chr3:12351626:C>G Detail (hg38) (PPARG)

Information

Genome

Assembly Position
hg19 chr3:12,393,125-12,393,125 View the variant detail on this assembly version.
hg38 chr3:12,351,626-12,351,626

HGVS

Type Transcript Protein
RefSeq NM_015869.4:c.34C>G NP_056953.2:p.Pro12Ala
NM_138712.3:c.-8-28078C>G
NM_005037.5:c.-8-28078C>G
Summary

MGeND

Clinical significance Benign
Variant entry 1
GWAS entry
Disease area statistics Show details

Frequency

JP HGVD:0.028
ToMMo:0.030
NCBN:[No Data.]
NCBN(Hondo):[No Data.]
NCBN(Ryukyu):[No Data.]
East asia ExAC:0.043

Prediction

ClinVar

Clinical Significance Benign Likely benign
Review star
Show details
Links
Type Database ID Link
Gene MIM 601487 OMIM
HGNC 9236 HGNC
Ensembl ENSG00000132170 Ensembl
NCBI NCBI
Gene Cards Gene Cards
OncoKB OncoKB
Type Database ID Link
Variant TogoVar tgv11497421 TogoVar
COSMIC
MONDO
Disease area statistics
MGeND
Clinical significance Last evaluated Condition Origin Submission ID Submitter Institute Citation Comment Image
Benign Centenarian germline MGS000068
(TMGS000140)
Kenjiro Kosaki Keio University
ClinVar
Clinical significance Last evaluated Review status Condition Origin Links
Likely benign no assertion criteria provided not specified germline Detail
Likely benign 2017-04-27 criteria provided, single submitter Diabetes Mellitus, Noninsulin-Dependent, with Acanthosis Nigricans and Hypertension germline Detail
Likely benign 2017-04-27 criteria provided, single submitter PPARG-related familial partial lipodystrophy germline Detail
Likely benign 2017-04-27 criteria provided, single submitter obesity germline Detail
Benign 2024-01-31 criteria provided, multiple submitters, no conflicts not provided germline Detail
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.439 obesity Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP... BeFree 15972940 Detail
0.641 obesity Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP... BeFree 15972940 Detail
0.002 obesity Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP... BeFree 15972940 Detail
0.329 Diabetes Mellitus, Non-Insulin-Dependent In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... BeFree 18498634 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... BeFree 18498634 Detail
0.614 Diabetes Mellitus, Non-Insulin-Dependent In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... BeFree 18498634 Detail
0.330 Diabetes Mellitus, Non-Insulin-Dependent In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... BeFree 18498634 Detail
0.340 Diabetes Mellitus, Non-Insulin-Dependent In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... BeFree 18498634 Detail
0.322 Diabetes Mellitus, Non-Insulin-Dependent In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... BeFree 18498634 Detail
0.440 obesity Seven variants displaying conflicting results in previous reports and supposedly... BeFree 21233811 Detail
0.439 obesity Seven variants displaying conflicting results in previous reports and supposedly... BeFree 21233811 Detail
0.147 obesity Seven variants displaying conflicting results in previous reports and supposedly... BeFree 21233811 Detail
0.034 obesity Seven variants displaying conflicting results in previous reports and supposedly... BeFree 21233811 Detail
0.002 colorectal carcinoma The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs18... BeFree 24552298 Detail
0.039 colorectal cancer The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs18... BeFree 24552298 Detail
0.016 colorectal cancer The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs18... BeFree 24552298 Detail
0.011 colorectal carcinoma The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs18... BeFree 24552298 Detail
<0.001 Fibrosis, Liver The variables significantly associated with SVR in a multivariate analysis were ... BeFree 25072612 Detail
0.008 Fibrosis, Liver The variables significantly associated with SVR in a multivariate analysis were ... BeFree 25072612 Detail
0.002 Fibrosis, Liver The variables significantly associated with SVR in a multivariate analysis were ... BeFree 25072612 Detail
0.004 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
0.003 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 Malignant neoplasm of pancreas We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
<0.001 pancreatic carcinoma We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADI... BeFree 25516658 Detail
0.154 Diabetes Mellitus, Non-Insulin-Dependent The PPAR-γ2 gene rs1801282 polymorphism was significantly associated with type 2... BeFree 23147557 Detail
0.125 Diabetes Mellitus, Non-Insulin-Dependent The PPAR-γ2 gene rs1801282 polymorphism was significantly associated with type 2... BeFree 23147557 Detail
0.004 Diabetes Mellitus, Non-Insulin-Dependent The PPAR-γ2 gene rs1801282 polymorphism was significantly associated with type 2... BeFree 23147557 Detail
0.003 diabetes mellitus Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associat... BeFree 23147557 Detail
0.008 Diabetes Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associat... BeFree 23147557 Detail
0.016 diabetes mellitus Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associat... BeFree 23147557 Detail
<0.001 Diabetes Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associat... BeFree 23147557 Detail
0.039 colorectal cancer We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), ... BeFree 16937502 Detail
0.007 colorectal carcinoma We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), ... BeFree 16937502 Detail
0.037 colorectal cancer We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), ... BeFree 16937502 Detail
0.011 colorectal carcinoma We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), ... BeFree 16937502 Detail
0.026 colorectal cancer We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), ... BeFree 16937502 Detail
0.011 colorectal carcinoma We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), ... BeFree 16937502 Detail
0.001 Metabolic syndrome X The frequency distribution of rare alleles for PPARα (L162V) and PPARγ (P12A and... BeFree 21877956 Detail
0.003 Non-alcoholic Fatty Liver Disease The objective of this study was to analyze the polymorphisms Leu162Val of PPARα ... BeFree 23891824 Detail
0.007 HIV Infections The frequency distribution of rare alleles for PPARα (L162V) and PPARγ (P12A and... BeFree 21877956 Detail
0.124 Non-alcoholic Fatty Liver Disease The objective of this study was to analyze the polymorphisms Leu162Val of PPARα ... BeFree 23891824 Detail
0.003 multiple sclerosis We investigated the association of two common single nucleotide polymorphisms in... BeFree 18977277 Detail
0.163 diabetes mellitus Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala... BeFree 10757637 Detail
0.439 obesity The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabe... BeFree 10757637 Detail
0.008 Diabetes Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala... BeFree 10757637 Detail
0.017 Diabetes The association of the Pro12Ala and Pro115Gln PPARgamma2 gene variants with type... BeFree 11079814 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabe... BeFree 10757637 Detail
0.017 Diabetes Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala... BeFree 10757637 Detail
0.163 diabetes mellitus The association of the Pro12Ala and Pro115Gln PPARgamma2 gene variants with type... BeFree 11079814 Detail
0.016 diabetes mellitus Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala... BeFree 10757637 Detail
0.466 Diabetes Mellitus, Non-Insulin-Dependent We have genotyped three single nucleotide polymorphisms associated with type 2 d... BeFree 14988278 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent By using a Cox proportional hazard model, common variants in the PPARG (P12A), C... BeFree 17570749 Detail
0.401 Diabetes Mellitus, Non-Insulin-Dependent The peroxisome proliferator-activated receptor gamma (PPARG), Pro12Ala and the i... BeFree 24447396 Detail
0.274 Diabetes Mellitus, Non-Insulin-Dependent By using a Cox proportional hazard model, common variants in the PPARG (P12A), C... BeFree 17570749 Detail
0.466 Diabetes Mellitus, Non-Insulin-Dependent By using a Cox proportional hazard model, common variants in the PPARG (P12A), C... BeFree 17570749 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent We have genotyped three single nucleotide polymorphisms associated with type 2 d... BeFree 14988278 Detail
0.627 Diabetes Mellitus, Non-Insulin-Dependent By using a Cox proportional hazard model, common variants in the PPARG (P12A), C... BeFree 17570749 Detail
0.439 obesity The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... BeFree 18280041 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Although cross-sectional studies have associated the Pro12Ala polymorphism of PP... BeFree 16567542 Detail
0.012 Impaired glucose tolerance The proline allele at PPARG P12A increases risk for diabetes in persons with imp... BeFree 17213274 Detail
0.163 diabetes mellitus The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gen... BeFree 17898990 Detail
0.002 Diabetes Mellitus, Non-Insulin-Dependent Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... BeFree 16804087 Detail
0.003 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
0.163 diabetes mellitus Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... BeFree 17213274 Detail
0.007 Malignant neoplasm of urinary bladder Using the TaqMan method, we genotyped single nucleotide polymorphisms in interle... BeFree 16110031 Detail
0.003 diabetes mellitus There was no convincing association between any polymorphism of PPARα and PPARγ ... BeFree 21877956 Detail
0.447 Diabetes Mellitus, Non-Insulin-Dependent In fact, we evaluated the effect of seven polymorphisms in the following genes-P... BeFree 23249316 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2)... BeFree 15562396 Detail
0.440 obesity Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activ... BeFree 19733160 Detail
0.013 ulcerative colitis We were unable to replicate in a Caucasian cohort the recent association between... BeFree 23256116 Detail
0.017 Diabetes The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascu... BeFree 22017455 Detail
0.004 Kidney Diseases Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associ... BeFree 17493550 Detail
0.008 Diabetes Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... BeFree 16567542 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Pro12Ala mutation decreases PPARG activity and resistance to NIDDM. BeFree 22937051 Detail
0.220 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
<0.001 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
0.439 obesity The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... BeFree 19766907 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARga... BeFree 16253648 Detail
0.004 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated recepto... BeFree 14981210 Detail
0.343 obesity Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with ... BeFree 17624182 Detail
0.020 coronary artery disease The results of the present study demonstrated that possessing the A allele of RA... BeFree 21861709 Detail
0.003 Non-alcoholic Fatty Liver Disease PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatt... BeFree 21939732 Detail
0.163 diabetes mellitus The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascu... BeFree 22017455 Detail
0.371 Diabetes Mellitus, Insulin-Dependent We aimed to estimate the association between the common Pro12Ala polymorphism of... BeFree 18211635 Detail
0.001 Coronary heart disease Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary he... BeFree 21833536 Detail
<0.001 diabetes mellitus Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... BeFree 16567542 Detail
0.007 Hyperlipidemia Pro12Ala polymorphism in human peroxisome proliferator activated receptor gamma ... BeFree 21669017 Detail
0.102 Diabetic Nephropathy Association of peroxisome proliferator-activated receptor γ Pro12Ala gene polymo... BeFree 24329532 Detail
0.004 Ovarian Diseases In conclusion, the higher frequency of the C--&gt;T substitution in exon 6 of th... BeFree 14671186 Detail
<0.001 Dyslipidemias The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated... BeFree 11158005 Detail
0.102 Diabetic Nephropathy The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamm... BeFree 18467141 Detail
0.003 Diabetes PPARG P12A (rs1801282) was not significantly associated with diabetes or related... BeFree 17903298 Detail
0.003 hyperglycemia The PPARG Pro12Ala polymorphism is associated with a decreased risk of developin... BeFree 16567542 Detail
0.007 gestational diabetes We hypothesized that interaction between PPARG2 Pro12Ala and variants in the pro... BeFree 18162503 Detail
0.008 Diabetes There was no convincing association between any polymorphism of PPARα and PPARγ ... BeFree 21877956 Detail
0.023 Malignant neoplasm of breast A marginally significant increased risk of breast cancer was observed among wome... BeFree 17348446 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent In contrast, the well-documented associations of peroxisome proliferator-activat... BeFree 15561965 Detail
0.004 Malignant neoplasm of stomach We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobac... BeFree 18372284 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Nominal interactions were observed for sleep duration and PPARG rs1801282, CRY2 ... BeFree 24280871 Detail
