chr15:74719300:A>G Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr15:75,011,641-75,011,641 View the variant detail on this assembly version. |
| hg38 | chr15:74,719,300-74,719,300 |
HGVS
[No Data.]
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
| JP | HGVD:[No Data.] |
| ToMMo:0.368 | |
| NCBN:[No Data.] | |
| NCBN(Hondo):[No Data.] | |
| NCBN(Ryukyu):[No Data.] | |
| East asia | ExAC:[No Data.] |
Prediction
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.001 | vascular disease occlusive | All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... | BeFree | 23107763 | Detail |
| 0.126 | Malignant neoplasm of lung | A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the G... | BeFree | 22525558 | Detail |
| 0.014 | Carcinoma of lung | A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the G... | BeFree | 22525558 | Detail |
| 0.047 | Carcinoma of lung | A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the G... | BeFree | 22525558 | Detail |
| 0.124 | Malignant neoplasm of lung | A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the G... | BeFree | 22525558 | Detail |
| 0.214 | Malignant neoplasm of lung | A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the G... | BeFree | 22525558 | Detail |
| 0.044 | Carcinoma of lung | A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the G... | BeFree | 22525558 | Detail |
| 0.337 | hyperhomocysteinemia | All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... | BeFree | 23107763 | Detail |
| <0.001 | hyperhomocysteinemia | All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... | BeFree | 23107763 | Detail |
| 0.146 | Homocysteinemia | All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... | BeFree | 23107763 | Detail |
| <0.001 | Homocysteinemia | All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... | BeFree | 23107763 | Detail |
| 0.044 | Malignant neoplasm of lung | CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... | BeFree | 22525558 | Detail |
| 0.007 | Carcinoma of lung | CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... | BeFree | 22525558 | Detail |
| 0.020 | Carcinoma of lung | CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... | BeFree | 22525558 | Detail |
| 0.092 | Malignant neoplasm of lung | CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... | BeFree | 22525558 | Detail |
| 0.100 | Malignant neoplasm of lung | CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... | BeFree | 22525558 | Detail |
| 0.005 | cervix carcinoma | Association of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) wi... | BeFree | 24657182 | Detail |
| <0.001 | Brain Neoplasms | The increased risk of brain tumors was evident for CYP1A1 rs2606345 (P = 0.0028;... | BeFree | 23661361 | Detail |
| 0.003 | Malignant tumor of cervix | Association of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) wi... | BeFree | 24657182 | Detail |
| 0.012 | Carcinoma of lung | CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI =... | BeFree | 22525558 | Detail |
| 0.039 | Esophageal Neoplasms | Genetic susceptibility to esophageal cancer due to CYP1A1 gene variant rs4646903... | BeFree | 25169514 | Detail |
| 0.005 | Carcinogenesis | We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymor... | BeFree | 23686565 | Detail |
| 0.002 | Carcinogenesis | We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymor... | BeFree | 23686565 | Detail |
| 0.038 | Malignant neoplasm of esophagus | Genetic susceptibility to esophageal cancer due to CYP1A1 gene variant rs4646903... | BeFree | 25169514 | Detail |
| 0.104 | Malignant neoplasm of breast | Results from this study suggest that rs4680 in the COMT gene and rs4646903 in th... | BeFree | 17429315 | Detail |
| 0.003 | Malignant tumor of cervix | An association with cervical cancer and high-grade dysplasia was found for the r... | BeFree | 21897271 | Detail |
| 0.005 | cervix carcinoma | An association with cervical cancer and high-grade dysplasia was found for the r... | BeFree | 21897271 | Detail |
| 0.001 | Lupus Erythematosus, Systemic | We investigated the relationship of the cytochrome P450 (CYP) 1A1 rs4646903 and ... | BeFree | 22217397 | Detail |
| 0.024 | breast carcinoma | Results from this study suggest that rs4680 in the COMT gene and rs4646903 in th... | BeFree | 17429315 | Detail |
| 0.101 | Malignant neoplasm of breast | Results from this study suggest that rs4680 in the COMT gene and rs4646903 in th... | BeFree | 17429315 | Detail |
| 0.009 | Carcinogenesis | We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymor... | BeFree | 23686565 | Detail |
| 0.044 | Carcinoma of lung | The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to ... | BeFree | 19650794 | Detail |
| 0.002 | Coronary Arteriosclerosis | The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to ... | BeFree | 19650794 | Detail |
| 0.002 | Coronary heart disease | The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to ... | BeFree | 19650794 | Detail |
| 0.007 | esophageal carcinoma | Genetic susceptibility to esophageal cancer due to CYP1A1 gene variant rs4646903... | BeFree | 25169514 | Detail |
| 0.003 | Helicobacter pylori infection | We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymor... | BeFree | 23686565 | Detail |
| 0.017 | coronary artery disease | rs4769874 (ALOX5AP), rs854560 (PON1), and rs4646903 (CYP1A1 MspI polymorphism) a... | BeFree | 25902778 | Detail |
| 0.124 | Malignant neoplasm of lung | The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to ... | BeFree | 19650794 | Detail |
