chr11:57365036:> Detail (hg19)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr11:57,365,036-57,386,632 |
hg38 | chr11:57,597,563-57,619,159 |
HGVS
Type | Transcript | Protein |
---|---|---|
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.002 | Choroid Diseases | NA | GAD | Detail | |
<0.001 | Congenital chromosomal disease | NA | BeFree | Detail | |
<0.001 | Exanthema | NA | BeFree | Detail | |
<0.001 | Guillain-Barre syndrome | NA | BeFree | Detail | |
0.163 | Angioedemas, Hereditary | The inherited deficiency of C1-inhibitor (C1-INH), which can be quantitative (ty... | BeFree,CTD_human,LHGDN | 24552232 | Detail |
0.163 | Angioedemas, Hereditary | Expression of the SERPING1 gene is not regulated by promoter hypermethylation in... | BeFree,CTD_human,LHGDN | 25053016 | Detail |
0.163 | Angioedemas, Hereditary | The FXII-HAE is associated with modifiers, for example kinin catabolism enzymes,... | BeFree,CTD_human,LHGDN | 25134986 | Detail |
0.163 | Angioedemas, Hereditary | In conclusion, we demonstrate that C1-inh polymers are present in the plasma of ... | BeFree,CTD_human,LHGDN | 25369003 | Detail |
0.163 | Angioedemas, Hereditary | However, since the first identification of autosomal recessive (AR), X-linked re... | BeFree,CTD_human,LHGDN | 25645939 | Detail |
0.163 | Angioedemas, Hereditary | Hereditary angioedema (HAE) is a rare genetic disease caused by a deficiency in ... | BeFree,CTD_human,LHGDN | 25689810 | Detail |
0.163 | Angioedemas, Hereditary | Hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE type I) or dysf... | BeFree,CTD_human,LHGDN | 25758562 | Detail |
0.163 | Angioedemas, Hereditary | We report for the first time in Brazil a mutation in the F12 gene as a likely ca... | BeFree,CTD_human,LHGDN | 25790805 | Detail |
0.163 | Angioedemas, Hereditary | The C1-inh polymers might play a role in the pathophysiology of HAE, but several... | BeFree,CTD_human,LHGDN | 25800206 | Detail |
0.163 | Angioedemas, Hereditary | HAE type I occurred in 99 patients (57.9%), HAE type II occurred in 9 patients (... | BeFree,CTD_human,LHGDN | 25872948 | Detail |
0.003 | Inflammation | NA | LHGDN | Detail | |
0.120 | influenza | NA | CTD_human | Detail | |
0.001 | Liver neoplasms | NA | BeFree | Detail | |
<0.001 | Lupus Erythematosus, Systemic | NA | BeFree | Detail | |
0.120 | lupus nephritis | NA | CTD_human | Detail | |
0.002 | Lymphoma, Non-Hodgkin | NA | GAD | Detail | |
<0.001 | macular degeneration | Therefore, the results of our study and meta-analysis suggest that SERPING1 is n... | BeFree | 25800435 | Detail |
0.003 | Meningococcal Infections | NA | BeFree,GAD | Detail | |
<0.001 | myocardial infarction | NA | BeFree | Detail | |
<0.001 | neuroblastoma | NA | BeFree | Detail | |
0.002 | otitis media | NA | GAD | Detail | |
<0.001 | pulmonary emphysema | NA | BeFree | Detail | |
<0.001 | Septicemia | NA | BeFree | Detail | |
0.001 | urticaria | Hereditary angioedema (HAE) is a rare genetic disease caused by a deficiency in ... | BeFree | 25689810 | Detail |
0.001 | urticaria | Diagnosis of C1-INH-HAE was based on family and/or personal history of recurrent... | BeFree | 25758562 | Detail |
<0.001 | anterior uveitis | NA | BeFree | Detail | |
0.003 | vasculitis | NA | BeFree,LHGDN | Detail | |
<0.001 | Virus Diseases | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma of lung | NA | BeFree | Detail | |
<0.001 | pelvic inflammatory disease | However, since the first identification of autosomal recessive (AR), X-linked re... | BeFree | 25645939 | Detail |
<0.001 | Sepsis | NA | BeFree | Detail | |
<0.001 | chronic urticaria | NA | BeFree | Detail | |
0.080 | Pancreatitis, Acute Necrotizing | NA | RGD | Detail | |
<0.001 | Exudative age-related macular degeneration | NA | BeFree | Detail | |
<0.001 | Restenosis | NA | BeFree | Detail | |
<0.001 | Acute edema | NA | BeFree | Detail | |
