Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF c.-1037C>T
TNF c.-488G>A
NC_000006.12:g.31575324G>A
TNF c.-1037C>T
TNF c.-488G>A
NC_000006.12:g.31575324G>A
Associated Disease
diabetic retinopathy
Source Database
DisGeNET
Description
In a case-control study, the -238G>A (rs361525), -308G>A (rs1800629), and -857C>T (rs1799724) polymorphisms of the TNF gene were genotyped in 745 outpatients with type 2 diabetes, including 331 subjects without DR, 246 with nonproliferative DR (NPDR), and 168 with proliferative DR (PDR).
Pubmed
25634985
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0243612120953607
Year of publication
2015
Drugs