chr3:12421238:C>G Detail (hg19) (PPARG)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr3:12,421,238-12,421,238 |
hg38 | chr3:12,379,739-12,379,739 View the variant detail on this assembly version. |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_015869.4:c.118C>G | NP_056953.2:p.Pro40Ala |
NM_138712.3:c.28C>G | NP_619726.2:p.Pro10Ala | |
NM_005037.5:c.28C>G | NP_005028.4:p.Pro10Ala |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
---|---|---|---|---|---|
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2007-06-01 | no assertion criteria provided | Diabetes mellitus, noninsulin-dependent, modifier of |
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Detail |
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2007-06-01 | no assertion criteria provided | Obesity, modifier of |
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Detail |
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2007-06-01 | no assertion criteria provided | Body mass index, modifier of |
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Detail |
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2007-06-01 | no assertion criteria provided | Intimal medial thickness of internal carotid artery, modifier of |
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Detail |
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.439 | obesity | Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP... | BeFree | 15972940 | Detail |
0.641 | obesity | Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP... | BeFree | 15972940 | Detail |
0.002 | obesity | Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP... | BeFree | 15972940 | Detail |
0.329 | Diabetes Mellitus, Non-Insulin-Dependent | In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... | BeFree | 18498634 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... | BeFree | 18498634 | Detail |
0.614 | Diabetes Mellitus, Non-Insulin-Dependent | In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... | BeFree | 18498634 | Detail |
0.330 | Diabetes Mellitus, Non-Insulin-Dependent | In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... | BeFree | 18498634 | Detail |
0.340 | Diabetes Mellitus, Non-Insulin-Dependent | In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... | BeFree | 18498634 | Detail |
0.322 | Diabetes Mellitus, Non-Insulin-Dependent | In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR =... | BeFree | 18498634 | Detail |
0.440 | obesity | Seven variants displaying conflicting results in previous reports and supposedly... | BeFree | 21233811 | Detail |
0.439 | obesity | Seven variants displaying conflicting results in previous reports and supposedly... | BeFree | 21233811 | Detail |
0.147 | obesity | Seven variants displaying conflicting results in previous reports and supposedly... | BeFree | 21233811 | Detail |
0.034 | obesity | Seven variants displaying conflicting results in previous reports and supposedly... | BeFree | 21233811 | Detail |
0.039 | colorectal cancer | We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), ... | BeFree | 16937502 | Detail |
0.007 | colorectal carcinoma | We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), ... | BeFree | 16937502 | Detail |
0.037 | colorectal cancer | We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), ... | BeFree | 16937502 | Detail |
0.011 | colorectal carcinoma | We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), ... | BeFree | 16937502 | Detail |
0.026 | colorectal cancer | We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), ... | BeFree | 16937502 | Detail |
0.011 | colorectal carcinoma | We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), ... | BeFree | 16937502 | Detail |
0.001 | Metabolic syndrome X | The frequency distribution of rare alleles for PPARα (L162V) and PPARγ (P12A and... | BeFree | 21877956 | Detail |
0.003 | Non-alcoholic Fatty Liver Disease | The objective of this study was to analyze the polymorphisms Leu162Val of PPARα ... | BeFree | 23891824 | Detail |
0.007 | HIV Infections | The frequency distribution of rare alleles for PPARα (L162V) and PPARγ (P12A and... | BeFree | 21877956 | Detail |
0.124 | Non-alcoholic Fatty Liver Disease | The objective of this study was to analyze the polymorphisms Leu162Val of PPARα ... | BeFree | 23891824 | Detail |
0.003 | multiple sclerosis | We investigated the association of two common single nucleotide polymorphisms in... | BeFree | 18977277 | Detail |
0.163 | diabetes mellitus | Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala... | BeFree | 10757637 | Detail |
0.439 | obesity | The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabe... | BeFree | 10757637 | Detail |
0.008 | Diabetes | Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala... | BeFree | 10757637 | Detail |
0.017 | Diabetes | The association of the Pro12Ala and Pro115Gln PPARgamma2 gene variants with type... | BeFree | 11079814 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabe... | BeFree | 10757637 | Detail |
0.017 | Diabetes | Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala... | BeFree | 10757637 | Detail |
0.163 | diabetes mellitus | The association of the Pro12Ala and Pro115Gln PPARgamma2 gene variants with type... | BeFree | 11079814 | Detail |
0.016 | diabetes mellitus | Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala... | BeFree | 10757637 | Detail |
0.466 | Diabetes Mellitus, Non-Insulin-Dependent | We have genotyped three single nucleotide polymorphisms associated with type 2 d... | BeFree | 14988278 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | By using a Cox proportional hazard model, common variants in the PPARG (P12A), C... | BeFree | 17570749 | Detail |
0.401 | Diabetes Mellitus, Non-Insulin-Dependent | The peroxisome proliferator-activated receptor gamma (PPARG), Pro12Ala and the i... | BeFree | 24447396 | Detail |
0.274 | Diabetes Mellitus, Non-Insulin-Dependent | By using a Cox proportional hazard model, common variants in the PPARG (P12A), C... | BeFree | 17570749 | Detail |
0.466 | Diabetes Mellitus, Non-Insulin-Dependent | By using a Cox proportional hazard model, common variants in the PPARG (P12A), C... | BeFree | 17570749 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | We have genotyped three single nucleotide polymorphisms associated with type 2 d... | BeFree | 14988278 | Detail |
0.627 | Diabetes Mellitus, Non-Insulin-Dependent | By using a Cox proportional hazard model, common variants in the PPARG (P12A), C... | BeFree | 17570749 | Detail |
0.439 | obesity | The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... | BeFree | 18280041 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Although cross-sectional studies have associated the Pro12Ala polymorphism of PP... | BeFree | 16567542 | Detail |
0.012 | Impaired glucose tolerance | The proline allele at PPARG P12A increases risk for diabetes in persons with imp... | BeFree | 17213274 | Detail |
0.163 | diabetes mellitus | The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gen... | BeFree | 17898990 | Detail |
0.002 | Diabetes Mellitus, Non-Insulin-Dependent | Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... | BeFree | 16804087 | Detail |
0.003 | gestational diabetes | The other polymorphisms studied were not significantly associated with gestation... | BeFree | 17342473 | Detail |
0.163 | diabetes mellitus | Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... | BeFree | 17213274 | Detail |
0.007 | Malignant neoplasm of urinary bladder | Using the TaqMan method, we genotyped single nucleotide polymorphisms in interle... | BeFree | 16110031 | Detail |
0.003 | diabetes mellitus | There was no convincing association between any polymorphism of PPARα and PPARγ ... | BeFree | 21877956 | Detail |
0.447 | Diabetes Mellitus, Non-Insulin-Dependent | In fact, we evaluated the effect of seven polymorphisms in the following genes-P... | BeFree | 23249316 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2)... | BeFree | 15562396 | Detail |
0.440 | obesity | Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activ... | BeFree | 19733160 | Detail |
0.013 | ulcerative colitis | We were unable to replicate in a Caucasian cohort the recent association between... | BeFree | 23256116 | Detail |
0.017 | Diabetes | The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascu... | BeFree | 22017455 | Detail |
0.004 | Kidney Diseases | Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associ... | BeFree | 17493550 | Detail |
0.008 | Diabetes | Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... | BeFree | 16567542 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Pro12Ala mutation decreases PPARG activity and resistance to NIDDM. | BeFree | 22937051 | Detail |
0.220 | gestational diabetes | The other polymorphisms studied were not significantly associated with gestation... | BeFree | 17342473 | Detail |
<0.001 | gestational diabetes | The other polymorphisms studied were not significantly associated with gestation... | BeFree | 17342473 | Detail |
0.439 | obesity | The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... | BeFree | 19766907 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARga... | BeFree | 16253648 | Detail |
0.004 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated recepto... | BeFree | 14981210 | Detail |
0.343 | obesity | Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with ... | BeFree | 17624182 | Detail |
0.020 | coronary artery disease | The results of the present study demonstrated that possessing the A allele of RA... | BeFree | 21861709 | Detail |
0.003 | Non-alcoholic Fatty Liver Disease | PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatt... | BeFree | 21939732 | Detail |
0.163 | diabetes mellitus | The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascu... | BeFree | 22017455 | Detail |
0.371 | Diabetes Mellitus, Insulin-Dependent | We aimed to estimate the association between the common Pro12Ala polymorphism of... | BeFree | 18211635 | Detail |
0.001 | Coronary heart disease | Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary he... | BeFree | 21833536 | Detail |
<0.001 | diabetes mellitus | Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... | BeFree | 16567542 | Detail |
0.007 | Hyperlipidemia | Pro12Ala polymorphism in human peroxisome proliferator activated receptor gamma ... | BeFree | 21669017 | Detail |
0.102 | Diabetic Nephropathy | Association of peroxisome proliferator-activated receptor γ Pro12Ala gene polymo... | BeFree | 24329532 | Detail |
0.004 | Ovarian Diseases | In conclusion, the higher frequency of the C-->T substitution in exon 6 of th... | BeFree | 14671186 | Detail |
<0.001 | Dyslipidemias | The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated... | BeFree | 11158005 | Detail |
0.102 | Diabetic Nephropathy | The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamm... | BeFree | 18467141 | Detail |
0.003 | Diabetes | PPARG P12A (rs1801282) was not significantly associated with diabetes or related... | BeFree | 17903298 | Detail |
0.003 | hyperglycemia | The PPARG Pro12Ala polymorphism is associated with a decreased risk of developin... | BeFree | 16567542 | Detail |
0.007 | gestational diabetes | We hypothesized that interaction between PPARG2 Pro12Ala and variants in the pro... | BeFree | 18162503 | Detail |
0.008 | Diabetes | There was no convincing association between any polymorphism of PPARα and PPARγ ... | BeFree | 21877956 | Detail |
0.023 | Malignant neoplasm of breast | A marginally significant increased risk of breast cancer was observed among wome... | BeFree | 17348446 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | In contrast, the well-documented associations of peroxisome proliferator-activat... | BeFree | 15561965 | Detail |
0.004 | Malignant neoplasm of stomach | We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobac... | BeFree | 18372284 | Detail |
0.062 | polycystic ovary syndrome | Insulin resistance is attenuated in women with polycystic ovary syndrome with th... | BeFree | 11836319 | Detail |