0.062 polycystic ovary syndrome Insulin resistance is attenuated in women with polycystic ovary syndrome with th... BeFree 11836319 Detail
0.003 multiple sclerosis Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of mu... BeFree 18977277 Detail
0.005 stomach carcinoma Our study suggests that the PPARgamma Pro12Ala polymorphism may be a shared risk... BeFree 17763950 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2)... BeFree 15562396 Detail
0.163 diabetes mellitus The authors highlight these challenges and biases using an illustrative example:... BeFree 20406760 Detail
0.011 colorectal carcinoma Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the P... BeFree 16965392 Detail
0.145 Metabolic syndrome X These results suggest that the PPAR-gamma P12A polymorphism can modulate the ass... BeFree 12630956 Detail
0.003 Arthritis, Psoriatic Meta-analysis of associations between the peroxisome proliferator-activated rece... BeFree 24697566 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala variant in the PPAR-gamma2 (PPARG) gene was genotyped in 571 non-di... BeFree 17700648 Detail
0.145 Metabolic syndrome X There was no convincing association between any polymorphism of PPARα and PPARγ ... BeFree 21877956 Detail
0.017 Diabetes Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... BeFree 16567542 Detail
0.341 Diabetes Mellitus, Non-Insulin-Dependent The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome prolifer... BeFree 24969838 Detail
0.162 polycystic ovary syndrome Insulin resistance is attenuated in women with polycystic ovary syndrome with th... BeFree 11836319 Detail
0.127 Obesity, Morbid In this study, we investigated the association of PPAR-γ gene Pro12Ala (rs180128... BeFree 22410809 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent Nominal interactions were observed for sleep duration and PPARG rs1801282, CRY2 ... BeFree 24280871 Detail
0.614 Diabetes Mellitus, Non-Insulin-Dependent In fact, we evaluated the effect of seven polymorphisms in the following genes-P... BeFree 23249316 Detail
0.163 diabetes mellitus Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasm... BeFree 14729856 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Previous studies have sought to associate the Pro12Ala variant of the peroxisome... BeFree 17985660 Detail
0.017 Diabetes PPARG P12A (rs1801282) was not significantly associated with diabetes or related... BeFree 17903298 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary he... BeFree 21833536 Detail
0.011 colorectal carcinoma This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphi... BeFree 20596649 Detail
0.010 Coronary Arteriosclerosis The meta-analysis of the association of PPARG P12A, C161T polymorphism and coron... BeFree 22987045 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in As... BeFree 19846176 Detail
<0.001 Impaired cognition PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diab... BeFree 18280041 Detail
0.145 Metabolic syndrome X We investigated the synergism between variants at the PPARγ locus (C161T and Pro... BeFree 24243083 Detail
0.003 Diabetes Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... BeFree 17213274 Detail
<0.001 endometrial carcinoma Opposite association of two PPARG variants with cancer: overrepresentation of H4... BeFree 11511919 Detail
0.305 obesity We genotyped known single nucleotide polymorphisms (SNPs) in the adiponectin-enc... BeFree 15830179 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala polymorphism in the gene encoding PPARγ (PPARγ2 gene) influences th... BeFree 21206011 Detail
0.003 prediabetes syndrome Association of Pro12Ala polymorphism in peroxisome proliferator-activated recept... BeFree 17065690 Detail
0.439 obesity The PPARgamma Pro12Ala polymorphism has been associated in several studies with ... BeFree 17408525 Detail
0.005 Peptic Ulcer The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastr... BeFree 18372284 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism a... BeFree 22413765 Detail
0.005 sarcoidosis Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and perox... BeFree 19070258 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is... BeFree 12218380 Detail
0.026 Coronary heart disease Our study in healthy Dutch women in combination with the meta-analyses of previo... BeFree 18561518 Detail
0.439 obesity The association of the C1431T silent mutation and the Pro12Ala missense transver... BeFree 18250615 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent These results suggest that the PPARgamma is a thrifty gene and that the Pro12Ala... BeFree 10777704 Detail
<0.001 Diabetes Mellitus, Non-Insulin-Dependent Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T mi... BeFree 25262148 Detail
0.258 Hypertensive disease To explore the relationship between the genetic polymorphisms of PPARgamma (Pro1... BeFree 19651920 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Although the study was carried out on a sufficiently large sample, the conclusio... BeFree 10389855 Detail
0.007 HIV Infections PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related li... BeFree 19534662 Detail
0.002 Impaired glucose tolerance Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... BeFree 16804087 Detail
0.145 Metabolic syndrome X PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribu... BeFree 22168210 Detail
<0.001 Coronary Arteriosclerosis The meta-analysis of the association of PPARG P12A, C161T polymorphism and coron... BeFree 22987045 Detail
0.062 polycystic ovary syndrome Association of Pro12Ala polymorphism in peroxisome proliferator-activated recept... BeFree 22729915 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent The P12A variant in the PPARG gene and the E23K polymorphism in KCNJ11 are both ... BeFree 17994213 Detail
0.145 Metabolic syndrome X Healthy men, in particular nonsmokers, carrying the Ala12 allele of PPARG rs1801... BeFree 19745552 Detail
<0.001 Diabetes Mellitus, Non-Insulin-Dependent Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a co... BeFree 25063576 Detail
0.008 diabetic retinopathy Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be asso... BeFree 18077048 Detail
0.374 Diabetes Mellitus, Non-Insulin-Dependent Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (... BeFree 17439324 Detail
<0.001 Presenile dementia We also investigated the possible association between PPARgamma Pro12Ala polymor... BeFree 21970714 Detail
0.001 Helicobacter pylori infection Association between peroxisome proliferator-activated receptor-γ gene polymorphi... BeFree 20568969 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mell... BeFree 16920849 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Association between the P12A and c1431t polymorphisms in the peroxisome prolifer... BeFree 11409297 Detail
0.439 obesity Polymorphisms of the peroxisome proliferator-activated receptor-γ (rs1801282) an... BeFree 25928419 Detail
0.017 Diabetes The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... BeFree 17493550 Detail
0.004 Ovarian Diseases In conclusion, our results confirm that adiponectin concentrations are similar i... BeFree 15472214 Detail
0.011 Kidney Diseases Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T mi... BeFree 25262148 Detail
0.062 polycystic ovary syndrome Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma ge... BeFree 16785159 Detail
0.466 Diabetes Mellitus, Non-Insulin-Dependent In contrast, the well-documented associations of peroxisome proliferator-activat... BeFree 15561965 Detail
0.094 arteriosclerosis Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro1... BeFree 25159899 Detail
0.011 endometriosis Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala pol... BeFree 15136115 Detail
<0.001 premature menopause Four SNPs (rs2167270 of LEP and rs1801282, rs2120825, and rs3856806 of PPARγ) we... BeFree 22537818 Detail
0.017 Diabetes Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12... BeFree 17941898 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The risk associated with the presence of T2D was modified both by IGF2BP2_rs4402... BeFree 22419714 Detail
0.003 Graves Disease The distribution of the Pro(12)Ala PPAR gamma gene polymorphism is equally prese... BeFree 18624999 Detail
0.005 dementia We also investigated the possible association between PPARgamma Pro12Ala polymor... BeFree 21970714 Detail
0.026 Coronary heart disease Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident... BeFree 22515931 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala polymorphism in the PPAR-gamma gene has been associated with reduce... BeFree 18639367 Detail
0.010 hyperinsulinism Our results suggest that the Pro12Ala polymorphism of the PPARgamma-2 gene promo... BeFree 12370112 Detail
0.026 Coronary heart disease The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamm... BeFree 23300871 Detail
<0.001 Pyruvate dehydrogenase E3-binding protein deficiency Pro12Ala sequence variant of the PPARG gene is associated with postprandial hype... BeFree 16916989 Detail
0.020 coronary artery disease The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamm... BeFree 23300871 Detail
0.163 diabetes mellitus The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... BeFree 17493550 Detail
0.002 Rectal Carcinoma For rectal cancer there was a significant interaction between the Bsm1/polyA pol... BeFree 16489531 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Conflicting evidence exists as to whether the Pro12Ala single nucleotide polymor... BeFree 18466209 Detail
0.005 stomach carcinoma We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobac... BeFree 18372284 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Cardiovascular risk factors related to the PPARγ Pro12Ala polymorphism in patien... BeFree 22017455 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARga... BeFree 16253648 Detail
<0.001 proliferative diabetic retinopathy Association of Pro12Ala polymorphism in peroxisome proliferator activated recept... BeFree 23559865 Detail
0.062 polycystic ovary syndrome Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma ge... BeFree 16316841 Detail
0.439 obesity Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated rec... BeFree 12679463 Detail
<0.001 Diabetic Nephropathy The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... BeFree 17493550 Detail
0.163 diabetes mellitus The role of the Pro12Ala polymorphism in peroxisome proliferator-activated recep... BeFree 17563457 Detail
0.023 Malignant neoplasm of urinary bladder Using the TaqMan method, we genotyped single nucleotide polymorphisms in interle... BeFree 16110031 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent A population-attributable risk of approximately 50% for the Pro12Pro genotype in... BeFree 16822823 Detail
0.021 Cardiovascular Diseases The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamm... BeFree 18467141 Detail
0.287 Diabetes Mellitus, Non-Insulin-Dependent We investigated the effects of the common polymorphisms in the peroxisome prolif... BeFree 20045142 Detail
0.126 Metabolic Diseases In conclusion, the PPARG Pro12Ala polymorphism might represent a genetic suscept... BeFree 17259396 Detail
0.032 myocardial infarction Association between Pro12Ala polymorphism of peroxisome proliferator-activated r... BeFree 16881538 Detail
0.006 Malignant neoplasm of breast This meta-analysis supported the fact that the G allele of PPAR‑γ2 Pro12Ala (rs1... BeFree 24141935 Detail
0.010 hyperinsulinism We investigated individual and combined associations of Pro12Ala and His447His p... BeFree 23748472 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma c... BeFree 15782399 Detail
0.003 polycystic ovary syndrome The association between Pro12Ala polymorphism in peroxisome proliferator-activat... BeFree 22729915 Detail
0.004 Kidney Diseases Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated... BeFree 22619290 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent We were able to confirm only one association, that of the common Pro12Ala polymo... BeFree 10973253 Detail
0.001 Coronary heart disease Our study in healthy Dutch women in combination with the meta-analyses of previo... BeFree 18561518 Detail
0.002 Carcinoma of bladder Using the TaqMan method, we genotyped single nucleotide polymorphisms in interle... BeFree 16110031 Detail
0.153 atherosclerosis Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro1... BeFree 25159899 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The influence of the Pro12Ala mutation of the PPAR-gamma receptor gene on metabo... BeFree 12406034 Detail
0.316 Diabetes Mellitus, Non-Insulin-Dependent In fact, we evaluated the effect of seven polymorphisms in the following genes-P... BeFree 23249316 Detail
<0.001 Cardiovascular Diseases We examined the relationship between two PPAR-gamma gene polymorphisms, namely t... BeFree 18417957 Detail
<0.001 renal cell carcinoma Opposite association of two PPARG variants with cancer: overrepresentation of H4... BeFree 11511919 Detail
<0.001 Kidney Diseases Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T mi... BeFree 25262148 Detail
0.017 Diabetes The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PP... BeFree 19436234 Detail
