Hereditary Angioedema Types I and II
Information
- Disease name
- Hereditary Angioedema Types I and II
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05047185 | Active, not recruiting | Phase 2 | Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II | April 19, 2022 | December 2026 |
| NCT01576523 | Completed | Phase 1/Phase 2 | A Study to Evaluate the Clinical Pharmacology and Safety of C1-esterase Inhibitor Administered by the Subcutaneous Route | April 2012 | December 2012 |
| NCT01760343 | Completed | Phase 1 | A Study to Evaluate the Safety and Pharmacokinetics of Two Formulations of C1-esterase Inhibitor | January 2013 | March 2013 |
| NCT01912456 | Completed | Phase 3 | A Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema | January 2014 | October 2015 |
| NCT02316353 | Completed | Phase 3 | A Study to Evaluate the Long-term Clinical Safety and Efficacy of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema | December 31, 2014 | September 21, 2017 |
| NCT04618211 | Completed | Phase 2 | Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema | February 3, 2021 | March 1, 2023 |
| NCT01467947 | Completed | Phase 4 | Postmarketing Immunogenicity Study in HAE Subjects Treated With Berinert | November 2011 | October 2014 |
| NCT05396105 | Recruiting | Phase 2/Phase 3 | Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema | December 28, 2022 | December 2024 |
| NCT06343779 | Recruiting | Phase 3 | Study of Oral Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema | February 26, 2024 | March 2026 |
| NCT01832896 | Withdrawn | Phase 2 | Study to Assess the Tolerability and Safety of Ecallantide in Children and Adolescents With Hereditary Angioedema | August 2013 | December 2017 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D056829