0.003 | multiple sclerosis | Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of mu... | BeFree | 18977277 | Detail |
0.005 | stomach carcinoma | Our study suggests that the PPARgamma Pro12Ala polymorphism may be a shared risk... | BeFree | 17763950 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2)... | BeFree | 15562396 | Detail |
0.163 | diabetes mellitus | The authors highlight these challenges and biases using an illustrative example:... | BeFree | 20406760 | Detail |
0.011 | colorectal carcinoma | Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the P... | BeFree | 16965392 | Detail |
0.145 | Metabolic syndrome X | These results suggest that the PPAR-gamma P12A polymorphism can modulate the ass... | BeFree | 12630956 | Detail |
0.003 | Arthritis, Psoriatic | Meta-analysis of associations between the peroxisome proliferator-activated rece... | BeFree | 24697566 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala variant in the PPAR-gamma2 (PPARG) gene was genotyped in 571 non-di... | BeFree | 17700648 | Detail |
0.145 | Metabolic syndrome X | There was no convincing association between any polymorphism of PPARα and PPARγ ... | BeFree | 21877956 | Detail |
0.017 | Diabetes | Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... | BeFree | 16567542 | Detail |
0.162 | polycystic ovary syndrome | Insulin resistance is attenuated in women with polycystic ovary syndrome with th... | BeFree | 11836319 | Detail |
0.127 | Obesity, Morbid | In this study, we investigated the association of PPAR-γ gene Pro12Ala (rs180128... | BeFree | 22410809 | Detail |
0.614 | Diabetes Mellitus, Non-Insulin-Dependent | In fact, we evaluated the effect of seven polymorphisms in the following genes-P... | BeFree | 23249316 | Detail |
0.163 | diabetes mellitus | Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasm... | BeFree | 14729856 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Previous studies have sought to associate the Pro12Ala variant of the peroxisome... | BeFree | 17985660 | Detail |
0.017 | Diabetes | PPARG P12A (rs1801282) was not significantly associated with diabetes or related... | BeFree | 17903298 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary he... | BeFree | 21833536 | Detail |
0.011 | colorectal carcinoma | This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphi... | BeFree | 20596649 | Detail |
0.010 | Coronary Arteriosclerosis | The meta-analysis of the association of PPARG P12A, C161T polymorphism and coron... | BeFree | 22987045 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in As... | BeFree | 19846176 | Detail |
<0.001 | Impaired cognition | PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diab... | BeFree | 18280041 | Detail |
0.145 | Metabolic syndrome X | We investigated the synergism between variants at the PPARγ locus (C161T and Pro... | BeFree | 24243083 | Detail |
0.003 | Diabetes | Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... | BeFree | 17213274 | Detail |
<0.001 | endometrial carcinoma | Opposite association of two PPARG variants with cancer: overrepresentation of H4... | BeFree | 11511919 | Detail |
0.305 | obesity | We genotyped known single nucleotide polymorphisms (SNPs) in the adiponectin-enc... | BeFree | 15830179 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala polymorphism in the gene encoding PPARγ (PPARγ2 gene) influences th... | BeFree | 21206011 | Detail |
0.003 | prediabetes syndrome | Association of Pro12Ala polymorphism in peroxisome proliferator-activated recept... | BeFree | 17065690 | Detail |
0.439 | obesity | The PPARgamma Pro12Ala polymorphism has been associated in several studies with ... | BeFree | 17408525 | Detail |
0.005 | Peptic Ulcer | The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastr... | BeFree | 18372284 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism a... | BeFree | 22413765 | Detail |
0.005 | sarcoidosis | Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and perox... | BeFree | 19070258 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is... | BeFree | 12218380 | Detail |
0.026 | Coronary heart disease | Our study in healthy Dutch women in combination with the meta-analyses of previo... | BeFree | 18561518 | Detail |
0.439 | obesity | The association of the C1431T silent mutation and the Pro12Ala missense transver... | BeFree | 18250615 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | These results suggest that the PPARgamma is a thrifty gene and that the Pro12Ala... | BeFree | 10777704 | Detail |
0.258 | Hypertensive disease | To explore the relationship between the genetic polymorphisms of PPARgamma (Pro1... | BeFree | 19651920 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Although the study was carried out on a sufficiently large sample, the conclusio... | BeFree | 10389855 | Detail |
0.007 | HIV Infections | PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related li... | BeFree | 19534662 | Detail |
0.002 | Impaired glucose tolerance | Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... | BeFree | 16804087 | Detail |
0.145 | Metabolic syndrome X | PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribu... | BeFree | 22168210 | Detail |
<0.001 | Coronary Arteriosclerosis | The meta-analysis of the association of PPARG P12A, C161T polymorphism and coron... | BeFree | 22987045 | Detail |
0.062 | polycystic ovary syndrome | Association of Pro12Ala polymorphism in peroxisome proliferator-activated recept... | BeFree | 22729915 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | The P12A variant in the PPARG gene and the E23K polymorphism in KCNJ11 are both ... | BeFree | 17994213 | Detail |
<0.001 | Diabetes Mellitus, Non-Insulin-Dependent | Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a co... | BeFree | 25063576 | Detail |
0.008 | diabetic retinopathy | Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be asso... | BeFree | 18077048 | Detail |
0.374 | Diabetes Mellitus, Non-Insulin-Dependent | Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (... | BeFree | 17439324 | Detail |
<0.001 | Presenile dementia | We also investigated the possible association between PPARgamma Pro12Ala polymor... | BeFree | 21970714 | Detail |
0.001 | Helicobacter pylori infection | Association between peroxisome proliferator-activated receptor-γ gene polymorphi... | BeFree | 20568969 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mell... | BeFree | 16920849 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Association between the P12A and c1431t polymorphisms in the peroxisome prolifer... | BeFree | 11409297 | Detail |
0.017 | Diabetes | The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... | BeFree | 17493550 | Detail |
0.004 | Ovarian Diseases | In conclusion, our results confirm that adiponectin concentrations are similar i... | BeFree | 15472214 | Detail |
0.062 | polycystic ovary syndrome | Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma ge... | BeFree | 16785159 | Detail |
0.466 | Diabetes Mellitus, Non-Insulin-Dependent | In contrast, the well-documented associations of peroxisome proliferator-activat... | BeFree | 15561965 | Detail |
0.094 | arteriosclerosis | Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro1... | BeFree | 25159899 | Detail |
0.011 | endometriosis | Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala pol... | BeFree | 15136115 | Detail |
0.017 | Diabetes | Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12... | BeFree | 17941898 | Detail |
0.003 | Graves Disease | The distribution of the Pro(12)Ala PPAR gamma gene polymorphism is equally prese... | BeFree | 18624999 | Detail |
0.005 | dementia | We also investigated the possible association between PPARgamma Pro12Ala polymor... | BeFree | 21970714 | Detail |
0.026 | Coronary heart disease | Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident... | BeFree | 22515931 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala polymorphism in the PPAR-gamma gene has been associated with reduce... | BeFree | 18639367 | Detail |
0.010 | hyperinsulinism | Our results suggest that the Pro12Ala polymorphism of the PPARgamma-2 gene promo... | BeFree | 12370112 | Detail |
0.026 | Coronary heart disease | The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamm... | BeFree | 23300871 | Detail |
<0.001 | Pyruvate dehydrogenase E3-binding protein deficiency | Pro12Ala sequence variant of the PPARG gene is associated with postprandial hype... | BeFree | 16916989 | Detail |
0.020 | coronary artery disease | The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamm... | BeFree | 23300871 | Detail |
0.163 | diabetes mellitus | The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... | BeFree | 17493550 | Detail |
0.002 | Rectal Carcinoma | For rectal cancer there was a significant interaction between the Bsm1/polyA pol... | BeFree | 16489531 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Conflicting evidence exists as to whether the Pro12Ala single nucleotide polymor... | BeFree | 18466209 | Detail |
0.005 | stomach carcinoma | We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobac... | BeFree | 18372284 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Cardiovascular risk factors related to the PPARγ Pro12Ala polymorphism in patien... | BeFree | 22017455 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARga... | BeFree | 16253648 | Detail |
<0.001 | proliferative diabetic retinopathy | Association of Pro12Ala polymorphism in peroxisome proliferator activated recept... | BeFree | 23559865 | Detail |
0.062 | polycystic ovary syndrome | Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma ge... | BeFree | 16316841 | Detail |
0.439 | obesity | Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated rec... | BeFree | 12679463 | Detail |
<0.001 | Diabetic Nephropathy | The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... | BeFree | 17493550 | Detail |
0.163 | diabetes mellitus | The role of the Pro12Ala polymorphism in peroxisome proliferator-activated recep... | BeFree | 17563457 | Detail |
0.023 | Malignant neoplasm of urinary bladder | Using the TaqMan method, we genotyped single nucleotide polymorphisms in interle... | BeFree | 16110031 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | A population-attributable risk of approximately 50% for the Pro12Pro genotype in... | BeFree | 16822823 | Detail |
0.021 | Cardiovascular Diseases | The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamm... | BeFree | 18467141 | Detail |
0.287 | Diabetes Mellitus, Non-Insulin-Dependent | We investigated the effects of the common polymorphisms in the peroxisome prolif... | BeFree | 20045142 | Detail |
0.126 | Metabolic Diseases | In conclusion, the PPARG Pro12Ala polymorphism might represent a genetic suscept... | BeFree | 17259396 | Detail |
0.032 | myocardial infarction | Association between Pro12Ala polymorphism of peroxisome proliferator-activated r... | BeFree | 16881538 | Detail |
0.010 | hyperinsulinism | We investigated individual and combined associations of Pro12Ala and His447His p... | BeFree | 23748472 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma c... | BeFree | 15782399 | Detail |
0.003 | polycystic ovary syndrome | The association between Pro12Ala polymorphism in peroxisome proliferator-activat... | BeFree | 22729915 | Detail |
0.004 | Kidney Diseases | Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated... | BeFree | 22619290 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | We were able to confirm only one association, that of the common Pro12Ala polymo... | BeFree | 10973253 | Detail |
0.001 | Coronary heart disease | Our study in healthy Dutch women in combination with the meta-analyses of previo... | BeFree | 18561518 | Detail |
0.002 | Carcinoma of bladder | Using the TaqMan method, we genotyped single nucleotide polymorphisms in interle... | BeFree | 16110031 | Detail |
