chr3:32951644:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr3:32,993,136-32,997,841 |
| hg38 | chr3:32,951,644-32,956,349 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | Cardiomyopathy, Dilated | NA | BeFree | Detail | |
| 0.122 | celiac disease | NA | CTD_human,GAD | Detail | |
| 0.120 | brain ischemia | NA | CTD_human | Detail | |
| <0.001 | Chancroids | NA | BeFree | Detail | |
| 0.005 | Dermatitis, Atopic | NA | BeFree,LHGDN | Detail | |
| <0.001 | contact dermatitis | NA | BeFree | Detail | |
| <0.001 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree | Detail | |
| 0.002 | Eczema | NA | BeFree | Detail | |
| <0.001 | Eosinophilia | NA | BeFree | Detail | |
| <0.001 | Exanthema | NA | BeFree | Detail | |
| 0.120 | Glioma | NA | CTD_human | Detail | |
| <0.001 | glomerulonephritis | NA | BeFree | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| <0.001 | Hodgkin Disease | Moreover, when a CCR4(+) Hodgkin's lymphoma cell line was inoculated s.c. into h... | BeFree | 25712215 | Detail |
| <0.001 | Hydroa Vacciniforme | Interestingly, CCR4 was positive in 5 of 5 patients with hydroa vacciniforme, a ... | BeFree | 25117294 | Detail |
| <0.001 | Immune System Diseases | NA | BeFree | Detail | |
| 0.004 | Leukemia, T-Cell | NA | BeFree,LHGDN | Detail | |
| 0.136 | Adult T-Cell Lymphoma/Leukemia | Recently, the FDA has approved four drugs for patients with relapsed/refractory ... | BeFree,CTD_human,LHGDN | 25320373 | Detail |
| 0.136 | Adult T-Cell Lymphoma/Leukemia | Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma. | BeFree,CTD_human,LHGDN | 25488980 | Detail |
| 0.136 | Adult T-Cell Lymphoma/Leukemia | Furthermore, the anti-CCR4 monoclonal antibody mogamulizumab has been shown to h... | BeFree,CTD_human,LHGDN | 25613789 | Detail |
| 0.120 | Liver neoplasms | NA | CTD_human | Detail | |
| 0.003 | Lupus Erythematosus, Cutaneous | NA | LHGDN | Detail | |
| <0.001 | Lupus Erythematosus, Systemic | NA | BeFree | Detail | |
| 0.003 | lymphoma | Mogamulizumab induced antibody-dependent cellular cytotoxicity (ADCC) activity a... | BeFree,LHGDN | 25117294 | Detail |
| <0.001 | Lymphoproliferative Disorders | Anti-CCR4 monoclonal antibody mogamulizumab for the treatment of EBV-associated ... | BeFree | 25117294 | Detail |
| <0.001 | Malignant neoplasm of stomach | Aberrant CCR4 expression is involved in tumor invasion of lymph node-negative hu... | BeFree | 25790118 | Detail |
| <0.001 | melanoma | Mutually exclusive mutations of other members of the CCR4-NOT complex were found... | BeFree | 25544760 | Detail |
| <0.001 | multiple sclerosis | NA | BeFree | Detail | |
| <0.001 | myasthenia gravis | The two chemokines were mainly detected around medullary Hassall's corpuscles (H... | BeFree | 24397961 | Detail |
| <0.001 | mycosis fungoides | TOX and CCR4 messenger RNA (mRNA) levels in lesional skin of MF/SS were also exa... | BeFree | 25216799 | Detail |
| <0.001 | Neoplasm Metastasis | HNSCC with high expression of Myo1b and chemokine receptor 4 (CCR4), another met... | BeFree | 25421751 | Detail |
| <0.001 | nervous system disorder | NA | BeFree | Detail | |
| <0.001 | Degenerative polyarthritis | NA | BeFree | Detail | |
| <0.001 | pleurisy | NA | BeFree | Detail | |
| <0.001 | psoriasis | NA | BeFree | Detail | |
| 0.080 | pulmonary fibrosis | NA | RGD | Detail | |
| <0.001 | Respiratory Syncytial Virus Infections | Higher percentages of CCR4+ CD4 TEM cells in acute RSV infection were accompanie... | BeFree | 25013801 | Detail |
| <0.001 | Rheumatism | NA | BeFree | Detail | |
| <0.001 | Sarcoidosis, Pulmonary | NA | BeFree | Detail | |
| 0.121 | Sezary syndrome | TOX and CCR4 messenger RNA (mRNA) levels in lesional skin of MF/SS were also exa... | BeFree,CTD_human | 25216799 | Detail |
| <0.001 | Trisomy | NA | BeFree | Detail | |
| <0.001 | pleural tuberculosis | NA | BeFree | Detail | |
| <0.001 | Virus Diseases | Higher percentages of CCR4+ CD4 TEM cells in acute RSV infection were accompanie... | BeFree | 25013801 | Detail |
| 0.004 | Lymphoma, T-Cell, Cutaneous | Mogamulizumab reduces levels of CCR4(+) malignant T cells and also CCR4(+) Tregs... | BeFree,LHGDN | 25376389 | Detail |
| 0.003 | peripheral T-cell lymphoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Epstein-Barr Virus Infections | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of lung | NA | BeFree | Detail | |
| <0.001 | Tumor Progression | Our data suggest that the aberrant CCR4 expression is involved in tumor invasion... | BeFree | 25790118 | Detail |
