hereditary angioedema type I
Information
- Disease name
- hereditary angioedema type I
- Disease ID
- DOID:0080939
- Description
- "A hereditrary angioedema that has_material_basis_in heterozygous mutation in the C1 inhibitor gene (C1NH, SERPING1) on chromosome 11q." [url:https\://pubmed.ncbi.nlm.nih.gov/11161971/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05047185 | Active, not recruiting | Phase 2 | Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II | April 19, 2022 | December 2026 |
| NCT00119431 | Completed | Phase 2 | Kinetics, Efficacy and Safety of C1-Esteraseremmer-N | September 2005 | March 2006 |
| NCT03029728 | Completed | Biomarker for Hereditary AngioEdema Disease | August 20, 2018 | March 11, 2022 | |
| NCT04618211 | Completed | Phase 2 | Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema | February 3, 2021 | March 1, 2023 |
| NCT05396105 | Recruiting | Phase 2/Phase 3 | Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema | December 28, 2022 | December 2024 |
| NCT06343779 | Recruiting | Phase 3 | Study of Oral Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema | February 26, 2024 | March 2026 |
- Disase is a (Disease Ontology)
- DOID:14735
- Cross Reference ID (Disease Ontology)
- MIM:106100