0.153 | atherosclerosis | Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro1... | BeFree | 25159899 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The influence of the Pro12Ala mutation of the PPAR-gamma receptor gene on metabo... | BeFree | 12406034 | Detail |
0.316 | Diabetes Mellitus, Non-Insulin-Dependent | In fact, we evaluated the effect of seven polymorphisms in the following genes-P... | BeFree | 23249316 | Detail |
<0.001 | Cardiovascular Diseases | We examined the relationship between two PPAR-gamma gene polymorphisms, namely t... | BeFree | 18417957 | Detail |
<0.001 | renal cell carcinoma | Opposite association of two PPARG variants with cancer: overrepresentation of H4... | BeFree | 11511919 | Detail |
0.017 | Diabetes | The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PP... | BeFree | 19436234 | Detail |
0.004 | Ovarian Diseases | In the present study we have examined the relationship of the Pro(12)Ala polymor... | BeFree | 11836319 | Detail |
0.004 | Diabetes Mellitus, Non-Insulin-Dependent | The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2)... | BeFree | 15562396 | Detail |
0.316 | Diabetes Mellitus, Non-Insulin-Dependent | To analyze the relationship between the peroxisome proliferator-activated recept... | BeFree | 12218380 | Detail |
0.163 | diabetes mellitus | The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... | BeFree | 17052804 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor (PPA... | BeFree | 19808901 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | Association between the P12A and c1431t polymorphisms in the peroxisome prolifer... | BeFree | 11409297 | Detail |
0.163 | diabetes mellitus | The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PP... | BeFree | 19436234 | Detail |
0.007 | gestational diabetes | The other polymorphisms studied were not significantly associated with gestation... | BeFree | 17342473 | Detail |
0.009 | lipodystrophy | PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related li... | BeFree | 19534662 | Detail |
0.143 | diabetes mellitus | Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... | BeFree | 16567542 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) P... | BeFree | 17434720 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... | BeFree | 16804087 | Detail |
0.010 | Coronary Arteriosclerosis | The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamm... | BeFree | 23300871 | Detail |
0.037 | colorectal cancer | We have studied the association between single nucleotide polymorphisms in the i... | BeFree | 12839942 | Detail |
0.004 | Ovarian Diseases | We did not find statistically significant differences with peroxisome proliferat... | BeFree | 16600233 | Detail |
0.039 | colorectal cancer | Influence of the C161T but not Pro12Ala polymorphism in the peroxisome prolifera... | BeFree | 16108832 | Detail |
0.017 | Diabetes | The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... | BeFree | 17052804 | Detail |
0.439 | obesity | The Pro12Ala polymorphism of PPARG was significantly associated with obesity (OR... | BeFree | 25127329 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala polymorphism (rs1801282), a nonsynonymous substitution of peroxisom... | BeFree | 19745552 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes wi... | BeFree | 14730381 | Detail |
0.016 | diabetes mellitus | There was no convincing association between any polymorphism of PPARα and PPARγ ... | BeFree | 21877956 | Detail |
0.002 | obesity | The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARga... | BeFree | 16253648 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | We did not find any significant association between three SNPs in the PGC-1alpha... | BeFree | 17479445 | Detail |
0.001 | Ischemic Cerebrovascular Accident | Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associ... | BeFree | 17359638 | Detail |
0.005 | stomach carcinoma | Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism could be ... | BeFree | 25824760 | Detail |
0.102 | Diabetic Nephropathy | Relationship between PPARγ Pro12Ala gene polymorphism and type 2 diabetic nephro... | BeFree | 24303936 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated... | BeFree | 22619290 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary he... | BeFree | 21833536 | Detail |
<0.001 | Insulin resistance syndrome | Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Dani... | BeFree | 12161548 | Detail |
0.004 | Diabetes Mellitus, Non-Insulin-Dependent | An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) P... | BeFree | 17434720 | Detail |
<0.001 | Impaired cognition | The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... | BeFree | 19766907 | Detail |
<0.001 | Adenoma of large intestine | Larger studies are needed to validate these results, which suggest that the PPAR... | BeFree | 15564289 | Detail |
0.003 | obesity | The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated recepto... | BeFree | 14981210 | Detail |
0.017 | Diabetes | PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diab... | BeFree | 18280041 | Detail |
0.004 | Malignant tumor of colon | There was a significant interaction between the -200A>C IGFBP3 polymorphism a... | BeFree | 16489531 | Detail |
0.439 | obesity | PPARγ Pro12Ala interacts with fat intake for obesity and weight loss in a behavi... | BeFree | 22102511 | Detail |
0.017 | Diabetes | The role of the Pro12Ala polymorphism in peroxisome proliferator-activated recep... | BeFree | 17563457 | Detail |
0.005 | Lipid Metabolism Disorders | The aim of the present study was to investigate the relation between TG-related ... | BeFree | 12042669 | Detail |
0.439 | obesity | We investigated a possible association of PPARg2 Pro12Ala polymorphism with obes... | BeFree | 22653647 | Detail |
0.009 | hyperglycemia | The PPARG Pro12Ala polymorphism is associated with a decreased risk of developin... | BeFree | 16567542 | Detail |
0.011 | colorectal carcinoma | Influence of the C161T but not Pro12Ala polymorphism in the peroxisome prolifera... | BeFree | 16108832 | Detail |
0.003 | Diabetes | There was no convincing association between any polymorphism of PPARα and PPARγ ... | BeFree | 21877956 | Detail |
0.439 | obesity | In conclusion, the higher frequency of the C-->T substitution in exon 6 of th... | BeFree | 14671186 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | In contrast, the well-documented associations of peroxisome proliferator-activat... | BeFree | 15561965 | Detail |
<0.001 | metabolic disturbance | Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro1... | BeFree | 25159899 | Detail |
0.017 | Diabetes | Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasm... | BeFree | 14729856 | Detail |
0.011 | colorectal carcinoma | In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma... | BeFree | 15860437 | Detail |
0.015 | Carcinogenesis | Association between peroxisome proliferator-activated receptor-γ gene polymorphi... | BeFree | 20568969 | Detail |
<0.001 | colorectal cancer | This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphi... | BeFree | 20596649 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... | BeFree | 17213274 | Detail |
0.128 | Dyslipidemias | The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated... | BeFree | 11158005 | Detail |
0.102 | Diabetic Nephropathy | The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... | BeFree | 17493550 | Detail |
0.010 | gestational diabetes | We hypothesized that interaction between PPARG2 Pro12Ala and variants in the pro... | BeFree | 18162503 | Detail |
0.011 | endometriosis | Association of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala polym... | BeFree | 20560917 | Detail |
0.163 | diabetes mellitus | Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with... | BeFree | 21795447 | Detail |
0.032 | Metabolic syndrome X | The Pro12Ala PPARG sequence variant together with a non-E3/E3 APOE genotype is a... | BeFree | 16916989 | Detail |
0.258 | Hypertensive disease | The Pro12Ala and the 4a/b polymorphisms of the peroxisome proliferator-activated... | BeFree | 15662218 | Detail |
0.163 | diabetes mellitus | There appears to be certain genes which predispose Indians to diabetes while oth... | BeFree | 17496355 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala polymorphism of PPARG was significantly associated with obesity (OR... | BeFree | 25127329 | Detail |
0.003 | diabetes mellitus | Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... | BeFree | 17213274 | Detail |
0.163 | diabetes mellitus | Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12... | BeFree | 17941898 | Detail |
0.011 | colorectal carcinoma | We have studied the association between single nucleotide polymorphisms in the i... | BeFree | 12839942 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The association between the peroxisome proliferator-activated receptor-gamma2 (P... | BeFree | 20179158 | Detail |
0.163 | diabetes mellitus | Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... | BeFree | 16567542 | Detail |
0.006 | Inflammatory Bowel Diseases | Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (P... | BeFree | 19104705 | Detail |
0.004 | Ovarian Diseases | Our findings suggest that Pro12Ala PPAR-gamma gene polymorphism may be protectiv... | BeFree | 16316841 | Detail |
0.039 | colorectal cancer | This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphi... | BeFree | 20596649 | Detail |
0.163 | diabetes mellitus | Pro12Ala missense mutation of the peroxisome proliferator activated receptor gam... | BeFree | 9918859 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated recepto... | BeFree | 14981210 | Detail |
0.010 | hyperinsulinism | The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is as... | BeFree | 15853827 | Detail |
<0.001 | colorectal carcinoma | In this study, we evaluated the association between colorectal cancer and specif... | BeFree | 16489531 | Detail |
0.003 | Hypercholesterolemia | For the Pro12Ala polymorphism in PPARγ, although patients with the Pro/Ala genot... | BeFree | 23145084 | Detail |
0.006 | rheumatoid arthritis | The purpose of this study was to examine whether a Proline (Pro)-to-Alanine (Ala... | BeFree | 24697566 | Detail |
0.162 | polycystic ovary syndrome | To investigate the influence of the peroxisome proliferator activated receptor g... | BeFree | 22527903 | Detail |
0.004 | Malignant neoplasm of stomach | Our study suggests that the PPARgamma Pro12Ala polymorphism may be a shared risk... | BeFree | 17763950 | Detail |
0.003 | Diabetes Mellitus, Non-Insulin-Dependent | In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegre... | BeFree | 25157153 | Detail |
0.439 | obesity | Here, we investigated the expression of APM1 in adipose tissue and studied the r... | BeFree | 16231017 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident... | BeFree | 22515931 | Detail |
0.010 | hyperinsulinism | Pro12Ala, a missense mutation in exon 2 of PPARG, reduces transcriptional activi... | BeFree | 20368233 | Detail |
0.014 | Malignant neoplasm of prostate | Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (P... | BeFree | 12609711 | Detail |
0.007 | gestational diabetes | Quantitative assessment of the influence of PPARG P12A polymorphism on gestation... | BeFree | 23054024 | Detail |
0.287 | Diabetes Mellitus, Non-Insulin-Dependent | The present study demonstrates that the AA genotype of the Gly482Ser polymorphis... | BeFree | 15782399 | Detail |
0.007 | Overweight | The goal of this study was to examine whether the Pro12Ala polymorphism of perox... | BeFree | 22102511 | Detail |
0.004 | Malignant neoplasm of stomach | Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism could be ... | BeFree | 25824760 | Detail |
<0.001 | Acne Vulgaris | The Pro12Ala polymorphism of the gene for peroxisome proliferator activated rece... | BeFree | 24984871 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a co... | BeFree | 25063576 | Detail |
0.017 | Diabetes | There appears to be certain genes which predispose Indians to diabetes while oth... | BeFree | 17496355 | Detail |
