Carmustine
Information
- Drug Name
- Carmustine
- Description
- Entry(CIViC)
- 1
CIViC
Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
---|---|---|---|---|---|---|---|---|---|
glioblastoma | MGMT PROMOTER METHYLATION MGMT PROMOTER METHYLATION | B |
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Sensitivity/Response | Somatic | 4 | 11070098 | Detail |
Annotation
Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
---|---|---|---|---|---|---|
MGMT promoter methylation has been shown to confer... | MGMT | MGMT PROMOTER METHYLATION MGMT PROMOTER METHYLATION | Sensitivity | true | CIViC Evidence | detail |
O(6)-methylguanine DNA-methyltransferase (MGMT) ov... | MGMT | MGMT OVEREXPRESSION | Resitance or Non-Reponse | true | MMMP | detail |
Combination of tamoxifen with CDDP was highly syne... | ESR1 | ESR1 UNDEREXPRESSION | Resitance or Non-Reponse | true | MMMP | detail |
NCT ID | Status | Phase | Summary | Start date | Completion date |
---|---|---|---|---|---|
NCT01511562 | Active, not recruiting | Phase 2 | Combination Chemotherapy With or Without Autologous Stem Cell Transplant in Treating Patients With Central Nervous System B-Cell Lymphoma | September 2012 | |
NCT00716066 | Active, not recruiting | Phase 2 | Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases | June 2008 | January 31, 2030 |
NCT01476839 | Active, not recruiting | Phase 1 | Radiolabeled Monoclonal Antibody Therapy and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Primary Refractory or Relapsed Hodgkin Lymphoma | November 9, 2012 | December 31, 2024 |
NCT01840566 | Active, not recruiting | Phase 1 | High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma | April 2013 | April 2025 |
NCT02443077 | Active, not recruiting | Phase 3 | Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma | October 12, 2016 | May 10, 2025 |
NCT02797470 | Active, not recruiting | Phase 1/Phase 2 | Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant | June 23, 2016 | June 30, 2025 |
NCT02896582 | Active, not recruiting | Phase 2 | Efficacy of Upfront and Maintenance Obinutuzumab in Mantle Cell Lymphoma Treated by DHAP and MRD Driven Maintenance | October 2016 | March 2025 |
NCT02342782 | Active, not recruiting | Phase 1 | Yttrium Y 90 Basiliximab and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Mature T-cell Non-Hodgkin Lymphoma | June 8, 2020 | December 31, 2024 |
NCT02329080 | Active, not recruiting | Phase 2 | New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System Involvement | December 2014 | December 2023 |
NCT00641381 | Active, not recruiting | Phase 1 | Carmustine, Etoposide, Cyclophosphamide, and Stem Cell Transplant in Treating Patients With HIV-Associated Lymphoma | May 10, 2000 | December 30, 2024 |
NCT00002766 | Completed | Phase 3 | Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma | March 1996 | September 2011 |
NCT00002835 | Completed | Phase 3 | Combination Chemotherapy in Treating Patients With Lymphoma | October 30, 1995 | February 4, 2004 |
NCT00002836 | Completed | Phase 3 | Filgrastim Plus Chemotherapy Compared With Filgrastim Alone In Treating Women Undergoing Peripheral Stem Cell Transplantation For Breast Cancer | September 26, 1995 | March 9, 2006 |
NCT00002941 | Completed | Phase 2 | Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Hodgkin's or Non-Hodgkin's Lymphoma | April 1998 | March 2007 |
NCT00002982 | Completed | Phase 2 | Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Older Patients With Refractory or Relapsed Intermediate-Grade Non-Hodgkin's Lymphoma | January 1997 | October 2005 |
NCT00002986 | Completed | Phase 1 | Chemotherapy in Treating Patients With Recurrent Malignant Glioma | February 1997 | May 2004 |
NCT00002988 | Completed | Phase 1 | Irinotecan Plus Carmustine in Treating Patients With Recurrent Primary Malignant Glioma | April 1997 | November 2000 |
