Annotation Detail
Information
- Associated Genes
- AKT1
- Associated Variants
- AKT1 UNKNOWN
- Source Database
- MMMP
- Description
- Perifosine is an AKT inhibitor. Metastatic melanoma. No objective response was observed. AKT expression/activity was not determined. No preclinical data are available
- MMMP State
- uncharacterized
- MMMP Molecule
- AKT
- MMMP Molecule Alias
- PKB
- MMMP Relationship
- no relationship with
- MMMP Drug
- Perifosine
- MMMP Model
- 5
- MMMP Reference
- Ernst DS, Invest New Drugs 2005, 23:569-75
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Perifosine | Resitance or Non-Reponse | true |