0.037 | Metabolic syndrome X | PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribu... | BeFree | 22168210 | Detail |
<0.001 | endometrial carcinoma | No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer ... | BeFree | 15608564 | Detail |
0.163 | diabetes mellitus | PPARG P12A (rs1801282) was not significantly associated with diabetes or related... | BeFree | 17903298 | Detail |
0.005 | Carcinoma of bladder | Using the TaqMan method, we genotyped single nucleotide polymorphisms in interle... | BeFree | 16110031 | Detail |
0.007 | Metabolic syndrome X | There was no convincing association between any polymorphism of PPARα and PPARγ ... | BeFree | 21877956 | Detail |
0.004 | Ovarian Diseases | The Pro12Ala polymorphism of the PPARgamma gene is associated with increased ins... | BeFree | 15853827 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | To explore the way that population description is used to replicate and/or exten... | BeFree | 20157827 | Detail |
0.007 | Hyperlipidemia | A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-... | BeFree | 11248748 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Common polymorphisms of the peroxisome proliferator-activated receptor-gamma (Pr... | BeFree | 20045142 | Detail |
0.001 | Helicobacter pylori infection | The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastr... | BeFree | 18372284 | Detail |
0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Four of the nine SNPs revealed a significant association with T2D; PPARG2 (Pro12... | BeFree | 18598350 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The common Pro12Ala polymorphism in PPARgamma is associated with lower diastolic... | BeFree | 12923397 | Detail |
<0.001 | Coronary Arteriosclerosis | Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary he... | BeFree | 21833536 | Detail |
0.020 | coronary artery disease | No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery ... | BeFree | 17322631 | Detail |
0.011 | Acute coronary syndrome | PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospec... | BeFree | 19500413 | Detail |
0.003 | Diabetes | The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... | BeFree | 17493550 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The common Pro12Ala polymorphism in peroxisome proliferator-activated receptor-γ... | BeFree | 23014256 | Detail |
0.439 | obesity | The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator... | BeFree | 15784141 | Detail |
0.007 | gestational diabetes | Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotype... | BeFree | 21795447 | Detail |
0.009 | sarcoidosis | Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and perox... | BeFree | 19070258 | Detail |
<0.001 | colorectal carcinoma | In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma... | BeFree | 15860437 | Detail |
0.145 | Metabolic syndrome X | Associations between C1431T and Pro12Ala variants of PPARγ gene and their haplot... | BeFree | 24464185 | Detail |
0.008 | diabetic retinopathy | Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma c... | BeFree | 15782399 | Detail |
0.439 | obesity | Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala vari... | BeFree | 11158005 | Detail |
0.062 | polycystic ovary syndrome | A meta-analysis on the association between PPAR-γ Pro12Ala polymorphism and poly... | BeFree | 22527903 | Detail |
0.003 | Non-alcoholic Fatty Liver Disease | Association between the Pro12Ala polymorphism of PPAR-γ gene and the non-alcohol... | BeFree | 23891820 | Detail |
0.287 | Diabetes Mellitus, Non-Insulin-Dependent | Evidence for interaction between PPARG Pro12Ala and PPARGC1A Gly482Ser polymorph... | BeFree | 19536736 | Detail |
0.134 | colon carcinoma | There was a significant interaction between the -200A>C IGFBP3 polymorphism a... | BeFree | 16489531 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Polymorphism of peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala in... | BeFree | 21968139 | Detail |
<0.001 | Carotid Atherosclerosis | We investigated the relationship between 2 common PPARG polymorphisms, namely P1... | BeFree | 15284449 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala polymorp... | BeFree | 19846795 | Detail |
0.439 | obesity | Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activ... | BeFree | 19733160 | Detail |
0.145 | Metabolic syndrome X | The Pro12Ala PPARgamma polymorphism does not seem to be associated with BMI or m... | BeFree | 19609844 | Detail |
0.439 | obesity | The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARga... | BeFree | 16253648 | Detail |
0.003 | Malignant neoplasm of pancreas | Association between the peroxisome proliferator-activated receptor gamma Pro12Al... | BeFree | 19436234 | Detail |
<0.001 | colorectal cancer | In this study, we evaluated the association between colorectal cancer and specif... | BeFree | 16489531 | Detail |
0.163 | diabetes mellitus | Our findings suggest that Pro12Ala PPAR-gamma gene polymorphism may be protectiv... | BeFree | 16316841 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamm... | BeFree | 18467141 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | These results suggest that in the Taiwanese, the Pro12Ala PPARgamma2 gene varian... | BeFree | 11079814 | Detail |
0.010 | Coronary Arteriosclerosis | Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident... | BeFree | 22515931 | Detail |
0.062 | polycystic ovary syndrome | The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is as... | BeFree | 15853827 | Detail |
0.026 | colorectal cancer | We have studied the association between single nucleotide polymorphisms in the i... | BeFree | 12839942 | Detail |
0.614 | Diabetes Mellitus, Non-Insulin-Dependent | Four of the nine SNPs revealed a significant association with T2D; PPARG2 (Pro12... | BeFree | 18598350 | Detail |
0.062 | polycystic ovary syndrome | Lack of an association between peroxisome proliferator-activated receptor-gamma ... | BeFree | 15472214 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Evidence for interaction between PPARG Pro12Ala and PPARGC1A Gly482Ser polymorph... | BeFree | 19536736 | Detail |
<0.001 | colorectal carcinoma | This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphi... | BeFree | 20596649 | Detail |
<0.001 | acute myocardial infarction | The alanine allele of P12A polymorphism in PPARG gene in a few studies has been ... | BeFree | 18561518 | Detail |
<0.001 | Pediatric Obesity | Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphi... | BeFree | 19634985 | Detail |
0.258 | Hypertensive disease | The data suggest a contribution of the Pro12Ala polymorphism of PPARgamma to gen... | BeFree | 15563983 | Detail |
<0.001 | hyperglycemia | The PPARG Pro12Ala polymorphism is associated with a decreased risk of developin... | BeFree | 16567542 | Detail |
0.439 | obesity | Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with ... | BeFree | 17624182 | Detail |
0.012 | Impaired glucose tolerance | Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... | BeFree | 16804087 | Detail |
0.013 | Malignant tumor of colon | There was a significant interaction between the -200A>C IGFBP3 polymorphism a... | BeFree | 16489531 | Detail |
0.001 | Coronary heart disease | The meta-analysis of the association of PPARG P12A, C161T polymorphism and coron... | BeFree | 22987045 | Detail |
0.145 | Metabolic syndrome X | Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Dani... | BeFree | 12161548 | Detail |
0.094 | arteriosclerosis | The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated recept... | BeFree | 25096510 | Detail |
0.007 | colorectal carcinoma | We have studied the association between single nucleotide polymorphisms in the i... | BeFree | 12839942 | Detail |
0.163 | diabetes mellitus | Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabete... | BeFree | 23006958 | Detail |
0.002 | Rectal Carcinoma | For rectal cancer there was a significant interaction between the Bsm1/polyA pol... | BeFree | 16489531 | Detail |
<0.001 | Impaired glucose tolerance | Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... | BeFree | 16804087 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Is it time to conduct a hypothesis-driven large-scale exercise training interven... | BeFree | 22672138 | Detail |
0.321 | Diabetes Mellitus, Non-Insulin-Dependent | Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is... | BeFree | 12218380 | Detail |
0.008 | diabetic retinopathy | The association of non-synonymous substitution polymorphism rs1801282 (c.34C>... | BeFree | 23559865 | Detail |
<0.001 | Diabetes | Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on di... | BeFree | 16567542 | Detail |
0.439 | obesity | A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-... | BeFree | 11248748 | Detail |
0.439 | obesity | The peroxisome proliferator-activated receptor gamma 2 Pro12Ala mutation is asso... | BeFree | 10873398 | Detail |
0.003 | diabetes mellitus | PPARG P12A (rs1801282) was not significantly associated with diabetes or related... | BeFree | 17903298 | Detail |
0.145 | Metabolic syndrome X | Pro12Ala sequence variant of the PPARG gene is associated with postprandial hype... | BeFree | 16916989 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associ... | BeFree | 17493550 | Detail |
0.001 | Helicobacter pylori infection | Nevertheless, prospectively designed cohort studies are needed to further invest... | BeFree | 25824760 | Detail |
0.006 | rheumatoid arthritis | These observations suggest that Pro12Ala (rs1801282), a coding variant in the PP... | BeFree | 23633103 | Detail |
<0.001 | Impaired glucose tolerance | The proline allele at PPARG P12A increases risk for diabetes in persons with imp... | BeFree | 17213274 | Detail |
0.017 | Diabetes | Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... | BeFree | 17213274 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator... | BeFree | 15784141 | Detail |
<0.001 | Diabetes Mellitus, Non-Insulin-Dependent | Hence, our aim was to develop a low-cost method for the validation of PPARG (Pro... | BeFree | 25063576 | Detail |
0.139 | obesity | In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotyp... | BeFree | 24200052 | Detail |
0.374 | Diabetes Mellitus, Non-Insulin-Dependent | Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mell... | BeFree | 16920849 | Detail |
0.026 | Coronary heart disease | No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery ... | BeFree | 17322631 | Detail |
0.003 | diabetes mellitus | The genetic influence of PPARG P12A genotype is modest and is overshadowed by du... | BeFree | 17493550 | Detail |
0.145 | Metabolic syndrome X | The frequencies of 2 common polymorphisms of the PPARgamma gene, Pro12Ala single... | BeFree | 18362424 | Detail |
<0.001 | gastric adenocarcinoma | The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastr... | BeFree | 18372284 | Detail |
0.039 | colorectal cancer | Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the P... | BeFree | 16965392 | Detail |
0.017 | Diabetes | The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gen... | BeFree | 17898990 | Detail |
0.026 | Coronary heart disease | The aim was to investigate if the polymorphism PPARgamma2 Pro12Ala, which encode... | BeFree | 19500413 | Detail |
<0.001 | gestational diabetes | The other polymorphisms studied were not significantly associated with gestation... | BeFree | 17342473 | Detail |
0.439 | obesity | The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamm... | BeFree | 25182148 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Examining the relationships between the Pro12Ala variant in PPARG and Type 2 dia... | BeFree | 16401314 | Detail |
0.020 | Ovarian Diseases | Compared with first-degree relatives of PCOS subjects with the Pro12Pro polymorp... | BeFree | 16316841 | Detail |
0.374 | Diabetes Mellitus, Non-Insulin-Dependent | Together, these results showed that PPARG Pro12Ala and PPARGC1A Gly482Ser varian... | BeFree | 19536736 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (... | BeFree | 17439324 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The data suggest a contribution of the Pro12Ala polymorphism of PPARgamma to gen... | BeFree | 15563983 | Detail |