NCT00003176 | Completed | Phase 2 | Temozolomide and Carmustine in Treating Patients With Anaplastic Glioma | March 25, 1998 | January 6, 2004 |
NCT00003346 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma | November 1997 | February 2003 |
NCT00003348 | Completed | Phase 1 | Carmustine Plus O(6)-Benzylguanine in Treating Patients With Recurrent or Progressive Gliomas of the Brain | May 1998 | August 2000 |
NCT00003397 | Completed | Phase 2 | Peripheral Stem Cell Transplantation Plus Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma | September 1998 | December 2002 |
NCT00003399 | Completed | Phase 2 | Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma | September 1998 | September 2002 |
NCT00003400 | Completed | Phase 2 | Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Prostate Cancer | September 1998 | March 2000 |
NCT00003401 | Completed | Phase 2 | Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma | January 1999 | September 2002 |
NCT00003402 | Completed | Phase 2 | Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia | January 1999 | December 2002 |
NCT00003413 | Completed | Phase 2 | Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer | September 1998 | February 2001 |
NCT00003417 | Completed | Phase 1/Phase 2 | Computer Planned Radiation Therapy Plus Chemotherapy in Treating Patients With Glioblastoma Multiforme | September 1998 | |
NCT00003463 | Completed | Phase 1 | Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas | July 1998 | July 2002 |
NCT00003467 | Completed | Phase 2 | Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma | January 1998 | February 2004 |
NCT00003484 | Completed | Phase 1 | Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors | September 1997 | March 2010 |
NCT00003543 | Completed | Phase 1 | Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | June 1998 | August 2002 |
NCT00003621 | Completed | Phase 2 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Anaplastic Astrocytoma | February 1999 | July 2005 |
NCT00003631 | Completed | Phase 2 | Chemotherapy Plus Radiation Therapy in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma | August 1998 | |
NCT00003632 | Completed | Phase 2 | Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Central Nervous System Lymphoma | September 1998 | |
NCT00003727 | Completed | Phase 2 | Chemotherapy and Peripheral Stem Cell Transplantation Followed by Immunotherapy in Treating Patients With Chronic Myelogenous Leukemia | March 1999 | February 2008 |
NCT00003765 | Completed | Phase 1 | O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors | May 1999 | |
NCT00003996 | Completed | Phase 2 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | May 1999 | May 2008 |
NCT00004028 | Completed | Phase 1 | Carmustine in Treating Patients With Recurrent Malignant Glioma | September 1996 | |
NCT00004031 | Completed | Phase 3 | SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma | July 1997 | October 31, 2013 |
NCT00004072 | Completed | Phase 2 | O6-benzylguanine And Carmustine in Treating Patients With Multiple Myeloma | September 1999 | September 2004 |
NCT00004688 | Completed | Phase 2 | Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms | August 1996 | July 1998 |
NCT00005066 | Completed | Phase 2 | O6-benzylguanine and Carmustine in Treating Patients With Recurrent, Metastatic, or Locally Advanced Soft Tissue Sarcoma | June 2000 | October 2002 |
NCT00005081 | Completed | Phase 2 | Carmustine Plus O6-benzylguanine in Treating Patients With Recurrent or Progressive Glioma | August 2000 | April 2001 |
NCT00005589 | Completed | Phase 3 | Combination Chemotherapy Plus Peripheral Stem Cell Transplantation With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma | October 1999 | April 2013 |
NCT00005637 | Completed | Phase 1 | Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma | December 1999 | December 2009 |
