AURKA OVEREXPRESSION Detail (hg19) (AURKA)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr20:54,944,446-54,967,393 |
| hg38 | chr20:56,369,390-56,392,337 View the variant detail on this assembly version. |
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
| Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| ovarian serous carcinoma | Platinum Compound | B |
Predictive
|
Supports
|
Resistance |
N/A
|
3 | 27209210 | Detail |
| cervical adenocarcinoma | Paclitaxel | D |
Predictive
|
Supports
|
Resistance | Somatic | 3 | 12559175 | Detail |
| lung non-small cell carcinoma | Cisplatin | B |
Predictive
|
Supports
|
Resistance |
N/A
|
4 | 25082261 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| A study of 41 patients with high-grade ovarian serous carcinoma found that high expression levels of... | CIViC Evidence | Detail |
| In the cervial andenocarcinoma cell line HeLa, when AURK-A was overexpressed, the cells were resista... | CIViC Evidence | Detail |
| High levels of Aurora-A expression (retrospectively assessed by IHC in 102 NSCLC patients) predicted... | CIViC Evidence | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- AURKA
- Genome
- hg19
- Position
- chr20:54,944,446-54,967,393
- Variant Type
- cnv
- Variant (CIViC) (CIViC Variant)
- OVEREXPRESSION
- Transcript 1 (CIViC Variant)
- ENST00000395913.3
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/181
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