0.009 | lipodystrophy | In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegre... | BeFree | 25157153 | Detail |
0.001 | Ischemic stroke | Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associ... | BeFree | 17359638 | Detail |
<0.001 | acne | The Pro12Ala polymorphism of the gene for peroxisome proliferator activated rece... | BeFree | 24984871 | Detail |
0.002 | obesity | The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated... | BeFree | 11158005 | Detail |
0.003 | Non-alcoholic Fatty Liver Disease | Meta-analysis of associations between the peroxisome proliferator-activated rece... | BeFree | 24697566 | Detail |
0.032 | myocardial infarction | We conclude that PPARg2 Pro12Ala polymorphisms are associated with increased ris... | BeFree | 22653647 | Detail |
0.439 | obesity | The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (P... | BeFree | 17052804 | Detail |
0.017 | Diabetes | The authors highlight these challenges and biases using an illustrative example:... | BeFree | 20406760 | Detail |
0.010 | Coronary Arteriosclerosis | No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery ... | BeFree | 17322631 | Detail |
0.010 | prostate carcinoma | Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (P... | BeFree | 12609711 | Detail |
0.094 | Diabetes Mellitus, Non-Insulin-Dependent | In fact, we evaluated the effect of seven polymorphisms in the following genes-P... | BeFree | 23249316 | Detail |
0.003 | Osteoarthritis, Knee | Prevalence of the Pro12Ala missense mutation in the PPARG2 gene in Kuwaiti patie... | BeFree | 21245597 | Detail |
<0.001 | endometrial carcinoma | Opposite association of two PPARG variants with cancer: overrepresentation of H4... | BeFree | 11511919 | Detail |
0.004 | Ovarian Diseases | We suggest that Pro12Ala polymorphism of the PPAR-gamma gene may be a modifier o... | BeFree | 16785159 | Detail |
0.002 | colon carcinoma | There was a significant interaction between the -200A>C IGFBP3 polymorphism a... | BeFree | 16489531 | Detail |
0.439 | obesity | The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gen... | BeFree | 17898990 | Detail |
0.322 | Diabetes Mellitus, Non-Insulin-Dependent | PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in As... | BeFree | 19846176 | Detail |
0.081 | diabetic retinopathy | The present study demonstrates that the AA genotype of the Gly482Ser polymorphis... | BeFree | 15782399 | Detail |
0.062 | polycystic ovary syndrome | Association between the Pro12Ala polymorphism of PPAR-γ gene and the polycystic ... | BeFree | 22564702 | Detail |
<0.001 | Metabolic syndrome X | Our objective was to search for differences in genotypes of peroxisome prolifera... | BeFree | 16216916 | Detail |
0.015 | breast carcinoma | A marginally significant increased risk of breast cancer was observed among wome... | BeFree | 17348446 | Detail |
0.026 | Coronary heart disease | The meta-analysis of the association of PPARG P12A, C161T polymorphism and coron... | BeFree | 22987045 | Detail |
0.140 | Metabolic syndrome X | In the group of participants with PPARγ Pro12Ala or Ala12Ala genotypes, those wi... | BeFree | 24200052 | Detail |
0.102 | Diabetic Nephropathy | Pro12Ala polymorphism in the PPARG gene contributes to the development of diabet... | BeFree | 19837787 | Detail |
0.004 | pancreatic carcinoma | Association between the peroxisome proliferator-activated receptor gamma Pro12Al... | BeFree | 19436234 | Detail |
0.004 | Diabetes Mellitus, Non-Insulin-Dependent | Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser subst... | BeFree | 16804087 | Detail |
0.163 | diabetes mellitus | PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diab... | BeFree | 18280041 | Detail |
0.004 | Ovarian Diseases | This study has shown that both Pro12Ala and His447His polymorphisms of PPAR-gamm... | BeFree | 19549442 | Detail |
0.439 | obesity | The single nucleotide polymorphisms (SNPs) of the above genes, such as GNB3-C825... | BeFree | 24827746 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: ... | BeFree | 18598350 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be asso... | BeFree | 18077048 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression... | BeFree | 17213274 | Detail |
0.026 | Coronary heart disease | We examined the relationship between PPARG2 P12A and CHD risk in women (Nurses' ... | BeFree | 15920035 | Detail |
0.039 | colorectal cancer | In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma... | BeFree | 15860437 | Detail |
<0.001 | Diabetic Nephropathy | We conclude that P12A and C161T polymorphisms of the PPAR-gamma gene are importa... | BeFree | 18417957 | Detail |
0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The protective role of the Ala allele in the Pro12Ala polymorphism of PPARγ on t... | BeFree | 21795447 | Detail |
0.021 | Cardiovascular Diseases | Two PPARg common polymorphisms, Pro12Ala and 161C>T, have been found to be as... | BeFree | 19117570 | Detail |
<0.001 | colorectal cancer | In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma... | BeFree | 15860437 | Detail |
0.153 | atherosclerosis | The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated recept... | BeFree | 25096510 | Detail |
0.006 | Inflammatory Bowel Diseases | Association between the Pro12Ala polymorphism of peroxisome proliferator-activat... | BeFree | 22276212 | Detail |
0.439 | obesity | The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated recepto... | BeFree | 14981210 | Detail |
0.439 | obesity | In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotyp... | BeFree | 24200052 | Detail |
0.017 | Diabetes | Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with... | BeFree | 21795447 | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NM_138711.6(PPARG):c.28C>G (p.Pro10Ala) AND Diabetes mellitus, noninsulin-dependent, modifier of | ClinVar | Detail |
NM_138711.6(PPARG):c.28C>G (p.Pro10Ala) AND Obesity, modifier of | ClinVar | Detail |
NM_138711.6(PPARG):c.28C>G (p.Pro10Ala) AND Body mass index, modifier of | ClinVar | Detail |
NM_138711.6(PPARG):c.28C>G (p.Pro10Ala) AND Intimal medial thickness of internal carotid artery, mod... | ClinVar | Detail |
Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP A19G), the leptin r... | DisGeNET | Detail |
Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP A19G), the leptin r... | DisGeNET | Detail |
Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP A19G), the leptin r... | DisGeNET | Detail |
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... | DisGeNET | Detail |
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... | DisGeNET | Detail |
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... | DisGeNET | Detail |
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... | DisGeNET | Detail |
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... | DisGeNET | Detail |
In obese subjects, associations with T2D were detected with PPARG Pro12Ala (OR = 0.73, P = 0.004), A... | DisGeNET | Detail |
Seven variants displaying conflicting results in previous reports and supposedly implicated in the s... | DisGeNET | Detail |
Seven variants displaying conflicting results in previous reports and supposedly implicated in the s... | DisGeNET | Detail |
Seven variants displaying conflicting results in previous reports and supposedly implicated in the s... | DisGeNET | Detail |
Seven variants displaying conflicting results in previous reports and supposedly implicated in the s... | DisGeNET | Detail |
We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), TNFalpha (-308G>A... | DisGeNET | Detail |
We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), TNFalpha (-308G>A... | DisGeNET | Detail |
We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), TNFalpha (-308G>A... | DisGeNET | Detail |
We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), TNFalpha (-308G>A... | DisGeNET | Detail |
We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), TNFalpha (-308G>A... | DisGeNET | Detail |
We studied the association of SNPs in the IL-6 (-174G>C), IL-8 (-251T>A), TNFalpha (-308G>A... | DisGeNET | Detail |
The frequency distribution of rare alleles for PPARα (L162V) and PPARγ (P12A and H449H) was compared... | DisGeNET | Detail |
The objective of this study was to analyze the polymorphisms Leu162Val of PPARα and Pro12Ala of PPAR... | DisGeNET | Detail |
The frequency distribution of rare alleles for PPARα (L162V) and PPARγ (P12A and H449H) was compared... | DisGeNET | Detail |
The objective of this study was to analyze the polymorphisms Leu162Val of PPARα and Pro12Ala of PPAR... | DisGeNET | Detail |
We investigated the association of two common single nucleotide polymorphisms in the PPARA (Leu162Va... | DisGeNET | Detail |
Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala, have recently been... | DisGeNET | Detail |
The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes. | DisGeNET | Detail |
Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala, have recently been... | DisGeNET | Detail |
The association of the Pro12Ala and Pro115Gln PPARgamma2 gene variants with type 2 diabetes mellitus... | DisGeNET | Detail |
The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes. | DisGeNET | Detail |
Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala, have recently been... | DisGeNET | Detail |
The association of the Pro12Ala and Pro115Gln PPARgamma2 gene variants with type 2 diabetes mellitus... | DisGeNET | Detail |
Two naturally occurring mutations in the PPAR gamma gene, Pro115Gln and Pro12Ala, have recently been... | DisGeNET | Detail |
We have genotyped three single nucleotide polymorphisms associated with type 2 diabetes in a large t... | DisGeNET | Detail |
By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and 44)... | DisGeNET | Detail |
The peroxisome proliferator-activated receptor gamma (PPARG), Pro12Ala and the insulin receptor subs... | DisGeNET | Detail |
By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and 44)... | DisGeNET | Detail |
By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and 44)... | DisGeNET | Detail |
We have genotyped three single nucleotide polymorphisms associated with type 2 diabetes in a large t... | DisGeNET | Detail |
By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and 44)... | DisGeNET | Detail |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARG; NCBI dbSNP rs1... | DisGeNET | Detail |
Although cross-sectional studies have associated the Pro12Ala polymorphism of PPARG with type 2 diab... | DisGeNET | Detail |
The proline allele at PPARG P12A increases risk for diabetes in persons with impaired glucose tolera... | DisGeNET | Detail |
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obes... | DisGeNET | Detail |
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... | DisGeNET | Detail |
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... | DisGeNET | Detail |
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... | DisGeNET | Detail |
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G... | DisGeNET | Detail |
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... | DisGeNET | Detail |
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNF... | DisGeNET | Detail |
The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) Pro12Ala (P12A) pol... | DisGeNET | Detail |
Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-... | DisGeNET | Detail |
We were unable to replicate in a Caucasian cohort the recent association between PPARγ C161T and UC ... | DisGeNET | Detail |
The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascular risk is controve... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associated with nephropath... | DisGeNET | Detail |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... | DisGeNET | Detail |
Pro12Ala mutation decreases PPARG activity and resistance to NIDDM. | DisGeNET | Detail |