| 0.002 | Lupus Erythematosus, Systemic | We investigated the relationship of the cytochrome P450 (CYP) 1A1 rs4646903 and ... | BeFree | 22217397 | Detail |
| 0.021 | breast carcinoma | Results from this study suggest that rs4680 in the COMT gene and rs4646903 in th... | BeFree | 17429315 | Detail |
| 0.006 | Leukoplakia | We examined the association of 13 variants in eight genes (rs4646903, rs2031920,... | BeFree | 21741876 | Detail |
| 0.006 | Leukoplakia | We examined the association of 13 variants in eight genes (rs4646903, rs2031920,... | BeFree | 21741876 | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... | DisGeNET | Detail |
| A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the GSTM1 deletion polymo... | DisGeNET | Detail |
| A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the GSTM1 deletion polymo... | DisGeNET | Detail |
| A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the GSTM1 deletion polymo... | DisGeNET | Detail |
| A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the GSTM1 deletion polymo... | DisGeNET | Detail |
| A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the GSTM1 deletion polymo... | DisGeNET | Detail |
| A pertinent combination of multiple at-risk genotypes of CYP1A1 rs4646903, the GSTM1 deletion polymo... | DisGeNET | Detail |
| All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... | DisGeNET | Detail |
| All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... | DisGeNET | Detail |
| All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... | DisGeNET | Detail |
| All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... | DisGeNET | Detail |
| CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... | DisGeNET | Detail |
| CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... | DisGeNET | Detail |
| CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... | DisGeNET | Detail |
| CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... | DisGeNET | Detail |
| CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... | DisGeNET | Detail |
| Association of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) with cervical cancer i... | DisGeNET | Detail |
| The increased risk of brain tumors was evident for CYP1A1 rs2606345 (P = 0.0028; OR = 2.06; 95 % CI,... | DisGeNET | Detail |
| Association of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) with cervical cancer i... | DisGeNET | Detail |
| CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GST... | DisGeNET | Detail |
| Genetic susceptibility to esophageal cancer due to CYP1A1 gene variant rs4646903 in tobacco addicted... | DisGeNET | Detail |
| We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymorphisms in associatio... | DisGeNET | Detail |
| We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymorphisms in associatio... | DisGeNET | Detail |
| Genetic susceptibility to esophageal cancer due to CYP1A1 gene variant rs4646903 in tobacco addicted... | DisGeNET | Detail |
| Results from this study suggest that rs4680 in the COMT gene and rs4646903 in the CYP1A1 gene may be... | DisGeNET | Detail |
| An association with cervical cancer and high-grade dysplasia was found for the rare homozygous CC ge... | DisGeNET | Detail |
| An association with cervical cancer and high-grade dysplasia was found for the rare homozygous CC ge... | DisGeNET | Detail |
| We investigated the relationship of the cytochrome P450 (CYP) 1A1 rs4646903 and glutathione S-transf... | DisGeNET | Detail |
| Results from this study suggest that rs4680 in the COMT gene and rs4646903 in the CYP1A1 gene may be... | DisGeNET | Detail |
| Results from this study suggest that rs4680 in the COMT gene and rs4646903 in the CYP1A1 gene may be... | DisGeNET | Detail |
| We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymorphisms in associatio... | DisGeNET | Detail |
| The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of c... | DisGeNET | Detail |
| The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of c... | DisGeNET | Detail |
| The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of c... | DisGeNET | Detail |
| Genetic susceptibility to esophageal cancer due to CYP1A1 gene variant rs4646903 in tobacco addicted... | DisGeNET | Detail |
| We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymorphisms in associatio... | DisGeNET | Detail |
| rs4769874 (ALOX5AP), rs854560 (PON1), and rs4646903 (CYP1A1 MspI polymorphism) are significantly ass... | DisGeNET | Detail |
| The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of c... | DisGeNET | Detail |
| We investigated the relationship of the cytochrome P450 (CYP) 1A1 rs4646903 and glutathione S-transf... | DisGeNET | Detail |
| Results from this study suggest that rs4680 in the COMT gene and rs4646903 in the CYP1A1 gene may be... | DisGeNET | Detail |
| We examined the association of 13 variants in eight genes (rs4646903, rs2031920, rs3813867, GSTM1 nu... | DisGeNET | Detail |
| We examined the association of 13 variants in eight genes (rs4646903, rs2031920, rs3813867, GSTM1 nu... | DisGeNET | Detail |
- Gene
- -
- dbSNP
- rs4646903 dbSNP
- Genome
- hg38
- Position
- chr15:74,719,300-74,719,300
- Variant Type
- snv
- Reference Allele
- A
- Alternative Allele
- G
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs4646903
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.3675
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 6158
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16758
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