| <0.001 | Lymphomatoid Papulosis | NA | BeFree | Detail | |
| <0.001 | Psoriasis vulgaris | NA | BeFree | Detail | |
| <0.001 | Opsoclonus-myoclonus syndrome | NA | BeFree | Detail | |
| 0.002 | Dermatitis and eczema | NA | GAD | Detail | |
| <0.001 | X-Linked Lymphoproliferative Disorder | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of lymph node | HNSCC with high expression of Myo1b and chemokine receptor 4 (CCR4), another met... | BeFree | 25421751 | Detail |
| <0.001 | stomach carcinoma | Aberrant CCR4 expression is involved in tumor invasion of lymph node-negative hu... | BeFree | 25790118 | Detail |
| <0.001 | airway disease | NA | BeFree | Detail | |
| <0.001 | Hereditary allergy | NA | BeFree | Detail | |
| <0.001 | latent infection | NA | BeFree | Detail | |
| <0.001 | Eosinophilic disorder | NA | BeFree | Detail | |
| <0.001 | Anaplastic large cell lymphoma, ALK negative | NA | BeFree | Detail | |
| <0.001 | Refractory Neoplasm | NA | BeFree | Detail | |
| 0.003 | Mammary Neoplasms | NA | BeFree,LHGDN | Detail | |
| <0.001 | Tumor Immunity | NA | BeFree | Detail | |
| <0.001 | Xenograft Model | NA | BeFree | Detail | |
| <0.001 | Disorder characterized by eosinophilia | NA | BeFree | Detail | |
| <0.001 | Lymphoma, Extranodal NK-T-Cell | NA | BeFree | Detail | |
| 0.002 | liver carcinoma | NA | GAD | Detail | |
| <0.001 | Juvenile arthritis | NA | BeFree | Detail | |
| <0.001 | Allergic disposition | NA | BeFree | Detail | |
| <0.001 | juvenile rheumatoid arthritis | NA | BeFree | Detail | |
| <0.001 | Airway Obstruction | NA | BeFree | Detail | |
| <0.001 | rheumatoid arthritis | NA | BeFree | Detail | |
| 0.082 | asthma | NA | BeFree,RGD | Detail | |
| <0.001 | Autoimmune Diseases | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Moreover, when a CCR4(+) Hodgkin's lymphoma cell line was inoculated s.c. into hu-HSC NOG-IL-2 Tg, t... | DisGeNET | Detail |
| Interestingly, CCR4 was positive in 5 of 5 patients with hydroa vacciniforme, a photodermatosis caus... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Recently, the FDA has approved four drugs for patients with relapsed/refractory PTCL over the past 5... | DisGeNET | Detail |
| Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma. | DisGeNET | Detail |
| Furthermore, the anti-CCR4 monoclonal antibody mogamulizumab has been shown to have marked cytotoxic... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Mogamulizumab induced antibody-dependent cellular cytotoxicity (ADCC) activity against CCR4-positive... | DisGeNET | Detail |
| Anti-CCR4 monoclonal antibody mogamulizumab for the treatment of EBV-associated T- and NK-cell lymph... | DisGeNET | Detail |
| Aberrant CCR4 expression is involved in tumor invasion of lymph node-negative human gastric cancer. | DisGeNET | Detail |
| Mutually exclusive mutations of other members of the CCR4-NOT complex were found in ~20% of the TCGA... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The two chemokines were mainly detected around medullary Hassall's corpuscles (HCs), co-localizing w... | DisGeNET | Detail |
| TOX and CCR4 messenger RNA (mRNA) levels in lesional skin of MF/SS were also examined. | DisGeNET | Detail |
| HNSCC with high expression of Myo1b and chemokine receptor 4 (CCR4), another metastasis-associated m... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Higher percentages of CCR4+ CD4 TEM cells in acute RSV infection were accompanied with higher percen... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| TOX and CCR4 messenger RNA (mRNA) levels in lesional skin of MF/SS were also examined. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Higher percentages of CCR4+ CD4 TEM cells in acute RSV infection were accompanied with higher percen... | DisGeNET | Detail |
| Mogamulizumab reduces levels of CCR4(+) malignant T cells and also CCR4(+) Tregs in patients with CT... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our data suggest that the aberrant CCR4 expression is involved in tumor invasion of pN0 GC and, conc... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| HNSCC with high expression of Myo1b and chemokine receptor 4 (CCR4), another metastasis-associated m... | DisGeNET | Detail |
| Aberrant CCR4 expression is involved in tumor invasion of lymph node-negative human gastric cancer. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- Genome
- hg38
- Position
- chr3:32,951,644-32,956,349
- Variant Type
- snv
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