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... | DisGeNET | Detail |
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... | DisGeNET | Detail |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARgamma) has been a... | DisGeNET | Detail |
The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene has been i... | DisGeNET | Detail |
The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated receptor gamma 2 (PPAR gamm... | DisGeNET | Detail |
Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with insulin resistance a... | DisGeNET | Detail |
The results of the present study demonstrated that possessing the A allele of RAGE -374T/A polymorph... | DisGeNET | Detail |
PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatty liver in middle-ag... | DisGeNET | Detail |
The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascular risk is controve... | DisGeNET | Detail |
We aimed to estimate the association between the common Pro12Ala polymorphism of PPARG2 and risk of ... | DisGeNET | Detail |
Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients... | DisGeNET | Detail |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... | DisGeNET | Detail |
Pro12Ala polymorphism in human peroxisome proliferator activated receptor gamma is associated with h... | DisGeNET | Detail |
Association of peroxisome proliferator-activated receptor γ Pro12Ala gene polymorphism with type 2 d... | DisGeNET | Detail |
In conclusion, the higher frequency of the C-->T substitution in exon 6 of the PPAR-gamma gene in... | DisGeNET | Detail |
The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated receptor gamma(2) (... | DisGeNET | Detail |
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma 2 gene is suggeste... | DisGeNET | Detail |
PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. | DisGeNET | Detail |
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over... | DisGeNET | Detail |
We hypothesized that interaction between PPARG2 Pro12Ala and variants in the promoter region of HNF4... | DisGeNET | Detail |
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... | DisGeNET | Detail |
A marginally significant increased risk of breast cancer was observed among women homozygous for the... | DisGeNET | Detail |
In contrast, the well-documented associations of peroxisome proliferator-activated receptor gamma P1... | DisGeNET | Detail |
We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobacter pylori infection... | DisGeNET | Detail |
Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymor... | DisGeNET | Detail |
Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis. | DisGeNET | Detail |
Our study suggests that the PPARgamma Pro12Ala polymorphism may be a shared risk marker of both IFG ... | DisGeNET | Detail |
The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) Pro12Ala (P12A) pol... | DisGeNET | Detail |
The authors highlight these challenges and biases using an illustrative example: meta-analysis of in... | DisGeNET | Detail |
Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARgamma gene and co... | DisGeNET | Detail |
These results suggest that the PPAR-gamma P12A polymorphism can modulate the association between die... | DisGeNET | Detail |
Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala poly... | DisGeNET | Detail |
The Pro12Ala variant in the PPAR-gamma2 (PPARG) gene was genotyped in 571 non-diabetic relatives of ... | DisGeNET | Detail |
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... | DisGeNET | Detail |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... | DisGeNET | Detail |
Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymor... | DisGeNET | Detail |
In this study, we investigated the association of PPAR-γ gene Pro12Ala (rs1801282) and C1431T (rs385... | DisGeNET | Detail |
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNF... | DisGeNET | Detail |
Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabete... | DisGeNET | Detail |
Previous studies have sought to associate the Pro12Ala variant of the peroxisome proliferator-activa... | DisGeNET | Detail |
PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. | DisGeNET | Detail |
Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients... | DisGeNET | Detail |
This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protec... | DisGeNET | Detail |
The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. | DisGeNET | Detail |
PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pr... | DisGeNET | Detail |
PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes. | DisGeNET | Detail |
We investigated the synergism between variants at the PPARγ locus (C161T and Pro12Ala polymorphisms)... | DisGeNET | Detail |
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... | DisGeNET | Detail |
Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial c... | DisGeNET | Detail |
We genotyped known single nucleotide polymorphisms (SNPs) in the adiponectin-encoding adipocyte C1q ... | DisGeNET | Detail |
The Pro12Ala polymorphism in the gene encoding PPARγ (PPARγ2 gene) influences the risk for type 2 di... | DisGeNET | Detail |
Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-di... | DisGeNET | Detail |
The PPARgamma Pro12Ala polymorphism has been associated in several studies with a decreased risk of ... | DisGeNET | Detail |
The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastric adenocarcinoma an... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism and its reported rela... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and peroxisome proliferator-a... | DisGeNET | Detail |
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with inc... | DisGeNET | Detail |
Our study in healthy Dutch women in combination with the meta-analyses of previous reports does not ... | DisGeNET | Detail |
The association of the C1431T silent mutation and the Pro12Ala missense transversion within the PPAR... | DisGeNET | Detail |
These results suggest that the PPARgamma is a thrifty gene and that the Pro12Ala PPARgamma2 polymorp... | DisGeNET | Detail |
To explore the relationship between the genetic polymorphisms of PPARgamma (Pro12Ala, C1431T, and C-... | DisGeNET | Detail |
Although the study was carried out on a sufficiently large sample, the conclusions do not support a ... | DisGeNET | Detail |
PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy. | DisGeNET | Detail |
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... | DisGeNET | Detail |
PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribution, but not metabo... | DisGeNET | Detail |
The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. | DisGeNET | Detail |
Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with polycy... | DisGeNET | Detail |
The P12A variant in the PPARG gene and the E23K polymorphism in KCNJ11 are both known to influence i... | DisGeNET | Detail |
Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a cost effective way for... | DisGeNET | Detail |
Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be associated with decrease... | DisGeNET | Detail |
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is... | DisGeNET | Detail |
We also investigated the possible association between PPARgamma Pro12Ala polymorphism and dementia o... | DisGeNET | Detail |
Association between peroxisome proliferator-activated receptor-γ gene polymorphism (Pro12Ala) and He... | DisGeNET | Detail |
Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral ... | DisGeNET | Detail |
Association between the P12A and c1431t polymorphisms in the peroxisome proliferator activated recep... | DisGeNET | Detail |
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... | DisGeNET | Detail |
In conclusion, our results confirm that adiponectin concentrations are similar in PCOS and controls ... | DisGeNET | Detail |
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in women with pol... | DisGeNET | Detail |
In contrast, the well-documented associations of peroxisome proliferator-activated receptor gamma P1... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro12Ala) polymorphism h... | DisGeNET | Detail |
Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala polymorphism with endom... | DisGeNET | Detail |
Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala on ethnic suscep... | DisGeNET | Detail |
The distribution of the Pro(12)Ala PPAR gamma gene polymorphism is equally present in patients with ... | DisGeNET | Detail |
We also investigated the possible association between PPARgamma Pro12Ala polymorphism and dementia o... | DisGeNET | Detail |
Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart dise... | DisGeNET | Detail |
The Pro12Ala polymorphism in the PPAR-gamma gene has been associated with reduced incidence of type ... | DisGeNET | Detail |
Our results suggest that the Pro12Ala polymorphism of the PPARgamma-2 gene promotes peripheral depos... | DisGeNET | Detail |
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is... | DisGeNET | Detail |
Pro12Ala sequence variant of the PPARG gene is associated with postprandial hypertriglyceridemia in ... | DisGeNET | Detail |
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is... | DisGeNET | Detail |
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... | DisGeNET | Detail |
For rectal cancer there was a significant interaction between the Bsm1/polyA polymorphisms (p = 0.00... | DisGeNET | Detail |
Conflicting evidence exists as to whether the Pro12Ala single nucleotide polymorphism of the type 2 ... | DisGeNET | Detail |
We investigated the association of Pro12Ala PPARgamma polymorphism and Helicobacter pylori infection... | DisGeNET | Detail |
Cardiovascular risk factors related to the PPARγ Pro12Ala polymorphism in patients with type 2 diabe... | DisGeNET | Detail |
The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene has been i... | DisGeNET | Detail |
Association of Pro12Ala polymorphism in peroxisome proliferator activated receptor gamma with prolif... | DisGeNET | Detail |
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in first-degree r... | DisGeNET | Detail |
Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 ... | DisGeNET | Detail |
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... | DisGeNET | Detail |
The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabete... | DisGeNET | Detail |
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G... | DisGeNET | Detail |
A population-attributable risk of approximately 50% for the Pro12Pro genotype indicates that testing... | DisGeNET | Detail |
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma 2 gene is suggeste... | DisGeNET | Detail |
We investigated the effects of the common polymorphisms in the peroxisome proliferator-activated rec... | DisGeNET | Detail |
In conclusion, the PPARG Pro12Ala polymorphism might represent a genetic susceptibility factor for p... | DisGeNET | Detail |
Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and ... | DisGeNET | Detail |
We investigated individual and combined associations of Pro12Ala and His447His polymorphisms of PPAR... | DisGeNET | Detail |
Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 gene mi... | DisGeNET | Detail |
The association between Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma (P... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in... | DisGeNET | Detail |
We were able to confirm only one association, that of the common Pro12Ala polymorphism in peroxisome... | DisGeNET | Detail |
Our study in healthy Dutch women in combination with the meta-analyses of previous reports does not ... | DisGeNET | Detail |
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro12Ala) polymorphism h... | DisGeNET | Detail |
The influence of the Pro12Ala mutation of the PPAR-gamma receptor gene on metabolic and clinical cha... | DisGeNET | Detail |
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNF... | DisGeNET | Detail |
We examined the relationship between two PPAR-gamma gene polymorphisms, namely the P12A and C161T, a... | DisGeNET | Detail |
Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial c... | DisGeNET | Detail |
The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PPARG) gene has been a... | DisGeNET | Detail |
In the present study we have examined the relationship of the Pro(12)Ala polymorphism in the PPARgam... | DisGeNET | Detail |
The effects of peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) Pro12Ala (P12A) pol... | DisGeNET | Detail |
To analyze the relationship between the peroxisome proliferator-activated receptor-gamma (PPARgamma2... | DisGeNET | Detail |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) has been ... | DisGeNET | Detail |
The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor (PPAR-gamma) gene is inv... | DisGeNET | Detail |
Association between the P12A and c1431t polymorphisms in the peroxisome proliferator activated recep... | DisGeNET | Detail |
The Pro12Ala variant in the peroxisome proliferator-activated receptor gamma (PPARG) gene has been a... | DisGeNET | Detail |
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... | DisGeNET | Detail |
PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy. | DisGeNET | Detail |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... | DisGeNET | Detail |
An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) Pro12Ala polymorphism... | DisGeNET | Detail |
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... | DisGeNET | Detail |
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is... | DisGeNET | Detail |
We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-... | DisGeNET | Detail |
We did not find statistically significant differences with peroxisome proliferator-activated recepto... | DisGeNET | Detail |
Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator-activated recept... | DisGeNET | Detail |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) has been ... | DisGeNET | Detail |
The Pro12Ala polymorphism of PPARG was significantly associated with obesity (OR=1.74, 95% CI=1.19-2... | DisGeNET | Detail |
The Pro12Ala polymorphism (rs1801282), a nonsynonymous substitution of peroxisome proliferator-activ... | DisGeNET | Detail |
Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to... | DisGeNET | Detail |
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... | DisGeNET | Detail |
The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene has been i... | DisGeNET | Detail |
We did not find any significant association between three SNPs in the PGC-1alpha gene and T2DM in Hi... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associated with the suscep... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism could be a risk factor for ga... | DisGeNET | Detail |
Relationship between PPARγ Pro12Ala gene polymorphism and type 2 diabetic nephropathy risk in Asian ... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in... | DisGeNET | Detail |
Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients... | DisGeNET | Detail |
Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: ho... | DisGeNET | Detail |
An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) Pro12Ala polymorphism... | DisGeNET | Detail |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARgamma) has been a... | DisGeNET | Detail |
Larger studies are needed to validate these results, which suggest that the PPARgamma Pro12Ala polym... | DisGeNET | Detail |
The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated receptor gamma 2 (PPAR gamm... | DisGeNET | Detail |
PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes. | DisGeNET | Detail |
There was a significant interaction between the -200A>C IGFBP3 polymorphism and the Pro12Ala PPAR... | DisGeNET | Detail |
PPARγ Pro12Ala interacts with fat intake for obesity and weight loss in a behavioural treatment base... | DisGeNET | Detail |
The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabete... | DisGeNET | Detail |
The aim of the present study was to investigate the relation between TG-related parameters considere... | DisGeNET | Detail |
We investigated a possible association of PPARg2 Pro12Ala polymorphism with obesity and myocardial i... | DisGeNET | Detail |
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over... | DisGeNET | Detail |
Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator-activated recept... | DisGeNET | Detail |
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... | DisGeNET | Detail |
In conclusion, the higher frequency of the C-->T substitution in exon 6 of the PPAR-gamma gene in... | DisGeNET | Detail |
In contrast, the well-documented associations of peroxisome proliferator-activated receptor gamma P1... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) rs1801282 (Pro12Ala) polymorphism h... | DisGeNET | Detail |
Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabete... | DisGeNET | Detail |
In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma polymorphism and bo... | DisGeNET | Detail |
Association between peroxisome proliferator-activated receptor-γ gene polymorphism (Pro12Ala) and He... | DisGeNET | Detail |
This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protec... | DisGeNET | Detail |
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... | DisGeNET | Detail |
The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated receptor gamma(2) (... | DisGeNET | Detail |
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... | DisGeNET | Detail |
We hypothesized that interaction between PPARG2 Pro12Ala and variants in the promoter region of HNF4... | DisGeNET | Detail |
Association of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala polymorphism with advance... | DisGeNET | Detail |
Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has be... | DisGeNET | Detail |
The Pro12Ala PPARG sequence variant together with a non-E3/E3 APOE genotype is associated with a hig... | DisGeNET | Detail |
The Pro12Ala and the 4a/b polymorphisms of the peroxisome proliferator-activated receptor gamma (PPA... | DisGeNET | Detail |
There appears to be certain genes which predispose Indians to diabetes while other genes (for exampl... | DisGeNET | Detail |
The Pro12Ala polymorphism of PPARG was significantly associated with obesity (OR=1.74, 95% CI=1.19-2... | DisGeNET | Detail |
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... | DisGeNET | Detail |
Genetic polymorphism of peroxisome proliferator-activated receptor-gamma 2 Pro12Ala on ethnic suscep... | DisGeNET | Detail |
We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-... | DisGeNET | Detail |
The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene... | DisGeNET | Detail |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... | DisGeNET | Detail |
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in in... | DisGeNET | Detail |
Our findings suggest that Pro12Ala PPAR-gamma gene polymorphism may be protective against IR and mig... | DisGeNET | Detail |
This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protec... | DisGeNET | Detail |
Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mell... | DisGeNET | Detail |
The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated receptor gamma 2 (PPAR gamm... | DisGeNET | Detail |
The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is associated with a lowe... | DisGeNET | Detail |
In this study, we evaluated the association between colorectal cancer and specific tumor mutations a... | DisGeNET | Detail |
For the Pro12Ala polymorphism in PPARγ, although patients with the Pro/Ala genotype (8.8%) had a hig... | DisGeNET | Detail |
The purpose of this study was to examine whether a Proline (Pro)-to-Alanine (Ala) exchange at codon ... | DisGeNET | Detail |
To investigate the influence of the peroxisome proliferator activated receptor gamma (PPAR-γ) Pro12A... | DisGeNET | Detail |
Our study suggests that the PPARgamma Pro12Ala polymorphism may be a shared risk marker of both IFG ... | DisGeNET | Detail |
In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegregate with lipodystro... | DisGeNET | Detail |
Here, we investigated the expression of APM1 in adipose tissue and studied the relationship between ... | DisGeNET | Detail |
Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart dise... | DisGeNET | Detail |
Pro12Ala, a missense mutation in exon 2 of PPARG, reduces transcriptional activity of PPARgamma2 and... | DisGeNET | Detail |
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) gene and ... | DisGeNET | Detail |
Quantitative assessment of the influence of PPARG P12A polymorphism on gestational diabetes mellitus... | DisGeNET | Detail |
The present study demonstrates that the AA genotype of the Gly482Ser polymorphism in the PPARGC1 gen... | DisGeNET | Detail |
The goal of this study was to examine whether the Pro12Ala polymorphism of peroxisome proliferator-a... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism could be a risk factor for ga... | DisGeNET | Detail |
The Pro12Ala polymorphism of the gene for peroxisome proliferator activated receptor-gamma is associ... | DisGeNET | Detail |
Development of ARMS-PCR assay for genotyping of Pro12Ala SNP of PPARG gene: a cost effective way for... | DisGeNET | Detail |
There appears to be certain genes which predispose Indians to diabetes while other genes (for exampl... | DisGeNET | Detail |
PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribution, but not metabo... | DisGeNET | Detail |
No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer susceptibility. | DisGeNET | Detail |
PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. | DisGeNET | Detail |
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G... | DisGeNET | Detail |
There was no convincing association between any polymorphism of PPARα and PPARγ and each individual ... | DisGeNET | Detail |
The Pro12Ala polymorphism of the PPARgamma gene is associated with increased insulin sensitivity and... | DisGeNET | Detail |
To explore the way that population description is used to replicate and/or extend previously reporte... | DisGeNET | Detail |
A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associate... | DisGeNET | Detail |
Common polymorphisms of the peroxisome proliferator-activated receptor-gamma (Pro12Ala) and peroxiso... | DisGeNET | Detail |
The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastric adenocarcinoma an... | DisGeNET | Detail |
Four of the nine SNPs revealed a significant association with T2D; PPARG2 (Pro12Ala) [odds ratio (OR... | DisGeNET | Detail |
The common Pro12Ala polymorphism in PPARgamma is associated with lower diastolic blood pressure in m... | DisGeNET | Detail |
Effects of the PPARG P12A and C161T gene variants on serum lipids in coronary heart disease patients... | DisGeNET | Detail |
No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery disease in Korean su... | DisGeNET | Detail |
PPARgamma Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes. | DisGeNET | Detail |
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... | DisGeNET | Detail |
The common Pro12Ala polymorphism in peroxisome proliferator-activated receptor-γ (PPAR-γ) gene was c... | DisGeNET | Detail |
The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator-Activated Receptor ... | DisGeNET | Detail |
Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotypes with susceptibilit... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and peroxisome proliferator-a... | DisGeNET | Detail |
In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma polymorphism and bo... | DisGeNET | Detail |
Associations between C1431T and Pro12Ala variants of PPARγ gene and their haplotypes with susceptibi... | DisGeNET | Detail |
Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 gene mi... | DisGeNET | Detail |
Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala variant on obesity, gluc... | DisGeNET | Detail |
A meta-analysis on the association between PPAR-γ Pro12Ala polymorphism and polycystic ovary syndrom... | DisGeNET | Detail |