0.004 Ovarian Diseases In the present study we have examined the relationship of the Pro(12)Ala polymor... BeFree 11836319 Detail
0.004 Diabetes Mellitus, Non-Insulin-Dependent The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2)... BeFree 15562396 Detail
0.439 obesity The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome prolifer... BeFree 24969838 Detail
0.316 Diabetes Mellitus, Non-Insulin-Dependent To analyze the relationship between the peroxisome proliferator-activated recept... BeFree 12218380 Detail
0.163 diabetes mellitus The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... BeFree 17052804 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor (PPA... BeFree 19808901 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent Association between the P12A and c1431t polymorphisms in the peroxisome prolifer... BeFree 11409297 Detail
0.163 diabetes mellitus The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PP... BeFree 19436234 Detail
0.007 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
0.009 lipodystrophy PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related li... BeFree 19534662 Detail
0.143 diabetes mellitus Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... BeFree 16567542 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) P... BeFree 17434720 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... BeFree 16804087 Detail
0.010 Coronary Arteriosclerosis The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamm... BeFree 23300871 Detail
0.037 colorectal cancer We have studied the association between single nucleotide polymorphisms in the i... BeFree 12839942 Detail
0.004 Ovarian Diseases We did not find statistically significant differences with peroxisome proliferat... BeFree 16600233 Detail
0.039 colorectal cancer Influence of the C161T but not Pro12Ala polymorphism in the peroxisome prolifera... BeFree 16108832 Detail
0.007 Overweight PPARG rs1801282(G) conferred a higher risk of altered insulin (OR=12.31, P=0.003... BeFree 25923461 Detail
0.017 Diabetes The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... BeFree 17052804 Detail
0.439 obesity The Pro12Ala polymorphism of PPARG was significantly associated with obesity (OR... BeFree 25127329 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala polymorphism (rs1801282), a nonsynonymous substitution of peroxisom... BeFree 19745552 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes wi... BeFree 14730381 Detail
0.016 diabetes mellitus There was no convincing association between any polymorphism of PPARα and PPARγ ... BeFree 21877956 Detail
0.002 obesity The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARga... BeFree 16253648 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent We did not find any significant association between three SNPs in the PGC-1alpha... BeFree 17479445 Detail
0.001 Ischemic Cerebrovascular Accident Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associ... BeFree 17359638 Detail
0.004 Diabetes Mellitus, Non-Insulin-Dependent Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T mi... BeFree 25262148 Detail
0.005 stomach carcinoma Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism could be ... BeFree 25824760 Detail
0.102 Diabetic Nephropathy Relationship between PPARγ Pro12Ala gene polymorphism and type 2 diabetic nephro... BeFree 24303936 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated... BeFree 22619290 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary he... BeFree 21833536 Detail
<0.001 Insulin resistance syndrome Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Dani... BeFree 12161548 Detail
0.004 Diabetes Mellitus, Non-Insulin-Dependent An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) P... BeFree 17434720 Detail
<0.001 Impaired cognition The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... BeFree 19766907 Detail
<0.001 Adenoma of large intestine Larger studies are needed to validate these results, which suggest that the PPAR... BeFree 15564289 Detail
0.003 obesity The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated recepto... BeFree 14981210 Detail
0.017 Diabetes PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diab... BeFree 18280041 Detail
0.004 Malignant tumor of colon There was a significant interaction between the -200A&gt;C IGFBP3 polymorphism a... BeFree 16489531 Detail
0.439 obesity PPARγ Pro12Ala interacts with fat intake for obesity and weight loss in a behavi... BeFree 22102511 Detail
0.017 Diabetes The role of the Pro12Ala polymorphism in peroxisome proliferator-activated recep... BeFree 17563457 Detail
0.005 Lipid Metabolism Disorders The aim of the present study was to investigate the relation between TG-related ... BeFree 12042669 Detail
0.439 obesity We investigated a possible association of PPARg2 Pro12Ala polymorphism with obes... BeFree 22653647 Detail
0.009 hyperglycemia The PPARG Pro12Ala polymorphism is associated with a decreased risk of developin... BeFree 16567542 Detail
0.011 colorectal carcinoma Influence of the C161T but not Pro12Ala polymorphism in the peroxisome prolifera... BeFree 16108832 Detail
0.003 Diabetes There was no convincing association between any polymorphism of PPARα and PPARγ ... BeFree 21877956 Detail
0.439 obesity In conclusion, the higher frequency of the C--&gt;T substitution in exon 6 of th... BeFree 14671186 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent In contrast, the well-documented associations of peroxisome proliferator-activat... BeFree 15561965 Detail
<0.001 metabolic disturbance Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro1... BeFree 25159899 Detail
0.017 Diabetes Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasm... BeFree 14729856 Detail
<0.001 premature menopause Four SNPs (rs2167270 of LEP and rs1801282, rs2120825, and rs3856806 of PPARγ) we... BeFree 22537818 Detail
0.011 colorectal carcinoma In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma... BeFree 15860437 Detail
0.015 Carcinogenesis Association between peroxisome proliferator-activated receptor-γ gene polymorphi... BeFree 20568969 Detail
<0.001 colorectal cancer This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphi... BeFree 20596649 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... BeFree 17213274 Detail
0.128 Dyslipidemias The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated... BeFree 11158005 Detail
0.102 Diabetic Nephropathy The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... BeFree 17493550 Detail
0.010 gestational diabetes We hypothesized that interaction between PPARG2 Pro12Ala and variants in the pro... BeFree 18162503 Detail
0.011 endometriosis Association of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala polym... BeFree 20560917 Detail
0.163 diabetes mellitus Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with... BeFree 21795447 Detail
0.007 Overweight Our study indicates that PPARG rs1801282 may significantly predict overweight, B... BeFree 25182148 Detail
0.032 Metabolic syndrome X The Pro12Ala PPARG sequence variant together with a non-E3/E3 APOE genotype is a... BeFree 16916989 Detail
0.258 Hypertensive disease The Pro12Ala and the 4a/b polymorphisms of the peroxisome proliferator-activated... BeFree 15662218 Detail
0.163 diabetes mellitus There appears to be certain genes which predispose Indians to diabetes while oth... BeFree 17496355 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala polymorphism of PPARG was significantly associated with obesity (OR... BeFree 25127329 Detail
0.003 diabetes mellitus Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... BeFree 17213274 Detail
0.163 diabetes mellitus Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12... BeFree 17941898 Detail
0.011 colorectal carcinoma We have studied the association between single nucleotide polymorphisms in the i... BeFree 12839942 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The association between the peroxisome proliferator-activated receptor-gamma2 (P... BeFree 20179158 Detail
0.163 diabetes mellitus Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... BeFree 16567542 Detail
0.006 Inflammatory Bowel Diseases Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (P... BeFree 19104705 Detail
0.004 Ovarian Diseases Our findings suggest that Pro12Ala PPAR-gamma gene polymorphism may be protectiv... BeFree 16316841 Detail
0.039 colorectal cancer This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphi... BeFree 20596649 Detail
0.163 diabetes mellitus Pro12Ala missense mutation of the peroxisome proliferator activated receptor gam... BeFree 9918859 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated recepto... BeFree 14981210 Detail
0.010 hyperinsulinism The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is as... BeFree 15853827 Detail
<0.001 colorectal carcinoma In this study, we evaluated the association between colorectal cancer and specif... BeFree 16489531 Detail
0.400 obesity The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome prolifer... BeFree 24969838 Detail
0.003 Hypercholesterolemia For the Pro12Ala polymorphism in PPARγ, although patients with the Pro/Ala genot... BeFree 23145084 Detail
0.006 rheumatoid arthritis The purpose of this study was to examine whether a Proline (Pro)-to-Alanine (Ala... BeFree 24697566 Detail
0.162 polycystic ovary syndrome To investigate the influence of the peroxisome proliferator activated receptor g... BeFree 22527903 Detail
0.004 Malignant neoplasm of stomach Our study suggests that the PPARgamma Pro12Ala polymorphism may be a shared risk... BeFree 17763950 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegre... BeFree 25157153 Detail
0.439 obesity Here, we investigated the expression of APM1 in adipose tissue and studied the r... BeFree 16231017 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident... BeFree 22515931 Detail
0.010 hyperinsulinism Pro12Ala, a missense mutation in exon 2 of PPARG, reduces transcriptional activi... BeFree 20368233 Detail
0.014 Malignant neoplasm of prostate Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (P... BeFree 12609711 Detail
0.007 gestational diabetes Quantitative assessment of the influence of PPARG P12A polymorphism on gestation... BeFree 23054024 Detail
0.287 Diabetes Mellitus, Non-Insulin-Dependent The present study demonstrates that the AA genotype of the Gly482Ser polymorphis... BeFree 15782399 Detail
0.007 Overweight The goal of this study was to examine whether the Pro12Ala polymorphism of perox... BeFree 22102511 Detail
0.004 Malignant neoplasm of stomach Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism could be ... BeFree 25824760 Detail
<0.001 Acne Vulgaris The Pro12Ala polymorphism of the gene for peroxisome proliferator activated rece... BeFree 24984871 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a co... BeFree 25063576 Detail
0.017 Diabetes There appears to be certain genes which predispose Indians to diabetes while oth... BeFree 17496355 Detail
0.037 Metabolic syndrome X PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribu... BeFree 22168210 Detail
<0.001 endometrial carcinoma No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer ... BeFree 15608564 Detail
0.163 diabetes mellitus PPARG P12A (rs1801282) was not significantly associated with diabetes or related... BeFree 17903298 Detail
0.005 Carcinoma of bladder Using the TaqMan method, we genotyped single nucleotide polymorphisms in interle... BeFree 16110031 Detail
0.007 Metabolic syndrome X There was no convincing association between any polymorphism of PPARα and PPARγ ... BeFree 21877956 Detail
<0.001 Kidney Diseases Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T mi... BeFree 25262148 Detail
0.139 Alzheimer's disease Lack of genetic associations between PPAR-γ gene rs1801282 polymorphism and Alzh... BeFree 25770052 Detail
0.004 Ovarian Diseases The Pro12Ala polymorphism of the PPARgamma gene is associated with increased ins... BeFree 15853827 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent To explore the way that population description is used to replicate and/or exten... BeFree 20157827 Detail
0.007 Hyperlipidemia A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-... BeFree 11248748 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Common polymorphisms of the peroxisome proliferator-activated receptor-gamma (Pr... BeFree 20045142 Detail
0.003 breast carcinoma This meta-analysis supported the fact that the G allele of PPAR‑γ2 Pro12Ala (rs1... BeFree 24141935 Detail
0.001 Helicobacter pylori infection The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastr... BeFree 18372284 Detail
0.452 Diabetes Mellitus, Non-Insulin-Dependent Four of the nine SNPs revealed a significant association with T2D; PPARG2 (Pro12... BeFree 18598350 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome prolifer... BeFree 24969838 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The common Pro12Ala polymorphism in PPARgamma is associated with lower diastolic... BeFree 12923397 Detail
<0.001 Coronary Arteriosclerosis Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary he... BeFree 21833536 Detail
0.020 coronary artery disease No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery ... BeFree 17322631 Detail