NCT00005803 | Completed | Phase 1/Phase 2 | Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma | September 1999 | October 2018 |
NCT00005855 | Completed | Phase 1/Phase 2 | Efaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant Glioma | July 2000 | October 2006 |
NCT00005961 | Completed | Phase 2 | O6-benzylguanine and Carmustine in Treating Patients With Unresectable Locally Recurrent or Metastatic Melanoma | June 2000 | |
NCT00005981 | Completed | Phase 2 | Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer | June 2000 | November 2003 |
NCT00005985 | Completed | Phase 2 | Filgrastim and Chemotherapy Followed by Peripheral Stem Cell Transplant in Treating Patients With Hodgkin's Lymphoma or Non-Hodgkin's Lymphoma | August 2000 | February 2007 |
NCT01035463 | Completed | Phase 1/Phase 2 | Lenalidomide Therapy After Chemotherapy & Stem Cell Transplant in Treating Chemotherapy Resistan Non-Hodgkin Lymphoma | November 12, 2009 | July 27, 2018 |
NCT00002545 | Completed | Phase 3 | Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme | February 1994 | |
NCT00002548 | Completed | Phase 3 | SWOG-9321 Melphalan, TBI, and Transplant vs Combo Chemo in Untreated Myeloma | January 1994 | November 2006 |
NCT00002552 | Completed | Phase 2 | Chemotherapy Plus Bone Marrow Transplantation in Treating Patients With Refractory Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Multiple Myeloma | October 1993 | October 2003 |
NCT00002556 | Completed | Phase 3 | Combination Chemotherapy With or Without High Dose Cyclophosphamide and Recombinant Interferon Alfa-2b in Treating Patients With Previously Untreated Stage I-III Multiple Myeloma | July 1994 | |
NCT00002604 | Completed | Phase 1 | O(6)-Benzylguanine and Carmustine in Treating Patients With Solid Tumors | January 1996 | February 2004 |
NCT00002620 | Completed | Phase 3 | Radiation Therapy in Treating Patients With Brain Cancer | November 1994 | |
NCT00002638 | Completed | Phase 2 | Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Relapsed Acute Lymphocytic Leukemia | March 1995 | March 2005 |
NCT00002676 | Completed | Phase 2 | Chemotherapy and Whole-Brain Radiation Therapy in Treating Patients With Primary Central Nervous System Non- Hodgkin's Lymphoma | July 1995 | October 2006 |
NCT00002719 | Completed | Phase 3 | Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia | December 1995 | |
NCT00006386 | Completed | Phase 2 | Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme | March 2001 | February 2009 |
NCT00006695 | Completed | Phase 2 | Monoclonal Antibody Therapy, Combination Chemotherapy, and Peripheral Stem Cell Transplant in Non-Hodgkin's Lymphoma | April 1, 2000 | December 16, 2014 |
NCT00006747 | Completed | Phase 2 | Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma | November 2000 | February 2003 |
NCT00007852 | Completed | Phase 2 | Rituximab & Combination Chemotherapy Followed by Transplantation in Relapsed or Refractory Non-Hodgkin's Lymphoma | September 1, 2000 | January 1, 2011 |
NCT00007982 | Completed | Phase 2 | Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients With Central Nervous System Cancer | April 1999 | May 2008 |
NCT00012051 | Completed | Phase 3 | Chemotherapy and Peripheral Stem Cell Transplant With or Without Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma | September 2000 | October 2007 |
NCT00014573 | Completed | Phase 2 | Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer | August 1998 | October 2004 |
NCT00017147 | Completed | Phase 3 | S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma | September 2001 | November 2012 |
NCT00020943 | Completed | Phase 2 | Chemotherapy and Rituximab With Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma | June 2001 | September 2009 |
