Annotation Detail

Information
Associated Genes
CCR4
Associated Variants
CCR4 MUTATION
CCR4 MUTATION
Associated Disease
myasthenia gravis
Source Database
DisGeNET
Description
The two chemokines were mainly detected around medullary Hassall's corpuscles (HCs), co-localizing with TLR4(+) thymic epithelial cells (TECs) and CCR4(+) dendritic cells (DCs), that were present in higher number in MG thymuses compared to controls.
Pubmed
24397961
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs