both the XRCC1 Arg194Trp and Arg280His as well as the OGG1 Ser326Cys heterozygous genotypes were ass... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... | DisGeNET | Detail |
| We examined the association of 13 variants in eight genes (rs4646903, rs2031920, rs3813867, GSTM1 nu... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| Nonetheless, published data were consistent with associations between: (a) the OGG1 S326C variant an... | DisGeNET | Detail |
| We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs25489 [R280H], and rs254... | DisGeNET | Detail |
| The results indicate that the polymorphisms rs1130409 (APEX1) and rs25487 (XRCC1) might be involved ... | DisGeNET | Detail |
| We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs25489 [R280H], and rs254... | DisGeNET | Detail |
| We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs25489 [R280H], and rs254... | DisGeNET | Detail |
| We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs25489 [R280H], and rs254... | DisGeNET | Detail |
| The results indicate that the polymorphisms rs1130409 (APEX1) and rs25487 (XRCC1) might be involved ... | DisGeNET | Detail |
| The results indicate that the polymorphisms rs1130409 (APEX1) and rs25487 (XRCC1) might be involved ... | DisGeNET | Detail |
| The results indicate that the polymorphisms rs1130409 (APEX1) and rs25487 (XRCC1) might be involved ... | DisGeNET | Detail |
| The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... | DisGeNET | Detail |
| The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... | DisGeNET | Detail |
| We retrospectively examined whether there was an association between the selected six single nucleot... | DisGeNET | Detail |
| We retrospectively examined whether there was an association between the selected six single nucleot... | DisGeNET | Detail |
| ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China. | DisGeNET | Detail |
| We retrospectively examined whether there was an association between the selected six single nucleot... | DisGeNET | Detail |
| We retrospectively examined whether there was an association between the selected six single nucleot... | DisGeNET | Detail |
| ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China. | DisGeNET | Detail |
| We retrospectively examined whether there was an association between the selected six single nucleot... | DisGeNET | Detail |
| ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China. | DisGeNET | Detail |
| ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China. | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs1799782 dbSNP
- Genome
- hg38
- Position
- chr19:43,553,422-43,553,422
- Variant Type
- snv
- Reference Allele
- G
- Alternative Allele
- A
- Filtering Status (HGVD)
- PASS
- # of samples (HGVD)
- 1208
- Mean of sample read depth (HGVD)
- 84.28
- Standard deviation of sample read depth (HGVD)
- 38.71
- Number of reference allele (HGVD)
- 1660
- Number of alternative allele (HGVD)
- 756
- Allele Frequency (HGVD)
- 0.3129139072847682
- Gene Symbol (HGVD)
- XRCC1
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs1799782
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.3121
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 5231
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16760
- East Asian Chromosome Counts (ExAC)
- 8628
- East Asian Allele Counts (ExAC)
- 2652
- East Asian Heterozygous Counts (ExAC)
- 1880
- East Asian Homozygous Counts (ExAC)
- 386
- East Asian Allele Frequency (ExAC)
- 0.30737134909596664
- Chromosome Counts in All Race (ExAC)
- 121306
- Allele Counts in All Race (ExAC)
- 11252
- Heterozygous Counts in All Race (ExAC)
- 9642
- Homozygous Counts in All Race (ExAC)
- 805
- Allele Frequency in All Race (ExAC)
- 0.09275715957990537
- Variant (CIViC) (CIViC Variant)
- R194W
- Transcript 1 (CIViC Variant)
- ENST00000262887.5
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/249
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