ROS1 OVEREXPRESSION Detail (hg19) (ROS1)

Information

Genome

Assembly Position
hg19 chr6:117,608,516-117,747,105
hg38 chr6:117,287,353-117,425,942 
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Type Database ID Link
Gene MIM
HGNC
Ensembl
NCBI
Gene Cards
OncoKB
Type Database ID Link
Variant TogoVar
COSMIC
MONDO
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
[No Data.]
Annotation

Annotations

DescrptionSourceLinks
Antagonistic combinations with imexon included methotrexate MMMP Detail
Antagonistic combinations with imexon included itrinotecan MMMP Detail
Antagonistic combinations with imexon included doxorubicin MMMP Detail
Antagonistic combinations with imexon included mitoxantrone MMMP Detail
Antagonistic combinations with imexon included etoposide MMMP Detail
ET-743 is believed to act through formation of anion superoxide in proximity of DNA with consequent ... MMMP Detail
Elesclomol is believed to act by increasing reactive oxygen species (ROS) levels. This phase II RCT ... MMMP Detail
The consistent synergy seen for imexon and alkylating agents may relate to the sulfhydryl-lowering e... MMMP Detail
The marked synergy noted with pyrimidine-based antimetabolites was unexpected and may relate to the ... MMMP Detail
The consistent synergy seen for imexon and alkylating agents may relate to the sulfhydryl-lowering e... MMMP Detail
Docetaxel and Imexon synergically killed melanoma cells MMMP Detail
The marked synergy noted with pyrimidine-based antimetabolites was unexpected and may relate to the ... MMMP Detail
The marked synergy noted with pyrimidine-based antimetabolites was unexpected and may relate to the ... MMMP Detail
The consistent synergy seen for imexon and alkylating agents may relate to the sulfhydryl-lowering e... MMMP Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg19
Position
chr6:117,608,516-117,747,105
Variant Type
cnv
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