Annotation Detail

Information
Associated Genes
ROS1
Associated Variants
ROS1 OVEREXPRESSION
Source Database
MMMP
Description
Antagonistic combinations with imexon included methotrexate
MMMP State
upregulated by
MMMP Molecule
ROS
MMMP Molecule Alias
Reactive oxygen species
MMMP Modifier
Imexon
MMMP Relationship
resistance to
MMMP Drug
Methotrexate
MMMP Drug Alias
MTX
MMMP Model
3
MMMP Reference
Scott J, Cancer Chemother Pharmacol 2007, 59:749-57
Drugs
Drug NameSensitivitySupported
MethotrexateResitance or Non-Reponsetrue