NCT00027612 | Completed | Phase 1/Phase 2 | Irinotecan Plus Radiation Therapy Followed By Chemotherapy in Treating Patients With Glioblastoma Multiforme | July 2002 | July 2009 |
NCT00028665 | Completed | Phase 2 | Cyclophosphamide W/or W/Out Rituximab and Peripheral Stem Cell Transplantation in Patients With Recurrent Non-Hodgkin's Lymphoma | June 2000 | |
NCT00046852 | Completed | Phase 1/Phase 2 | Chemotherapy and Peripheral Stem Cell Transplantation Followed By Immunotherapy in Treating Patients With Multiple Myeloma | December 2001 | February 2008 |
NCT00052923 | Completed | Phase 3 | Stem Cell Transplantation With or Without Rituximab in Treating Patients With Relapsed or Progressive B-Cell Diffuse Large Cell Lymphoma | March 2003 | |
NCT00058292 | Completed | Phase 1 | Radiolabeled Monoclonal Antibody Therapy and High-Dose Chemotherapy Followed By Autologous Peripheral Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma | April 2000 | March 2009 |
NCT00060255 | Completed | Phase 2 | High-Dose Chemotherapy, Total-Body Irradiation, and Autologous Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Hematologic Cancer or Solid Tumors | December 1991 | February 2013 |
NCT00070187 | Completed | Phase 2/Phase 3 | Immunotherapy Using Cyclosporine, Interferon Gamma, and Interleukin-2 After High-Dose Myeloablative Chemotherapy With Autologous Stem Cell Transplantation in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma | November 2003 | |
NCT00080886 | Completed | Phase 2 | Rituximab, Carmustine; Cytarabine, Etoposide, & Melphalan; Stem Cell Transplantation for Non-Hodgkin's Lymphoma | May 8, 2002 | March 12, 2015 |
NCT00086879 | Completed | Phase 2 | Erlotinib Compared With Temozolomide or Carmustine in Treating Patients With Recurrent Glioblastoma Multiforme | May 2004 | March 2011 |
NCT00233987 | Completed | Phase 2 | S0410 Tandem Stem Cell Transplantation in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma | October 2005 | December 2017 |
NCT00242996 | Completed | Phase 2 | Rituximab, Cyclophosphamide, and G-CSF Followed By Combination Chemotherapy in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant Followed By Rituximab and GM-CSF for Refractory Diffuse Large B-Cell Lymphoma | March 2004 | April 2007 |
NCT00244946 | Completed | Phase 1 | Combination Chemotherapy Followed By Autologous Stem Cell Transplant, and White Blood Cell Infusions in Treating Patients With Non-Hodgkin's Lymphoma | March 2004 | March 2013 |
NCT00275015 | Completed | Phase 2 | Cyclophosphamide and Total Body Irradiation in Treating Patients Who Are Undergoing an Autologous Peripheral Stem Cell Transplant For Chronic Lymphocytic Leukemia | January 1998 | April 2012 |
NCT00276809 | Completed | Phase 2 | Combination Chemotherapy, Total-Body Irradiation, and Alemtuzumab in Treating Patients Undergoing an Autologous Stem Cell Transplant for Stage I, Stage II, Stage III, or Stage IV Chronic Lymphocytic Leukemia | June 2001 | September 2004 |
NCT00345865 | Completed | Phase 2 | Autologous Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma | August 24, 2005 | June 28, 2019 |
NCT00349778 | Completed | Phase 2 | High-Dose Sequential Therapy and Single Autologous Transplantation for Multiple Myeloma | August 2006 | April 2010 |
NCT00388349 | Completed | Phase 2 | Gemcitabine and Hodgkin's Disease Chemotherapy Followed by Peripheral Blood Stem Cell Rescue for Hodgkin's Disease | September 2001 | September 2010 |
NCT00439556 | Completed | Phase 2 | Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant | February 13, 2007 | June 7, 2018 |
NCT00472056 | Completed | Phase 2 | Rituximab in Addition to Autologous Transplantation With BEAM for Patients With Lymphoid Malignancies | March 2005 | June 2012 |
NCT00521014 | Completed | Phase 2 | GM-CSF and Rituximab After Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Follicular Non-Hodgkin Lymphoma | October 2007 | July 2013 |