0.011 Acute coronary syndrome PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospec... BeFree 19500413 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Genome-wide trans-ancestry meta-analysis provides insight into the genetic archi... GWASCAT 24509480 Detail
0.003 Diabetes The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... BeFree 17493550 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The common Pro12Ala polymorphism in peroxisome proliferator-activated receptor-γ... BeFree 23014256 Detail
0.439 obesity The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator... BeFree 15784141 Detail
0.007 gestational diabetes Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotype... BeFree 21795447 Detail
0.009 sarcoidosis Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and perox... BeFree 19070258 Detail
<0.001 colorectal carcinoma In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma... BeFree 15860437 Detail
0.145 Metabolic syndrome X Associations between C1431T and Pro12Ala variants of PPARγ gene and their haplot... BeFree 24464185 Detail
0.452 Diabetes Mellitus, Non-Insulin-Dependent The risk associated with the presence of T2D was modified both by IGF2BP2_rs4402... BeFree 22419714 Detail
0.287 Diabetes Mellitus, Non-Insulin-Dependent In a large sample of the Caucasians the rs8192673 of the PGC-1α gene and the rs1... BeFree 25928419 Detail
0.008 diabetic retinopathy Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma c... BeFree 15782399 Detail
0.439 obesity Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala vari... BeFree 11158005 Detail
0.062 polycystic ovary syndrome A meta-analysis on the association between PPAR-γ Pro12Ala polymorphism and poly... BeFree 22527903 Detail
0.003 Non-alcoholic Fatty Liver Disease Association between the Pro12Ala polymorphism of PPAR-γ gene and the non-alcohol... BeFree 23891820 Detail
0.287 Diabetes Mellitus, Non-Insulin-Dependent Evidence for interaction between PPARG Pro12Ala and PPARGC1A Gly482Ser polymorph... BeFree 19536736 Detail
0.134 colon carcinoma There was a significant interaction between the -200A&gt;C IGFBP3 polymorphism a... BeFree 16489531 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Polymorphism of peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala in... BeFree 21968139 Detail
<0.001 Carotid Atherosclerosis We investigated the relationship between 2 common PPARG polymorphisms, namely P1... BeFree 15284449 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala polymorp... BeFree 19846795 Detail
0.439 obesity Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activ... BeFree 19733160 Detail
0.145 Metabolic syndrome X The Pro12Ala PPARgamma polymorphism does not seem to be associated with BMI or m... BeFree 19609844 Detail
0.439 obesity The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARga... BeFree 16253648 Detail
0.003 Malignant neoplasm of pancreas Association between the peroxisome proliferator-activated receptor gamma Pro12Al... BeFree 19436234 Detail
<0.001 colorectal cancer In this study, we evaluated the association between colorectal cancer and specif... BeFree 16489531 Detail
0.163 diabetes mellitus Our findings suggest that Pro12Ala PPAR-gamma gene polymorphism may be protectiv... BeFree 16316841 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamm... BeFree 18467141 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent These results suggest that in the Taiwanese, the Pro12Ala PPARgamma2 gene varian... BeFree 11079814 Detail
0.010 Coronary Arteriosclerosis Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident... BeFree 22515931 Detail
0.062 polycystic ovary syndrome The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is as... BeFree 15853827 Detail
0.026 colorectal cancer We have studied the association between single nucleotide polymorphisms in the i... BeFree 12839942 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Polymorphisms of the peroxisome proliferator-activated receptor-γ (rs1801282) an... BeFree 25928419 Detail
0.614 Diabetes Mellitus, Non-Insulin-Dependent Four of the nine SNPs revealed a significant association with T2D; PPARG2 (Pro12... BeFree 18598350 Detail
0.062 polycystic ovary syndrome Lack of an association between peroxisome proliferator-activated receptor-gamma ... BeFree 15472214 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Evidence for interaction between PPARG Pro12Ala and PPARGC1A Gly482Ser polymorph... BeFree 19536736 Detail
<0.001 colorectal carcinoma This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphi... BeFree 20596649 Detail
<0.001 acute myocardial infarction The alanine allele of P12A polymorphism in PPARG gene in a few studies has been ... BeFree 18561518 Detail
0.564 Diabetes Mellitus, Non-Insulin-Dependent Nominal interactions were observed for sleep duration and PPARG rs1801282, CRY2 ... BeFree 24280871 Detail
0.102 obesity The aim of this study was to clarify whether common single nucleotide polymorphi... BeFree 25928419 Detail
<0.001 Pediatric Obesity Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphi... BeFree 19634985 Detail
0.258 Hypertensive disease The data suggest a contribution of the Pro12Ala polymorphism of PPARgamma to gen... BeFree 15563983 Detail
<0.001 hyperglycemia The PPARG Pro12Ala polymorphism is associated with a decreased risk of developin... BeFree 16567542 Detail
0.439 obesity Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with ... BeFree 17624182 Detail
0.012 Impaired glucose tolerance Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... BeFree 16804087 Detail
0.013 Malignant tumor of colon There was a significant interaction between the -200A&gt;C IGFBP3 polymorphism a... BeFree 16489531 Detail
0.001 Coronary heart disease The meta-analysis of the association of PPARG P12A, C161T polymorphism and coron... BeFree 22987045 Detail
0.145 Metabolic syndrome X Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Dani... BeFree 12161548 Detail
0.094 arteriosclerosis The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated recept... BeFree 25096510 Detail
0.007 colorectal carcinoma We have studied the association between single nucleotide polymorphisms in the i... BeFree 12839942 Detail
0.163 diabetes mellitus Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabete... BeFree 23006958 Detail
0.002 Rectal Carcinoma For rectal cancer there was a significant interaction between the Bsm1/polyA pol... BeFree 16489531 Detail
<0.001 Impaired glucose tolerance Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... BeFree 16804087 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Is it time to conduct a hypothesis-driven large-scale exercise training interven... BeFree 22672138 Detail
0.321 Diabetes Mellitus, Non-Insulin-Dependent Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is... BeFree 12218380 Detail
0.008 diabetic retinopathy The association of non-synonymous substitution polymorphism rs1801282 (c.34C&gt;... BeFree 23559865 Detail
<0.001 Diabetes Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... BeFree 16567542 Detail
0.439 obesity A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-... BeFree 11248748 Detail
0.012 Overweight PPARG rs1801282(G) conferred a higher risk of altered insulin (OR=12.31, P=0.003... BeFree 25923461 Detail
0.439 obesity The peroxisome proliferator-activated receptor gamma 2 Pro12Ala mutation is asso... BeFree 10873398 Detail
0.003 diabetes mellitus PPARG P12A (rs1801282) was not significantly associated with diabetes or related... BeFree 17903298 Detail
0.145 Metabolic syndrome X Pro12Ala sequence variant of the PPARG gene is associated with postprandial hype... BeFree 16916989 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associ... BeFree 17493550 Detail
0.001 Helicobacter pylori infection Nevertheless, prospectively designed cohort studies are needed to further invest... BeFree 25824760 Detail
0.006 rheumatoid arthritis These observations suggest that Pro12Ala (rs1801282), a coding variant in the PP... BeFree 23633103 Detail
<0.001 Impaired glucose tolerance The proline allele at PPARG P12A increases risk for diabetes in persons with imp... BeFree 17213274 Detail
0.017 Diabetes Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... BeFree 17213274 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator... BeFree 15784141 Detail
<0.001 Diabetes Mellitus, Non-Insulin-Dependent Hence, our aim was to develop a low-cost method for the validation of PPARG (Pro... BeFree 25063576 Detail
0.139 obesity In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotyp... BeFree 24200052 Detail
0.374 Diabetes Mellitus, Non-Insulin-Dependent Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mell... BeFree 16920849 Detail
0.026 Coronary heart disease No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery ... BeFree 17322631 Detail
0.003 diabetes mellitus The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... BeFree 17493550 Detail
0.145 Metabolic syndrome X The frequencies of 2 common polymorphisms of the PPARgamma gene, Pro12Ala single... BeFree 18362424 Detail
<0.001 gastric adenocarcinoma The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastr... BeFree 18372284 Detail
0.039 colorectal cancer Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the P... BeFree 16965392 Detail
0.017 Diabetes The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gen... BeFree 17898990 Detail
0.026 Coronary heart disease The aim was to investigate if the polymorphism PPARgamma2 Pro12Ala, which encode... BeFree 19500413 Detail
<0.001 gestational diabetes The other polymorphisms studied were not significantly associated with gestation... BeFree 17342473 Detail
0.439 obesity The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamm... BeFree 25182148 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Examining the relationships between the Pro12Ala variant in PPARG and Type 2 dia... BeFree 16401314 Detail
0.020 Ovarian Diseases Compared with first-degree relatives of PCOS subjects with the Pro12Pro polymorp... BeFree 16316841 Detail
0.374 Diabetes Mellitus, Non-Insulin-Dependent Together, these results showed that PPARG Pro12Ala and PPARGC1A Gly482Ser varian... BeFree 19536736 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (... BeFree 17439324 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The data suggest a contribution of the Pro12Ala polymorphism of PPARgamma to gen... BeFree 15563983 Detail
0.009 lipodystrophy In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegre... BeFree 25157153 Detail
0.001 Ischemic stroke Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associ... BeFree 17359638 Detail
<0.001 acne The Pro12Ala polymorphism of the gene for peroxisome proliferator activated rece... BeFree 24984871 Detail
0.002 obesity The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated... BeFree 11158005 Detail
0.003 Non-alcoholic Fatty Liver Disease Meta-analysis of associations between the peroxisome proliferator-activated rece... BeFree 24697566 Detail
0.032 myocardial infarction We conclude that PPARg2 Pro12Ala polymorphisms are associated with increased ris... BeFree 22653647 Detail
0.439 obesity The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... BeFree 17052804 Detail
0.017 Diabetes The authors highlight these challenges and biases using an illustrative example:... BeFree 20406760 Detail
0.010 Coronary Arteriosclerosis No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery ... BeFree 17322631 Detail
0.010 prostate carcinoma Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (P... BeFree 12609711 Detail
0.094 Diabetes Mellitus, Non-Insulin-Dependent In fact, we evaluated the effect of seven polymorphisms in the following genes-P... BeFree 23249316 Detail
0.003 Osteoarthritis, Knee Prevalence of the Pro12Ala missense mutation in the PPARG2 gene in Kuwaiti patie... BeFree 21245597 Detail
<0.001 endometrial carcinoma Opposite association of two PPARG variants with cancer: overrepresentation of H4... BeFree 11511919 Detail
0.004 Ovarian Diseases We suggest that Pro12Ala polymorphism of the PPAR-gamma gene may be a modifier o... BeFree 16785159 Detail
0.002 colon carcinoma There was a significant interaction between the -200A&gt;C IGFBP3 polymorphism a... BeFree 16489531 Detail
0.439 obesity The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gen... BeFree 17898990 Detail
0.322 Diabetes Mellitus, Non-Insulin-Dependent PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in As... BeFree 19846176 Detail
0.081 diabetic retinopathy The present study demonstrates that the AA genotype of the Gly482Ser polymorphis... BeFree 15782399 Detail
0.062 polycystic ovary syndrome Association between the Pro12Ala polymorphism of PPAR-γ gene and the polycystic ... BeFree 22564702 Detail
<0.001 Metabolic syndrome X Our objective was to search for differences in genotypes of peroxisome prolifera... BeFree 16216916 Detail
0.015 breast carcinoma A marginally significant increased risk of breast cancer was observed among wome... BeFree 17348446 Detail
0.026 Coronary heart disease The meta-analysis of the association of PPARG P12A, C161T polymorphism and coron... BeFree 22987045 Detail
0.140 Metabolic syndrome X In the group of participants with PPARγ Pro12Ala or Ala12Ala genotypes, those wi... BeFree 24200052 Detail
0.007 HIV Infections The presence of PPARγ2 rs1801282 G allele (Ala variant) was associated with incr... BeFree 25072612 Detail
