chr14:105235686:> Detail (hg19) (AKT1)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr14:105,235,686-105,262,096 |
| hg38 | chr14:104,769,349-104,795,759 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| Wortmannin is a PI3K inhibitor (PI3K activates AKT by phosphorylation). Constitutive activation of A... | MMMP | Detail |
| Akt-DN: dominant negative AKT. Authors used different cell lines: one melanoma cell line with low AK... | MMMP | Detail |
| Perifosine is an AKT inhibitor. Metastatic melanoma. No objective response was observed. AKT express... | MMMP | Detail |
| Pretreatment pS6 levels correlated with sensitivity to the PI3K inhibitor, LY294002, whereas PI3K an... | MMMP | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- Genome
- hg19
- Position
- chr14:105,235,686-105,262,096
- Variant Type
- snv
Genome browser