NCT00536601 | Completed | N/A | High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors | June 29, 2006 | July 9, 2018 |
NCT00544570 | Completed | N/A | High-Dose Chemotherapy in Treating Patients Undergoing Stem Cell Transplant for Recurrent or Refractory Hodgkin's Lymphoma | April 1998 | December 2007 |
NCT00559104 | Completed | Phase 2 | Combination Chemotherapy With or Without Total-Body Irradiation Followed By Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma | October 1998 | July 2011 |
NCT00569985 | Completed | Phase 1 | Gene Therapy-Treated Stem Cells in Treating Patients Undergoing Stem Cell Transplant for Intermediate-Grade or High-Grade AIDS-Related Lymphoma | June 2007 | November 12, 2019 |
NCT00591630 | Completed | Phase 2 | Zevalin/BEAM/Rituximab vs BEAM/Rituximab With or Without Rituximab in Autologous Stem Cell Transplantation | November 14, 2007 | March 5, 2020 |
NCT00691015 | Completed | Phase 2 | Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant | May 2008 | April 2014 |
NCT00695409 | Completed | Phase 2 | Yttrium-90 Ibritumomab Tiuxetan Plus High-Dose BEAM Followed By ASCT For Relapsed B-Cell Non-Hodgkin Lymphoma | March 18, 2008 | March 27, 2017 |
NCT00795665 | Completed | Phase 2 | Bevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade Glioma | June 2008 | December 2015 |
NCT00961220 | Completed | Phase 1/Phase 2 | O6-Benzylguanine and Topical Carmustine in Treating Patients With Early-Stage IA-IIA Cutaneous T-Cell Lymphoma | February 1, 2010 | April 8, 2014 |
NCT00968760 | Completed | Phase 1 | CD19-specific T Cell Infusion in Patients With B-Lineage Lymphoid Malignancies | June 20, 2011 | April 23, 2020 |
NCT00992446 | Completed | Phase 2 | Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma | September 2, 2010 | October 29, 2019 |
NCT01008462 | Completed | Phase 2 | Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia | March 18, 2010 | June 30, 2018 |
NCT00002461 | Completed | Phase 2 | Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Refractory Hodgkin's Disease or Non-Hodgkin's Lymphoma | April 1988 | July 1991 |
NCT01921387 | Completed | Phase 1/Phase 2 | Radiolabeled Monoclonal Antibody and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With High-Risk Lymphoid Malignancies | October 9, 2013 | July 26, 2020 |
NCT01969435 | Completed | Phase 2 | Study of Melphalan HCl for Injection (Propylene Glycol-free), Carmustine, Etoposide, Cytarabine (BEAM Regimen) and Autologous Stem Cell Transplantation for Lymphoma | March 19, 2014 | May 31, 2017 |
NCT02059239 | Completed | Phase 1/Phase 2 | Bendamustine Bridge to Autologous or Allogeneic Transplant for Relapsed/Refractory Lymphoma | June 4, 2014 | June 15, 2020 |
NCT02504359 | Completed | Phase 1 | Combination Chemotherapy and Donor Stem Cell Transplant Followed by Ixazomib Citrate Maintenance Therapy in Treating Patients With Relapsed High-Risk Multiple Myeloma | July 20, 2015 | September 9, 2020 |
NCT03019640 | Completed | Phase 2 | Umbilical Cord Blood NK Cells, Rituximab, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma | October 10, 2017 | August 16, 2021 |
NCT03072771 | Completed | Phase 1 | Blinatumomab Consolidation Post Autologous Stem Cell Transplantation in Patients With Diffuse Large B-Cell Lymphoma (DLBCL) | August 1, 2017 | October 30, 2023 |
NCT03722355 | Completed | Phase 3 | Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma | November 9, 1990 | October 18, 2002 |
NCT06377540 | Not yet recruiting | Phase 2 | MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma | August 1, 2024 | September 1, 2027 |
NCT05863845 | Not yet recruiting | N/A | Efficacy and Safety of Venetoclax Combined With BEAM Pretreatment in Autologous Transplantation for DLBCL | June 1, 2023 | November 30, 2025 |
