Annotation Detail
Information
- Associated Genes
- ROS1
- Associated Variants
- ROS1 OVEREXPRESSION
- Source Database
- MMMP
- Description
- Elesclomol is believed to act by increasing reactive oxygen species (ROS) levels. This phase II RCT showed an increased progression free survival (no increase in overall response rate or overall survival was demonstrated) that warrants further investigation according to the Authors
- MMMP State
- upregulated by
- MMMP Molecule
- ROS
- MMMP Molecule Alias
- Reactive oxygen species
- MMMP Modifier
- Elesclomol
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Paclitaxel
- MMMP Drug Alias
- Taxol
- MMMP Model
- 6
- MMMP Reference
- O'Day S, J Clin Oncol 2009, 27:5452-8
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Paclitaxel | Sensitivity | true |