0.102 Diabetic Nephropathy Pro12Ala polymorphism in the PPARG gene contributes to the development of diabet... BeFree 19837787 Detail
0.004 pancreatic carcinoma Association between the peroxisome proliferator-activated receptor gamma Pro12Al... BeFree 19436234 Detail
0.004 Diabetes Mellitus, Non-Insulin-Dependent Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... BeFree 16804087 Detail
0.163 diabetes mellitus PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diab... BeFree 18280041 Detail
0.004 Ovarian Diseases This study has shown that both Pro12Ala and His447His polymorphisms of PPAR-gamm... BeFree 19549442 Detail
0.439 obesity The single nucleotide polymorphisms (SNPs) of the above genes, such as GNB3-C825... BeFree 24827746 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: ... BeFree 18598350 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be asso... BeFree 18077048 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... BeFree 17213274 Detail
0.026 Coronary heart disease We examined the relationship between PPARG2 P12A and CHD risk in women (Nurses' ... BeFree 15920035 Detail
0.039 colorectal cancer In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma... BeFree 15860437 Detail
<0.001 Diabetic Nephropathy We conclude that P12A and C161T polymorphisms of the PPAR-gamma gene are importa... BeFree 18417957 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent The protective role of the Ala allele in the Pro12Ala polymorphism of PPARγ on t... BeFree 21795447 Detail
0.021 Cardiovascular Diseases Two PPARg common polymorphisms, Pro12Ala and 161C&gt;T, have been found to be as... BeFree 19117570 Detail
<0.001 colorectal cancer In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma... BeFree 15860437 Detail
0.153 atherosclerosis The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated recept... BeFree 25096510 Detail
0.006 Inflammatory Bowel Diseases Association between the Pro12Ala polymorphism of peroxisome proliferator-activat... BeFree 22276212 Detail
0.439 obesity The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated recepto... BeFree 14981210 Detail
0.439 obesity In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotyp... BeFree 24200052 Detail
0.017 Diabetes Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with... BeFree 21795447 Detail
0.340 Diabetes Mellitus, Non-Insulin-Dependent Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (H... BeFree 25839936 Detail
0.083 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.393 Diabetes Mellitus, Non-Insulin-Dependent Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... BeFree 22569928 Detail
0.214 Diabetes Mellitus, Non-Insulin-Dependent Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... BeFree 22569928 Detail
0.466 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.614 Diabetes Mellitus, Non-Insulin-Dependent Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (H... BeFree 25839936 Detail
0.614 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.214 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.466 Diabetes Mellitus, Non-Insulin-Dependent Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... BeFree 22569928 Detail
0.336 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.314 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.452 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.466 Diabetes Mellitus, Non-Insulin-Dependent Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (H... BeFree 25839936 Detail
0.290 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.055 Diabetes Mellitus, Non-Insulin-Dependent Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (H... BeFree 25839936 Detail
0.090 Diabetes Mellitus, Non-Insulin-Dependent Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... BeFree 22569928 Detail
0.296 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.003 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.090 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.042 Diabetes Mellitus, Non-Insulin-Dependent Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (H... BeFree 25839936 Detail
0.340 Diabetes Mellitus, Non-Insulin-Dependent Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... BeFree 22569928 Detail
0.452 Diabetes Mellitus, Non-Insulin-Dependent Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... BeFree 22569928 Detail
0.341 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.181 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.057 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.017 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.032 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.176 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.121 Diabetes Mellitus, Non-Insulin-Dependent Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (H... BeFree 25839936 Detail
0.009 gestational diabetes 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HH... BeFree 22591707 Detail
0.090 Diabetes Mellitus, Non-Insulin-Dependent Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (H... BeFree 25839936 Detail
0.025 Diabetes Mellitus, Non-Insulin-Dependent Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (H... BeFree 25839936 Detail
0.293 Diabetes Mellitus, Non-Insulin-Dependent To examine the association of type 2 diabetes susceptibility loci and visceral f... BeFree 22377712 Detail
0.002 Diabetes A total of 792 patients with T2DM were enrolled and categorized into two groups:... BeFree 25274455 Detail
<0.001 Retinal Diseases A total of 792 patients with T2DM were enrolled and categorized into two groups:... BeFree 25274455 Detail
<0.001 Retinal Diseases A total of 792 patients with T2DM were enrolled and categorized into two groups:... BeFree 25274455 Detail
0.002 diabetes mellitus A total of 792 patients with T2DM were enrolled and categorized into two groups:... BeFree 25274455 Detail
0.012 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.008 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.183 Crohn Disease The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.009 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.013 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.009 Crohn Disease The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
<0.001 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.327 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.001 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.009 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.131 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.126 Crohn Disease The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.295 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.034 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
<0.001 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
0.187 ulcerative colitis The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL... BeFree 24971461 Detail
Annotation

Annotations

DescrptionSourceLinks
NM_138711.6(PPARG):c.-8-28078C>G AND not specified ClinVar Detail
NM_138711.6(PPARG):c.-8-28078C>G AND Diabetes Mellitus, Noninsulin-Dependent, with Acanthosis Nigric... ClinVar Detail
NM_138711.6(PPARG):c.-8-28078C>G AND PPARG-related familial partial lipodystrophy ClinVar Detail
NM_138711.6(PPARG):c.-8-28078C>G AND Obesity ClinVar Detail
NM_138711.6(PPARG):c.-8-28078C>G AND not provided ClinVar Detail
Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP A19G), the leptin r... DisGeNET Detail
Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP A19G), the leptin r... DisGeNET Detail
Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP A19G), the leptin r... DisGeNET Detail
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... DisGeNET Detail
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... DisGeNET Detail
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... DisGeNET Detail
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... DisGeNET Detail
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... DisGeNET Detail
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... DisGeNET Detail
Seven variants displaying conflicting results in previous reports and supposedly implicated in the s... DisGeNET Detail
Seven variants displaying conflicting results in previous reports and supposedly implicated in the s... DisGeNET Detail
Seven variants displaying conflicting results in previous reports and supposedly implicated in the s... DisGeNET Detail
Seven variants displaying conflicting results in previous reports and supposedly implicated in the s... DisGeNET Detail
The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs1801282) are two risk ... DisGeNET Detail
The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs1801282) are two risk ... DisGeNET Detail
The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs1801282) are two risk ... DisGeNET Detail
The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs1801282) are two risk ... DisGeNET Detail
The variables significantly associated with SVR in a multivariate analysis were HCV-genotype (GT) 3 ... DisGeNET Detail
The variables significantly associated with SVR in a multivariate analysis were HCV-genotype (GT) 3 ... DisGeNET Detail
The variables significantly associated with SVR in a multivariate analysis were HCV-genotype (GT) 3 ... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
We genotyped 7 single-nucleotide polymorphisms (SNPs) in PPARG2 (rs1801282), ADIPOQ (rs1501299), ADR... DisGeNET Detail
The PPAR-γ2 gene rs1801282 polymorphism was significantly associated with type 2 diabetes susceptibi... DisGeNET Detail
The PPAR-γ2 gene rs1801282 polymorphism was significantly associated with type 2 diabetes susceptibi... DisGeNET Detail
The PPAR-γ2 gene rs1801282 polymorphism was significantly associated with type 2 diabetes susceptibi... DisGeNET Detail
Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone... DisGeNET Detail
Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone... DisGeNET Detail
Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone... DisGeNET Detail
Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone... DisGeNET Detail
We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), TNFalpha (-308G&gt;A... DisGeNET Detail
We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), TNFalpha (-308G&gt;A... DisGeNET Detail
We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), TNFalpha (-308G&gt;A... DisGeNET Detail
We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), TNFalpha (-308G&gt;A... DisGeNET Detail
We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), TNFalpha (-308G&gt;A... DisGeNET Detail
We studied the association of SNPs in the IL-6 (-174G&gt;C), IL-8 (-251T&gt;A), TNFalpha (-308G&gt;A... DisGeNET Detail
The frequency distribution of rare alleles for PPARα (L162V) and PPARγ (P12A and H449H) was compared... DisGeNET Detail
The objective of this study was to analyze the polymorphisms Leu162Val of PPARα and Pro12Ala of PPAR... DisGeNET Detail
The frequency distribution of rare alleles for PPARα (L162V) and PPARγ (P12A and H449H) was compared... DisGeNET Detail
The objective of this study was to analyze the polymorphisms Leu162Val of PPARα and Pro12Ala of PPAR... DisGeNET Detail
We investigated the association of two common single nucleotide polymorphisms in the PPARA (Leu162Va... DisGeNET Detail
Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala, have recently been... DisGeNET Detail
The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes. DisGeNET Detail
Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala, have recently been... DisGeNET Detail
The association of the Pro12Ala and Pro115Gln PPARgamma2 gene variants with type 2 diabetes mellitus... DisGeNET Detail
The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes. DisGeNET Detail
Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala, have recently been... DisGeNET Detail
The association of the Pro12Ala and Pro115Gln PPARgamma2 gene variants with type 2 diabetes mellitus... DisGeNET Detail
Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala, have recently been... DisGeNET Detail
We have genotyped three single nucleotide polymorphisms associated with type 2 diabetes in a large t... DisGeNET Detail
By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and 44)... DisGeNET Detail
The peroxisome proliferator-activated receptor gamma (PPARG), Pro12Ala and the insulin receptor subs... DisGeNET Detail
By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and 44)... DisGeNET Detail
By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and 44)... DisGeNET Detail
We have genotyped three single nucleotide polymorphisms associated with type 2 diabetes in a large t... DisGeNET Detail
By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and 44)... DisGeNET Detail
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARG; NCBI dbSNP rs1... DisGeNET Detail
Although cross-sectional studies have associated the Pro12Ala polymorphism of PPARG with type 2 diab... DisGeNET Detail
The proline allele at PPARG P12A increases risk for diabetes in persons with impaired glucose tolera... DisGeNET Detail
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obes... DisGeNET Detail
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... DisGeNET Detail
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G... DisGeNET Detail
