Annotation Detail
Information
- Associated Genes
- ROS1
- Associated Variants
- ROS1 OVEREXPRESSION
- Source Database
- MMMP
- Description
- The marked synergy noted with pyrimidine-based antimetabolites was unexpected and may relate to the induction of cell cycle arrest in S-phase
- MMMP State
- upregulated by
- MMMP Molecule
- ROS
- MMMP Molecule Alias
- Reactive oxygen species
- MMMP Modifier
- Imexon
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Gemcitabine
- MMMP Model
- 3
- MMMP Reference
- Scott J, Cancer Chemother Pharmacol 2007, 59:749-57
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Gemcitabine | Sensitivity | true |