<0.001 | Senile Plaques | NA | BeFree | Detail | |
0.120 | Hereditary C1 esterase inhibitor deficiency - deficient factor | NA | ORPHANET | Detail | |
0.120 | Hereditary C1 esterase inhibitor deficiency - dysfunctional factor | NA | ORPHANET | Detail | |
<0.001 | neuropathy | NA | BeFree | Detail | |
<0.001 | Oropharynx (excludes nasopharynx) | NA | BeFree | Detail | |
0.002 | Choroidal Neovascularization | NA | GAD | Detail | |
<0.001 | Central neuroblastoma | NA | BeFree | Detail | |
<0.001 | Acute anterior uveitis | NA | BeFree | Detail | |
<0.001 | allergic symptom | NA | BeFree | Detail | |
0.002 | Malignant neoplasm of ovary | NA | GAD | Detail | |
0.120 | Complement Component 4, Partial Deficiency Of | NA | CTD_human | Detail | |
<0.001 | Vasculitic neuropathy | NA | BeFree | Detail | |
0.001 | liver carcinoma | NA | BeFree | Detail | |
0.120 | Hereditary Angioedema Types I and II | NA | CTD_human | Detail | |
0.361 | hereditary angioedema type I | SERPING1 mutations causing Hereditary Angioedema type I (HAE-I) due to C1-Inhibi... | BeFree,CLINVAR,ORPHANET,UNIPROT | 25053016 | Detail |
0.122 | acquired angioedema | NA | BeFree,CTD_human | Detail | |
<0.001 | Plaque, Amyloid | NA | BeFree | Detail | |
<0.001 | Abdominal Pain | We report for the first time in Brazil a mutation in the F12 gene as a likely ca... | BeFree | 25790805 | Detail |
<0.001 | Airway Obstruction | NA | BeFree | Detail | |
<0.001 | Alzheimer's disease | NA | BeFree | Detail | |
<0.001 | asthma | NA | BeFree | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The inherited deficiency of C1-inhibitor (C1-INH), which can be quantitative (type I) or qualitative... | DisGeNET | Detail |
Expression of the SERPING1 gene is not regulated by promoter hypermethylation in peripheral blood mo... | DisGeNET | Detail |
The FXII-HAE is associated with modifiers, for example kinin catabolism enzymes, ACE and CPN, differ... | DisGeNET | Detail |
In conclusion, we demonstrate that C1-inh polymers are present in the plasma of a subgroup of HAE ty... | DisGeNET | Detail |
However, since the first identification of autosomal recessive (AR), X-linked recessive (XR) and AD ... | DisGeNET | Detail |
Hereditary angioedema (HAE) is a rare genetic disease caused by a deficiency in functional C1-estera... | DisGeNET | Detail |
Hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE type I) or dysfunction (C1-INH-HAE ... | DisGeNET | Detail |
We report for the first time in Brazil a mutation in the F12 gene as a likely cause of HAE with norm... | DisGeNET | Detail |
The C1-inh polymers might play a role in the pathophysiology of HAE, but several diseases are charac... | DisGeNET | Detail |
HAE type I occurred in 99 patients (57.9%), HAE type II occurred in 9 patients (5.3%), HAE with norm... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Therefore, the results of our study and meta-analysis suggest that SERPING1 is not a major genetic c... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Hereditary angioedema (HAE) is a rare genetic disease caused by a deficiency in functional C1-estera... | DisGeNET | Detail |
Diagnosis of C1-INH-HAE was based on family and/or personal history of recurrent angioedema without ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
However, since the first identification of autosomal recessive (AR), X-linked recessive (XR) and AD ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
SERPING1 mutations causing Hereditary Angioedema type I (HAE-I) due to C1-Inhibitor (C1-INH) deficie... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
We report for the first time in Brazil a mutation in the F12 gene as a likely cause of HAE with norm... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- Genome
- hg19
- Position
- chr11:57,365,036-57,386,632
- Variant Type
- snv
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