NCT03570983 | Recruiting | Phase 2 | A Trial Comparing Single Agent Melphalan to Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell Reinfusion | September 5, 2018 | December 2024 |
NCT05521984 | Recruiting | Phase 1 | Targeting Pediatric Brain Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i) | April 3, 2023 | November 30, 2026 |
NCT05466318 | Recruiting | Phase 3 | ChiCGB vs BEAM in High-risk or R/R Lymphomas | July 1, 2022 | December 30, 2025 |
NCT03736616 | Recruiting | Phase 2 | Acalabrutinib Plus RICE for Relapsed/Refractory DLBCL | August 16, 2019 | September 2023 |
NCT03382977 | Recruiting | Phase 1/Phase 2 | Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects | December 6, 2017 | August 2025 |
NCT04728633 | Recruiting | Phase 2 | Transarterial Chemoembolization for the Treatment of Uveal Melanoma With Liver Metastases | September 27, 2021 | March 31, 2026 |
NCT04871607 | Recruiting | Phase 2 | Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma | November 2, 2021 | October 2, 2027 |
NCT05052957 | Recruiting | Phase 2 | hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) | January 20, 2023 | December 1, 2024 |
NCT00632827 | Terminated | Phase 2 | Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak) | July 1, 2008 | June 23, 2016 |
NCT00003613 | Terminated | Phase 1 | O6-benzylguanine and Carmustine in Treating Patients With Stage IA-IIA Cutaneous T-cell Lymphoma | April 1999 | |
NCT04421378 | Terminated | Phase 1/Phase 2 | A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma | June 8, 2020 | July 3, 2023 |
NCT00003567 | Terminated | Phase 1 | Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma | May 1999 | February 2007 |
NCT00761280 | Terminated | Phase 3 | Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma | December 2008 | June 2012 |
NCT01220297 | Terminated | Phase 2 | Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT | August 2006 | August 2011 |
NCT00669669 | Terminated | Phase 1/Phase 2 | O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas | February 25, 2009 | January 20, 2021 |
NCT01500161 | Terminated | Phase 2 | Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic Stem Cell Transplant Without Related HLA-Match | November 2011 | November 2013 |
NCT00005987 | Terminated | Phase 2 | Filgrastim Compared With Sargramostim Plus Chemotherapy, Peripheral Stem Cell Transplantation, and Interferon Alfa in Treating Patients With Multiple Myeloma | August 2000 | July 2003 |
NCT00005090 | Terminated | Phase 3 | S9901 Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Men With Stage III or Stage IV Hodgkin's Disease | April 2000 | May 2005 |
NCT01653418 | Terminated | Phase 2 | Phase II Study of V-BEAM Conditioning Regimen Prior to Second Autologous Stem Cell Transplantation | September 2012 | December 2013 |
NCT00281879 | Terminated | Phase 2 | Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer | February 2006 | March 2008 |
NCT00920153 | Terminated | Phase 3 | Three Different Therapy Regimens in Treating Patients With Previously Untreated Hodgkin Lymphoma | May 2008 | March 2016 |
NCT01692691 | Terminated | Phase 2 | Dacarbazine and Carmustine in Metastatic Melanoma | August 2012 | October 2014 |
NCT02366663 | Terminated | Phase 3 | BEAM vs. 90-Yttrium Ibritumomab Tiuxetan (Zevalin®)/BEAM With ASCT for Relapsed DLBCL | January 2015 | October 2016 |
NCT00002772 | Terminated | Phase 3 | S9623, Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer | July 1996 | February 2004 |
NCT02483000 | Terminated | Phase 1 | Anti-CD20 Radioimmunotherapy Before Chemotherapy and Stem Cell Transplant in Treating Patients With High-Risk B-Cell Malignancies | February 1, 2017 | September 2, 2020 |
NCT00482053 | Terminated | Phase 2 | Phase 2 Poor Risk DLBCL of TLI and ATG Followed by Matched Allogeneic HT as Consolidation to Autologous HCT | October 2006 | May 2010 |
NCT00317408 | Unknown status | N/A | Combination Chemotherapy Followed By Stem Cell Transplant in Treating Young Patients With Progressive or Relapsed Anaplastic Large Cell Lymphoma | April 2004 | |
NCT00908180 | Unknown status | Phase 2 | Carmustine, Etoposide, Cytarabine, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma | July 2009 | |
NCT03583424 | Unknown status | Phase 1/Phase 2 | Venetoclax, Carmustine, Etoposide, Cytarabine, and Melphalan Before Stem Cell Transplant in Treating Participants With Relapsed or Refractory Non-Hodgkin Lymphoma | September 10, 2018 | December 31, 2022 |
NCT00016887 | Unknown status | Phase 3 | Chemotherapy Followed by Radiation Therapy and Peripheral Stem Cell Transplant Compared With Chemotherapy Plus Interferon Alfa in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma | December 2000 | |
NCT00025636 | Unknown status | Phase 3 | Combination Chemotherapy and Peripheral Stem Cell Transplant in Treating Patients With Relapsed Hodgkin's Lymphoma | July 2001 | |
NCT00003815 | Unknown status | Phase 3 | Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma | June 1994 | |
NCT00003788 | Unknown status | Phase 3 | Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas | April 1998 | |
NCT01656980 | Unknown status | Phase 3 | Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Newly Diagnosed Malignant Glioma | August 2012 | December 2014 |
NCT00003578 | Unknown status | Phase 3 | High Dose Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma | January 1993 | |
NCT00720447 | Unknown status | Phase 2 | Donor Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma | November 2008 | |
NCT02670109 | Unknown status | Phase 2 | Autologous Hematopoietic Stem Cell Transplantation as Adjuvant Treatment for Triple Negative Breast Cancer Patients | February 1, 2018 | November 2021 |
NCT00002653 | Unknown status | Phase 3 | Combination Chemotherapy With or Without Cyclophosphamide and Prednisone in Treating Older Patients With Multiple Myeloma | September 1993 | |
NCT00002599 | Unknown status | Phase 3 | Combination Chemotherapy and Interferon Alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma | September 1994 | |
NCT00669812 | Unknown status | Phase 2 | High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma | February 2008 | |
NCT02343666 | Withdrawn | Phase 1 | HIV-Resistant Gene Modified Stem Cells and Chemotherapy in Treating Patients With Lymphoma With HIV Infection | August 15, 2016 | |
NCT05228249 | Withdrawn | Phase 1 | Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma | April 2023 | October 1, 2027 |
NCT01769911 | Withdrawn | N/A | Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma | February 2015 | |
NCT00046878 | Withdrawn | Phase 2 | Carmustine and O(6)-Benzylguanine in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme | August 2002 | |
NCT03579927 | Withdrawn | Phase 1/Phase 2 | CAR.CD19-CD28-zeta-2A-iCasp9-IL15-Transduced Cord Blood NK Cells, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Participants With B-cell Lymphoma | October 3, 2019 | October 3, 2019 |
NCT02348255 | Withdrawn | Phase 2 | NovoTTF-100A With Bevacizumab and Carmustine in Treating Patients With Glioblastoma Multiforme in First Relapse | January 2016 | January 2017 |
NCT00723658 | Withdrawn | Phase 2 | S0629, Observation or Combination Chemotherapy, Bortezomib, Thalidomide, and Rituximab Followed By Two Autologous Peripheral Blood Stem Cell Transplants in Treating Patients With Waldenstrom Macroglobulinemia | September 2008 | |
NCT00006123 | Withdrawn | Phase 1/Phase 2 | Chemotherapy and Peripheral Stem Cell Transplantation Followed by Trastuzumab in Treating Women With Metastatic Breast Cancer | July 2000 | July 2000 |
NCT00005998 | Withdrawn | Phase 2 | Peripheral Stem Cell Transplantation With Specially Treated Stem Cells in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease | January 2000 | March 2003 |