Association between the Pro12Ala polymorphism of PPAR-γ gene and the non-alcoholic fatty liver disea... | DisGeNET | Detail |
Evidence for interaction between PPARG Pro12Ala and PPARGC1A Gly482Ser polymorphisms in determining ... | DisGeNET | Detail |
There was a significant interaction between the -200A>C IGFBP3 polymorphism and the Pro12Ala PPAR... | DisGeNET | Detail |
Polymorphism of peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala in the Iranian populat... | DisGeNET | Detail |
We investigated the relationship between 2 common PPARG polymorphisms, namely P12A and c.1431C>T,... | DisGeNET | Detail |
The peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala polymorphism has been associ... | DisGeNET | Detail |
Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-... | DisGeNET | Detail |
The Pro12Ala PPARgamma polymorphism does not seem to be associated with BMI or metabolic syndrome pa... | DisGeNET | Detail |
The P12A variant in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene has been i... | DisGeNET | Detail |
Association between the peroxisome proliferator-activated receptor gamma Pro12Ala variant and haplot... | DisGeNET | Detail |
In this study, we evaluated the association between colorectal cancer and specific tumor mutations a... | DisGeNET | Detail |
Our findings suggest that Pro12Ala PPAR-gamma gene polymorphism may be protective against IR and mig... | DisGeNET | Detail |
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma 2 gene is suggeste... | DisGeNET | Detail |
These results suggest that in the Taiwanese, the Pro12Ala PPARgamma2 gene variant may contribute to ... | DisGeNET | Detail |
Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart dise... | DisGeNET | Detail |
The peroxisome proliferator activated receptor gamma Pro12Ala polymorphism is associated with a lowe... | DisGeNET | Detail |
We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-... | DisGeNET | Detail |
Four of the nine SNPs revealed a significant association with T2D; PPARG2 (Pro12Ala) [odds ratio (OR... | DisGeNET | Detail |
Lack of an association between peroxisome proliferator-activated receptor-gamma gene Pro12Ala polymo... | DisGeNET | Detail |
Evidence for interaction between PPARG Pro12Ala and PPARGC1A Gly482Ser polymorphisms in determining ... | DisGeNET | Detail |
This meta-analysis suggests that the Ala allele of the PPARgamma P12A polymorphism might be a protec... | DisGeNET | Detail |
The alanine allele of P12A polymorphism in PPARG gene in a few studies has been associated with a re... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pedi... | DisGeNET | Detail |
The data suggest a contribution of the Pro12Ala polymorphism of PPARgamma to genetic susceptibility ... | DisGeNET | Detail |
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over... | DisGeNET | Detail |
Beta3AR Trp64Arg and PPARgamma2 Pro12Ala polymorphisms might be associated with insulin resistance a... | DisGeNET | Detail |
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... | DisGeNET | Detail |
There was a significant interaction between the -200A>C IGFBP3 polymorphism and the Pro12Ala PPAR... | DisGeNET | Detail |
The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. | DisGeNET | Detail |
Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: ho... | DisGeNET | Detail |
The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated receptor γ (PPARγ) have be... | DisGeNET | Detail |
We have studied the association between single nucleotide polymorphisms in the interleukin (IL)-6 (-... | DisGeNET | Detail |
Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabetes mellitus on HbA1c ... | DisGeNET | Detail |
For rectal cancer there was a significant interaction between the Bsm1/polyA polymorphisms (p = 0.00... | DisGeNET | Detail |
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... | DisGeNET | Detail |
Is it time to conduct a hypothesis-driven large-scale exercise training intervention trial based on ... | DisGeNET | Detail |
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with inc... | DisGeNET | Detail |
The association of non-synonymous substitution polymorphism rs1801282 (c.34C>G, p.Pro12Ala) in ex... | DisGeNET | Detail |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are sugg... | DisGeNET | Detail |
A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associate... | DisGeNET | Detail |
The peroxisome proliferator-activated receptor gamma 2 Pro12Ala mutation is associated with early on... | DisGeNET | Detail |
PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. | DisGeNET | Detail |
Pro12Ala sequence variant of the PPARG gene is associated with postprandial hypertriglyceridemia in ... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associated with nephropath... | DisGeNET | Detail |
Nevertheless, prospectively designed cohort studies are needed to further investigate gene-gene and ... | DisGeNET | Detail |
These observations suggest that Pro12Ala (rs1801282), a coding variant in the PPARG gene, is associa... | DisGeNET | Detail |
The proline allele at PPARG P12A increases risk for diabetes in persons with impaired glucose tolera... | DisGeNET | Detail |
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... | DisGeNET | Detail |
The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator-Activated Receptor ... | DisGeNET | Detail |
Hence, our aim was to develop a low-cost method for the validation of PPARG (Pro12Ala, CCA>GCA) S... | DisGeNET | Detail |
In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotype have greater odds ... | DisGeNET | Detail |
Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral ... | DisGeNET | Detail |
No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery disease in Korean su... | DisGeNET | Detail |
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes a... | DisGeNET | Detail |
The frequencies of 2 common polymorphisms of the PPARgamma gene, Pro12Ala single nucleotide polymorp... | DisGeNET | Detail |
The study suggests that Pro12Ala PPARgamma polymorphism is associated with gastric adenocarcinoma an... | DisGeNET | Detail |
Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARgamma gene and co... | DisGeNET | Detail |
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obes... | DisGeNET | Detail |
The aim was to investigate if the polymorphism PPARgamma2 Pro12Ala, which encodes a less efficient t... | DisGeNET | Detail |
The other polymorphisms studied were not significantly associated with gestational diabetes mellitus... | DisGeNET | Detail |
The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma (PPARG) gene in re... | DisGeNET | Detail |
Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits... | DisGeNET | Detail |
Compared with first-degree relatives of PCOS subjects with the Pro12Pro polymorphism of PPAR-gamma, ... | DisGeNET | Detail |
Together, these results showed that PPARG Pro12Ala and PPARGC1A Gly482Ser variants are associated, a... | DisGeNET | Detail |
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is... | DisGeNET | Detail |
The data suggest a contribution of the Pro12Ala polymorphism of PPARgamma to genetic susceptibility ... | DisGeNET | Detail |
In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegregate with lipodystro... | DisGeNET | Detail |
Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism is associated with the suscep... | DisGeNET | Detail |
The Pro12Ala polymorphism of the gene for peroxisome proliferator activated receptor-gamma is associ... | DisGeNET | Detail |
The Pro(12)Ala (P12A) variant of exon B of the peroxisome proliferator-activated receptor gamma(2) (... | DisGeNET | Detail |
Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala poly... | DisGeNET | Detail |
We conclude that PPARg2 Pro12Ala polymorphisms are associated with increased risk for myocardial inf... | DisGeNET | Detail |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) has been ... | DisGeNET | Detail |
The authors highlight these challenges and biases using an illustrative example: meta-analysis of in... | DisGeNET | Detail |
No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery disease in Korean su... | DisGeNET | Detail |
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) gene and ... | DisGeNET | Detail |
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNF... | DisGeNET | Detail |
Prevalence of the Pro12Ala missense mutation in the PPARG2 gene in Kuwaiti patients with primary kne... | DisGeNET | Detail |
Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial c... | DisGeNET | Detail |
We suggest that Pro12Ala polymorphism of the PPAR-gamma gene may be a modifier of insulin resistance... | DisGeNET | Detail |
There was a significant interaction between the -200A>C IGFBP3 polymorphism and the Pro12Ala PPAR... | DisGeNET | Detail |
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obes... | DisGeNET | Detail |
PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pr... | DisGeNET | Detail |
The present study demonstrates that the AA genotype of the Gly482Ser polymorphism in the PPARGC1 gen... | DisGeNET | Detail |
Association between the Pro12Ala polymorphism of PPAR-γ gene and the polycystic ovary syndrome: a me... | DisGeNET | Detail |
Our objective was to search for differences in genotypes of peroxisome proliferator-activated recept... | DisGeNET | Detail |
A marginally significant increased risk of breast cancer was observed among women homozygous for the... | DisGeNET | Detail |
The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease. | DisGeNET | Detail |
In the group of participants with PPARγ Pro12Ala or Ala12Ala genotypes, those with the LPL Pvu (-/+)... | DisGeNET | Detail |
Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Ch... | DisGeNET | Detail |
Association between the peroxisome proliferator-activated receptor gamma Pro12Ala variant and haplot... | DisGeNET | Detail |
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A an... | DisGeNET | Detail |
PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes. | DisGeNET | Detail |
This study has shown that both Pro12Ala and His447His polymorphisms of PPAR-gamma are associated wit... | DisGeNET | Detail |
The single nucleotide polymorphisms (SNPs) of the above genes, such as GNB3-C825T, ADRB3-Trp64Arg, U... | DisGeNET | Detail |
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), I... | DisGeNET | Detail |
Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be associated with decrease... | DisGeNET | Detail |
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and res... | DisGeNET | Detail |
We examined the relationship between PPARG2 P12A and CHD risk in women (Nurses' Health Study) and me... | DisGeNET | Detail |
In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma polymorphism and bo... | DisGeNET | Detail |
We conclude that P12A and C161T polymorphisms of the PPAR-gamma gene are important predictors of car... | DisGeNET | Detail |
The protective role of the Ala allele in the Pro12Ala polymorphism of PPARγ on type 2 diabetes has b... | DisGeNET | Detail |
Two PPARg common polymorphisms, Pro12Ala and 161C>T, have been found to be associated with cardio... | DisGeNET | Detail |
In this study we evaluated the association between the Pro12Ala (P12A) PPARgamma polymorphism and bo... | DisGeNET | Detail |
The Pro12Ala and C161T polymorphisms in peroxisome proliferator-activated receptor γ (PPARγ) have be... | DisGeNET | Detail |
Association between the Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma 2 ... | DisGeNET | Detail |
The Pro12Ala polymorphism in exon B of peroxisome proliferator-activated receptor gamma 2 (PPAR gamm... | DisGeNET | Detail |
In the group with ACE DD genotype, those with PPARγ Pro12Ala or Ala12Ala genotype have greater odds ... | DisGeNET | Detail |
Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has be... | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs1805192 dbSNP
- Genome
- hg19
- Position
- chr3:12,421,238-12,421,238
- Variant Type
- snv
- Reference Allele
- C
- Alternative Allele
- G
Genome browser