Annotation Detail
Information
- Associated Genes
- IL1A
- Associated Variants
-
IL1A MUTATION
IL1A MUTATION
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
NC_000002.12:g.112837290A>G
TNF c.-488G>A
NC_000006.12:g.31575324G>A
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
NC_000002.12:g.112837290A>G
TNF c.-488G>A
NC_000006.12:g.31575324G>A - Associated Disease
- Chronic sinusitis
- Source Database
- DisGeNET
- Description
- To replicate and extend recent findings in a Turkish population of associations between chronic rhinosinusitis (CRS) with nasal polyposis and single-nucleotide polymorphisms (SNPs) in the IL1A (rs17561 and Ser114Ala), IL1B (rs16944), and TNF (rs361525 and rs1800629) genes.
- Pubmed
- 20157068
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2010
Drugs