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... DisGeNET Detail
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNF... DisGeNET Detail
The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) Pro12Ala (P12A) pol... DisGeNET Detail
Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-... DisGeNET Detail
We were unable to replicate in a Caucasian cohort the recent association between PPARγ C161T and UC ... DisGeNET Detail
The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascular risk is controve... DisGeNET Detail
Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associated with nephropath... DisGeNET Detail
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... DisGeNET Detail
Pro12Ala mutation decreases PPARG activity and resistance to NIDDM. DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARgamma) has been a... DisGeNET Detail
The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene has been i... DisGeNET Detail
The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated receptor gamma 2 (PPAR gamm... DisGeNET Detail
Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with insulin resistance a... DisGeNET Detail
The results of the present study demonstrated that possessing the A allele of RAGE -374T/A polymorph... DisGeNET Detail
PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatty liver in middle-ag... DisGeNET Detail
The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascular risk is controve... DisGeNET Detail
We aimed to estimate the association between the common Pro12Ala polymorphism of PPARG2 and risk of ... DisGeNET Detail
Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients... DisGeNET Detail
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... DisGeNET Detail
Pro12Ala polymorphism in human peroxisome proliferator activated receptor gamma is associated with h... DisGeNET Detail
Association of peroxisome proliferator-activated receptor γ Pro12Ala gene polymorphism with type 2 d... DisGeNET Detail
In conclusion, the higher frequency of the C--&gt;T substitution in exon 6 of the PPAR-gamma gene in... DisGeNET Detail
The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated receptor gamma(2) (... DisGeNET Detail
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma 2 gene is suggeste... DisGeNET Detail
PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. DisGeNET Detail
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over... DisGeNET Detail
We hypothesized that interaction between PPARG2 Pro12Ala and variants in the promoter region of HNF4... DisGeNET Detail
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... DisGeNET Detail
A marginally significant increased risk of breast cancer was observed among women homozygous for the... DisGeNET Detail
In contrast, the well-documented associations of peroxisome proliferator-activated receptor gamma P1... DisGeNET Detail
We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobacter pylori infection... DisGeNET Detail
Nominal interactions were observed for sleep duration and PPARG rs1801282, CRY2 rs7943320 and HNF1B ... DisGeNET Detail
Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymor... DisGeNET Detail
Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis. DisGeNET Detail
Our study suggests that the PPARgamma Pro12Ala polymorphism may be a shared risk marker of both IFG ... DisGeNET Detail
The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) Pro12Ala (P12A) pol... DisGeNET Detail
The authors highlight these challenges and biases using an illustrative example: meta-analysis of in... DisGeNET Detail
Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARgamma gene and co... DisGeNET Detail
These results suggest that the PPAR-gamma P12A polymorphism can modulate the association between die... DisGeNET Detail
Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala poly... DisGeNET Detail
The Pro12Ala variant in the PPAR-gamma2 (PPARG) gene was genotyped in 571 non-diabetic relatives of ... DisGeNET Detail
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... DisGeNET Detail
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... DisGeNET Detail
The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated recep... DisGeNET Detail
Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymor... DisGeNET Detail
In this study, we investigated the association of PPAR-γ gene Pro12Ala (rs1801282) and C1431T (rs385... DisGeNET Detail
Nominal interactions were observed for sleep duration and PPARG rs1801282, CRY2 rs7943320 and HNF1B ... DisGeNET Detail
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNF... DisGeNET Detail
Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabete... DisGeNET Detail
Previous studies have sought to associate the Pro12Ala variant of the peroxisome proliferator-activa... DisGeNET Detail
PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. DisGeNET Detail
Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients... DisGeNET Detail
This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protec... DisGeNET Detail
The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. DisGeNET Detail
PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pr... DisGeNET Detail
PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes. DisGeNET Detail
We investigated the synergism between variants at the PPARγ locus (C161T and Pro12Ala polymorphisms)... DisGeNET Detail
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... DisGeNET Detail
Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial c... DisGeNET Detail
We genotyped known single nucleotide polymorphisms (SNPs) in the adiponectin-encoding adipocyte C1q ... DisGeNET Detail
The Pro12Ala polymorphism in the gene encoding PPARγ (PPARγ2 gene) influences the risk for type 2 di... DisGeNET Detail
Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-di... DisGeNET Detail
The PPARgamma Pro12Ala polymorphism has been associated in several studies with a decreased risk of ... DisGeNET Detail
The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastric adenocarcinoma an... DisGeNET Detail
Peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism and its reported rela... DisGeNET Detail
Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and peroxisome proliferator-a... DisGeNET Detail
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with inc... DisGeNET Detail
Our study in healthy Dutch women in combination with the meta-analyses of previous reports does not ... DisGeNET Detail
The association of the C1431T silent mutation and the Pro12Ala missense transversion within the PPAR... DisGeNET Detail
These results suggest that the PPARgamma is a thrifty gene and that the Pro12Ala PPARgamma2 polymorp... DisGeNET Detail
Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T might act as promotion... DisGeNET Detail
To explore the relationship between the genetic polymorphisms of PPARgamma (Pro12Ala, C1431T, and C-... DisGeNET Detail
Although the study was carried out on a sufficiently large sample, the conclusions do not support a ... DisGeNET Detail
PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy. DisGeNET Detail
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... DisGeNET Detail
PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribution, but not metabo... DisGeNET Detail
The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. DisGeNET Detail
Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with polycy... DisGeNET Detail
The P12A variant in the PPARG gene and the E23K polymorphism in KCNJ11 are both known to influence i... DisGeNET Detail
Healthy men, in particular nonsmokers, carrying the Ala12 allele of PPARG rs1801282 polymorphism, ha... DisGeNET Detail
Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a cost effective way for... DisGeNET Detail
Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be associated with decrease... DisGeNET Detail
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is... DisGeNET Detail
We also investigated the possible association between PPARgamma Pro12Ala polymorphism and dementia o... DisGeNET Detail
Association between peroxisome proliferator-activated receptor-γ gene polymorphism (Pro12Ala) and He... DisGeNET Detail
Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral ... DisGeNET Detail
Association between the P12A and c1431t polymorphisms in the peroxisome proliferator activated recep... DisGeNET Detail
Polymorphisms of the peroxisome proliferator-activated receptor-γ (rs1801282) and its coactivator-1 ... DisGeNET Detail
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... DisGeNET Detail
In conclusion, our results confirm that adiponectin concentrations are similar in PCOS and controls ... DisGeNET Detail
Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T might act as promotion... DisGeNET Detail
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in women with pol... DisGeNET Detail
In contrast, the well-documented associations of peroxisome proliferator-activated receptor gamma P1... DisGeNET Detail
Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro12Ala) polymorphism h... DisGeNET Detail
Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala polymorphism with endom... DisGeNET Detail
Four SNPs (rs2167270 of LEP and rs1801282, rs2120825, and rs3856806 of PPARγ) were associated with e... DisGeNET Detail
Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala on ethnic suscep... DisGeNET Detail
The risk associated with the presence of T2D was modified both by IGF2BP2_rs4402960 and PPARγ_rs1801... DisGeNET Detail
The distribution of the Pro(12)Ala PPAR gamma gene polymorphism is equally present in patients with ... DisGeNET Detail
We also investigated the possible association between PPARgamma Pro12Ala polymorphism and dementia o... DisGeNET Detail
Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart dise... DisGeNET Detail
The Pro12Ala polymorphism in the PPAR-gamma gene has been associated with reduced incidence of type ... DisGeNET Detail
Our results suggest that the Pro12Ala polymorphism of the PPARgamma-2 gene promotes peripheral depos... DisGeNET Detail
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is... DisGeNET Detail
Pro12Ala sequence variant of the PPARG gene is associated with postprandial hypertriglyceridemia in ... DisGeNET Detail
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is... DisGeNET Detail
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... DisGeNET Detail
For rectal cancer there was a significant interaction between the Bsm1/polyA polymorphisms (p = 0.00... DisGeNET Detail
Conflicting evidence exists as to whether the Pro12Ala single nucleotide polymorphism of the type 2 ... DisGeNET Detail
We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobacter pylori infection... DisGeNET Detail
Cardiovascular risk factors related to the PPARγ Pro12Ala polymorphism in patients with type 2 diabe... DisGeNET Detail
The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene has been i... DisGeNET Detail
Association of Pro12Ala polymorphism in peroxisome proliferator activated receptor gamma with prolif... DisGeNET Detail
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in first-degree r... DisGeNET Detail
Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 ... DisGeNET Detail
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... DisGeNET Detail
The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabete... DisGeNET Detail
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G... DisGeNET Detail
A population-attributable risk of approximately 50% for the Pro12Pro genotype indicates that testing... DisGeNET Detail
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma 2 gene is suggeste... DisGeNET Detail
We investigated the effects of the common polymorphisms in the peroxisome proliferator-activated rec... DisGeNET Detail
In conclusion, the PPARG Pro12Ala polymorphism might represent a genetic susceptibility factor for p... DisGeNET Detail
Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and ... DisGeNET Detail
This meta-analysis supported the fact that the G allele of PPAR‑γ2 Pro12Ala (rs1801282) modestly aff... DisGeNET Detail
We investigated individual and combined associations of Pro12Ala and His447His polymorphisms of PPAR... DisGeNET Detail
Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 gene mi... DisGeNET Detail
The association between Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma (P... DisGeNET Detail
Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in... DisGeNET Detail
We were able to confirm only one association, that of the common Pro12Ala polymorphism in peroxisome... DisGeNET Detail
Our study in healthy Dutch women in combination with the meta-analyses of previous reports does not ... DisGeNET Detail
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G... DisGeNET Detail
Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro12Ala) polymorphism h... DisGeNET Detail
The influence of the Pro12Ala mutation of the PPAR-gamma receptor gene on metabolic and clinical cha... DisGeNET Detail
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNF... DisGeNET Detail
We examined the relationship between two PPAR-gamma gene polymorphisms, namely the P12A and C161T, a... DisGeNET Detail
Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial c... DisGeNET Detail
Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T might act as promotion... DisGeNET Detail
The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PPARG) gene has been a... DisGeNET Detail
In the present study we have examined the relationship of the Pro(12)Ala polymorphism in the PPARgam... DisGeNET Detail
The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) Pro12Ala (P12A) pol... DisGeNET Detail
The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated recep... DisGeNET Detail
To analyze the relationship between the peroxisome proliferator-activated receptor-gamma (PPARgamma2... DisGeNET Detail
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) has been ... DisGeNET Detail
The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor (PPAR-gamma) gene is inv... DisGeNET Detail
Association between the P12A and c1431t polymorphisms in the peroxisome proliferator activated recep... DisGeNET Detail
The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PPARG) gene has been a... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy. DisGeNET Detail
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... DisGeNET Detail
An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) Pro12Ala polymorphism... DisGeNET Detail
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... DisGeNET Detail
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is... DisGeNET Detail
We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-... DisGeNET Detail
We did not find statistically significant differences with peroxisome proliferator-activated recepto... DisGeNET Detail
Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator-activated recept... DisGeNET Detail
PPARG rs1801282(G) conferred a higher risk of altered insulin (OR=12.31, P=0.003), and HOMA-IR (OR=7... DisGeNET Detail
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) has been ... DisGeNET Detail
The Pro12Ala polymorphism of PPARG was significantly associated with obesity (OR=1.74, 95% CI=1.19-2... DisGeNET Detail
The Pro12Ala polymorphism (rs1801282), a nonsynonymous substitution of peroxisome proliferator-activ... DisGeNET Detail
Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to... DisGeNET Detail
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... DisGeNET Detail
The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene has been i... DisGeNET Detail
We did not find any significant association between three SNPs in the PGC-1alpha gene and T2DM in Hi... DisGeNET Detail
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associated with the suscep... DisGeNET Detail
Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T might act as promotion... DisGeNET Detail
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism could be a risk factor for ga... DisGeNET Detail
Relationship between PPARγ Pro12Ala gene polymorphism and type 2 diabetic nephropathy risk in Asian ... DisGeNET Detail
Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in... DisGeNET Detail
Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients... DisGeNET Detail
Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: ho... DisGeNET Detail
An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) Pro12Ala polymorphism... DisGeNET Detail
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARgamma) has been a... DisGeNET Detail
Larger studies are needed to validate these results, which suggest that the PPARgamma Pro12Ala polym... DisGeNET Detail
The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated receptor gamma 2 (PPAR gamm... DisGeNET Detail
PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes. DisGeNET Detail
There was a significant interaction between the -200A&gt;C IGFBP3 polymorphism and the Pro12Ala PPAR... DisGeNET Detail
PPARγ Pro12Ala interacts with fat intake for obesity and weight loss in a behavioural treatment base... DisGeNET Detail
The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabete... DisGeNET Detail
The aim of the present study was to investigate the relation between TG-related parameters considere... DisGeNET Detail
We investigated a possible association of PPARg2 Pro12Ala polymorphism with obesity and myocardial i... DisGeNET Detail
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over... DisGeNET Detail
Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator-activated recept... DisGeNET Detail
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... DisGeNET Detail
In conclusion, the higher frequency of the C--&gt;T substitution in exon 6 of the PPAR-gamma gene in... DisGeNET Detail
In contrast, the well-documented associations of peroxisome proliferator-activated receptor gamma P1... DisGeNET Detail
Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro12Ala) polymorphism h... DisGeNET Detail
Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabete... DisGeNET Detail
Four SNPs (rs2167270 of LEP and rs1801282, rs2120825, and rs3856806 of PPARγ) were associated with e... DisGeNET Detail
In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma polymorphism and bo... DisGeNET Detail
Association between peroxisome proliferator-activated receptor-γ gene polymorphism (Pro12Ala) and He... DisGeNET Detail
This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protec... DisGeNET Detail
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... DisGeNET Detail
The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated receptor gamma(2) (... DisGeNET Detail
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... DisGeNET Detail
We hypothesized that interaction between PPARG2 Pro12Ala and variants in the promoter region of HNF4... DisGeNET Detail
Association of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala polymorphism with advance... DisGeNET Detail
Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has be... DisGeNET Detail
Our study indicates that PPARG rs1801282 may significantly predict overweight, BMI, and total choles... DisGeNET Detail
The Pro12Ala PPARG sequence variant together with a non-E3/E3 APOE genotype is associated with a hig... DisGeNET Detail
The Pro12Ala and the 4a/b polymorphisms of the peroxisome proliferator-activated receptor gamma (PPA... DisGeNET Detail
There appears to be certain genes which predispose Indians to diabetes while other genes (for exampl... DisGeNET Detail
The Pro12Ala polymorphism of PPARG was significantly associated with obesity (OR=1.74, 95% CI=1.19-2... DisGeNET Detail
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... DisGeNET Detail
Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala on ethnic suscep... DisGeNET Detail
We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-... DisGeNET Detail
The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene... DisGeNET Detail
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... DisGeNET Detail
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in in... DisGeNET Detail
Our findings suggest that Pro12Ala PPAR-gamma gene polymorphism may be protective against IR and mig... DisGeNET Detail
This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protec... DisGeNET Detail
Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mell... DisGeNET Detail
The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated receptor gamma 2 (PPAR gamm... DisGeNET Detail
The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is associated with a lowe... DisGeNET Detail
In this study, we evaluated the association between colorectal cancer and specific tumor mutations a... DisGeNET Detail
The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated recep... DisGeNET Detail
For the Pro12Ala polymorphism in PPARγ, although patients with the Pro/Ala genotype (8.8%) had a hig... DisGeNET Detail
The purpose of this study was to examine whether a Proline (Pro)-to-Alanine (Ala) exchange at codon ... DisGeNET Detail
To investigate the influence of the peroxisome proliferator activated receptor gamma (PPAR-γ) Pro12A... DisGeNET Detail
Our study suggests that the PPARgamma Pro12Ala polymorphism may be a shared risk marker of both IFG ... DisGeNET Detail
In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegregate with lipodystro... DisGeNET Detail
Here, we investigated the expression of APM1 in adipose tissue and studied the relationship between ... DisGeNET Detail
Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart dise... DisGeNET Detail
Pro12Ala, a missense mutation in exon 2 of PPARG, reduces transcriptional activity of PPARgamma2 and... DisGeNET Detail
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) gene and ... DisGeNET Detail
Quantitative assessment of the influence of PPARG P12A polymorphism on gestational diabetes mellitus... DisGeNET Detail
The present study demonstrates that the AA genotype of the Gly482Ser polymorphism in the PPARGC1 gen... DisGeNET Detail
The goal of this study was to examine whether the Pro12Ala polymorphism of peroxisome proliferator-a... DisGeNET Detail
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism could be a risk factor for ga... DisGeNET Detail
The Pro12Ala polymorphism of the gene for peroxisome proliferator activated receptor-gamma is associ... DisGeNET Detail
Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a cost effective way for... DisGeNET Detail
There appears to be certain genes which predispose Indians to diabetes while other genes (for exampl... DisGeNET Detail
PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribution, but not metabo... DisGeNET Detail
No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer susceptibility. DisGeNET Detail
PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. DisGeNET Detail
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G... DisGeNET Detail
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... DisGeNET Detail
Our meta-analysis supports that the ApoE ε2 allele and ACACB rs2268388 C&gt;T might act as promotion... DisGeNET Detail
Lack of genetic associations between PPAR-γ gene rs1801282 polymorphism and Alzheimer's disease in g... DisGeNET Detail
The Pro12Ala polymorphism of the PPARgamma gene is associated with increased insulin sensitivity and... DisGeNET Detail
To explore the way that population description is used to replicate and/or extend previously reporte... DisGeNET Detail
A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associate... DisGeNET Detail
Common polymorphisms of the peroxisome proliferator-activated receptor-gamma (Pro12Ala) and peroxiso... DisGeNET Detail
This meta-analysis supported the fact that the G allele of PPAR‑γ2 Pro12Ala (rs1801282) modestly aff... DisGeNET Detail
The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastric adenocarcinoma an... DisGeNET Detail
Four of the nine SNPs revealed a significant association with T2D; PPARG2 (Pro12Ala) [odds ratio (OR... DisGeNET Detail
The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated recep... DisGeNET Detail
The common Pro12Ala polymorphism in PPARgamma is associated with lower diastolic blood pressure in m... DisGeNET Detail
Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients... DisGeNET Detail
No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery disease in Korean su... DisGeNET Detail
PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes. DisGeNET Detail
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 di... DisGeNET Detail
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... DisGeNET Detail
The common Pro12Ala polymorphism in peroxisome proliferator-activated receptor-γ (PPAR-γ) gene was c... DisGeNET Detail
The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator-Activated Receptor ... DisGeNET Detail
Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotypes with susceptibilit... DisGeNET Detail
Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and peroxisome proliferator-a... DisGeNET Detail
In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma polymorphism and bo... DisGeNET Detail
Associations between C1431T and Pro12Ala variants of PPARγ gene and their haplotypes with susceptibi... DisGeNET Detail
The risk associated with the presence of T2D was modified both by IGF2BP2_rs4402960 and PPARγ_rs1801... DisGeNET Detail
In a large sample of the Caucasians the rs8192673 of the PGC-1α gene and the rs1801282 of the PPAR-γ... DisGeNET Detail
Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 gene mi... DisGeNET Detail
Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala variant on obesity, gluc... DisGeNET Detail
A meta-analysis on the association between PPAR-γ Pro12Ala polymorphism and polycystic ovary syndrom... DisGeNET Detail
Association between the Pro12Ala polymorphism of PPAR-γ gene and the non-alcoholic fatty liver disea... DisGeNET Detail
Evidence for interaction between PPARG Pro12Ala and PPARGC1A Gly482Ser polymorphisms in determining ... DisGeNET Detail
There was a significant interaction between the -200A&gt;C IGFBP3 polymorphism and the Pro12Ala PPAR... DisGeNET Detail
Polymorphism of peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala in the Iranian populat... DisGeNET Detail
We investigated the relationship between 2 common PPARG polymorphisms, namely P12A and c.1431C&gt;T,... DisGeNET Detail
The peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala polymorphism has been associ... DisGeNET Detail
Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-... DisGeNET Detail
