Annotation Detail

Information
Associated Genes
CCR4
Associated Variants
CCR4 MUTATION
CCR4 MUTATION
Associated Disease
lymphoma
Source Database
DisGeNET
Description
Mogamulizumab induced antibody-dependent cellular cytotoxicity (ADCC) activity against CCR4-positive cell lines, and inhibited the growth of EBV-positive NK-cell lymphomas in a murine xenograft model.
Pubmed
25117294
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00299579211454747
Drugs