Annotation Detail
Information
- Associated Genes
- CCR4
- Associated Variants
-
CCR4 MUTATION
CCR4 MUTATION - Associated Disease
- Lymphoma, T-Cell, Cutaneous
- Source Database
- DisGeNET
- Description
- Mogamulizumab reduces levels of CCR4(+) malignant T cells and also CCR4(+) Tregs in patients with CTCL, which may in turn improve immune profiles.Clin Cancer Res; 21(2); 274-85.©2014 AACR.
- Pubmed
- 25376389
- Section of the abstract supporting the evidence
- CONCLUSIONS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 14
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00408155960286869
Drugs