The Pro12Ala PPARgamma polymorphism does not seem to be associated with BMI or metabolic syndrome pa... DisGeNET Detail
The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene has been i... DisGeNET Detail
Association between the peroxisome proliferator-activated receptor gamma Pro12Ala variant and haplot... DisGeNET Detail
In this study, we evaluated the association between colorectal cancer and specific tumor mutations a... DisGeNET Detail
Our findings suggest that Pro12Ala PPAR-gamma gene polymorphism may be protective against IR and mig... DisGeNET Detail
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma 2 gene is suggeste... DisGeNET Detail
These results suggest that in the Taiwanese, the Pro12Ala PPARgamma2 gene variant may contribute to ... DisGeNET Detail
Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart dise... DisGeNET Detail
The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is associated with a lowe... DisGeNET Detail
We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-... DisGeNET Detail
Polymorphisms of the peroxisome proliferator-activated receptor-γ (rs1801282) and its coactivator-1 ... DisGeNET Detail
Four of the nine SNPs revealed a significant association with T2D; PPARG2 (Pro12Ala) [odds ratio (OR... DisGeNET Detail
Lack of an association between peroxisome proliferator-activated receptor-gamma gene Pro12Ala polymo... DisGeNET Detail
Evidence for interaction between PPARG Pro12Ala and PPARGC1A Gly482Ser polymorphisms in determining ... DisGeNET Detail
This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protec... DisGeNET Detail
The alanine allele of P12A polymorphism in PPARG gene in a few studies has been associated with a re... DisGeNET Detail
Nominal interactions were observed for sleep duration and PPARG rs1801282, CRY2 rs7943320 and HNF1B ... DisGeNET Detail
The aim of this study was to clarify whether common single nucleotide polymorphisms (SNPs) of the Pe... DisGeNET Detail
Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pedi... DisGeNET Detail
The data suggest a contribution of the Pro12Ala polymorphism of PPARgamma to genetic susceptibility ... DisGeNET Detail
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over... DisGeNET Detail
Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with insulin resistance a... DisGeNET Detail
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... DisGeNET Detail
There was a significant interaction between the -200A&gt;C IGFBP3 polymorphism and the Pro12Ala PPAR... DisGeNET Detail
The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. DisGeNET Detail
Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: ho... DisGeNET Detail
The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated receptor γ (PPARγ) have be... DisGeNET Detail
We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-... DisGeNET Detail
Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabetes mellitus on HbA1c ... DisGeNET Detail
For rectal cancer there was a significant interaction between the Bsm1/polyA polymorphisms (p = 0.00... DisGeNET Detail
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... DisGeNET Detail
Is it time to conduct a hypothesis-driven large-scale exercise training intervention trial based on ... DisGeNET Detail
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with inc... DisGeNET Detail
The association of non-synonymous substitution polymorphism rs1801282 (c.34C&gt;G, p.Pro12Ala) in ex... DisGeNET Detail
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... DisGeNET Detail
A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associate... DisGeNET Detail
PPARG rs1801282(G) conferred a higher risk of altered insulin (OR=12.31, P=0.003), and HOMA-IR (OR=7... DisGeNET Detail
The peroxisome proliferator-activated receptor gamma 2 Pro12Ala mutation is associated with early on... DisGeNET Detail
PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. DisGeNET Detail
Pro12Ala sequence variant of the PPARG gene is associated with postprandial hypertriglyceridemia in ... DisGeNET Detail
Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associated with nephropath... DisGeNET Detail
Nevertheless, prospectively designed cohort studies are needed to further investigate gene-gene and ... DisGeNET Detail
These observations suggest that Pro12Ala (rs1801282), a coding variant in the PPARG gene, is associa... DisGeNET Detail
The proline allele at PPARG P12A increases risk for diabetes in persons with impaired glucose tolera... DisGeNET Detail
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... DisGeNET Detail
The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator-Activated Receptor ... DisGeNET Detail
Hence, our aim was to develop a low-cost method for the validation of PPARG (Pro12Ala, CCA&gt;GCA) S... DisGeNET Detail
In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotype have greater odds ... DisGeNET Detail
Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral ... DisGeNET Detail
No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery disease in Korean su... DisGeNET Detail
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... DisGeNET Detail
The frequencies of 2 common polymorphisms of the PPARgamma gene, Pro12Ala single nucleotide polymorp... DisGeNET Detail
The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastric adenocarcinoma an... DisGeNET Detail
Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARgamma gene and co... DisGeNET Detail
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obes... DisGeNET Detail
The aim was to investigate if the polymorphism PPARgamma2 Pro12Ala, which encodes a less efficient t... DisGeNET Detail
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... DisGeNET Detail
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma (PPARG) gene in re... DisGeNET Detail
Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits... DisGeNET Detail
Compared with first-degree relatives of PCOS subjects with the Pro12Pro polymorphism of PPAR-gamma, ... DisGeNET Detail
Together, these results showed that PPARG Pro12Ala and PPARGC1A Gly482Ser variants are associated, a... DisGeNET Detail
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is... DisGeNET Detail
The data suggest a contribution of the Pro12Ala polymorphism of PPARgamma to genetic susceptibility ... DisGeNET Detail
In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegregate with lipodystro... DisGeNET Detail
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associated with the suscep... DisGeNET Detail
The Pro12Ala polymorphism of the gene for peroxisome proliferator activated receptor-gamma is associ... DisGeNET Detail
The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated receptor gamma(2) (... DisGeNET Detail
Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala poly... DisGeNET Detail
We conclude that PPARg2 Pro12Ala polymorphisms are associated with increased risk for myocardial inf... DisGeNET Detail
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) has been ... DisGeNET Detail
The authors highlight these challenges and biases using an illustrative example: meta-analysis of in... DisGeNET Detail
No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery disease in Korean su... DisGeNET Detail
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) gene and ... DisGeNET Detail
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNF... DisGeNET Detail
Prevalence of the Pro12Ala missense mutation in the PPARG2 gene in Kuwaiti patients with primary kne... DisGeNET Detail
Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial c... DisGeNET Detail
We suggest that Pro12Ala polymorphism of the PPAR-gamma gene may be a modifier of insulin resistance... DisGeNET Detail
There was a significant interaction between the -200A&gt;C IGFBP3 polymorphism and the Pro12Ala PPAR... DisGeNET Detail
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obes... DisGeNET Detail
PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pr... DisGeNET Detail
The present study demonstrates that the AA genotype of the Gly482Ser polymorphism in the PPARGC1 gen... DisGeNET Detail
Association between the Pro12Ala polymorphism of PPAR-γ gene and the polycystic ovary syndrome: a me... DisGeNET Detail
Our objective was to search for differences in genotypes of peroxisome proliferator-activated recept... DisGeNET Detail
A marginally significant increased risk of breast cancer was observed among women homozygous for the... DisGeNET Detail
The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. DisGeNET Detail
In the group of participants with PPARγ Pro12Ala or Ala12Ala genotypes, those with the LPL Pvu (-/+)... DisGeNET Detail
The presence of PPARγ2 rs1801282 G allele (Ala variant) was associated with increased odds for achie... DisGeNET Detail
Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Ch... DisGeNET Detail
Association between the peroxisome proliferator-activated receptor gamma Pro12Ala variant and haplot... DisGeNET Detail
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... DisGeNET Detail
PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes. DisGeNET Detail
This study has shown that both Pro12Ala and His447His polymorphisms of PPAR-gamma are associated wit... DisGeNET Detail
The single nucleotide polymorphisms (SNPs) of the above genes, such as GNB3-C825T, ADRB3-Trp64Arg, U... DisGeNET Detail
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), I... DisGeNET Detail
Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be associated with decrease... DisGeNET Detail
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... DisGeNET Detail
We examined the relationship between PPARG2 P12A and CHD risk in women (Nurses' Health Study) and me... DisGeNET Detail
In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma polymorphism and bo... DisGeNET Detail
We conclude that P12A and C161T polymorphisms of the PPAR-gamma gene are important predictors of car... DisGeNET Detail
The protective role of the Ala allele in the Pro12Ala polymorphism of PPARγ on type 2 diabetes has b... DisGeNET Detail
Two PPARg common polymorphisms, Pro12Ala and 161C&gt;T, have been found to be associated with cardio... DisGeNET Detail
In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma polymorphism and bo... DisGeNET Detail
The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated receptor γ (PPARγ) have be... DisGeNET Detail
Association between the Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma 2 ... DisGeNET Detail
The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated receptor gamma 2 (PPAR gamm... DisGeNET Detail
In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotype have greater odds ... DisGeNET Detail
Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has be... DisGeNET Detail
Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ1... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... DisGeNET Detail
Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ1... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ1... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ1... DisGeNET Detail
Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ1... DisGeNET Detail
Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... DisGeNET Detail
Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ1... DisGeNET Detail
13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP... DisGeNET Detail
Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ1... DisGeNET Detail
Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ1... DisGeNET Detail
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we ... DisGeNET Detail
A total of 792 patients with T2DM were enrolled and categorized into two groups: (1) the DR group co... DisGeNET Detail
A total of 792 patients with T2DM were enrolled and categorized into two groups: (1) the DR group co... DisGeNET Detail
A total of 792 patients with T2DM were enrolled and categorized into two groups: (1) the DR group co... DisGeNET Detail
A total of 792 patients with T2DM were enrolled and categorized into two groups: (1) the DR group co... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs1801282 dbSNP
Genome
hg38
Position
chr3:12,351,626-12,351,626
Variant Type
snv
Reference Allele
C
Alternative Allele
G
Filtering Status (HGVD)
PASS
# of samples (HGVD)
1199
Mean of sample read depth (HGVD)
43.00
Standard deviation of sample read depth (HGVD)
20.78
Number of reference allele (HGVD)
2330
Number of alternative allele (HGVD)
68
Allele Frequency (HGVD)
0.02835696413678065
Gene Symbol (HGVD)
PPARG
ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
PASS
Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
rs1801282
Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
0.03
Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
502
Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
16760
East Asian Chromosome Counts (ExAC)
8598
East Asian Allele Counts (ExAC)
372
East Asian Heterozygous Counts (ExAC)
362
East Asian Homozygous Counts (ExAC)
5
East Asian Allele Frequency (ExAC)
0.04326587578506629
Chromosome Counts in All Race (ExAC)
121246
Allele Counts in All Race (ExAC)
13354
Heterozygous Counts in All Race (ExAC)
11646
Homozygous Counts in All Race (ExAC)
854
Allele Frequency in All Race (ExAC)
0.11013971594939215
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